JP2018509909A - 陰イオンチャネルロドプシンの組成物及び使用方法 - Google Patents

陰イオンチャネルロドプシンの組成物及び使用方法 Download PDF

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Publication number
JP2018509909A
JP2018509909A JP2017548954A JP2017548954A JP2018509909A JP 2018509909 A JP2018509909 A JP 2018509909A JP 2017548954 A JP2017548954 A JP 2017548954A JP 2017548954 A JP2017548954 A JP 2017548954A JP 2018509909 A JP2018509909 A JP 2018509909A
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seq
cell
rhodopsin
sequence
nucleic acid
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JP2018509909A5 (enExample
Inventor
ジョン リー スプディック，
ジョン リー スプディック，
エレナ ジー． ゴボルノヴァ，
エレナ ジー． ゴボルノヴァ，
オレグ エー． シネシュチェコフ，
オレグ エー． シネシュチェコフ，
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University of Texas System
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University of Texas System
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Publication of JP2018509909A5 publication Critical patent/JP2018509909A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/405—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2017548954A 2015-03-19 2016-03-18 陰イオンチャネルロドプシンの組成物及び使用方法 Pending JP2018509909A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562135470P 2015-03-19 2015-03-19
US62/135,470 2015-03-19
US201562149812P 2015-04-20 2015-04-20
US62/149,812 2015-04-20
US201562261821P 2015-12-01 2015-12-01
US62/261,821 2015-12-01
PCT/US2016/023095 WO2016149599A1 (en) 2015-03-19 2016-03-18 Compositions and methods for use of anion channel rhodopsins

Publications (2)

Publication Number Publication Date
JP2018509909A true JP2018509909A (ja) 2018-04-12
JP2018509909A5 JP2018509909A5 (enExample) 2019-04-25

Family

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Family Applications (1)

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JP2017548954A Pending JP2018509909A (ja) 2015-03-19 2016-03-18 陰イオンチャネルロドプシンの組成物及び使用方法

Country Status (7)

Country Link
US (1) US10519205B2 (enExample)
EP (1) EP3271376B1 (enExample)
JP (1) JP2018509909A (enExample)
CN (1) CN107531765B (enExample)
AU (1) AU2016232819B2 (enExample)
CA (1) CA2979975A1 (enExample)
WO (1) WO2016149599A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
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JPWO2021193732A1 (enExample) * 2020-03-24 2021-09-30
JP2023047858A (ja) * 2021-09-27 2023-04-06 国立大学法人岩手大学 改変光受容クロライドチャネル

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JP2018509909A (ja) 2015-03-19 2018-04-12 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 陰イオンチャネルロドプシンの組成物及び使用方法
US20190367564A1 (en) * 2016-11-17 2019-12-05 The Board Of Regents Of The University Of Texas System Compositions and methods for use of anion channel rhodopsins
CN111518813B (zh) * 2019-02-03 2023-04-28 武汉纽福斯生物科技有限公司 视紫红质的编码序列、其表达载体构建及其应用
US11598792B2 (en) * 2019-05-09 2023-03-07 Howard Hughes Medical Institute Voltage indicators
US20220056100A1 (en) * 2020-08-20 2022-02-24 Board Of Regents Of The University Of Texas System Compositions and methods for use of red-shifted anion channel rhodopsins

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ACCESSION NO. L1IFZ3, ENTRY VERSION 10: "Uncharacterized protein", DATABASE UNIPROT [ONLINE], vol. [Retrieved on 2019.12.20], JPN6019051656, 4 March 2015 (2015-03-04), ISSN: 0004314776 *
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2021193732A1 (enExample) * 2020-03-24 2021-09-30
WO2021193732A1 (ja) * 2020-03-24 2021-09-30 国立大学法人岩手大学 改変光受容クロライドチャネル
JP7745890B2 (ja) 2020-03-24 2025-09-30 国立大学法人岩手大学 改変光受容クロライドチャネル
JP2023047858A (ja) * 2021-09-27 2023-04-06 国立大学法人岩手大学 改変光受容クロライドチャネル
JP7756391B2 (ja) 2021-09-27 2025-10-20 国立大学法人岩手大学 改変光受容クロライドチャネル

Also Published As

Publication number Publication date
CA2979975A1 (en) 2016-09-22
CN107531765B (zh) 2021-07-16
WO2016149599A1 (en) 2016-09-22
US20180118793A1 (en) 2018-05-03
EP3271376A1 (en) 2018-01-24
CN107531765A (zh) 2018-01-02
EP3271376B1 (en) 2022-05-25
AU2016232819B2 (en) 2021-10-21
US10519205B2 (en) 2019-12-31
AU2016232819A1 (en) 2017-10-05
EP3271376A4 (en) 2018-11-07

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