JP2018514208A5 - - Google Patents

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Publication number
JP2018514208A5
JP2018514208A5 JP2017555766A JP2017555766A JP2018514208A5 JP 2018514208 A5 JP2018514208 A5 JP 2018514208A5 JP 2017555766 A JP2017555766 A JP 2017555766A JP 2017555766 A JP2017555766 A JP 2017555766A JP 2018514208 A5 JP2018514208 A5 JP 2018514208A5
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JP
Japan
Prior art keywords
nucleic acid
acid construct
construct according
signal
intracellular retention
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Application number
JP2017555766A
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English (en)
Japanese (ja)
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JP2018514208A (ja
JP6836515B2 (ja
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Priority claimed from GBGB1507104.6A external-priority patent/GB201507104D0/en
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Publication of JP2018514208A publication Critical patent/JP2018514208A/ja
Publication of JP2018514208A5 publication Critical patent/JP2018514208A5/ja
Application granted granted Critical
Publication of JP6836515B2 publication Critical patent/JP6836515B2/ja
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JP2017555766A 2015-04-27 2016-04-26 核酸構築物 Active JP6836515B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1507104.6A GB201507104D0 (en) 2015-04-27 2015-04-27 Nucleic acid construct
GB1507104.6 2015-04-27
PCT/GB2016/051164 WO2016174408A1 (en) 2015-04-27 2016-04-26 Nucleic acid construct

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020117039A Division JP2020171313A (ja) 2015-04-27 2020-07-07 核酸構築物

Publications (3)

Publication Number Publication Date
JP2018514208A JP2018514208A (ja) 2018-06-07
JP2018514208A5 true JP2018514208A5 (https=) 2019-04-11
JP6836515B2 JP6836515B2 (ja) 2021-03-03

Family

ID=53488689

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017555766A Active JP6836515B2 (ja) 2015-04-27 2016-04-26 核酸構築物
JP2020117039A Withdrawn JP2020171313A (ja) 2015-04-27 2020-07-07 核酸構築物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2020117039A Withdrawn JP2020171313A (ja) 2015-04-27 2020-07-07 核酸構築物

Country Status (10)

Country Link
US (1) US11530420B2 (https=)
EP (1) EP3288968B1 (https=)
JP (2) JP6836515B2 (https=)
CN (1) CN107532176A (https=)
AU (1) AU2016254498B2 (https=)
CA (1) CA2984101A1 (https=)
ES (1) ES2847698T3 (https=)
GB (1) GB201507104D0 (https=)
HK (1) HK1244021A1 (https=)
WO (1) WO2016174408A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3143134T3 (da) 2014-05-15 2021-01-04 Nat Univ Singapore Modificerede, naturlige dræberceller og anvendelser deraf
GB201507108D0 (en) 2015-04-27 2015-06-10 Ucl Business Plc Nucleic acid construct
JP2018526007A (ja) * 2015-09-04 2018-09-13 トカジェン インコーポレーテッド 2aペプチドを含む組換えベクター
NZ752984A (en) 2016-11-22 2026-03-27 Nat Univ Singapore Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies
CA3057838A1 (en) * 2017-03-24 2018-09-27 Lentigen Technology, Inc. Compositions and methods for treating cancer with anti-cd33 immunotherapy
CA3056591A1 (en) 2017-03-27 2018-10-04 National University Of Singapore Stimulatory cell lines for ex vivo expansion and activation of natural killer cells
BR112019019917A2 (pt) 2017-03-27 2020-04-22 Nat Univ Singapore receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais
US11389525B2 (en) 2017-10-27 2022-07-19 Statens Serum Institut Polygene influenza vaccine
CN108359014A (zh) * 2018-02-08 2018-08-03 四川农业大学 含有dhav-1 2a1-p的多肽及其介导的多蛋白共表达方法
EP3749685A4 (en) 2018-02-09 2021-12-22 National University of Singapore ACTIVATOR CHEMERIC RECEPTORS AND THEIR USES IN NATURAL KILLING CELL IMMUNOTHERAPY
JP7334985B2 (ja) 2018-04-02 2023-08-29 ナショナル ユニヴァーシティー オブ シンガポール 免疫細胞で発現される膜結合抗サイトカイン非シグナル伝達バインダーによるヒトサイトカインの中和
GB201805918D0 (en) 2018-04-10 2018-05-23 Autolus Ltd Cell
CA3110282A1 (en) * 2018-08-24 2020-02-27 Locanabio, Inc. Fasl immunomodulatory gene therapy compositions and methods for use
EP3844186A4 (en) 2018-08-29 2022-08-17 National University of Singapore METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
CA3120563A1 (en) 2018-11-26 2020-06-04 Nkarta, Inc. Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
EP3773918A4 (en) 2019-03-05 2022-01-05 Nkarta, Inc. CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY
GB201914611D0 (en) * 2019-10-09 2019-11-20 Autolus Ltd Engineered immune cell
WO2024197792A1 (en) * 2023-03-31 2024-10-03 Beijing University Of Chinese Medicine A complex comprising a cell penetrating peptide and a copi sorting inhibitor and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU733719B2 (en) * 1996-10-23 2001-05-24 Trustees Of The University Of Pennsylvania, The Improved vaccines
MX2008000985A (es) * 2005-07-21 2008-04-07 Abbott Lab Expresion de gen multiple que incluye construcciones y metodos sorf (cuadro de lectura abierta simple) con poliproteinas, pro-proteinas y proteolisis.
CN103483452B (zh) * 2012-06-12 2021-08-13 上海细胞治疗集团有限公司 双信号独立的嵌合抗原受体及其用途
KR20150087321A (ko) 2012-11-21 2015-07-29 메르츠 파마 게엠베하 운트 코. 카가아 보툴리눔 신경독소 생물학적 활성의 결정을 위한 수단 및 방법
US10934346B2 (en) * 2014-02-14 2021-03-02 Bellicum Pharmaceuticals, Inc. Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12
MX2017009657A (es) 2015-01-26 2017-12-07 United States Mineral Prod Co Materiales resistentes al fuego aplicados por pulverizacion resistentes a la corrosion.

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