JP2018502068A5 - - Google Patents

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Publication number
JP2018502068A5
JP2018502068A5 JP2017530141A JP2017530141A JP2018502068A5 JP 2018502068 A5 JP2018502068 A5 JP 2018502068A5 JP 2017530141 A JP2017530141 A JP 2017530141A JP 2017530141 A JP2017530141 A JP 2017530141A JP 2018502068 A5 JP2018502068 A5 JP 2018502068A5
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JP
Japan
Prior art keywords
pharmaceutical composition
fusion protein
condition
high affinity
use according
Prior art date
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Application number
JP2017530141A
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English (en)
Japanese (ja)
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JP2018502068A (ja
JP7095992B2 (ja
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Priority claimed from PCT/US2015/064572 external-priority patent/WO2016094456A1/en
Publication of JP2018502068A publication Critical patent/JP2018502068A/ja
Publication of JP2018502068A5 publication Critical patent/JP2018502068A5/ja
Application granted granted Critical
Publication of JP7095992B2 publication Critical patent/JP7095992B2/ja
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JP2017530141A 2014-12-08 2015-12-08 可溶性ユニバーサルadcc増強合成融合遺伝子およびペプチド技術ならびにその使用 Active JP7095992B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462089097P 2014-12-08 2014-12-08
US62/089,097 2014-12-08
US201562200557P 2015-08-03 2015-08-03
US62/200,557 2015-08-03
PCT/US2015/064572 WO2016094456A1 (en) 2014-12-08 2015-12-08 Soluble universal adcc-enhancing synthetic fusion gene and peptide technology and its use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020198225A Division JP2021035994A (ja) 2014-12-08 2020-11-30 可溶性ユニバーサルadcc増強合成融合遺伝子およびペプチド技術ならびにその使用

Publications (3)

Publication Number Publication Date
JP2018502068A JP2018502068A (ja) 2018-01-25
JP2018502068A5 true JP2018502068A5 (https=) 2018-12-13
JP7095992B2 JP7095992B2 (ja) 2022-07-05

Family

ID=56108081

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017530141A Active JP7095992B2 (ja) 2014-12-08 2015-12-08 可溶性ユニバーサルadcc増強合成融合遺伝子およびペプチド技術ならびにその使用
JP2020198225A Pending JP2021035994A (ja) 2014-12-08 2020-11-30 可溶性ユニバーサルadcc増強合成融合遺伝子およびペプチド技術ならびにその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2020198225A Pending JP2021035994A (ja) 2014-12-08 2020-11-30 可溶性ユニバーサルadcc増強合成融合遺伝子およびペプチド技術ならびにその使用

Country Status (11)

Country Link
US (2) US12247062B2 (https=)
EP (1) EP3230311B1 (https=)
JP (2) JP7095992B2 (https=)
KR (1) KR102654033B1 (https=)
CN (1) CN107108718B (https=)
AU (1) AU2015360642B2 (https=)
CA (1) CA2968987C (https=)
NZ (1) NZ732073A (https=)
RU (1) RU2725807C2 (https=)
SG (1) SG11201704124YA (https=)
WO (1) WO2016094456A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201804945WA (en) 2013-12-12 2018-07-30 Shanghai hengrui pharmaceutical co ltd Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof
KR102654033B1 (ko) 2014-12-08 2024-04-02 1글로브 바이오메디칼 씨오., 엘티디. 가용성 유니버셜 adcc 증강 합성 융합 유전자 및 펩티드 기술 및 그 용도
US12269863B2 (en) 2018-05-23 2025-04-08 Manysmart Therapeutics, Inc. Bispecific T cell engager and uses thereof
WO2020232247A1 (en) 2019-05-14 2020-11-19 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
IL298999A (en) 2020-06-11 2023-02-01 Provention Bio Inc Methods and compositions for the prevention of type 1 diabetes
TW202216174A (zh) * 2020-06-30 2022-05-01 日商蓋亞生物製藥有限公司 使nk細胞與抗體之結合穩定化之方法及其利用
JP2024520444A (ja) 2021-05-24 2024-05-24 プロヴェンション・バイオ・インコーポレイテッド 1型糖尿病を治療するための方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223426A (en) * 1988-12-15 1993-06-29 T Cell Sciences, Inc. Monoclonal antibodies reactive with defined regions of the t-cell antigen receptor
IE920716A1 (en) * 1991-03-07 1992-09-09 Gen Hospital Corp Redirection of cellular immunity by receptor chimeras
EP0826696B1 (de) * 1996-09-03 2002-05-29 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Verwendung bi-und trispezifischer Antikörper zur Induktion einer Tumorimmunität
PT1974747E (pt) * 1998-08-11 2012-09-05 Biogen Idec Inc Terapias de combinação para linfomas de células b compreendendo a administração de anticorpo anti-cd20
IL155812A0 (en) * 2000-12-07 2003-12-23 Lilly Co Eli Glp-1 fusion proteins
WO2002098897A2 (en) * 2001-06-01 2002-12-12 Cornell Research Foundation, Inc. Modified antibodies to prostate-specific membrane antigen and uses thereof
EP1597350B1 (en) * 2003-02-27 2015-04-08 Yeda Research And Development Co., Ltd. Nucleic acid molecules, and compositions containing same useful for treating and detecting influenza virus infection
JP2006526414A (ja) 2003-06-02 2006-11-24 アレクシオン ファーマシューティカルズ, インコーポレイテッド 脱免疫化抗cd3抗体
MXPA06004035A (es) * 2003-10-16 2006-08-31 Micromet Ag Aglutinantes cd3 de-inmunizados multi-especificos.
EP1716178B1 (en) * 2004-02-16 2010-08-11 Micromet AG Less immunogenic binding molecules
US20080003225A1 (en) 2006-06-29 2008-01-03 Henri Vie Method for enhancing the antibody-dependent cellular cytotoxicity (ADCC) and uses of T cells expressing CD16 receptors
AU2008209436A1 (en) * 2007-01-23 2008-07-31 Zymogenetics, Inc. Soluble Fc gamma R1a for reducing inflammation
US8043621B2 (en) * 2007-05-10 2011-10-25 Ramot At Tel Aviv University Ltd. Recombinant fusion protein and polynucleotide construct for immunotoxin production
WO2011085178A1 (en) 2010-01-11 2011-07-14 Trustees Of Dartmouth College Monomeric bi-specific fusion protein
US9505826B2 (en) * 2010-12-22 2016-11-29 Teva Pharmaceuticals Australia Pty Ltd Modified antibody with improved half-life
HK1202587A1 (en) * 2011-12-15 2015-10-02 The Royal Institution For The Advancement Of Learning/Mcgill University Soluble igf receptor fc fusion proteins and uses thereof
MX353382B (es) * 2012-03-01 2018-01-10 Amgen Res Munich Gmbh Moleculas de union polipeptido de larga duracion.
KR102654033B1 (ko) 2014-12-08 2024-04-02 1글로브 바이오메디칼 씨오., 엘티디. 가용성 유니버셜 adcc 증강 합성 융합 유전자 및 펩티드 기술 및 그 용도

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