JP2018514208A5 - - Google Patents
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- Publication number
- JP2018514208A5 JP2018514208A5 JP2017555766A JP2017555766A JP2018514208A5 JP 2018514208 A5 JP2018514208 A5 JP 2018514208A5 JP 2017555766 A JP2017555766 A JP 2017555766A JP 2017555766 A JP2017555766 A JP 2017555766A JP 2018514208 A5 JP2018514208 A5 JP 2018514208A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid construct
- construct according
- signal
- intracellular retention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1507104.6 | 2015-04-27 | ||
| GBGB1507104.6A GB201507104D0 (en) | 2015-04-27 | 2015-04-27 | Nucleic acid construct |
| PCT/GB2016/051164 WO2016174408A1 (en) | 2015-04-27 | 2016-04-26 | Nucleic acid construct |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020117039A Division JP2020171313A (ja) | 2015-04-27 | 2020-07-07 | 核酸構築物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018514208A JP2018514208A (ja) | 2018-06-07 |
| JP2018514208A5 true JP2018514208A5 (cg-RX-API-DMAC10.html) | 2019-04-11 |
| JP6836515B2 JP6836515B2 (ja) | 2021-03-03 |
Family
ID=53488689
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017555766A Active JP6836515B2 (ja) | 2015-04-27 | 2016-04-26 | 核酸構築物 |
| JP2020117039A Withdrawn JP2020171313A (ja) | 2015-04-27 | 2020-07-07 | 核酸構築物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020117039A Withdrawn JP2020171313A (ja) | 2015-04-27 | 2020-07-07 | 核酸構築物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11530420B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP3288968B1 (cg-RX-API-DMAC10.html) |
| JP (2) | JP6836515B2 (cg-RX-API-DMAC10.html) |
| CN (1) | CN107532176A (cg-RX-API-DMAC10.html) |
| AU (1) | AU2016254498B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2984101A1 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2847698T3 (cg-RX-API-DMAC10.html) |
| GB (1) | GB201507104D0 (cg-RX-API-DMAC10.html) |
| HK (1) | HK1244021A1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2016174408A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3805371A1 (en) | 2014-05-15 | 2021-04-14 | National University of Singapore | Modified natural killer cells and uses thereof |
| GB201507108D0 (en) | 2015-04-27 | 2015-06-10 | Ucl Business Plc | Nucleic acid construct |
| AU2016317936A1 (en) * | 2015-09-04 | 2018-03-08 | Tocagen Inc. | Recombinant vectors comprising 2A peptide |
| CN118581046A (zh) | 2016-11-22 | 2024-09-03 | 新加坡国立大学 | 用于t细胞恶性肿瘤免疫疗法的cd7表达阻滞剂和嵌合抗原受体 |
| AU2018240556B2 (en) * | 2017-03-24 | 2025-02-27 | Lentigen Technology, Inc. | Compositions and methods for treating cancer with anti-CD33 immunotherapy |
| MX2019011570A (es) | 2017-03-27 | 2019-11-18 | Nat Univ Singapore | Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales. |
| CN117363636A (zh) | 2017-03-27 | 2024-01-09 | 新加坡国立大学 | 一种编码嵌合受体的多核苷酸 |
| WO2019081750A1 (en) * | 2017-10-27 | 2019-05-02 | Statens Serum Institut | VACCINE AGAINST POLYGENIC INFLUENZA |
| CN108359014A (zh) * | 2018-02-08 | 2018-08-03 | 四川农业大学 | 含有dhav-1 2a1-p的多肽及其介导的多蛋白共表达方法 |
| JP7360174B2 (ja) | 2018-02-09 | 2023-10-12 | ナショナル ユニヴァーシティー オブ シンガポール | ナチュラルキラー細胞免疫療法における活性化キメラ受容体及びその使用 |
| US12441787B2 (en) | 2018-04-02 | 2025-10-14 | National University Of Singapore | Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells |
| GB201805918D0 (en) | 2018-04-10 | 2018-05-23 | Autolus Ltd | Cell |
| EP3841116A4 (en) * | 2018-08-24 | 2022-05-25 | Locanabio, Inc. | FASL IMMUNOMODULATING GENE THERAPY COMPOSITIONS AND METHODS OF USE |
| WO2020044239A1 (en) | 2018-08-29 | 2020-03-05 | National University Of Singapore | A method to specifically stimulate survival and expansion of genetically-modified immune cells |
| CN113226340A (zh) | 2018-11-26 | 2021-08-06 | 恩卡尔塔公司 | 同时扩增多种免疫细胞类型的方法、相关组合物及其在癌症免疫疗法中的用途 |
| KR20210137085A (ko) | 2019-03-05 | 2021-11-17 | 엔카르타, 인크. | Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도 |
| GB201914611D0 (en) * | 2019-10-09 | 2019-11-20 | Autolus Ltd | Engineered immune cell |
| WO2024197792A1 (en) * | 2023-03-31 | 2024-10-03 | Beijing University Of Chinese Medicine | A complex comprising a cell penetrating peptide and a copi sorting inhibitor and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001503260A (ja) * | 1996-10-23 | 2001-03-13 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア | 改良されたワクチン |
| CN101595228A (zh) * | 2005-07-21 | 2009-12-02 | 艾博特公司 | 包括sorf构建体的多基因表达和使用多蛋白、前体蛋白和蛋白酶解的方法 |
| CN103483452B (zh) * | 2012-06-12 | 2021-08-13 | 上海细胞治疗集团有限公司 | 双信号独立的嵌合抗原受体及其用途 |
| EP2922866B1 (en) | 2012-11-21 | 2019-01-23 | Merz Pharma GmbH & Co. KGaA | Means and methods for determination of botulinum neurotoxin biological activity |
| EP3104866A4 (en) * | 2014-02-14 | 2017-08-02 | Bellicum Pharmaceuticals, Inc. | Methods for activating t cells using an inducible chimeric polypeptide |
| EA037575B1 (ru) | 2015-01-26 | 2021-04-15 | Юнайтед Стейтс Минерал Продактс Компани | Коррозионно-стойкие напыляемые огнестойкие материалы |
-
2015
- 2015-04-27 GB GBGB1507104.6A patent/GB201507104D0/en not_active Ceased
-
2016
- 2016-04-26 CN CN201680024069.5A patent/CN107532176A/zh active Pending
- 2016-04-26 HK HK18103619.5A patent/HK1244021A1/zh unknown
- 2016-04-26 CA CA2984101A patent/CA2984101A1/en not_active Abandoned
- 2016-04-26 ES ES16720483T patent/ES2847698T3/es active Active
- 2016-04-26 WO PCT/GB2016/051164 patent/WO2016174408A1/en not_active Ceased
- 2016-04-26 AU AU2016254498A patent/AU2016254498B2/en not_active Ceased
- 2016-04-26 EP EP16720483.3A patent/EP3288968B1/en not_active Not-in-force
- 2016-04-26 JP JP2017555766A patent/JP6836515B2/ja active Active
- 2016-04-26 US US15/568,859 patent/US11530420B2/en active Active
-
2020
- 2020-07-07 JP JP2020117039A patent/JP2020171313A/ja not_active Withdrawn
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