JP2018514208A5 - - Google Patents
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- Publication number
- JP2018514208A5 JP2018514208A5 JP2017555766A JP2017555766A JP2018514208A5 JP 2018514208 A5 JP2018514208 A5 JP 2018514208A5 JP 2017555766 A JP2017555766 A JP 2017555766A JP 2017555766 A JP2017555766 A JP 2017555766A JP 2018514208 A5 JP2018514208 A5 JP 2018514208A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid construct
- construct according
- signal
- intracellular retention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1507104.6A GB201507104D0 (en) | 2015-04-27 | 2015-04-27 | Nucleic acid construct |
| GB1507104.6 | 2015-04-27 | ||
| PCT/GB2016/051164 WO2016174408A1 (en) | 2015-04-27 | 2016-04-26 | Nucleic acid construct |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020117039A Division JP2020171313A (ja) | 2015-04-27 | 2020-07-07 | 核酸構築物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018514208A JP2018514208A (ja) | 2018-06-07 |
| JP2018514208A5 true JP2018514208A5 (https=) | 2019-04-11 |
| JP6836515B2 JP6836515B2 (ja) | 2021-03-03 |
Family
ID=53488689
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017555766A Active JP6836515B2 (ja) | 2015-04-27 | 2016-04-26 | 核酸構築物 |
| JP2020117039A Withdrawn JP2020171313A (ja) | 2015-04-27 | 2020-07-07 | 核酸構築物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020117039A Withdrawn JP2020171313A (ja) | 2015-04-27 | 2020-07-07 | 核酸構築物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11530420B2 (https=) |
| EP (1) | EP3288968B1 (https=) |
| JP (2) | JP6836515B2 (https=) |
| CN (1) | CN107532176A (https=) |
| AU (1) | AU2016254498B2 (https=) |
| CA (1) | CA2984101A1 (https=) |
| ES (1) | ES2847698T3 (https=) |
| GB (1) | GB201507104D0 (https=) |
| HK (1) | HK1244021A1 (https=) |
| WO (1) | WO2016174408A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3143134T3 (da) | 2014-05-15 | 2021-01-04 | Nat Univ Singapore | Modificerede, naturlige dræberceller og anvendelser deraf |
| GB201507108D0 (en) | 2015-04-27 | 2015-06-10 | Ucl Business Plc | Nucleic acid construct |
| JP2018526007A (ja) * | 2015-09-04 | 2018-09-13 | トカジェン インコーポレーテッド | 2aペプチドを含む組換えベクター |
| NZ752984A (en) | 2016-11-22 | 2026-03-27 | Nat Univ Singapore | Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies |
| CA3057838A1 (en) * | 2017-03-24 | 2018-09-27 | Lentigen Technology, Inc. | Compositions and methods for treating cancer with anti-cd33 immunotherapy |
| CA3056591A1 (en) | 2017-03-27 | 2018-10-04 | National University Of Singapore | Stimulatory cell lines for ex vivo expansion and activation of natural killer cells |
| BR112019019917A2 (pt) | 2017-03-27 | 2020-04-22 | Nat Univ Singapore | receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais |
| US11389525B2 (en) | 2017-10-27 | 2022-07-19 | Statens Serum Institut | Polygene influenza vaccine |
| CN108359014A (zh) * | 2018-02-08 | 2018-08-03 | 四川农业大学 | 含有dhav-1 2a1-p的多肽及其介导的多蛋白共表达方法 |
| EP3749685A4 (en) | 2018-02-09 | 2021-12-22 | National University of Singapore | ACTIVATOR CHEMERIC RECEPTORS AND THEIR USES IN NATURAL KILLING CELL IMMUNOTHERAPY |
| JP7334985B2 (ja) | 2018-04-02 | 2023-08-29 | ナショナル ユニヴァーシティー オブ シンガポール | 免疫細胞で発現される膜結合抗サイトカイン非シグナル伝達バインダーによるヒトサイトカインの中和 |
| GB201805918D0 (en) | 2018-04-10 | 2018-05-23 | Autolus Ltd | Cell |
| CA3110282A1 (en) * | 2018-08-24 | 2020-02-27 | Locanabio, Inc. | Fasl immunomodulatory gene therapy compositions and methods for use |
| EP3844186A4 (en) | 2018-08-29 | 2022-08-17 | National University of Singapore | METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS |
| CA3120563A1 (en) | 2018-11-26 | 2020-06-04 | Nkarta, Inc. | Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy |
| EP3773918A4 (en) | 2019-03-05 | 2022-01-05 | Nkarta, Inc. | CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY |
| GB201914611D0 (en) * | 2019-10-09 | 2019-11-20 | Autolus Ltd | Engineered immune cell |
| WO2024197792A1 (en) * | 2023-03-31 | 2024-10-03 | Beijing University Of Chinese Medicine | A complex comprising a cell penetrating peptide and a copi sorting inhibitor and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU733719B2 (en) * | 1996-10-23 | 2001-05-24 | Trustees Of The University Of Pennsylvania, The | Improved vaccines |
| MX2008000985A (es) * | 2005-07-21 | 2008-04-07 | Abbott Lab | Expresion de gen multiple que incluye construcciones y metodos sorf (cuadro de lectura abierta simple) con poliproteinas, pro-proteinas y proteolisis. |
| CN103483452B (zh) * | 2012-06-12 | 2021-08-13 | 上海细胞治疗集团有限公司 | 双信号独立的嵌合抗原受体及其用途 |
| KR20150087321A (ko) | 2012-11-21 | 2015-07-29 | 메르츠 파마 게엠베하 운트 코. 카가아 | 보툴리눔 신경독소 생물학적 활성의 결정을 위한 수단 및 방법 |
| US10934346B2 (en) * | 2014-02-14 | 2021-03-02 | Bellicum Pharmaceuticals, Inc. | Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12 |
| MX2017009657A (es) | 2015-01-26 | 2017-12-07 | United States Mineral Prod Co | Materiales resistentes al fuego aplicados por pulverizacion resistentes a la corrosion. |
-
2015
- 2015-04-27 GB GBGB1507104.6A patent/GB201507104D0/en not_active Ceased
-
2016
- 2016-04-26 WO PCT/GB2016/051164 patent/WO2016174408A1/en not_active Ceased
- 2016-04-26 CA CA2984101A patent/CA2984101A1/en not_active Abandoned
- 2016-04-26 US US15/568,859 patent/US11530420B2/en active Active
- 2016-04-26 ES ES16720483T patent/ES2847698T3/es active Active
- 2016-04-26 HK HK18103619.5A patent/HK1244021A1/zh unknown
- 2016-04-26 CN CN201680024069.5A patent/CN107532176A/zh active Pending
- 2016-04-26 AU AU2016254498A patent/AU2016254498B2/en not_active Ceased
- 2016-04-26 EP EP16720483.3A patent/EP3288968B1/en active Active
- 2016-04-26 JP JP2017555766A patent/JP6836515B2/ja active Active
-
2020
- 2020-07-07 JP JP2020117039A patent/JP2020171313A/ja not_active Withdrawn
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