JP2018175285A - Dialysis powder dissolving apparatus and dialysis powder dissolving method - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a dialysis powder dissolving apparatus and dialysis powder dissolving method capable of easily and reliably dissolving the dialysis powder that is stuck to an inner peripheral wall surface of a dissolution bath in a dialysis powder dissolution process.SOLUTION: The dialysis powder dissolving apparatus includes: a liquid delivery pump P1 capable of delivering liquid in a first dissolution bath 2 to a second dissolution bath 3; an overflow line L5 causing liquid exceeding a prescribed liquid level in the second dissolution bath 3 to flow to the first dissolution bath 2; stirring means 4 disposed at the second dissolution bath; and control means 5 for controlling the liquid delivery pump P1 to deliver the liquid at discretionary timing. The dialysis powder dissolving apparatus dissolves the dialysis powder stored in the second dissolution bath 3, in water fed to the first dissolution bath 2 to create dialysis liquid concentrate. In the dialysis powder dissolution process, the control means 5 controls the liquid delivery pump P1 to perform a liquid level lowering process of lowering the liquid level in the second dissolution bath 3.SELECTED DRAWING: Figure 5

Description

  The present invention relates to an apparatus for dissolving a dialysis powder and a method for dissolving a dialysis powder in order to dissolve a dialysis powder to obtain a dialysis stock solution.

  The dialysate used to treat renal failure patients in hospitals etc. is generally divided into bicarbonate type and acetic acid type, among which the bicarbonate type dialysate does not contain sodium bicarbonate (hereinafter referred to as It is prepared by mixing water with two kinds of agents such as agent A) and sodium bicarbonate (hereinafter referred to as agent B). In recent years, attempts have been made to dissolve powders of the agent A and agent B (hereinafter referred to as "dialysis powder") immediately before or during dialysis treatment from the viewpoint of improving the transportability.

  That is, it is preferable to use for treatment as soon as possible after dissolution from the viewpoint of cleanliness, from the viewpoint of cleanliness, the undiluted solution prepared by dissolving the powder for dialysis (undiluted solution of undiluted solution A or undiluted solution B) In particular, it is not preferable to prepare B stock solution and leave it for a long time because the B solution may change with time, so it is necessary to prepare A and B stock solutions just before dialysis treatment. Furthermore, if there is a shortage of A and B stock solutions during dialysis treatment, it is necessary to additionally prepare each of the stock solutions.

  However, when the first dialysis treatment of the day is performed in a medical facility, a dissolution apparatus has been proposed that can dissolve (prepare dissolution) the dialysis powder previously input before the treatment. For example, conventionally, two dissolution tanks are provided, and the dialysis powder is previously charged into one of the dissolution tanks, for example, on the night of the day before treatment, and water is supplied from the water supply source to the other dissolution tank just before treatment There is disclosed a dissolving apparatus capable of preparing a stock solution for dialysis by dissolving water while being fed to one dissolution tank while circulating and dissolving the powder for dialysis (see Patent Document 1).

Unexamined-Japanese-Patent No. 2001-9028

  However, in the above-mentioned prior art, when water is fed and circulated to the dissolving tank in which the powder for dialysis is stored in advance, the inner peripheral wall surface of the dissolving tank (in particular, the solution in which the powder medicine for dialysis is stored in advance) The powder for dialysis which contained water and solidified may stick to the inner peripheral wall surface in the upper part of the tank, and it was necessary to set the dissolution time to be longer beforehand. In addition, even if the lower part of the dissolution tank is equipped with the stirring means, the stirring effect can not be sufficiently exerted on the upper part of the dissolution tank, and the powder for dialysis which can not be completely adhered adheres to the inner peripheral wall surface in the upper part of the dissolution tank There are times when

  The present invention has been made in view of such circumstances, and is a powder for dialysis capable of dissolving the powder for dialysis fixed on the inner peripheral wall surface of the dissolving tank in the process of dissolving the powder for dialysis easily and reliably. It is an object of the present invention to provide an apparatus for dissolving agents and a method for dissolving dialysis powder.

  The invention according to claim 1 is a first dissolving tank capable of containing a predetermined volume of water supplied from a water supply source, a second dissolving tank capable of accommodating a powder for dialysis in advance, and a bottom part of the first dissolving tank And a first flow path through which fluid is allowed to flow between the first and second dissolution tanks, the first flow path being attached to the first flow path, A liquid transfer pump capable of transferring the liquid of the dissolution tank to the second dissolution tank, and the upper part of the first dissolution tank and the upper part of the second dissolution tank are communicated to make a predetermined in the second dissolution tank. The second flow path which can cause the liquid exceeding the liquid level to flow to the first dissolution tank, and the second dissolution tank, and stirring the liquid which has flowed to the second dissolution tank in the first flow path Stirring means, and control means for controlling the feed pump to feed the liquid at an arbitrary timing, and the first dissolving tank and the second dissolving tank By dissolving the dialysis powder contained in the second dissolution tank with the water supplied to the first dissolution tank by circulating the liquid at the dissolution of the dialysis powder capable of preparing a dialysis stock solution In the above, the control means may perform a liquid level lowering step of lowering the liquid level in the second dissolution tank by controlling the liquid transfer pump in the dissolution process of the powder for dialysis. .

  According to a second aspect of the present invention, in the dissolution apparatus for a powder for dialysis according to the first aspect, there is a difference in height between the first dissolution tank and the second dissolution tank, and the driving of the liquid feed pump is stopped. Alternatively, the liquid level lowering step is performed by driving the liquid transfer pump intermittently.

  The invention according to claim 3 is the dissolution apparatus for a powder for dialysis according to claim 1, wherein the liquid feed pump can be driven reversely, and the liquid level lowering step is performed by the reverse drive. It features.

  The invention according to claim 4 is the dissolution apparatus for a powder for dialysis according to any one of claims 1 to 3, wherein the second dissolution tank is in the liquid level lowering step or after the liquid level lowering step It is characterized in that it comprises a water spray means capable of sprinkling toward the dialysis powder fixed on the inner peripheral wall surface.

  The invention according to claim 5 is the dissolution apparatus for a powder for dialysis according to any one of claims 1 to 3, wherein the second dissolution tank is in the liquid level lowering step or after the liquid level lowering step It is characterized in that it comprises vibration applying means capable of applying vibration to the powder for dialysis fixed on the inner peripheral wall surface.

  The invention according to claim 6 is a first dissolving tank capable of containing a predetermined volume of water supplied from a water supply source, a second dissolving tank capable of accommodating a powder for dialysis in advance, and a bottom part of the first dissolving tank And a first flow path through which fluid is allowed to flow between the first and second dissolution tanks, the first flow path being attached to the first flow path, A liquid transfer pump capable of transferring the liquid of the dissolution tank to the second dissolution tank, and the upper part of the first dissolution tank and the upper part of the second dissolution tank are communicated to make a predetermined in the second dissolution tank. The second flow path which can cause the liquid exceeding the liquid level to flow to the first dissolution tank, and the second dissolution tank, and stirring the liquid which has flowed to the second dissolution tank in the first flow path Stirring means, and control means for controlling the feed pump to feed the liquid at an arbitrary timing, and the first dissolving tank and the second dissolving tank By circulating the liquid in the first dissolution tank to dissolve the dialysis powder contained in the second dissolution tank with the water supplied to the first dissolution tank to produce a dialysis dialysis solution powder capable of preparing a dialysis stock solution In the dissolution method, in the dissolution process of the powder for dialysis, a liquid level lowering step of lowering the liquid level in the second dissolution tank is performed by controlling the liquid transfer pump.

  The invention according to claim 7 is the dissolution method for a dialysis powder according to claim 6, wherein the difference in level between the first dissolution tank and the second dissolution tank is obtained, and the driving of the liquid feed pump is stopped. Alternatively, the liquid level lowering step is performed by driving the liquid transfer pump intermittently.

  The invention according to claim 8 is the dissolution method for a powder for dialysis according to claim 6, wherein the liquid feed pump is capable of reverse driving, and the liquid level lowering step is performed by driving the reverse driving. It features.

  The invention according to claim 9 is the method for dissolving a powder for dialysis according to any one of claims 6 to 8, wherein the liquid level decreasing step or the liquid level decreasing step is performed within the second dissolving tank. The method is characterized in that water is sprayed toward the dialysis powder fixed on the peripheral wall surface.

  The invention according to claim 10 relates to the method for dissolving a powder for dialysis according to any one of claims 6 to 8, wherein in the liquid level lowering step or after the liquid level lowering step, the inside of the second dissolution tank It is characterized in that vibration is applied to the powder for dialysis fixed to the peripheral wall surface.

  According to the first and sixth aspects of the invention, in the dissolution process of the powder for dialysis, the liquid level lowering step of reducing the liquid level in the second dissolution tank is performed by controlling the liquid feed pump. The powder for dialysis fixed on the inner peripheral wall surface of the dissolving tank in the process of dissolving the powder can be dissolved easily and reliably.

  According to the invention of claims 2 and 7, the liquid has a difference in height between the first dissolution tank and the second dissolution tank, and stops the driving of the liquid feed pump or intermittently drives the liquid feed pump. Since the step of reducing the liquid level is performed, the liquid level decreasing step can be performed by causing the liquid in the second dissolution tank to flow out toward the first dissolution tank by its own weight under the control of the liquid feed pump.

  According to the third and eighth aspects of the present invention, the liquid feed pump can be driven in reverse, and the liquid level lowering step is performed by driving the liquid in reverse, so that the second solution tank is driven by the reverse drive of the liquid feed pump. The liquid level lowering step can be performed by forcing the liquid to flow out toward the first dissolution tank.

  According to the invention of claims 4 and 9, since the water is sprayed toward the powder for dialysis fixed on the inner peripheral wall surface of the second dissolving tank during the liquid level lowering step or after the liquid level lowering step, the powder for dialysis fixed. Peeling of the agent from the inner peripheral wall surface can be promoted by water spray.

  According to the invention of claims 5 and 10, since the vibration is applied to the powder for dialysis fixed to the inner peripheral wall surface of the second dissolving tank during the liquid level decreasing step or after the liquid level decreasing step, the fixed dialysis Peeling of the powdery preparation from the inner peripheral wall surface can be promoted by vibration.

The perspective view which shows the dissolution apparatus which concerns on embodiment of this invention Three views showing the same dissolution apparatus III-III sectional view in FIG. 2 A schematic view showing a blood purification system to which the same dissolution apparatus is applied Schematic diagram conceptually showing the configuration of the dissolution apparatus Flow chart showing control contents by control means in the same dissolution apparatus Schematic diagram conceptually showing the configuration (primary water supply) of the dissolution apparatus The schematic diagram which shows notionally the structure (primary water supply preliminary circulation) of the dissolution apparatus Schematic diagram conceptually showing the configuration (liquid level lowering step) of the same dissolution apparatus Schematic diagram conceptually showing the configuration of the dissolution apparatus (primary water supply shower) The schematic diagram which shows notionally the structure (primary water supply circulation) of the dissolution apparatus Schematic diagram conceptually showing the configuration (circulation 1) of the same dissolution apparatus Schematic diagram conceptually showing the configuration (circulation 2) of the same dissolution apparatus Schematic diagram conceptually showing the configuration (final water supply) of the dissolution apparatus Schematic diagram conceptually showing the configuration (final circulation) of the same dissolution apparatus Schematic diagram conceptually showing the configuration (fine adjustment water supply) of the dissolution apparatus Schematic diagram conceptually showing the configuration (concentration measurement) of the same dissolution apparatus Schematic diagram conceptually showing the configuration of the same dissolution apparatus (liquid preparation) Schematic diagram conceptually showing the configuration (liquid transfer) of the dissolution apparatus Schematic diagram conceptually showing the configuration of the dissolution apparatus (liquid feed switching and water supply) Schematic diagram conceptually showing the configuration (additional charge) of the same dissolution apparatus Schematic diagram conceptually showing the configuration of the same dissolution apparatus (liquid transfer switching and transfer)

Hereinafter, embodiments of the present invention will be specifically described with reference to the drawings.
The dissolving apparatus 1 according to the present embodiment dissolves the powder for dialysis to obtain the undiluted solution for dialysis, and as shown in FIGS. 1 to 5, it dissolves the powder for dialysis to obtain the undiluted solution for dialysis. A first dissolution tank 2 and a second dissolution tank 3 capable of storing a predetermined amount of the dissolved dialysis stock solution, a stirring means 4, a control means 5, a liquid level detection means 6, a notification means 7, and a display It comprises the means 8 and the water spray means 9.

  The first dissolution tank 2 can accommodate a predetermined volume of water supplied from a water supply source, and does not contain sodium bicarbonate during dialysis treatment (agent A) or sodium bicarbonate (agent B) And a storage space into which the dialysis powder consisting of any one of the above two types can be charged. A water supply line L1 extended from a water supply source is connected to the first dissolution tank 2. As shown in FIG. 5, a valve V1 comprising an electromagnetic valve or the like is disposed in the water supply line L1, and water can be supplied into the first dissolution tank 2 by opening the valve V1. There is.

  The second dissolving tank 3 has a space which can be accommodated in advance by charging a powder for dialysis (the same kind as the powder for dialysis to be introduced into the first dissolving tank 2 during the dialysis treatment), and as shown in FIG. As shown, a connection line L4 connecting the second dissolution tank 3 and the first dissolution tank 2 is connected. The connection line L4 is provided with valves V2, V3 and V4 formed of solenoid valves etc., and by opening the valves V2, V3 and V4, the liquid in the first dissolution tank 2 is 2 transferable into the dissolving tank 3; The second dissolution tank 3 according to the present embodiment is a tank having a relatively smaller capacity than the first dissolution tank 2, and is connected to the first dissolution tank 2 through the overflow line L5.

  In addition to the water supply line L1 and the connection line L4, the first dissolution tank 2 is connected to the connection line L2. The connection line L2 includes a flow path in which the liquid feed pump P1 is disposed, and one end is connected to the first dissolution tank 2, and the other end is a connection portion b (the valve V2 and the valve V3) in the connection line L4. Connected between). The liquid transfer pump P1 is attached to the connection line L2 (the "first flow path" of the present invention), and comprises a pump capable of transferring the liquid in the first dissolution tank 2 to the second dissolution tank 3.

  Further, the base end of the liquid transfer line L3 is connected to the connection portion a (a position between the disposition site of the liquid transfer pump P1 and the connection portion b) in the connection line L2. The liquid feed line L3 is provided with a pump P2 and a valve V5 formed of a solenoid valve or the like. A connection line L6 in which a valve V6 formed of a solenoid valve or the like is disposed is connected between the liquid transfer line L3 and the connection line L4.

  The pump P2 is disposed in the middle of the liquid transfer line L3, and the tip is connected to the dialysate supply device B (see FIG. 4), and the dialysate supply of the undiluted solution for dialysis prepared by the dissolving device 1 The liquid can be fed to the device B. The dialysate supply device B dilutes the undiluted solution for dialysis sent from the dissolving device 1 to a predetermined concentration to prepare a dialysate, and as shown in FIG. It is connected to the. Thus, the undiluted solution for dialysis prepared by the dissolution apparatus 1 is converted to a dialysate having a predetermined concentration by the dialysate supply apparatus B, and is sent to each dialysis apparatus A to be subjected to dialysis treatment.

  However, the connection lines L2 and L4 allow the bottom of the first dissolution tank 2 and the bottom of the second dissolution tank 3 to communicate with each other so that the liquid can flow between the first dissolution tank 2 and the second dissolution tank 3 The overflow line L5 communicates the upper portion of the first dissolution tank 2 with the upper portion of the second dissolution tank 3 to form a predetermined liquid level in the second dissolution tank 3. It constitutes a “second flow path” that can cause the excess liquid to flow (overflow in this embodiment) to the first dissolution tank 2.

  The stirring means 4 comprises a nozzle disposed on the bottom surface of the second dissolution tank 3 and connected to the connection line L4, and when the liquid flowing in the connection line L4 is introduced into the second dissolution tank 3, The liquid can be stirred by generating a jet in the solution tank 3. In addition, it may be replaced with a nozzle and it is good also as a stirring means of the other form arrange | positioned, for example on the bottom face of the 2nd dissolution tank 3, and having an impeller etc.

The control means 5 comprises, for example, a microcomputer or the like disposed in the present dissolution apparatus 1, and the liquid feed pump P1.
Can be controlled to send the liquid at an arbitrary timing. The control means 5 according to the present embodiment is electrically connected to the pump P2 and the valves V1 to V6, etc. in addition to the liquid feed pump P1, and the timing of the liquid delivery pump P1, the pump P2 and the valves V1 to V6 is arbitrary. It can be operated with That is, by the control of the control means 5, an operation for performing preparation dissolution (dissolution before dialysis treatment) and additional dissolution (dissolution during dialysis treatment) by the present dissolution apparatus 1 is performed.

  Here, the control means 5 of the dissolution apparatus 1 according to the present embodiment reduces the liquid level in the second dissolution tank 3 by controlling the liquid feed pump P1 in the dissolution process of the powder for dialysis. It is configured to be able to carry out the process. More specifically, in the present embodiment, a position where the second dissolution tank 3 is higher than the first dissolution tank 2 (a position where the bottom of the second dissolution tank 3 is above the bottom of the first dissolution tank 2) The liquid produced by the height difference (head difference) is provided by having the height difference between the first dissolution tank 2 and the second dissolution tank 3 and stopping the driving of the liquid transfer pump P1. The liquid level lowering step is performed by causing the liquid in the second dissolving tank 3 to flow toward the first dissolving tank 2 by its own weight.

  The liquid level detection means 6 comprises a sensor disposed in the first dissolution tank 2 and can detect the liquid level of the dialysis stock solution contained in the first dissolution tank 2 continuously and in real time. is there. The liquid level detection means 6 according to the present embodiment is formed of a magnetostrictive linear displacement sensor having a floating means that can move up and down on the liquid surface of the liquid contained in the first dissolution tank 2 The liquid level (i.e., liquid level) can be detected by detecting the position of the means continuously and in real time.

  The liquid level detection means 6 can detect the liquid level of the undiluted solution for dialysis (which may be the supplied water or solution) contained in the first dissolution tank 2 continuously and in real time. For example, any type of contact type or non-contact type may be used, and in addition to the magnetostrictive linear displacement sensor by floating means as in this embodiment, an ultrasonic sensor or the like may be used. Further, in the present embodiment, the liquid level detection means 6 is disposed only in the first dissolution tank 2, but may be disposed in the second dissolution tank 3 together with the first dissolution tank 2. .

  Furthermore, the liquid level detection means 6 is electrically connected to the notification means 7. The notification means 7 can notify the timing of the additional introduction of the powder for dialysis based on the liquid level of the undiluted solution for dialysis detected by the liquid level detection means 6, and a speaker or a warning for outputting sound, sound, etc. It consists of lights and the like. That is, when the liquid level detected by the liquid level detection means 6 is lower than a predetermined height and it is predicted that the undiluted solution for dialysis will run short, the informing means 7 notifies by using the additional dialysis powder. It is possible to additionally prepare the undiluted solution for dialysis by introducing it to workers such as medical workers and additionally dissolving it.

  The display means 8 is attached to the housing of the dissolution apparatus 1 and is constituted by a liquid crystal monitor or the like capable of performing various displays related to the dissolution operation, and is constituted by a touch panel in the present embodiment. Then, by touching the touch panel that constitutes the display means 8, predetermined input is enabled. In the present embodiment, although the touch panel having both predetermined input and display is provided, the input means and the display means may be provided separately.

  The water sprinkling means 9 comprises a shower disposed in the second dissolution tank 3 and is directed toward the powder for dialysis fixed to the inner peripheral wall surface of the second dissolution tank 3 during the liquid level lowering step or after the liquid level lowering step. Sprinkler (water, etc. can be spouted) is possible. That is, in the dissolution process of the powder for dialysis in the preparation dissolution (dissolution before dialysis treatment), water is contained in the inner peripheral wall surface of the portion (upper part of the second dissolution tank 3) where the stirring effect by the stirring means 4 is difficult to achieve. Since the powder for dialysis which has solidified in the case may be fixed, the fixed powder for dialysis can be peeled off from the inner peripheral wall surface by watering and dropped into the liquid.

  The water sprinkling means 9 according to the present embodiment is connected to the water sprinkling line L7 branched from the water supply line L1 extended from the water supply source, and opens the valve V7 (electromagnetic valve) disposed in the water sprinkling line L7. It is possible to water the water by setting the state, and to stop the water water by closing the valve V7. In the present embodiment, the water sprinkling means 9 is attached to the water sprinkling line L7 branched from the water supply line L1, but water for water sprinkling from a water supply source different from the water supply source connected to the water supply line L1. May be obtained.

Next, the operation for preparing and dissolving by the melting apparatus 1 according to the present embodiment will be described based on the flowchart shown in FIG. 6 and the conceptual diagrams shown in FIGS.
First, in order to carry out preparation dissolution, as shown in FIG. 7, a predetermined amount (number of preparation dissolution bags) of dialysis powder is added to the second dissolution tank 3 before dialysis treatment (the night on the day before treatment, etc.) In advance. Then, as shown in the figure, by performing control by the control means 5, the valves V3 and V7 are closed while the valves V1 and V2 are open, and the liquid feed pump P1 and the pump P2 are stopped. A predetermined amount of water is supplied from the water supply source to the first dissolution tank 2 via the water supply line L1 (S1: primary water supply).

  Thereafter, as shown in FIG. 8, the valves V1, V2 and V5 to V7 were closed while the valves V3 and V4 were opened, and the liquid feed pump P1 was driven to be housed in the first dissolution tank 2 Water is sent to the second dissolution tank 3 (S2: primary water supply preliminary circulation). Thus, the water in the first dissolution tank 2 is previously fed into the second dissolution tank 3 to dissolve the powder for dialysis, and the solution (solution in the process of becoming the undiluted solution for dialysis) flows over the overflow line L5. It will overflow and circulate to the 1st dissolution tank 2 via it.

  Here, in the present embodiment, as shown in FIG. 9, the valves V1 and V5 to V7 are closed while the valves V2 to V4 are opened, and the liquid level drop is caused by stopping the driving of the liquid feed pump P1. Step S3 is performed. That is, in the present embodiment, as described above, the second dissolution tank 3 is disposed at a higher position than the first dissolution tank 2, and between the first dissolution tank 2 and the second dissolution tank 3. Since there is a difference in height, the difference in height (head) can be obtained by stopping the driving of the liquid transfer pump P1 while keeping the valves V2 to V4 open and connecting the first dissolution tank 2 and the second dissolution tank 3 to each other. The liquid level decreasing step S3 is performed by causing the liquid in the second dissolution tank 3 to flow toward the first dissolution tank 2 by the weight of the liquid produced by the difference).

  By the liquid level lowering step S3, the powder for dialysis fixed to the inner peripheral wall portion in the upper part of the second dissolving tank 3 can be positioned above the liquid level. Then, when the liquid level lowering step S3 is performed and a predetermined time passes, as shown in FIG. 10, the valves V1, V5 and V6 are closed while the valves V2 to V4 and V7 are open, and the liquid feed pump P1 The liquid level in the second dissolving tank 3 is lowered by maintaining the stopped state, and the water spray means 9 applies water to the powder for dialysis (powder for dialysis fixed to the inner circumferential wall) facing the outside. Will be performed (S4: primary water supply shower).

  As a result, since the dialysis powder adhered to the inner peripheral wall surface of the second dissolving tank 3 can be positioned above the liquid surface when the liquid level is lowered, the dialysis powder (moisture content (water (The weight increase) can be separated from the inner circumferential wall surface by its own weight and dropped into the liquid. Moreover, peeling and disintegration of the powder for dialysis which adhered to the inner peripheral wall surface of the 2nd dissolution tank 3 can be performed effectively by water sprinkling, and dissolution of the powder for dialysis can be promoted.

  After the above primary water supply shower S4 is performed for a predetermined time, as shown in FIG. 11, the valves V5 to V7 are closed while the valves V1 to V4 are open, and the liquid feed pump P1 is driven to supply water. The liquid is circulated between the first dissolution tank 2 and the second dissolution tank 3 while supplying water from the water source to the first dissolution tank 2 (S5: primary water supply circulation). At this time, it is preferable that the total amount of water supplied to the first dissolution tank 2 be about 90% of a specified amount (the amount of water required to prepare a dialysis solution stock solution of a predetermined concentration).

  Thereafter, as shown in FIG. 12, the valves V1, V2 and V5 to V7 are closed while the valves V3 and V4 are open, and the driving of the liquid transfer pump P1 is continued, whereby one circulation step S6 is performed. At the same time, after a predetermined time elapses, as shown in FIG. 13, the valves V1 and V3 to V7 are closed while the valve V2 is opened, and the driving of the liquid transfer pump P1 is continued, whereby the circulation 2 process S7 is performed It will be.

  After the two circulation steps S7, as shown in FIG. 14, the valves V1 and V2 are opened and the valves V3 to V7 are closed, and the liquid feed pump P1 is stopped to supply the specified amount of water. Final water supply process S8 which will be performed is performed. Further, after the final water supply step S8, as shown in FIG. 15, the final circulation is achieved by closing the valves V1, V2 and V5 to V7 while driving the valves V3 and V4 and driving the liquid feed pump P1. Step S9 is performed.

  After the final circulation step S9 is performed and a predetermined time has elapsed, as shown in FIG. 16, the valves V3 and V7 are closed while the valves V1 and V2 are open, and the liquid feed pump P1 is stopped. Adjustment water supply process S10 is performed. Thereafter, as shown in FIG. 17, the valves V1 and V5 to V7 are closed while the valves V2 to V4 are opened, and the liquid feed pump P1 is driven to make the undiluted dialysis solution prepared by the concentration sensor (not shown). A concentration measurement step S11 for measuring the concentration is performed, and it is determined whether the concentration of the dialysis stock solution is appropriate, and as shown in FIG. 18, the valves V1 to V3 and V7 are opened while the valves V4 to V6 are opened. Is closed, and the liquid feed pump P1 and the pump P2 are driven to perform the liquid feed preparation step S12.

  Thus, as shown in FIG. 19, in the state where the undiluted solution for dialysis is stored in each of the first dissolution tank 2 and the second dissolution tank 3 as described above, the valves V1 to V4, while the valve V5 is opened, The dialysis stock solution in the first dissolution tank 2 may be sent to the dialysate supply device B via the liquid sending line L3 by closing V6 and V7 and driving the liquid sending pump P1 and the pump P2. The dialysis treatment can be performed by supplying each dialysis device A with a predetermined concentration of dialysate (S13: stock solution supply).

Next, an operation for additional dissolution by the dissolution apparatus 1 according to the present embodiment will be described based on conceptual diagrams shown in FIGS.
In the process of feeding the undiluted solution in the first dissolution tank 2 to the dialysate supply device B, the liquid level of the undiluted solution in the first dissolution tank 2 reached a predetermined height by the liquid level detection means 6 When the event is detected, the notification means 7 notifies for additional input. In this case, as shown in FIG. 20, while the valves V1, V2, V4 and V6 are opened, the valves V3, V5 and V7 are closed and water is supplied from the water supply source while the drive of the pump P2 is continued. The dialysis stock solution in the second dissolution tank 3 is sent to the dialysate supply device B in place of the first dissolution tank 2.

  Thus, it is possible to add a predetermined amount (the number of additional input bags) of additional dialysis powder into the first dissolution tank 2, and the input dialysis powder is dissolved by water supply from the water supply source. It will be. In addition, the solution in the process used as the undiluted | stock solution for dialysis can be circulated by driving the liquid feeding pump P1. As a result, instead of the first dissolution tank 2, feeding of the undiluted solution from the second dissolution tank 3 is continued, and an additional dialysis powder is charged and dissolved in the first dissolution tank 2. it can.

  Then, when water supply of a predetermined amount is performed, as shown in FIG. 21, valves V1, V3, V5, and V7 are closed while valves V2, V4, and V6 are open, and water supply from the water supply source is stopped. On the other hand, while the liquid feeding pump P1 and the pump P2 are continuously driven, the feeding of the undiluted solution from the second dissolving tank 3 is continued, and the undiluted solution in the first dissolving tank 2 is circulated. The mixture is then stirred to obtain a stock solution for dialysis having a uniform concentration.

  As described above, in the state in which the undiluted solution for dialysis is stored in the first dissolution tank 2, as shown in FIG. 22, the valves V1, V6 and V7 are closed while the valves V2 to V5 are open, and the liquid feed pump By driving P1 and the pump P2, the dialysis stock solution in the first dissolution tank 2 can be sent to the dialysate supply device B via the liquid sending line L3, and the dialysate of a predetermined concentration is supplied to each dialyzer. A can be supplied to perform dialysis treatment. At this time, a part of the dialysis stock solution in the first dissolution tank 2 is transferred into the second dissolution tank 3, and the dialysis stock solution is fed into the overflow line L5 until it overflows.

  Thereafter, as shown in FIG. 19, the valves V1 to V4, V6, and V7 are closed while the valve V5 is opened, and the liquid feed pump P1 and the pump P2 are driven (either the liquid feed pump P1 or the pump P2 The dialysis stock solution in the first dissolution tank 2 can be sent to the dialysate supply device B via the liquid sending line L3 by driving the Device A can be supplied to perform dialysis treatment. As a result, the undiluted solution for dialysis that is additionally dissolved in the first dissolution tank 2 can be supplied to the dialysate supply device B, so that dialysis treatment by each of the dialysis devices A can be continued.

  As described above, the dissolution apparatus 1 according to the present embodiment sends the undiluted solution for dialysis of the first dissolution tank 2 and the second dissolution tank 3 to the plurality of dialysis devices A for performing dialysis treatment on the patient during dialysis treatment. With the addition of the solution, it is possible to add an additional powder for dialysis every predetermined amount (in this embodiment, into a bag unit (number of bags) containing the powder for dialysis) and dissolve it, so-called batch It consists of a dissolver called the formula.

  According to the above-described embodiment, in the dissolution process of the powder for dialysis, the liquid level reduction step S3 for reducing the liquid level in the second dissolution tank 3 by controlling the liquid transfer pump P1 is performed. The dialysis powder adhering to the inner peripheral wall surface of the second dissolution tank 3 can be dissolved easily and reliably in the dissolution process of the agent. That is, by performing the liquid level lowering step S3 and lowering the liquid level of the second dissolution tank 3 in the dissolution process of the powder for dialysis, the dialysis powder fixed on the inner peripheral wall surface of the second dissolution tank 3 is obtained. Since it can be positioned above the liquid surface, the powder for dialysis can be peeled off from the inner peripheral wall surface by its own weight and fallen into the liquid.

  Further, in the present embodiment, the liquid level lowering step is performed by stopping the driving of the liquid transfer pump P1 while having the difference in height between the first dissolution tank 2 and the second dissolution tank 3, so The liquid level lowering step S3 can be performed by causing the liquid in the second dissolution tank 3 to flow out toward the first dissolution tank 2 by its own weight by the control of the liquid pump P1. Furthermore, in the present embodiment, after the liquid level lowering step S3 (which may be during the liquid level lowering step S3), the water spray means 9 is directed toward the powder for dialysis fixed to the inner peripheral wall surface of the second dissolution tank 3 Since the water is sprayed at this time, it is possible to accelerate the separation of the fixed dialysis powder from the inner peripheral wall surface by the water spray.

  As mentioned above, although this embodiment was described, the present invention is not limited to this, for example, makes liquid sending pump P1 into a pump which can be driven reversely, and even if it makes liquid level fall process S3 be performed by making reverse drive concerned. Good. As described above, if the liquid feed pump P1 can be driven reversely and the liquid level lowering step S3 is performed by the reverse drive, the liquid in the second dissolving tank 3 is driven by the reverse drive of the liquid feed pump P1. The liquid level decreasing step S3 can be performed by forcing the solution to flow out toward the first dissolution tank 2. In this case, it is not necessary to provide a height difference between the first dissolution tank 2 and the second dissolution tank 3, and the degree of freedom in the layout in the dissolution apparatus 1 can be improved.

  Further, instead of the liquid level lowering step S3, the driving of the liquid transfer pump P1 may be performed intermittently between the primary water supply S1 and the primary water supply circulation S5. That is, in the present embodiment, since there is a difference in height between the first dissolution tank 2 and the second dissolution tank 3, the liquid feed pump P1 is intermittently driven (the stop state and the drive state are repeated) Thus, the liquid level in the second dissolution tank 3 can be lowered when the apparatus is stopped. As a result, since the powder for dialysis adhered to the inner peripheral wall surface of the second dissolution tank 3 can be positioned above the liquid surface when the liquid level is lowered, the powder for dialysis is contained by its own weight. It can be separated from the peripheral wall surface and dropped into the liquid.

  Furthermore, instead of the water spray means 9 or together with the water spray means 9, the second dissolving tank 3 applies vibration to the dialysis powder fixed to the inner peripheral wall surface during the liquid level lowering step or after the liquid level lowering step. You may make it comprise the possible vibration provision means (a knocker, an excitation means, etc.). In this case, since the vibration is applied to the powder for dialysis fixed to the inner peripheral wall surface of the second dissolving tank 3 during the liquid level decreasing step or after the liquid level decreasing step, the inner peripheral wall surface of the fixed agent for dialysis fixed Peeling can be promoted by vibration.

  Dissolution device for dialysis powder and dissolution method for dialysis powder, which performs a liquid level decreasing step of lowering liquid level in the second dissolution tank by controlling a liquid feed pump in the dissolution process of powder for dialysis In this case, the present invention can be applied to ones having different appearance shapes or those to which other functions are added.

DESCRIPTION OF SYMBOLS 1 Dissolution device 2 First dissolution tank 3 Second dissolution tank 4 Stirring means 5 Control means 6 Liquid level detection means 7 Informing means 8 Display means 9 Water sprinkling means P1 Liquid transfer pump L1 Water supply line L2 Connection line (first flow path)
L3 Liquid Transfer Line L4 Connection Line (First Flow Path)
L5 overflow line (second flow path)
L6 Connection line L7 Sprinkler line A Dialysis machine B Dialysate supply device

Claims (10)

A first dissolution tank capable of containing a predetermined volume of water supplied from a water supply source;
A second dissolving tank capable of accommodating in advance a powder for dialysis;
A first flow path which allows the bottom of the first dissolution tank and the bottom of the second dissolution tank to communicate with each other to cause a liquid to flow between the first dissolution tank and the second dissolution tank;
A liquid transfer pump attached to the first flow path and capable of transferring the liquid of the first dissolution tank to the second dissolution tank;
A second flow path which allows the upper part of the first dissolution tank and the upper part of the second dissolution tank to communicate with each other to flow the liquid exceeding a predetermined liquid level in the second dissolution tank to the first dissolution tank When,
An agitation unit disposed in the second dissolution tank and capable of stirring the liquid flowing in the second dissolution tank in the first flow path;
Control means capable of controlling the feed pump to feed the liquid at an arbitrary timing;
By circulating a liquid between the first dissolution tank and the second dissolution tank, the powder for dialysis stored in the second dissolution tank with the water supplied to the first dissolution tank In a dissolution apparatus for a dialysis powder which can be dissolved to prepare a stock solution for dialysis,
The control means may perform a liquid level lowering step of lowering the liquid level in the second dissolution tank by controlling the liquid transfer pump in the dissolution process of the powder for dialysis. Powder dissolution equipment.   While having a difference in elevation between the first dissolution tank and the second dissolution tank, the liquid level lowering step is performed by stopping driving of the liquid transfer pump or intermittently driving the liquid transfer pump. The dissolution apparatus for a powder for dialysis according to claim 1, characterized in that   The dissolution pump for dialysis powder according to claim 1, wherein the liquid feed pump is capable of reverse driving, and the liquid level lowering step is performed by the reverse driving.   The second dissolution tank is provided with a water sprinkling means capable of sprinkling toward the powder for dialysis fixed on the inner peripheral wall surface during the liquid level lowering step or after the liquid level lowering step. The dissolution apparatus for a powder for dialysis according to any one of to 3.   The second dissolving tank is characterized in that the liquid level lowering step or after the liquid level lowering step includes vibration applying means capable of giving vibration to the powder for dialysis fixed on the inner peripheral wall surface. The dissolution apparatus for a powder for dialysis according to any one of claims 1 to 3. A first dissolution tank capable of containing a predetermined volume of water supplied from a water supply source;
A second dissolving tank capable of accommodating in advance a powder for dialysis;
A first flow path which allows the bottom of the first dissolution tank and the bottom of the second dissolution tank to communicate with each other to cause a liquid to flow between the first dissolution tank and the second dissolution tank;
A liquid transfer pump attached to the first flow path and capable of transferring the liquid of the first dissolution tank to the second dissolution tank;
A second flow path which allows the upper part of the first dissolution tank and the upper part of the second dissolution tank to communicate with each other to flow the liquid exceeding a predetermined liquid level in the second dissolution tank to the first dissolution tank When,
An agitation unit disposed in the second dissolution tank and capable of stirring the liquid flowing in the second dissolution tank in the first flow path;
Control means capable of controlling the feed pump to feed the liquid at an arbitrary timing;
By circulating a liquid between the first dissolution tank and the second dissolution tank, the powder for dialysis stored in the second dissolution tank with the water supplied to the first dissolution tank In a dissolution method of a powder for dialysis with a dissolution apparatus capable of dissolving to prepare a stock solution for dialysis,
A dissolution method of a dialysis powder, characterized by performing a liquid level lowering step of lowering the liquid level in the second dissolution tank by controlling the liquid transfer pump in the dissolution process of the powder for dialysis.   While having a difference in elevation between the first dissolution tank and the second dissolution tank, the liquid level lowering step is performed by stopping driving of the liquid transfer pump or intermittently driving the liquid transfer pump. The method for dissolving a powder for dialysis according to claim 6, wherein   7. The method according to claim 6, wherein the liquid feed pump is capable of reverse driving, and the liquid level lowering step is performed by the reverse driving.   9. The method according to any one of claims 6 to 8, wherein water is sprayed toward the dialysis powder fixed on the inner peripheral wall surface of the second dissolving tank during the liquid level lowering step or after the liquid level lowering step. Dissolution method of the powder for dialysis described.   9. The method according to any one of claims 6 to 8, characterized in that vibration is applied to the powder for dialysis fixed to the inner peripheral wall surface of the second dissolution tank during the liquid level lowering step or after the liquid level lowering step. Method for dissolving dialysis powder as described in 1).

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