JP2018203365A - Lid material for blister pack - Google Patents

Abstract

To provide a lid material for blister pack that has a desired absorption function, and can be easily opened without breaking of an absorption layer.SOLUTION: A lid material for blister pack 10 has a substrate layer 18, an absorption layer 12, and an easily peelable resin layer 14 in the stated order. The absorption layer contains an absorption layer resin, and an absorbent. The easily peelable resin layer contains an easily peelable resin.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a cover material for blister packs.

  Conventionally, blister packs have been used as packaging containers for solid preparations such as tablets and capsules containing drugs. In this blister pack, a blister container sheet is formed by forming a recess called a pocket in a blister container sheet composed of a resin sheet or the like, the contents are put in the pocket, and the lid is sealed by heat sealing or the like. It can be formed by bonding.

  The blister container is a blister pack containing contents in which a preparation or the like is enclosed by heat-sealing a lid material at a hem portion spreading around the blister container in a state where the preparation or the like is accommodated inside the pocket. If the blister container and / or the lid used for packaging is transparent, the preparation enclosed therein can be easily visually confirmed. As a means for taking out the contents from the blister pack, the pocket of the blister container is mainly pressed and deformed from the outside to the lid material side, the lid material is broken with the contents, and the contents are taken out (push-through). ing.

  There are various active ingredients of the preparation enclosed in the blister pack, and among them, there are active ingredients with low moisture resistance and active ingredients with strong odor. In view of this, a means has been proposed in which a blister pack after molding has an absorption function by forming an absorption layer that absorbs moisture, odor, and the like in advance in the blister container sheet or lid.

  Patent Document 1 discloses a technique for protecting a moisture-sensitive product from moisture by laminating a plastic material layer containing a desiccant that absorbs moisture on a lid material for blister packs.

Special table 2012-520802 gazette

  In order to be able to take out the contents from the blister pack using the blister pack lid material of Patent Document 1 by push-through that breaks the lid material, the thickness of the plastic material layer containing the desiccant is reduced. Since it needs to be controlled, the easy-openability of the lid material and the desired absorption performance may not be compatible.

  Moreover, when trying to push through the lid material for blister packs of Patent Document 1 as in the conventional case, the plastic material layer will be broken, and as a result, the desiccant contained in the plastic material layer contacts the contents. There was something to do.

  Accordingly, there is a need to provide a blister pack lid that has the desired absorption performance and can be easily opened without breaking the absorbent layer.

As a result of intensive studies, the present inventors have found that the above problems can be solved by the following means, and have completed the present invention. That is, the present invention is as follows:
<1> A substrate layer, an absorbent layer, and an easily peelable layer are provided in this order,
The absorption layer contains a resin composition for an absorption layer and an absorbent,
The easily peelable layer contains an easily peelable resin composition,
Blister pack lid.
<2> The above-mentioned easily peelable layer is fused to a blister container having a pocket, thereby corresponding to the joint part where the above blister container and the above easily peelable layer are joined, and the above-mentioned pocket of the above blister container. And forming a non-joined part where the blister container and the easily peelable layer are not joined, and peeling off the lid,
(I) The blister container can be interfacially peeled from the easily peelable layer, or (ii) In the joint part, the easily peelable layer follows the blister container and the non-joined part. In, the easily peelable layer can follow the absorption layer,
The lid material according to <1> above.
<3> The lid according to <1> or <2>, wherein the absorbent layer and the easily peelable layer are fused to each other.
<4> The structure according to any one of <1> to <3>, further including a protective layer fused to the absorbent layer between the base material layer and the absorbent layer. Cover material.
<5> The resin composition for an absorbent layer contains a polyethylene resin and an acid-modified polyolefin, and the easily peelable resin composition is a polypropylene resin.
The lid | cover material as described in any one of said <1>-<4> term.
<6> A protective layer fused to the absorbent layer between the base material layer and the absorbent layer is further provided, and the protective layer is made of polyethylene resin, block polypropylene, and random polypropylene. Composed of at least one selected from the group consisting of:
The lid material according to <5> above.
<7> A blister pack having a content, a blister container, and a lid,
The blister container has a pocket,
The lid material includes a base material layer, an absorption layer, and an easily peelable layer,
The absorption layer contains a resin composition for an absorption layer and an absorbent,
The easily peelable layer contains an easily peelable resin composition, and the easily peelable layer is fused to the blister container, whereby the contents are accommodated in the pockets, And a non-joint part corresponding to the pocket of the blister container and not joined to the blister container and the easily peelable layer. And when the lid is peeled off,
(I) The blister container can be interfacially peeled from the easily peelable layer, or (ii) In the joint part, the easily peelable layer follows the blister container and the non-joined part. In, the easily peelable layer can follow the absorption layer,
Blister pack with contents.
<8> The resin composition constituting the surface of the blister container joined to the easily peelable layer and the easily peelable resin composition are both polypropylene resins,
The absorbent layer resin composition contains a polyethylene resin and an acid-modified polyolefin,
The blister pack containing the contents according to <7> above.
<9> Blister pack lid material;
A combination with a blister container having a pocket,
The lid material includes a base material layer, an absorption layer, and an easily peelable resin layer,
The absorbent layer contains an absorbent layer resin composition and an absorbent, and the easily peelable resin layer contains an easily peelable resin composition,
The blister container corresponds to the joint where the blister container and the easy peel layer are joined by fusing the easy peel layer to the blister container, and the pocket of the blister container. And the non-bonding part where the easily peelable layer is not bonded, and when the lid is peeled off,
(I) The blister container can be interfacially peeled from the easily peelable layer, or (ii) In the joint part, the easily peelable layer follows the blister container and the non-joined part. In, the easily peelable layer can follow the absorption layer,
combination.

  ADVANTAGE OF THE INVENTION According to this invention, it can provide the cover material for blister packs which has a desired absorption function and can be easily opened, without breaking an absorption layer.

FIG. 1 is a diagram showing a layer structure of an embodiment of the blister pack of the present invention. FIG. 2 is a view showing a peeling mechanism of one embodiment of the blister pack of the present invention. FIG. 3 is a view showing a peeling mechanism of the following embodiment (ii) of the blister pack of the present invention. FIG. 4 is an explanatory diagram of a peel test. FIG. 5 is an explanatory diagram of a peel test.

《Blister for Blister Pack》
As shown in FIG. 1, the lid | cover material (10) for blister packs of this invention is equipped with the base material layer (18), the absorption layer (12), and the easily peelable layer (14), For blister packs. It is a cover material (10). The absorption layer (12) contains the resin composition for absorption layers and an absorbent. The easily peelable layer (14) contains an easily peelable resin composition. Moreover, the lid | cover material for blister packs of this invention may comprise the optional protective layer (16).

  Here, within the context of the present invention, the “easy peelable layer” means that the blister container having pockets is bonded to the easy peelable layer side of the lid, and then the easy peelable layer is cohesively broken. And / or a layer that can be opened by separating the base layer and the absorbent layer by interfacially peeling the blister container from the easily peelable layer and / or delamination of the absorbent layer. is there.

  More specifically, the easily peelable layer is formed by interfacially peeling the blister container (20) from the easily peelable layer (14) as shown in FIG. 2 (a), as shown in FIG. 2 (b). A layer capable of delamination of the absorbent layer (12) from the easily peelable layer (14) and / or cohesive failure of the easily peelable layer (14) as shown in FIG. 2 (c). is there. In the embodiment shown in FIGS. 2B and 2C, for example, the pocket (22) is then deformed by pressing the pocket (22) toward the lid (10) and the contents (30) are pushed out. The content (30) can be removed without causing the components to adhere to the content (30).

  Even when the thickness of the absorbent layer is designed to ensure the desired absorption performance, the lid material for blister packs of the present invention can be easily opened without breaking the absorbent layer due to the presence of the easily peelable layer. be able to.

In a preferred embodiment of the present invention, the easily peelable layer is fused to a blister container having a pocket, thereby corresponding to the joint where the blister container and the easily peelable layer are joined, and the pocket of the blister container. And when the blister container and the easily peelable layer form a non-joined part that is not joined, and the lid material is peeled off,
(I) As mentioned with reference to FIG. 2 (a), the blister container can be interfacely peeled from the easily peelable layer, or (ii) At the joint, the easily peelable layer follows the blister container. And an easily peelable layer can follow an absorption layer in a non-joining part.
The embodiment (ii) will be described with reference to FIG.

  As shown in FIG. 3 (a), a blister container (20) having a pocket (22) is joined to a lid (10), thereby joining the blister container (20) and the easily peelable layer (14). Corresponding to the joint (14a) and the pocket (22) of the blister container (20), and the blister container (20) and the easily peelable layer (14) are not joined. When the cover material (10) is peeled off, the absorbent layer (12) peels from the easily peelable layer (14) in the region corresponding to the joint (14a).

  In order to realize this delamination, a non-joining part (14b ') may be further provided between the blister container and the easily peelable layer, and this may be used as a peeling trigger. In the case of this aspect, when the peeled surface reaches the boundary between the non-joining part (14b ′) and the joining part (14a), as shown in FIG. 3B, the easily peelable layer (14) is formed. A fracture portion (142 ′) is formed, and the absorbent layer (12) is delaminated from the easily peelable layer (14) in a region corresponding to the joint portion (14a).

  When the absorbent layer (12) is further delaminated, the peeling surface eventually reaches the boundary between the bonded portion (14a) and the non-bonded portion (14b) as shown in FIG. As shown to c), a fracture | rupture part (142) is formed in an easily peelable layer (14), and an easily peelable layer (14) follows an absorption layer (12) in a non-joining part (14b).

  When the peeling is further advanced, as shown in FIG. 3 (d), the fracture portion (142) reaches the opposite edge of the pocket (22), and as shown in FIG. 3 (e), the easily peelable layer ( 14) is divided corresponding to the pocket (22).

Such peeling behavior is between the adhesive strength A between the blister container and the easily peelable layer, the adhesive strength B between the absorbent layer and the easily peelable layer, and the breaking strength C of the easily peelable layer. Occurs when the following conditions are met:
A>B> C.

  In order to satisfy the above relationship, the resin composition constituting the surface to be bonded to the easily peelable layer of the blister container and the easily peelable resin composition both contain a polypropylene resin and absorb The layer resin composition preferably contains a polyethylene resin and an acid-modified polyolefin.

  According to the embodiment of (ii) above, even when the blister container and the easily peelable layer are joined by fusion, it is stable without depending on conditions such as the temperature, pressure, and time of thermal fusion. The lid material for blister packs can be peeled with the strength obtained.

  The absorbent layer and the easily peelable layer are preferably fused together from the viewpoint of securing the absorbent performance of the absorbent layer.

  Below, each component of this invention is demonstrated.

<Base material layer>
The base material layer may be composed of only the barrier layer or the resin layer, or may be composed of the barrier layer and the resin layer.

{Barrier layer}
As the barrier layer, a material capable of suppressing moisture, organic gas, and inorganic gas from the outside from being transmitted to the absorption layer can be used. Examples of the barrier layer include, but are not limited to, metal foils such as aluminum foil or aluminum alloy, aluminum vapor deposition films, silica vapor deposition films, alumina vapor deposition films, or inorganic vapor deposition films such as silica / alumina binary vapor deposition films. Alternatively, an organic coating film such as a polyvinylidene chloride coating film or a polyvinylidene fluoride coating film can be used. In particular, an aluminum foil is preferably used as the barrier layer from the viewpoint of making it easy to achieve both barrier properties and handleability as a lid material.

  The thickness of the barrier layer is preferably 7 μm or more, 10 μm or more, or 15 μm or more from the viewpoint of ensuring strength and barrier properties, and is 45 μm or less, 40 μm or less, or 35 μm or less as a lid material. It is preferable from the viewpoint of improving the handleability.

{Resin layer}
As the resin layer, a thermoplastic resin excellent in impact resistance, wear resistance, etc., for example, polyolefin, vinyl polymer, polyester, polyamide, etc. can be used alone or in combination of two or more kinds in multiple layers. . This resin layer may be a stretched film or an unstretched film. The barrier layer can be protected by this resin layer.

  Examples of the polyolefin include polyethylene resins and polypropylene resins.

  In the present specification, the polyethylene-based resin is a resin containing a repeating unit of an ethylene group in the polymer main chain of more than 50 mol%, 60 mol% or more, 70 mol% or more, or 80 mol% or more. Polyethylene (LDPE), linear low density polyethylene (LLDPE), medium density polyethylene (MDPE), high density polyethylene (HDPE), ethylene-acrylic acid copolymer (EAA), ethylene-methacrylic acid copolymer (EMAA) , An ethylene-ethyl acrylate copolymer (EEA), an ethylene-methyl acrylate copolymer (EMA), an ethylene vinyl acetate copolymer (EVA), and derivatives thereof, and mixtures thereof.

  In this specification, the polypropylene resin is a resin containing propylene group repeating units in the polymer main chain of more than 50 mol%, 60 mol% or more, 70 mol% or more, or 80 mol% or more, for example, polypropylene (PP) Examples include homopolymers, random polypropylene (random PP), block polypropylene (block PP), chlorinated polypropylene, acid-modified polypropylene, and derivatives thereof, and mixtures thereof.

  Examples of the vinyl polymer include PVC (polyvinyl chloride), PVDC (polyvinylidene chloride), polychlorotrifluoroethylene, polytetrafluoroethylene, and PAN (polyacrylonitrile).

  Examples of the polyester include PET (polyethylene terephthalate) and polybutylene terephthalate.

  Examples of the polyamide include nylon such as nylon (registered trademark) 6 and nylon MXD6.

  The thickness of the resin layer is preferably 7 μm or more, 10 μm or more, or 15 μm or more from the viewpoint of favorably protecting the barrier layer, and is 55 μm or less, 50 μm or less, or 45 μm or less as a lid material. It is preferable from the viewpoint of improving the handleability.

<Absorbent layer>
An absorption layer is a layer containing the resin composition for absorption layers and an absorber. The absorbent may be dispersed in the absorbent layer resin.

  The content of the absorbent in the absorbent layer is 1% by mass or more, 3% by mass or more, 5% by mass or more, 7% by mass or more, based on the mass of the entire absorption layer, from the viewpoint of ensuring good absorption capacity. Alternatively, it is preferably 10% by mass or more, and from the viewpoint of ensuring good film forming properties, it is 70% by mass or less, 65% by mass or less, 60% by mass or less, 55% by mass or less, or 50% by mass or less. It is preferable.

  In particular, in the case of the embodiment of (ii) above, the absorbent layer contains a polyethylene resin and an acid-modified polyolefin, and the absorbent layer and the easily peelable layer are bonded to such an extent that a fracture portion is generated. From the viewpoint of making it. In this case, the content of the acid-modified polyolefin is 10% by mass or more, 12% by mass or more, or 15% by mass or more based on the mass of the entire absorption layer from the viewpoint of strongly adhering the absorption layer and the easily peelable layer. In addition, from the viewpoint of securing good film forming properties, it is preferably 35% by mass or less, 30% by mass or less, 25% by mass or less, or 20% by mass or less.

  Further, from the viewpoint of improving the permeability and moldability of the substance to be absorbed by the absorption layer, it is preferable to use LDPE, LLDPE, MDPE, HDPE as the polyethylene resin. Further, from the viewpoint of improving the adhesion between the absorbent layer and the easily peelable layer, it is preferable to use, for example, maleic anhydride-modified polyolefin as the acid-modified polyolefin.

  The thickness of the absorption layer is preferably 1 μm or more, 2 μm or more, 3 μm or more, 5 μm or more, 10 μm or more, 20 μm or more, or 30 μm or more from the viewpoint of securing a good absorption capacity, and 100 μm or less, 90 μm or less. Or 80 μm or less is preferable from the viewpoint of ensuring the flexibility of the lid.

{Resin composition for absorbing layer}
As a resin composition for absorption layers, a thermoplastic resin can be used individually or in mixture, for example.

  Examples of the thermoplastic resin include polyethylene resins, polypropylene resins, saturated or unsaturated polyesters, ionomers, polyvinyl chloride (PVC), polystyrene, and derivatives thereof, and mixtures thereof.

When the absorption layer is intended to absorb water vapor, the water vapor permeability according to JIS K 7129 of the resin is 5 g / (m when measured on a film having a thickness of 25 μm at 40 ° C. and a relative humidity of 90%. ² · day) or more, 10 g / (m ² · day) or more, or 15 g / (m ² · day) or more is preferable from the viewpoint of securing a good absorption rate, and 100 g / (m ² · day). ) Below, 90 g / (m ² · day) or less, or 80 g / (m ² · day) or less is preferable from the viewpoint of preventing deactivation in the production process.

When the absorption layer is intended to absorb oxygen, the oxygen permeability of the resin according to JIS K7126-1 is 5000 cc / (when measured on a film having a thickness of 25 μm at 25 ° C. and 0% relative humidity. m ² · day · MPa) or more, preferably 10,000 cc / (m ² · day · MPa) or more, or 30000 cc / (m ² · day · MPa) or more from the viewpoint of securing a good absorption rate. The viewpoint of preventing deactivation in the production process to be 230,000 cc / (m ² · day · MPa) or less, 200000 cc / (m ² · day · MPa) or less, or 150,000 cc / (m ² · day · MPa) or less. To preferred.

{Absorbent}
As the absorbent, a hygroscopic agent and a gas absorbent can be used.

  As the moisture absorbent, a physical moisture absorbent such as hydrophilic zeolite or silica gel, a chemical moisture absorbent such as calcium oxide, magnesium sulfate, calcium chloride, calcium oxide, or aluminum oxide can be used.

  As the hydrophilic zeolite, for example, A-type, X-type, or LSX-type zeolite can be used. These may be used alone or in combination.

  Gas absorbers include chemical gas absorbers such as activated carbon, hydrophobic zeolite, and other physical gas absorbers, iron oxygen absorbers, metal halides, metal oxides, sulfates, sulfites, hydrogen sulfites, and nitrites. An agent can be used.

  As the hydrophobic zeolite, for example, beta type, ZSM-5 type, ferrierite type, mordenite type, L type, or Y type zeolite can be used. Further, ZSM-11, silicalite, silicalite-2, and pentasil-type metallosilicate, which are analogs of ZSM-5 type zeolite, can also be used. These may be used alone or in combination.

  As the iron-based oxygen absorbent, iron powder (for example, reduced iron powder, sprayed iron powder, active iron powder, etc.), ferrous oxide, ferrous salt, and the like can be used.

  As the metal halide, for example, calcium chloride, sodium chloride, sodium bromide, sodium iodide, potassium chloride, potassium bromide, potassium iodide, calcium chloride, magnesium chloride, barium chloride and the like can be used.

  As the metal oxide, for example, calcium oxide, aluminum oxide, cerium oxide having oxygen defects, titanium oxide having oxygen defects, or the like can be used.

{Acid-modified polyolefin}
The acid-modified polyolefin is obtained by graft polymerization of an acid onto the polyolefin. As the acid-modified polyolefin, for example, maleic anhydride-modified polyolefin is used. As polyolefin, said polyolefin is used suitably. A plurality of acid-modified polyolefins may be used in combination.

  For example, as maleic anhydride-modified polyolefin, maleic anhydride is 0.05 parts by weight or more, 0.1 parts by weight or more, 0.3 parts by weight or more, 0.5 parts by weight or more with respect to 100 parts by weight of polyolefin. Alternatively, it may be 1.0 part by mass or more and 50 parts by mass or less, 30 parts by mass or less, 20 parts by mass or less, 10 parts by mass or less, or 5.0 parts by mass or less by graft polymerization. Examples of such maleic anhydride-modified polyolefin include those described in JP-A-9-27895.

<Easily peelable resin layer>
The easily peelable layer is a layer containing an easily peelable resin composition.

  The thickness of the easily peelable layer is preferably 5 μm or more, 7 μm or more, or 10 μm or more, and preferably 30 μm or less, 25 μm or less, or 20 μm or less from the viewpoint of ensuring good adhesiveness.

{Easily peelable resin composition}
As the easily peelable resin composition, for example, a polyethylene resin, a polypropylene resin, polyvinyl chloride, polystyrene, a thermoplastic elastomer, an ionomer resin, or the like can be used alone or in combination.

  The easily peelable resin composition is preferably a polypropylene resin from the viewpoint of realizing easy peelability.

  In particular, in the case of the above embodiment (ii), the easily peelable resin composition has a tensile fracture nominal strain in accordance with JIS K 7161 from the viewpoint of satisfactorily producing the fracture portion mentioned with reference to FIG. Is preferably a thermoplastic resin having a content of 150% or less. An example of such a thermoplastic resin is homopolypropylene.

<Protective layer>
The protective layer prevents the falling off of the absorbent contained in the absorbent layer and the direct contact with the contents of the absorbent, improves the film formation stability of the absorbent layer, and smoothes the surface to be laminated with the base material layer. It is an optional layer that is fused to the absorbent layer between the base material layer and the absorbent layer in order to impart properties.

  The thermoplastic resin mentioned regarding the absorption layer can be used for a protective layer. In particular, when the protective layer is fused to the absorbent layer, the protective layer contains at least one selected from the group consisting of polyethylene resin, block polypropylene, and random polypropylene. This is preferable from the viewpoint of preventing delamination between the layers.

  Moreover, it is preferable that the protective layer contains an acid-modified polyolefin from the viewpoint of improving adhesion with the absorbent layer and thereby preventing delamination between the protective layer and the absorbent layer. As the acid-modified polyolefin, the acid-modified polyolefins mentioned for the absorption layer can be used. In this case, the content of the acid-modified polyolefin is 15% by mass or more, 17% by mass or more, or 20% by mass or more based on the mass of the entire protective layer from the viewpoint of strongly adhering the absorption layer and the protective layer. In view of ensuring good film forming properties, it is preferably 35% by mass or less, 30% by mass or less, or 25% by mass or less.

<Method for producing blister pack lid material>
The lid material for blister packs of the present invention is a film forming process for forming an easily peelable layer, an absorbent layer, and an optional protective layer, a first layer in which an easily peelable layer, an absorbent layer, and an optional protective layer are laminated. It can manufacture by the method of including the 2nd lamination process which laminates | stacks a base material layer on a lamination process, an absorption layer, or a protective layer.

<Film forming process and first lamination process>
In the film forming step, the resin composition constituting each layer is kneaded using, for example, a batch kneader such as a kneader, a banbury mixer, or a mixing roll conical mixer, or a continuous kneader such as a twin-screw kneader. The product can be formed into a film by extrusion or injection molding such as an inflation method, a T-die method, or a casting method.

  The first laminating step may be performed via an adhesive layer by a dry laminating method, a sand laminating method, etc., but from the viewpoint of ensuring ease of manufacture and absorption performance, a multilayer inflation method or a multilayer T-die method It is preferable to carry out together with the film forming process by a co-extrusion method such as.

<Second lamination process>
In the second lamination step, for example, the base material layer and the protective layer or the absorption layer can be performed via the adhesive layer by a dry lamination method, a sand lamination method, or the like.

《Blister pack with contents》
The blister pack with contents includes the contents, a blister container, and a lid. The blister container has a pocket. As this lid material, the above-mentioned lid material for blister packs can be used.

The easily peelable layer of the lid material is fused to the blister container, whereby the contents are accommodated in the pockets, and the blister container and the easily peelable layer are joined together, And a non-joined portion corresponding to the pocket of the blister container and not joined to the blister container and the easily peelable layer is formed, and when the lid is peeled off,
(I) The blister container can be interfacely peeled from the easily peelable layer, or (ii) In the joint part, the easily peelable layer follows the blister container and in the non-joint part, the easily peelable layer Can follow the absorbing layer.

  In particular, in the case of the above embodiment (ii), the resin composition and the easily peelable resin composition constituting the surface bonded to the easily peelable layer of the blister container both contain a polypropylene resin. It is preferable that the resin composition for an absorbent layer contains a polyethylene resin and an acid-modified polyolefin from the viewpoint of realizing the peeling mechanism mentioned with reference to FIG.

<Contents>
The contents are not limited as long as they can be deteriorated by contact with the outside air, and examples thereof include foods, cosmetics, sanitary products, medical equipment, medical instruments, and electronic parts in addition to drugs. Moreover, as a chemical | medical agent, besides a pharmaceutical formulation, a cleaning agent, an agrochemical, a reagent, etc. are included.

<Blister container>
As the blister container, a blister container having a pocket can be used.

  A blister container can be manufactured by, for example, forming a pocket for containing contents in a sheet for a blister container. Examples of the molding method for molding the pocket include a flat plate air forming method, a plug assist pressure forming method, a drum type vacuum forming method, and a plug forming method. Among these, a plug molding method using a columnar rod (plug material) made of an ultrahigh molecular weight polyethylene resin having a viscosity average molecular weight of 1 million or more and having a rounded tip is preferable for forming a pocket.

  As the blister container, a single-layer blister container sheet or a multi-layer blister container sheet in which a plurality of layers are laminated can be used. The thickness of the blister container sheet can be set to, for example, 500 μm or less, 400 μm or less, 300 μm or less, 200 μm or less, 150 μm or less, or 100 μm or less from the viewpoint of appropriate strength, stiffness, barrier properties, etc. Also, it can be 50 μm or more, 60 μm, or 70 μm or more.

  The material for the single layer blister container sheet is polyethylene resin, polypropylene resin, polyvinyl chloride (PVC), saturated polyester (for example, polyethylene terephthalate), polyamide (for example, nylon (registered trademark), nylon 6, nylon). 6,6, nylon MXD6), cyclic polyolefin (cyclic olefin polymer (COP), cyclic olefin copolymer (COC)), and fluororesin (for example, polychlorotrifluoroethylene (PCTFE), polytetrafluoroethylene (PTFE)) Etc.

  The multilayer blister container sheet may have a base material layer and a sealing resin layer. Moreover, you may provide a barrier layer, a reinforcement layer, etc. arbitrarily between a base material layer and a sealing resin layer, for example, it has a base material layer, a barrier layer, a reinforcement layer, and a sealing resin layer in this order. Examples of a method for bonding adjacent layers include a dry laminating method and a sand laminating method.

(Base material layer for blister containers)
The resin used for the base layer for the blister container is not particularly limited as long as it provides a suitable barrier property and moldability to the blister container sheet. For example, polyethylene resin, polyvinyl chloride, polyvinylidene chloride, polypropylene resin, saturated polyester, polyamide (for example, nylon (registered trademark), nylon 6, nylon 6,6, nylon MXD6), cyclic polyolefin (COP, COC) , And fluorine-based resins (for example, polychlorotrifluoroethylene, polytetrafluoroethylene) and the like, and mixtures thereof. These may be used as a single layer, or two or more layers may be laminated. Preferably, those that prevent moisture from entering from the outside and have excellent moisture resistance are preferable, and polypropylene resins, polyamides, and saturated polyesters are particularly preferable.

  The thickness of the base material layer may be 10 μm or more, 20 μm or more, or 30 μm or more from the viewpoint of maintaining barrier properties and giving strength to the entire blister pack, and is 300 μm or less, 200 μm or less, or 100 μm or less. It may be.

(Barrier layer for blister containers)
Materials used for the barrier layer for blister containers include metal foils such as aluminum foil, silica vapor deposited films, aluminum vapor deposited films, alumina vapor deposited films, silica / alumina vapor deposited films, vinylidene chloride coated films, polyvinylidene fluoride coated films, and the like. A combination of these can be mentioned. The thickness of the barrier layer may be 7 μm or more, 10 μm or more, or 20 μm or more, and is 60 μm or less, 50 μm or less, or 40 μm or less in order to give a suitable formability and barrier property to the blister container sheet. Good.

(Reinforcing layer for blister containers)
The reinforcing layer for blister containers is used for improving the formability of the sheet for blister containers. Examples of the resin used for the reinforcing layer include high density polyethylene, polyvinyl chloride, polypropylene resin, polyethylene terephthalate, polyamide (for example, nylon (registered trademark), nylon 6, nylon 6,6, nylon MXD6), and the like. These mixtures are mentioned. The thickness of the reinforcing layer may be, for example, 10 μm or more, 15 μm or more, or 25 μm or more, and may be 60 μm or less, or 50 μm or less.

(Seal resin layer for blister containers)
The blister container sealing resin layer is a layer for joining with the blister pack lid material of the present invention. Examples of the resin used in the blister container include polyethylene resin, polypropylene resin, polyvinyl chloride, polystyrene, and thermoplastic resin. Examples thereof include elastomers, ionomer resins, and the like, and mixtures thereof. The thickness of the sealing resin layer may be 300 μm or less, 200 μm or less, 150 μm or less, 130 μm or less, or 100 μm or less, and 10 μm or more, 20 μm or more, 30 μm or more, from the viewpoint of imparting suitable moldability to the blister container sheet. , 40 μm, or 50 μm or more.

  The seal resin layer can be an absorbent-containing resin layer containing an absorbent in a thermoplastic resin, or a laminate in which a thermoplastic resin layer is laminated on at least one surface thereof. The absorbent layer of the lid material and the absorbent-containing resin layer of the blister container sheet may be the same, or within the range where the lid material and the blister container can be bonded, the layer thickness and absorption You may use what differs in the kind or content of an agent or resin.

<Cover material>
The lid member may be the blister pack lid member described above.

"combination"
The combination of the present invention is a combination of a blister pack lid and a blister container having a pocket.

In this combination, the easily peelable layer is fused to the blister container, so that it corresponds to the joint where the blister container and the easily peelable layer are joined, and the pocket of the blister container, and easily peeled from the blister container. When the non-bonded part that is not bonded to the adhesive layer is formed and the cover material is peeled off,
(I) The blister container can be interfacely peeled from the easily peelable layer, or (ii) In the joint part, the easily peelable layer follows the blister container and easily peelable in the non-joined part. The layer can follow the absorbing layer.

  As the cover material for blister pack and the blister container, the cover material for blister pack and the blister container described above can be used, respectively.

  The present invention will be specifically described with reference to Examples and Comparative Examples, but the present invention is not limited to these.

<Production of blister pack lid material>
Example 1
By multilayer extrusion molding with a T-die, an easily peelable layer, an absorbent layer, and a protective layer were arranged in this order to prepare a two-kind three-layer absorbent film. As the easily peelable layer, linear low density polyethylene (Evolue SP2520, Prime Polymer Co., Ltd.) is used, and as the absorption layer, hydrophilic zeolite (Molecular Sieve 4A, Union Showa Co., Ltd.) and low density polyethylene (Petrocene (registered trademark)) are used. ) 202, Tosoh Corporation) was used in a mass ratio of 50:50, and a linear low density polyethylene was used as the protective layer. The thickness of each layer was 10 μm for the easily peelable layer, 60 μm for the absorption layer, and 10 μm for the protective layer.

  Next, the laminate of PET (12 μm) // aluminum foil (9 μm) as a base material layer was placed on the protective layer side of the produced absorbent film, and the dry laminate adhesive (Takelac A-525S / Takenate A- 50, Mitsui Chemicals, Inc.) to produce a lid for the prestar pack of Example 1.

<Examples 2 to 9>
The type and content of the resin constituting the easily peelable resin layer, the content of the hydrophilic zeolite, the low density polyethylene and the acid-modified polyolefin constituting the absorption layer, and the type and content of the resin constituting the protective layer The cover material for blister packs of Examples 2 to 9 was produced in the same manner as in Example 1 except that a two-type three-layer or three-type three-layer absorbent film was produced.

As other resins mentioned in Table 1, the following resins were used:
Homopolypropylene (PP): Novatec (registered trademark) PP MA3H, Nippon Polypro Corporation Random PP: Novatec (registered trademark) PP FX4G, Nippon Polypro Corporation Block PP: Novatec (registered trademark) PP BC6DRF, Nippon Polypro Corporation Acid-modified polyolefin: Admer PF508, Mitsui Chemicals, Inc.

<Evaluation>
<Peel test>
The unstretched polypropylene (CPP) film (Trefan ZK-100, Toray Industries, Inc.) as the blister container sheet (10) and the produced blister pack lid material (10) were each cut into 10 cm squares, as shown in FIG. The CPP film is down, the blister pack lid is up, and the upper mold temperature is 190 ° C., the lower mold temperature is 130 ° C., the sealing time is 3 seconds, and the sealing pressure is 0.2 MPa. The junction (14a) of FIG. 4 was formed.

  Next, the region other than the joining portion (14a) and the non-joining portion (14b) in FIG. 4 was cut off, and the CPP film was peeled in the direction of the arrow.

{Easy opening}
Whether the absorbent layer was separated from the CPP film without breaking during peeling was evaluated. In Table 1, the case where the absorbent layer is separated from the CPP film without breaking is indicated by ◯, and the other cases are indicated by x.

{First and second fracture parts}
It was observed whether or not the easily peelable layer was broken at the first break (142) and the second break (144) in FIG. In Table 1, the case where the easily peelable layer breaks is indicated by “◯”, and the case where the easily peelable layer does not break is indicated by “x”.

{Delamination points}
During the peeling, it was observed whether peeling occurred between the moisture absorption layer and the easily peelable layer and between the moisture absorption layer and the protective layer. In Table 1, what peeled between the moisture absorption layer and the easily peelable layer was set to "1", and what peeled between the moisture absorption layer and the protective layer was set to "2."

  The results are shown in Table 1.

  From Table 1, it can be confirmed that all of the lid materials for blister packs of Examples 1 to 9 can be easily opened without breaking the absorbent layer because they have easy-openability.

  Also, among these, the easily peelable resin is a polypropylene resin that is the same kind as the resin constituting the blister container sheet, and the absorption layer contains a polyethylene resin and an acid-modified polyolefin, Examples 4 to The lid material for blister pack No. 9 was broken at both the first and second fracture portions, and was configured to realize the peeling mechanism (ii) above.

DESCRIPTION OF SYMBOLS 10 Cover material for blister packs 12 Absorbing layer 14 Easily peelable layer 14a Joining part 14b, 14b 'Non-joining part 142, 142' (First) Breaking part 144 Second breaking part 16 Protective layer 18 Base material layer 20 Blister container 22 Pocket 30 contents

Claims (9)

It has a base material layer, an absorption layer, and an easily peelable layer in this order,
The absorbent layer contains a resin composition for an absorbent layer, and an absorbent,
The easily peelable layer contains an easily peelable resin composition,
Blister pack lid. The easily peelable layer is fused to a blister container having a pocket, thereby corresponding to the joint where the blister container and the easily peelable layer are joined, and the pocket of the blister container, and When the blister container and the easily peelable layer form a non-joined part that is not joined, and the lid material is peeled off,
(I) The blister container can be interfacially peeled from the easily peelable layer, or (ii) In the joint part, the easily peelable layer follows the blister container and the non-joined part. In, the easily peelable layer can follow the absorption layer,
The lid according to claim 1.   The lid according to claim 1 or 2, wherein the absorbent layer and the easily peelable layer are fused to each other.   The lid | cover material as described in any one of Claims 1-3 further equipped with the protective layer fuse | melted by the said absorption layer between the said base material layer and the said absorption layer. The absorbent layer resin composition contains a polyethylene resin and an acid-modified polyolefin, and the easily peelable resin composition is a polypropylene resin.
The lid | cover material as described in any one of Claims 1-4. A group further comprising a protective layer fused to the absorbent layer between the base material layer and the absorbent layer, and the protective layer is made of polyethylene resin, block polypropylene, and random polypropylene It is composed of at least one kind selected from
The lid according to claim 5. A blister pack having contents, a blister container, and a lid,
The blister container has a pocket;
The lid material includes a base material layer, an absorption layer, and an easily peelable layer,
The absorbent layer contains a resin composition for an absorbent layer, and an absorbent,
The easily peelable layer contains an easily peelable resin composition, and the easily peelable layer is fused to the blister container, whereby the contents are accommodated in the pockets, And a joint part where the blister container and the easily peelable layer are joined, and a non-joint part corresponding to the pocket of the blister container and where the blister container and the easily peelable layer are not joined. And when the lid is peeled off,
(I) The blister container can be interfacially peeled from the easily peelable layer, or (ii) In the joint part, the easily peelable layer follows the blister container and the non-joined part. In, the easily peelable layer can follow the absorption layer,
Blister pack with contents. The resin composition constituting the surface bonded to the easily peelable layer of the blister container and the easily peelable resin composition are both polypropylene resins,
The absorbent layer resin composition contains a polyethylene resin and an acid-modified polyolefin,
The blister pack with contents according to claim 7. A lid for blister packs;
A combination with a blister container having a pocket,
The lid material comprises a base material layer, an absorption layer, and an easily peelable resin layer,
The absorbent layer contains an absorbent layer resin composition and an absorbent, and the easily peelable resin layer contains an easily peelable resin composition,
The easily peelable layer is fused to the blister container so that the blister container and the easily peelable layer are joined to each other, and the blister container corresponds to the pocket of the blister container. And forming the non-bonded portion where the easily peelable layer is not bonded, and peeling the lid material,
(I) The blister container can be interfacially peeled from the easily peelable layer, or (ii) In the joint part, the easily peelable layer follows the blister container and the non-joined part. In, the easily peelable layer can follow the absorption layer,
combination.

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