JP2018512401A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018512401A5 JP2018512401A5 JP2017548089A JP2017548089A JP2018512401A5 JP 2018512401 A5 JP2018512401 A5 JP 2018512401A5 JP 2017548089 A JP2017548089 A JP 2017548089A JP 2017548089 A JP2017548089 A JP 2017548089A JP 2018512401 A5 JP2018512401 A5 JP 2018512401A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- tumor
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562132374P | 2015-03-12 | 2015-03-12 | |
| US62/132,374 | 2015-03-12 | ||
| PCT/US2016/021843 WO2016145234A2 (en) | 2015-03-12 | 2016-03-10 | Use of mk2 inhibitor peptide-containing compositions for treating non-small cell lung cancer with same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018512401A JP2018512401A (ja) | 2018-05-17 |
| JP2018512401A5 true JP2018512401A5 (https=) | 2019-04-25 |
Family
ID=56880599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017548089A Pending JP2018512401A (ja) | 2015-03-12 | 2016-03-10 | Mk2阻害剤ペプチド含有組成物を用いた非小細胞肺癌の治療を目的とするその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9999655B2 (https=) |
| EP (1) | EP3268022A4 (https=) |
| JP (1) | JP2018512401A (https=) |
| KR (1) | KR20170125090A (https=) |
| CN (1) | CN107921082A (https=) |
| AU (1) | AU2016229017A1 (https=) |
| BR (1) | BR112017019343A2 (https=) |
| CA (1) | CA2978941A1 (https=) |
| HK (1) | HK1249433A1 (https=) |
| MX (1) | MX2017011633A (https=) |
| RU (1) | RU2017135072A (https=) |
| SG (1) | SG11201707281QA (https=) |
| WO (1) | WO2016145234A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018102827A1 (en) * | 2016-12-04 | 2018-06-07 | Expression Pathology, Inc. | Improved methods of treating lung cancer by predicting responders to cisplatin-pemetrexed combination therapy |
| CN110662844A (zh) | 2017-05-22 | 2020-01-07 | 内盖夫生物技术国家研究所有限公司 | 用于肺癌的诊断的生物标志物 |
| US10952799B2 (en) * | 2017-05-31 | 2021-03-23 | Covidien Lp | Systems and methods for navigational bronchoscopy and selective drug delivery |
| US20190134153A1 (en) * | 2017-06-12 | 2019-05-09 | Moerae Matrix, Inc. | Immunomodulatory effect of inhaled kinase inhibitor peptides in lung |
| CN112334150B (zh) * | 2018-06-12 | 2025-11-18 | 日内瓦大学 | 肽蛋白激酶c抑制剂及其用途 |
| US11195062B2 (en) | 2018-11-15 | 2021-12-07 | Nantomics, Llc | Classification based on characterization analysis methods and systems |
| EP4004548B1 (en) | 2019-07-29 | 2026-01-14 | Yeda Research and Development Co. Ltd | Methods of treating and diagnosing lung cancer |
| CN113261532A (zh) * | 2020-02-17 | 2021-08-17 | 中山大学 | 一种肺癌动物模型的构建方法 |
| US20230087078A1 (en) * | 2020-03-02 | 2023-03-23 | Washington University | Compositions and methods for the treatment of pancreatic cancer |
| CA3197627A1 (en) * | 2020-11-18 | 2022-05-27 | Kimberly SHEPARD | Inhalable dry powder formulations comprising angiogenesis inhibitors |
| MX2024008704A (es) | 2022-01-14 | 2024-07-22 | Shanghai Hansoh Biomedical Co Ltd | Derivado policiclico que contiene piridina, y metodo de preparacion de este y uso de este. |
| EP4608401A2 (en) * | 2022-10-27 | 2025-09-03 | Bristol-Myers Squibb Company | Mk2 inhibitors and uses thereof |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1521000A (en) | 1975-06-13 | 1978-08-09 | Syntex Puerto Rico Inc | Inhalation device |
| US4227522A (en) | 1978-09-05 | 1980-10-14 | Syntex Puerto Rico, Inc. | Inhalation device |
| US4192309A (en) | 1978-09-05 | 1980-03-11 | Syntex Puerto Rico, Inc. | Inhalation device with capsule opener |
| US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| DK172541B1 (da) | 1982-10-08 | 1998-12-07 | Glaxo Group Ltd | Apparat til administrering af medikamenter til patienter og en medikamentpakning til brug i apparatet |
| DE3682457D1 (de) | 1985-07-30 | 1991-12-19 | Glaxo Group Ltd | Geraet zur verabreichung von medikamenten an patienten. |
| JPH05963A (ja) | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
| US6331318B1 (en) | 1994-09-30 | 2001-12-18 | Emisphere Technologies Inc. | Carbon-substituted diketopiperazine delivery systems |
| US5352461A (en) | 1992-03-11 | 1994-10-04 | Pharmaceutical Discovery Corporation | Self assembling diketopiperazine drug delivery system |
| JPH07506252A (ja) | 1992-04-24 | 1995-07-13 | エス・アール・アイ・インターナシヨナル | 真核細胞内でのイン・ビボ相同配列ターゲッティング |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| EP0733059B1 (en) | 1993-12-09 | 2000-09-13 | Thomas Jefferson University | Compounds and methods for site-directed mutations in eukaryotic cells |
| US6428771B1 (en) | 1995-05-15 | 2002-08-06 | Pharmaceutical Discovery Corporation | Method for drug delivery to the pulmonary system |
| ES2261195T3 (es) | 1999-04-05 | 2006-11-16 | Mannkind Corporation | Metodo de formacion de particulas finas. |
| ES2569916T3 (es) | 1999-06-29 | 2016-05-13 | Mannkind Corporation | Formulaciones farmacéuticas que comprenden insulina complejada con una dicetopiperazina |
| US8853266B2 (en) | 2001-12-06 | 2014-10-07 | University Of Tennessee Research Foundation | Selective androgen receptor modulators for treating diabetes |
| US20060039985A1 (en) | 2004-04-27 | 2006-02-23 | Bennett David B | Methotrexate compositions |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| CN101014321A (zh) | 2004-08-23 | 2007-08-08 | 曼金德公司 | 5型磷酸二酯酶抑制剂的肺部给予 |
| KR20130066695A (ko) | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| MX373000B (es) | 2005-09-14 | 2020-05-21 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
| EP1986679B1 (en) | 2006-02-22 | 2017-10-25 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| DK2617431T3 (en) * | 2007-01-10 | 2017-07-10 | Purdue Research Foundation | Polypeptide inhibitors of HSP27 kinase and applications therefor |
| WO2009021137A2 (en) * | 2007-08-07 | 2009-02-12 | Purdue Research Foundation | Kinase inhibitors and uses thereof |
| CN102256613B (zh) | 2008-10-20 | 2014-09-10 | 莫伊莱麦屈克斯公司 | 用于治疗或者预防粘连的多肽 |
| EP2378875B1 (en) | 2008-12-10 | 2018-05-30 | Purdue Research Foundation | Cell-permeant peptide-based inhibitor of kinases |
| US9890195B2 (en) | 2009-07-27 | 2018-02-13 | Purdue Research Foundation | MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration |
| US20130115256A1 (en) | 2010-05-24 | 2013-05-09 | Cynthia Lander | Methods for treating or preventing vascular graft failure |
| US10105356B2 (en) * | 2011-01-31 | 2018-10-23 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| US9890200B2 (en) * | 2011-04-12 | 2018-02-13 | Moerae Matrix, Inc. | Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition |
| KR101862291B1 (ko) | 2011-04-12 | 2018-05-29 | 모레 매트릭스 인코포레이티드 | 이상 섬유모세포 증식 및 세포외 기질 침착을 특징으로 하는 질병, 질환, 또는 과정을 예방하거나 치료하기 위한 조성물 및 방법 |
| BR112014030750A2 (pt) | 2012-06-06 | 2017-08-22 | Inst Catalana Recerca Estudis Avancats | Método para diagnóstico, prognóstico e tratamento da metástase do câncer pulmonar |
| US20140072613A1 (en) | 2012-09-10 | 2014-03-13 | Cynthia Lander | Compositions and Methods for Treating Cutaneous Scarring |
-
2016
- 2016-03-10 RU RU2017135072A patent/RU2017135072A/ru not_active Application Discontinuation
- 2016-03-10 US US15/066,976 patent/US9999655B2/en not_active Expired - Fee Related
- 2016-03-10 WO PCT/US2016/021843 patent/WO2016145234A2/en not_active Ceased
- 2016-03-10 MX MX2017011633A patent/MX2017011633A/es unknown
- 2016-03-10 KR KR1020177028070A patent/KR20170125090A/ko not_active Withdrawn
- 2016-03-10 HK HK18109079.5A patent/HK1249433A1/zh unknown
- 2016-03-10 AU AU2016229017A patent/AU2016229017A1/en not_active Abandoned
- 2016-03-10 EP EP16762545.8A patent/EP3268022A4/en not_active Withdrawn
- 2016-03-10 SG SG11201707281QA patent/SG11201707281QA/en unknown
- 2016-03-10 JP JP2017548089A patent/JP2018512401A/ja active Pending
- 2016-03-10 CN CN201680022723.9A patent/CN107921082A/zh active Pending
- 2016-03-10 CA CA2978941A patent/CA2978941A1/en not_active Abandoned
- 2016-03-10 BR BR112017019343A patent/BR112017019343A2/pt not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018512401A5 (https=) | ||
| RU2017135072A (ru) | Применение пептидсодержащих композиций ингибитора mk2 для лечения немелкоклеточного рака легкого | |
| JP6685875B2 (ja) | 治療薬の組み合わせおよび投与の様式ならびに併用療法 | |
| TWI599369B (zh) | 包含阿柏西普(aflibercept)、醛葉酸、5-氟尿嘧啶(5-fu)及伊立替康(irinotecan)(folfiri)之組合物 | |
| Zarogoulidis et al. | Feasibility and effectiveness of inhaled carboplatin in NSCLC patients | |
| JP2022031331A (ja) | 空間配置が変化した組換えインターフェロンを用いる腫瘍治療の方法 | |
| Wang et al. | The impact of previous therapy strategy on the efficiency of anlotinib hydrochloride as a third-line treatment on patients with advanced non-small cell lung cancer (NSCLC): a subgroup analysis of ALTER0303 trial | |
| Fulzele et al. | Inhalation delivery and anti-tumor activity of celecoxib in human orthotopic non-small cell lung cancer xenograft model | |
| Paudel et al. | Targeting lung cancer using advanced drug delivery systems | |
| Chen et al. | Nab-paclitaxel (abraxane)-based chemotherapy to treat elderly patients with advanced non-small-cell lung cancer: a single center, randomized and open-label clinical trial | |
| Kentepozidis et al. | Docetaxel plus cisplatin and bevacizumab for untreated patients with advanced/metastatic non-squamous non-small-cell lung cancer: a multicenter phase II study of the Hellenic Oncology Research Group | |
| Wysocka et al. | Adjuvant, neoadjuvant, and experimental regimens in overcoming pancreatic ductal adenocarcinoma | |
| Brus et al. | Second line therapy for advanced pancreatic adenocarcinoma: where are we and where are we going? | |
| TW202245768A (zh) | 用於治療小細胞肺癌之氧雜雙環庚烷 | |
| Ghassami et al. | Biodistribution, safety and organ toxicity of docetaxel-loaded in HER-2 aptamer conjugated Ecoflex® nanoparticles in a mouse xenograft model of ovarian cancer | |
| Hu et al. | Current status of CPT and its analogues in the treatment of malignancies | |
| JP2021521130A (ja) | 増殖性障害の治療のための投薬レジメン | |
| Zia et al. | Concurrent radiotherapy and chemotherapy with erlotinib followed by maintenance erlotinib in patients with Epidermal Growth Factor Receptor mutation-positive adenocarcinoma lung | |
| Abdel-Ghany et al. | Titanium oxide nanoparticles improve the chemotherapeutic action of erlotinib in liver cancer cells | |
| AU2020356356A1 (en) | Dosing regimens for treatment of patients with locally advanced squamous cell carcinoma | |
| Blais et al. | Sunitinib combined with pemetrexed and carboplatin in patients with advanced solid malignancies—results of a phase I dose-escalation study | |
| Yingchun et al. | Application of nano-drug delivery technology in overcoming drug resistance in lung cancer | |
| Park et al. | Phase II trial of weekly docetaxel and gemcitabine for previously untreated, advanced non-small cell lung cancer | |
| Shin et al. | Prospective phase II trial of a combination of fixed dose rate infusion of gemcitabine with cisplatin and UFT as a first-line treatment in patients with advanced non-small-cell lung carcinoma | |
| Khan et al. | MA01. 09 efficacy and safety of glembatumumab vedotin in patients with advanced or metastatic squamous cell carcinoma of the lung (PrECOG 0504) |