JP2018203683A - Antiperspirant composition - Google Patents

Abstract

To provide antiperspirant compositions which has no tight feel nor stickiness of the skin after applying an antiperspirant composition, has excellent antiperspirant effect and stability, and can suppress the darkening of armpit while using the antiperspirant composition.SOLUTION: The present invention provides an antiperspirant composition containing (A) at least one antiperspirant component selected from an aluminium compound, a zirconium compound, and a complex thereof; (B) polyoxypropylene stearyl ether with an average addition mole number of propylene oxide of 11 or more to 15 or less; (C) an anti-inflammatory component; (D) at least one selected from trimethylglycine, pyrrolidone carboxylic acid sodium, sorbitol, serine, and glycine; (E1) polyoxyethylene stearylether with an average addition mole number of ethylene oxide of 2 or more to 8 or less; (E2) polyoxyethylene stearylether with an average addition mole number of ethylene oxide of 10 or more to 30 or less; and (F) water.SELECTED DRAWING: None

Description

  The present invention relates to an antiperspirant composition.

  In younger women, armpit skin may become dark due to physical damage caused by armpit hair treatment. Furthermore, by using an antiperspirant on the armpit, the skin of the armpit may be stimulated, and the skin darkening of the armpit may become normal.

  So far, a method for making an armpit using a cosmetic material containing powder has been proposed for the problem of skin darkening (for example, see Patent Document 1). However, in this proposal, the effect of improving the appearance can be obtained by covering the darkening of the armpit with the powder, but the effect of improving the basic darkening cannot be obtained.

  Accordingly, there is a strong demand for the development of an antiperspirant composition that can improve darkening of the armpit while using the antiperspirant.

JP 2000-86446 A

  An object of the present invention is to solve the above-described problems and achieve the following objects. That is, the present invention has no anti-smoothness and stickiness of the skin after application of the antiperspirant composition, is excellent in antiperspirant effect and stability of the preparation, and is darkened while using the antiperspirant composition. An object of the present invention is to provide an antiperspirant composition capable of suppressing the above.

  As a result of intensive studies by the inventor in order to solve the above problems, (A) an antiperspirant component, (B) polyoxypropylene stearyl ether, (C) an anti-inflammatory component, (D) trimethylglycine, pyrrolidone When at least one selected from sodium carboxylate, sorbitol, serine, and glycine, (E) polyoxyethylene stearyl ether, and (F) water are blended, these components work synergistically, and antiperspirant It is known that after applying the agent composition, there is no feeling of skin firmness and skin stickiness, it is excellent in antiperspirant effect and stability of the preparation, and it can suppress darkening of the armpit while using the antiperspirant composition. did.

This invention is based on the said knowledge by this inventor, and as a means for solving the said subject, it is as follows.
<1> (A) at least one antiperspirant component selected from aluminum compounds, zirconium compounds, and complexes thereof;
(B) polyoxypropylene stearyl ether having an average addition mole number of propylene oxide of 11 or more and 15 or less;
(C) an anti-inflammatory component;
(D) at least one selected from trimethylglycine, sodium pyrrolidonecarboxylate, sorbitol, serine, and glycine;
(E1) polyoxyethylene stearyl ether having an average added mole number of ethylene oxide of 2 or more and 8 or less;
(E2) polyoxyethylene stearyl ether having an average added mole number of ethylene oxide of 10 or more and 30 or less;
(F) An antiperspirant composition comprising water.
<2> The antiperspirant composition according to <1>, wherein the component (A) is chlorohydroxyaluminum.
<3> The antiperspirant composition according to any one of <1> to <2>, wherein the component (C) is at least one selected from allantoin and dipotassium glycyrrhizinate.
<4> The content of the component (A) is 7% by mass to 20% by mass,
Content of the said (B) component is 1 mass%-2.5 mass%,
Content of the said (C) component is 0.05 mass%-0.5 mass%,
Content of the said (D) component is 0.5 mass%-2 mass%,
The content of the component (E1) is 1.5% by mass to 2.5% by mass,
The content of the component (E2) is 1.5% by mass to 2.5% by mass,
The antiperspirant composition according to any one of <1> to <3>, wherein the content of the component (F) is 70% by mass to 85% by mass.
<5> Any of <1> to <4>, wherein a mass ratio (E1 / E2) of the content of the component (E1) and the content of the component (E2) is 0.6 to 1.2 An antiperspirant composition according to claim 1.
<6> The antiperspirant composition according to any one of <1> to <5>, which is any one of a roll-on type and a lotion type.

  According to the present invention, it is possible to solve the above-described problems and achieve the above-mentioned object, without the feeling of skin tension and stickiness after application of the antiperspirant composition, the antiperspirant effect and the stability of the preparation. It is possible to provide an antiperspirant composition capable of suppressing darkening of the armpit while using the antiperspirant composition.

(Antiperspirant composition)
The antiperspirant composition of the present invention comprises (A) an antiperspirant component, (B) polyoxypropylene stearyl ether, (C) an anti-inflammatory component, (D) trimethylglycine, sodium pyrrolidonecarboxylate, sorbitol, serine, and glycine. (E1) polyoxyethylene stearyl ether having an average addition mole number of ethylene oxide of 2 to 8 and (E2) polyoxyethylene stearyl having an average addition mole number of ethylene oxide of 10 to 30 It contains ether and (F) water, and further contains other components as necessary.

<(A) Antiperspirant ingredient>
The antiperspirant component of the component (A) is at least one selected from aluminum compounds, zirconium compounds, and complexes thereof.
The antiperspirant component of the component (A) is contained in order to impart an antiperspirant effect.

Examples of the aluminum compound, zirconium compound, and complexes thereof include aluminum chloride, aluminum sulfate, aluminum potassium sulfate, aluminum acetate, chlorohydroxyaluminum, allantochloroxyaluminum, chlorohydroxyaluminum / propylene glycol complex, and chlorohydroxyaluminum. / Zirconium glycine complex. These may be used individually by 1 type and may use 2 or more types together.
Among these, chlorohydroxyaluminum, chlorohydroxyaluminum / propylene glycol complex, and chlorohydroxyaluminum / zirconium / glycine complex are preferable, and chlorohydroxyaluminum is more preferable in that the antiperspirant effect is more excellent.

  There is no restriction | limiting in particular as an antiperspirant component of the said (A) component, What was produced suitably may be used and a commercial item may be used. Examples of the commercially available products include chlorohydroxyaluminum (trade name: chlorohydroxyaluminum, manufactured by Taki Chemical Co., Ltd.), chlorohydroxyaluminum / propylene glycol complex (trade names: REHYDROL II, manufactured by SUMMIT REHIS), and potassium aluminum sulfate. (Trade name: Kari Alum, manufactured by Daimei Chemical Co., Ltd.), aluminum / zirconium glycine complex (trade name: Reach AZO-956G, manufactured by SUMMIT REHIS), and the like.

  The content of the antiperspirant component of the component (A) is from 5% by mass to the total amount of the antiperspirant composition from the viewpoint of antiperspirant effect, lack of feeling of skin firmness, and non-stickiness of the skin. 25 mass% is preferable and 7 mass%-20 mass% are more preferable. If the content is less than 5% by mass, the antiperspirant effect may be insufficient, and if it exceeds 25% by mass, the skin will not feel tight and the skin will not be sticky. There is.

<(B) Polyoxypropylene stearyl ether>
The polyoxypropylene stearyl ether of the component (B) is a polyoxypropylene stearyl ether having an average addition mole number of propylene oxide of 11 or more and 15 or less.
The said (B) component is contained in order to provide the suppression effect of the darkening of an armpit.

  The polyoxypropylene stearyl ether of the component (B) may be used alone or in combination of two or more. Among these, polyoxypropylene stearyl ether having an average addition mole number of propylene oxide of 15 is preferable from the viewpoint of suppression of darkening of armpit and stability of the preparation. In addition, about the polyoxypropylene stearyl ether whose average addition mole number of propylene oxide is less than 11 or more than 15, there is no commercial item which can be utilized.

  There is no restriction | limiting in particular as polyoxypropylene stearyl ether of the said (B) component, What was produced suitably may be used and a commercial item may be used. Examples of the commercially available products include polyoxypropylene stearyl ether (trade name: TEGOSOFT E, manufactured by Evonik) having an average addition mole number of propylene oxide of 15 and polyoxypropylene stearyl ether having an average addition mole number of propylene oxide of 11. (Trade name: TEGOSOFT APS, manufactured by Evonik). These may be used individually by 1 type and may use 2 or more types together.

  The content of the component (B) is 0.5% by mass to 3% with respect to the total amount of the antiperspirant composition, from the viewpoint of suppressing the darkening of the armpit, non-stickiness of the skin, and stability of the preparation. % By mass is preferable, and 1% by mass to 2.5% by mass is more preferable. When the content is less than 0.5% by mass, the effect of suppressing the darkening of the armpit and the stability of the preparation may be insufficient. When the content exceeds 3% by mass, the skin is not sticky, and The stability of the formulation may be insufficient.

<(C) Anti-inflammatory component>
The anti-inflammatory component of the component (C) is contained in order to impart an effect of suppressing darkening of the armpit.

Examples of the anti-inflammatory component (C) include allantoin and dipotassium glycyrrhizinate. These may be used alone or in combination of two or more. Among these, allantoin is preferable.
Examples of the commercially available anti-inflammatory component (C) include allantoin (trade name: Lonacare Allantoin, manufactured by MERCK), dipotassium glycyrrhizinate (trade name: dipotassium glycyrrhizinate, manufactured by Maruzen Pharmaceutical Co., Ltd.), and the like. It is done.

  The content of the component (C) is preferably 0.03% by mass to 1% by mass with respect to the total amount of the antiperspirant composition, from the viewpoint of suppressing the darkening of armpits and the stability of the preparation, 05 mass%-0.5 mass% is more preferable. When the content is less than 0.03% by mass, the effect of suppressing darkening of the armpit may be insufficient, and when it exceeds 1% by mass, the stability of the preparation may be insufficient.

<(D) At least one selected from trimethylglycine, sodium pyrrolidonecarboxylate, sorbitol, serine, and glycine>
The component (D), at least one selected from trimethyl glycine, sodium pyrrolidonecarboxylate, sorbitol, serine, and glycine, is contained for imparting the effect of suppressing darkening of the armpit.

  The component (D) may be used alone or in combination of two or more. Among these, it is preferable to use all five components of trimethylglycine, sodium pyrrolidonecarboxylate, sorbitol, serine, and glycine in combination from the viewpoint of suppressing the darkening of the armpit.

  Examples of commercially available products of the component (D) include trimethylglycine (trade name: Amino Coat, manufactured by Asahi Kasei Finechem Co., Ltd.), sodium pyrrolidone carboxylate (trade name: AJIDEW NL-50, manufactured by Ajinomoto Co., Inc.), sorbitol ( Product name: Sorbitol TBS, manufactured by Food Products Science Co., Ltd., Serine (Product name: L-Serine, manufactured by Wako Pure Chemical Industries, Ltd.), Glycine (Product name: Glycine, manufactured by Wako Pure Chemical Industries, Ltd.), 5 The thing containing all the components (brand name: PRODEW400, Ajinomoto Healthy Supply Co., Ltd.) etc. are mentioned.

  The content of the component (D) is preferably 0.3% by mass to 3% by mass with respect to the total amount of the antiperspirant composition from the viewpoint of suppressing the darkening of the armpit and the non-stickiness of the skin. More preferably, the content is 5% by mass to 2% by mass. When the content is less than 0.3% by mass, the effect of suppressing the darkening of the armpit may be insufficient, and when it exceeds 3% by mass, the non-stickiness of the skin may be insufficient. .

<(E) Polyoxyethylene stearyl ether>
The polyoxyethylene stearyl ether of the component (E) is (E1) polyoxyethylene stearyl ether having an average addition mole number of ethylene oxide of 2 to 8, and (E2) an average addition mole number of ethylene oxide of 10 to 30. Contains the following polyoxyethylene stearyl ether.
The component (E) is contained in order to improve the stability of the preparation.

The average addition mole number of polyoxyethylene stearyl ether having an average addition mole number of ethylene oxide of (E1) component of 2 or more and 8 or less is preferably 2 or more and less than 5 from the viewpoint of the stability of the preparation. When the average added mole number exceeds 8, the stability of the preparation may be insufficient.
In addition, about the polyoxyethylene stearyl ether whose average added mole number of ethylene oxide is less than 2, there exists no commercial item which can be utilized.

  The average addition mole number of polyoxyethylene stearyl ether having an average addition mole number of ethylene oxide of the component (E2) of 10 or more and 30 or less is 15 or more and 26 from the viewpoint of the stability of the preparation and the non-stickiness of the skin. Less than is preferable. When the average added mole number is less than 10, the stability of the preparation may be insufficient, and when the average added mole number exceeds 30, the stability of the preparation and the non-stickiness of the skin are insufficient. It may become.

  Examples of commercially available products of the component (E1) include steareth-2 (trade name: EMALEX 602) and steareth-3 (trade name: trade names: ethylene oxide having an average added mole number of 2, 3, 5, and 8, respectively. EMALEX 603), Steareth-5 (trade name: EMALEX 605), Steareth-8 (trade name: EMALEX 608) (all manufactured by Nippon Emulsion Co., Ltd.), and the like.

  Examples of commercially available products of the component (E2) include steareth-11 (trade name: EMALEX 611) and steareth-15, in which the average added moles of ethylene oxide are 11, 15, 16, 20, 25, and 30, respectively. (Trade name: EMALEX 615), steareth-16 (trade name: EMALEX 616), steareth-20 (trade name: EMALEX 620), steareth-25 (trade name: EMALEX 625), steareth-30 (trade name: EMALEX 630) (both Nippon Emulsion Co., Ltd.).

  The content of the component (E1) is preferably 1% by mass to 3% by mass, and 1.5% by mass with respect to the total amount of the antiperspirant composition, from the viewpoint of the stability of the preparation and the non-stickiness of the skin. % To 2.5% by mass is more preferable. When the content is less than 1% by mass, the stability of the preparation may be insufficient, and when it exceeds 3% by mass, the non-stickiness of the skin may be insufficient.

  The content of the component (E2) is preferably 1% by mass to 3% by mass, and 1.5% by mass with respect to the total amount of the antiperspirant composition, from the viewpoint of the stability of the preparation and the non-stickiness of the skin. % To 2.5% by mass is more preferable. When the content is less than 1% by mass, the stability of the preparation may be insufficient, and when it exceeds 3% by mass, the non-stickiness of the skin may be insufficient.

  The mass ratio (E1 / E2) between the content of the component (E1) and the content of the component (E2) is preferably 0.4 to 1.5 from the viewpoint of the stability of the formulation, 0.6 -1.2 is more preferable. When the mass ratio is less than 0.4 or exceeds 1.5, the stability of the preparation may be insufficient.

<(F) Water>
The component (F) water is contained in order to impart stability of the preparation.
The water content of the component (F) is preferably 65% by mass to 90% by mass, and 70% by mass with respect to the total amount of the antiperspirant composition, in terms of the stability of the preparation and the non-stickiness of the skin. -85 mass% is more preferable. When the content is less than 65% by mass, the stability of the preparation may be insufficient, and when it exceeds 90% by mass, the non-stickiness of the skin may be insufficient.
Here, the content of water of the component (F) is a total content including water brought in from these components when the components (A) to (E) and other components are blended. .

<Other ingredients>
In addition to the components (A) to (F), the antiperspirant composition of the present invention is usually blended in the antiperspirant composition according to the dosage form, as long as the effects of the present invention are not impaired. Other ingredients can be added.
The other component is not particularly limited and may be appropriately selected depending on the intended purpose. Examples thereof include oil and fat compounds, wax compounds, silicone compounds, hydrocarbon oils, higher fatty acids, higher alcohols, the component (B) and Surfactants other than the component (E), polymers, antioxidants, dyes, emulsion stabilizers, regulators, preservatives, ultraviolet absorbers, chelating agents, moisturizers, thickeners, cooling agents, bactericides, Examples include amino acids other than the component (D), vitamins, fragrances, and various plant extracts.
In addition, there is no restriction | limiting in particular as content of the said other component, According to the objective, it can select suitably in the range which does not inhibit the effect of this invention.

-PH-
The pH at 25 ° C. of the antiperspirant composition is preferably 3 to 4.5 from the viewpoint of antiperspirant effect, lack of skin irritation, and stability of the preparation. When the pH is less than 3, the antiperspirant effect may be insufficient, and when it exceeds 4.5, the stability of the preparation may be insufficient.

-Viscosity-
The viscosity of the antiperspirant composition is not particularly limited and may be appropriately selected depending on the intended purpose. From the viewpoint of the stability of the preparation and the non-stickiness of the skin, 1 mPa · s at 25 ° C. ˜3,000 mPa · s is preferable, and 5 mPa · s to 1,600 mPa · s is more preferable. When the viscosity is less than 1 mPa · s, the stability of the preparation may be insufficient, and when it exceeds 3,000 mPa · s, the non-stickiness of the skin may be insufficient.
The viscosity is, for example, No. 1 at 25 ° C. using a BL type viscometer. 1-4 rotors can be used, and measurement can be performed at 60 rpm for 1 minute.

-Manufacturing method-
There is no restriction | limiting in particular as a manufacturing method of the antiperspirant composition of this invention, According to the objective, it can select suitably, It can prepare according to the dosage form. For example, the emulsion is obtained by mixing the oil phase containing the component (B) and the component (E) and the aqueous phase containing the component (F) under temperature conditions equal to or higher than the melting point of the component (E). It can manufacture by adding and mixing the said (A) component, the said (C) component, and the said (D) component to the obtained emulsion as needed after that.
There is no restriction | limiting in particular as an apparatus which prepares the said antiperspirant composition, According to the objective, it can select suitably, For example, it equips with the several stirring blade (propeller, turbine, disper, etc.) which can be mixed with shearing. And a stirrer. In addition, as said (A)-said (F) component and said other component, in preparing an antiperspirant composition, you may use each independently, respectively, and the mixture containing 2 or more types of components You may use in the state.

-Dosage form-
The dosage form of the antiperspirant composition is not particularly limited, and examples thereof include a semi-solid type, a gel type, and a liquid type. Among these, gel-type and liquid-type are preferable because it is effective for expression of the effect of being applied to the skin in a state dissolved in moisture, can be applied with high adhesion, and can exhibit a high antiperspirant effect. A type is more preferable.
Examples of the semi-solid type include a cream type.
Examples of the gel type include a gel type.
Examples of the liquid type include a roll-on type, a lotion type, and a mist type. Among these, the lotion type and the roll-on type are preferable from the viewpoint of the antiperspirant effect.

When the antiperspirant composition is a roll-on type, an antiperspirant product comprising the antiperspirant composition and a roll-on container having an application ball and filled with the antiperspirant composition may be used. preferable. The roll-on type preparation is housed in a known roll-on container, a part of the roll-on container is exposed, and the antiperspirant composition is attached to the application ball held by a holder in a rotatable manner. At the time of use, the application balls can be applied to the skin.
Moreover, the gel formulation which fills the said antiperspirant composition in a bottle container, and apply | coats as it is using a container; The gel formulation and lotion formulation which apply | coat using a fingertip or a hand can also be used suitably.

-Container-
Examples of the container include a roll-on container, a gel bottle container, a lotion bottle container, and a mist trigger spray container. Among these, the roll-on container is preferable from the viewpoint of the antiperspirant effect.
The roll-on container can be suitably used in that the antiperspirant composition can be applied to the skin with high adhesion, and an antiperspirant effect can be exhibited. The roll-on container is not particularly limited as long as it can be filled with the antiperspirant composition, and can be appropriately selected according to the purpose. For example, those described in JP-A-2005-186997 Is mentioned.

  Examples of the roll-on container include a bottle (material: HDPE natural, full capacity: about 56 mL, trunk diameter: about 33 mm, height: about 87 mm, manufactured by Yoshino Kogyo Co., Ltd.), ring (material: HDPE natural, Outer diameter: about 26 mm, height: about 18 mm, manufactured by Yoshino Kogyo Co., Ltd.), balls (material: PP white, diameter: about 20 mm, manufactured by Yoshino Kogyo Co., Ltd.), etc. can be used.

  As the bottle container for the lotion, for example, bottle (trade name: TOMIII-50, material: HDPE natural, full capacity: about 34 mL, trunk diameter: about 42 mm × 29 mm (oval), height: about 88 mm, Takemoto (Made by Container Co., Ltd.), inner plug (product name: TO cap nozzle A, material: PE natural, outer diameter: about 12 mm, height: about 13 mm, made by Takemoto Container Co., Ltd.), cap (product name: TOMIII cap, Material: PP white, outer diameter: about 37 mm × 25 mm (oval), height: about 24 mm, manufactured by Takemoto Container Co., Ltd., etc. can be used.

-Application-
The antiperspirant composition of the present invention has no feeling of skin tension and skin stickiness after application of the antiperspirant composition, is excellent in antiperspirant effect and stability of the preparation, and uses the antiperspirant composition. Can be applied to cosmetics, pharmaceuticals, quasi-drugs, etc., and can be suitably used for antiperspirants, deodorants, antiperspirants and deodorants. It is.

  EXAMPLES The present invention will be specifically described below with reference to examples of the present invention, but the present invention is not limited to these examples.

(Examples 1-46 and Comparative Examples 1-10)
Antiperspirant compositions of Examples 1 to 46 and Comparative Examples 1 to 10 having the compositions shown in Tables 1 to 10 below were prepared by a conventional method.
40 mL of each obtained antiperspirant composition was filled in a roll-on container having the following specifications to obtain a roll-on type antiperspirant composition.

<Roll-on container>
<< Bottle >>
-Yoshino Kogyo Co., Ltd. Material: HDPE Natural, Full capacity: approx. 56 mL, trunk diameter: approx. 33 mm, height: approx. 87 mm
<< Ring >>
・ Yoshino Kogyo Co., Ltd. Material: LLDPE Natural, outer diameter: approx. 26mm, height: approx. 18mm
<< ball >>
・ Yoshino Kogyo Co., Ltd. Material: PP White, Diameter: About 20mm

  Next, for each of the roll-on type antiperspirant compositions obtained, the antiperspirant effect, the suppression effect of the darkening of the armpit, the lack of skin firmness, the non-stickiness of the skin, and the formulation Stability was evaluated. The results are shown in Tables 1-10.

[Antiperspirant effect]
<Evaluation method>
For 20 professional panels, 0.5g of antiperspirant composition was applied to one armpit and exercised by a fitness bike (trade name: FB-300HP, manufactured by Remark) in an environment of 38 ° C and 40% relative humidity. I went for 15 minutes. Then, the amount of sweating of the axilla (sample application part) to which the sample was applied using a sweat meter (trade name: SKN-2000, manufactured by Nishizawa Electric Instruments Co., Ltd.) and the axilla to which the sample was not applied (sample non-application part) The antiperspirant rate was determined from the following formula. The average value of 20 professional panels was calculated, and the “antiperspirant effect” was evaluated based on the following evaluation criteria.

<Evaluation criteria>
◎: Average value of antiperspirant rate is 56% or more and 100% or less ◎: Average value of antiperspirant rate is 46% or more and less than 56% ○: Average value of antiperspirant rate is 36% or more and less than 46% △: Antiperspirant Average value of rate is 26% or more and less than 36% ×: Average value of antiperspirant rate is 0% or more and less than 26%

[No skin tightness]
<Evaluation method>
According to the following evaluation criteria, the number of respondents who responded that there was no feeling of skin tightness after applying 0.5g of each antiperspirant composition to the axilla for 20 expert panels and drying it. Evaluation of “no skin tension” after application.
<Evaluation criteria>
◎◎: 19 to 20 out of 20 professional panels responded that there was no feeling of skin ◎: 16 to 18 out of 20 professional panels responded that there was no feeling of skin ○: Expert 11 to 15 out of 20 panelists responded that there was no skin tightness △: 6 to 10 out of 20 professional panelists responded that there was no skin tightness ×: out of 20 professional panelists Less than 5 respondents said they did not feel any skin tightness

[No skin stickiness]
<Evaluation method>
Based on the following evaluation criteria, the number of respondents who answered that there were no stickiness of the skin after applying 0.5g of each antiperspirant composition to the axilla for 20 specialist panels and drying it. The “non-stickiness of the skin” after application was evaluated.
<Evaluation criteria>
◎◎: 19 to 20 out of 20 professional panels responded that there was no skin stickiness ◎: 16 to 18 out of 20 professional panels responded that there was no skin stickiness ○: Expert 11 to 15 out of 20 panelists responded that there was no skin stickiness △: 6 to 10 out of 20 professional panelists responded that there was no skin stickiness ×: out of 20 professional panelists Less than 5 respondents said there was no skin stickiness

[Inhibition of darkening of armpit]
<Evaluation method>
To 20 specialist panels with dark skin on the axilla skin, 0.5 g of each antiperspirant composition was applied to the axilla twice a day in the morning and evening. Similarly, after one week of continuous application, the “effect of suppressing darkening of the armpit” was evaluated based on the following evaluation criteria.
<Evaluation criteria>
◎◎: 19 to 20 out of 20 professional panels responded that the darkness of the armpit has been reduced ◎: 16 to 18 out of 20 professional panels responded that the darkness of the armpit has been reduced ○: Expert 11 to 15 of the 20 panelists answered that the darkness of the armpit had been reduced. △: 6 to 10 of the 20 professional panelists responded that the darkness of the armpit had been reduced. Less than 5 responded that the darkness of the armpit has been reduced

[Stability of formulation (freezing and restoring stability)]
<Evaluation method>
A soft transparent glass bottle (product name: SV-50A, manufactured by Nidec Rika Glass Co., Ltd.) having a capacity of 50 g is filled with 40 g of each prepared antiperspirant composition, stored at −20 ° C. for 1 day and completely frozen. The mixture was allowed to stand at room temperature for 1 day and naturally thawed. “Stability of the preparation” as freeze / restoration stability after repeating this operation 5 times was evaluated based on the following evaluation criteria.
<Evaluation criteria>
◎◎: No water separation or separation is observed ◎: Slight water separation is observed, but no separation is observed ○: Water separation is observed, but no separation is observed △: Very little separation is observed ×: Separation allowed

(Example 47)
An antiperspirant composition having the composition shown in Table 11 below was prepared by a conventional method, and 40 mL of the obtained antiperspirant composition was filled in a lotion type container having the following specifications. The same evaluation as that of the antiperspirant composition was performed. The results are also shown in Table 11.

<Lotion: Bottle container>
Filling volume: 40mL
<< Bottle >>
-Takemoto Container Co., Ltd .: TOMIII-50
Material: HDPE Natural, full capacity: approx. 34 mL, trunk diameter: approx. 42 mm x 29 mm (oval), height: approx. 88 mm
<< Inner plug >>
-Takemoto Container Co., Ltd .: TO cap nozzle A
Material: PE Natural, outer diameter: about 12mm, height: about 13mm
<< cap >>
-Takemoto Container Co., Ltd .: TOMIII cap Material: PP white, outer diameter: about 37mm x 25mm (oval), height: about 24mm

Details of each component of Examples and Comparative Examples are as described in Table 12 below.
In Examples and Comparative Examples including all five components of component (D) and all common components, product name: PRODEW400 (manufactured by Ajinomoto Healthy Supply Co., Ltd.) was used as including all these components. .

  The antiperspirant composition of the present invention has no feeling of skin tension and skin stickiness after application of the antiperspirant composition, is excellent in antiperspirant effect and stability of the preparation, and uses the antiperspirant composition. Can be applied to cosmetics, pharmaceuticals, quasi-drugs, etc., and is suitable for use as antiperspirants, deodorants, antiperspirants, deodorants, etc. Is possible.

Claims (6)

(A) at least one antiperspirant component selected from aluminum compounds, zirconium compounds, and complexes thereof;
(B) polyoxypropylene stearyl ether having an average addition mole number of propylene oxide of 11 or more and 15 or less;
(C) an anti-inflammatory component;
(D) at least one selected from trimethylglycine, sodium pyrrolidonecarboxylate, sorbitol, serine, and glycine;
(E1) polyoxyethylene stearyl ether having an average added mole number of ethylene oxide of 2 or more and 8 or less;
(E2) polyoxyethylene stearyl ether having an average added mole number of ethylene oxide of 10 or more and 30 or less;
(F) An antiperspirant composition comprising water.   The antiperspirant composition according to claim 1, wherein the component (A) is chlorohydroxyaluminum.   The antiperspirant composition according to claim 1, wherein the component (C) is at least one selected from allantoin and dipotassium glycyrrhizinate. The content of the component (A) is 7% by mass to 20% by mass,
Content of the said (B) component is 1 mass%-2.5 mass%,
Content of the said (C) component is 0.05 mass%-0.5 mass%,
Content of the said (D) component is 0.5 mass%-2 mass%,
The content of the component (E1) is 1.5% by mass to 2.5% by mass,
The content of the component (E2) is 1.5% by mass to 2.5% by mass,
The antiperspirant composition according to any one of claims 1 to 3, wherein the content of the component (F) is 70% by mass to 85% by mass.   The antiperspirant according to any one of claims 1 to 4, wherein a mass ratio (E1 / E2) of the content of the component (E1) and the content of the component (E2) is 0.6 to 1.2. Agent composition.   The antiperspirant composition according to any one of claims 1 to 5, which is one of a roll-on type and a lotion type.