JP2018102910A - Absorbent article - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an absorbent article capable of effectively suppressing an odor of urine or the like caused by absorption of excrement, with a perfume.SOLUTION: An absorber 4 of an absorbent article 1 includes: an absorbent core 40; and a cover sheet 44 covering the same. The absorbent core 40 contains highly absorbent polymer. The highly absorbent polymer contains antibacterial agent. The cover sheet 44 contains a perfume. It is also preferable that the surface of the absorbent core 40 has a polymer absent area where no highly absorbent polymer is present.SELECTED DRAWING: Figure 1

Description

  The present invention relates to an absorbent article.

  In various absorbent articles such as disposable diapers, incontinence pads and sanitary napkins, the absorbent article may be perfumed to mask the odor in order to prevent the odor generated from the absorbed excrement from being perceived. Often done.

  In order to enhance the masking effect by the fragrance, the fragrance is generally applied to the absorbent body in the absorbent article. However, when excrement such as urine absorbed by the absorbent body is mixed with the fragrance, another odor is generated, and the masking effect by the fragrance may be reduced.

  As a conventional technique for suppressing odor generated from excrement absorbed and held in an absorbent article by masking with a fragrance, for example, Patent Document 1 discloses an antibacterial agent of a quaternary ammonium salt between an absorbent layer and a surface sheet. An absorbent article having a functional material region in which a functional material containing a fragrance and a fragrance is disposed has been proposed. By adopting this configuration, the body fluid discharged from the wearer touched the antibacterial agent in the process of being guided from the surface sheet side to the absorption layer side, and the body fluid once absorbed by the absorption layer leaked to the surface sheet side Even in this case, since the body fluid touches the antibacterial agent, the literature discloses that the antibacterial function can be exhibited not only at the time of absorption when the body fluid is absorbed but also after absorption of the body fluid.

JP, 2006-67749, A

  However, the demand for further improvement in the quality of life has been increasing, and the odor control effect required for absorbent articles is also required to be higher than ever. Therefore, the high deodorization suppression effect exceeding the technique of patent document 1 is required.

  Therefore, the subject of this invention exists in improvement of the aromatized absorbent article, and it is providing the absorbent article which can suppress the odor resulting from the absorption of excrement in detail.

The present invention is an absorbent article having a top sheet, a back sheet, and an absorbent body disposed between both sheets,
The absorber includes an absorbent core and a covering sheet that covers the absorbent core,
The absorbent core contains a superabsorbent polymer,
The superabsorbent polymer contains an antibacterial agent,
An absorbent article in which a fragrance is contained in the covering sheet is provided.

  ADVANTAGE OF THE INVENTION According to this invention, the absorbent article which can suppress effectively odors, such as urine odor resulting from absorption of excrement, is provided.

FIG. 1: is thickness direction sectional drawing when cut along the width direction in the center area along a longitudinal direction which shows one Embodiment of the absorbent article of this invention. FIG. 2 is a perspective view of the absorbent core in the absorbent body of the absorbent article shown in FIG. 1 with its non-skin facing surface facing upward. FIG. 3 is a cross-sectional view in the thickness direction along the width direction in the central region along the longitudinal direction of the absorbent core in the absorbent body of the absorbent article shown in FIG. 1. FIG. 4 (a) is a schematic diagram showing the mechanism by which the target odor molecule activates the olfactory receptor, and FIG. 4 (b) shows the receptor of the target odor molecule by olfactory receptor antagonism. It is a schematic diagram which shows the mechanism by which activation is inhibited. FIG. 5 shows the results of a luciferase assay that measures the response of olfactory receptors to p-cresol. The horizontal axis represents individual olfactory receptors, and the vertical axis represents response intensity (n = 2). FIG. 6 shows the results of a luciferase assay measuring the response of olfactory receptors to various concentrations of p-cresol. N = 3 to 4 and error bar = ± SE, respectively. FIG. 7 shows the results of a luciferase assay in which the response of an olfactory receptor to 2-methoxy-4-vinylphenol was measured. The horizontal axis represents individual olfactory receptors, and the vertical axis represents response intensity (n = 2). FIG. 8 shows the results of a luciferase assay measuring the response of olfactory receptors to various concentrations of 2-methoxy-4-vinylphenol. N = 3 to 4 and error bar = ± SE, respectively. FIG. 9 is an analysis result of a luciferase assay that measures the inhibitory effect of the response of the olfactory receptor OR9Q2 by Nectaryl and Bourgeonal. The horizontal axis is the concentration of Nectaryl (left) and Bourgeonal (right), and the vertical axis is the ratio (%) of response intensity in the presence of Nectaryl or Bourgeonal when the response intensity of OR9Q2 to p-cresol alone is 100% ( Average value of three measurements, error bar = standard error). FIG. 10 shows the results of a sensory test in which the effect of suppressing urine odor by an OR9Q2 antagonist was measured. Vehicle = mineral oil only, n = 10, error bar = SEM, * = p <0.01 (Wilcoxon Sine-rank test).

  Below, this invention is demonstrated, referring drawings based on the preferable embodiment. The absorbent article 1 shown in FIG. 1 includes a top sheet 2 disposed on the skin facing surface side, a back sheet 3 disposed on the non-skin facing surface side, and an absorbent body 4 interposed between both sheets 2 and 3. It has a long shape in one direction having a longitudinal direction and a width direction. The absorbent article 1 includes a three-dimensional gather 5 including a water-repellent sheet 6 and an elastic member 61 fixed to the water-repellent sheet 6 on both sides in the longitudinal direction. The solid gather 5 stands up toward the wearer when worn.

  In this specification, the longitudinal direction of the absorbent article means a direction that coincides with the wearer's front-rear direction when worn. Reference to the width direction of the absorbent article means a direction substantially orthogonal to the longitudinal direction. In FIG. 1, the direction indicated by the symbol Y (Y direction) is the width direction of the absorbent article (absorber, absorbent core, three-dimensional gather). Moreover, in this specification, the thickness direction of an absorbent article is a direction shown by Z in FIG. Further, the skin facing surface is a surface directed to the skin side of the wearer when the absorbent article is worn in the absorbent article, and the non-skin facing surface is the skin side when the absorbent article is worn in the absorbent article. Is the surface facing the opposite side (usually the clothing side).

  The top sheet 2 in the absorbent article 1 is liquid permeable. One side of the top sheet 2 constitutes the skin facing surface of the absorbent article 1. On the other hand, the back sheet 3 has liquid impermeability or liquid impermeability. One surface of the back sheet 3 constitutes a surface on the non-skin facing surface side of the absorbent article 1 directed to the clothing side. The top sheet 2, the back sheet 3, and the absorbent body 4 each have a shape that is long in the same direction as the longitudinal direction of the absorbent article 1.

  An adhesive layer 10 may be provided on the surface of the absorbent article 1 on the back sheet 3 side (non-skin facing surface) depending on the specific application of the absorbent article 1. The pressure-sensitive adhesive layer 10 is used to fix the absorbent article 1 to underwear or another absorbent article when the absorbent article 1 is worn.

  The absorber 4 is sandwiched and fixed between the top sheet 2 and the back sheet 3. Both side portions along the longitudinal direction of the top sheet 2 are wound down to the non-skin facing surface side of the absorbent body 4 and are joined to the absorbent body 4 and / or the back sheet 3 between the absorbent body 4 and the back sheet 3. ing.

  The absorbent body 4 is configured by covering the absorbent core 40 with a liquid-permeable covering sheet 44 made of tissue paper or a water-permeable nonwoven fabric. The covering sheet 44 preferably covers the entire skin facing surface of the absorbent core 40. Moreover, it is preferable that the coating sheet 44 also covers the entire area of the non-skin facing surface of the absorbent core 40. Furthermore, it is preferable that the covering sheet 44 also covers the entire area of the left and right side surfaces of the absorbent core 40. In the embodiment shown in FIG. 1, one covering sheet 44 is used, and the covering sheet 44 covers the skin facing surface, the non-skin facing surface, and both side surfaces of the absorbent core 40. The covering sheet 44 covers the absorbent core 40 so that the left and right side edge regions overlap each other to form an overlapping portion 44A. In the embodiment shown in FIG. 1, the overlapping portion 44 </ b> A is formed on the non-skin facing surface of the absorbent core 40.

  The absorbent body 4 has a space 46 defined between the side surface 40S of the absorbent core 40 and the covering sheet 44 so as to be separated from each other. This space 46 exists in the state before wearing of the absorbent article 1, and preferably also exists in the wearing state of the absorbent article 1. In the state before the absorbent article 1 is worn, the distance between the side surface 40S of the absorbent core 40 and the covering sheet 44 is preferably 1 mm or more, more preferably 2 mm or more, and 3 mm or more. More preferably it is. Further, it is preferably 10 mm or less, more preferably 7 mm or less, and even more preferably 5 mm or less. Specifically, in the state before the absorbent article 1 is worn, the distance between the side surface 40S of the absorbent core 40 and the covering sheet 44 is preferably 1 mm or more and 10 mm or less, and preferably 2 mm or more and 7 mm or less. More preferably, it is more preferably 3 mm or more and 5 mm or less.

  An adhesive (not shown) such as a hot-melt pressure-sensitive adhesive is applied between the covering sheet 44 and the surface sheet 2 of the absorbent body 4 in a pattern such as dots, spirals or stripes. Are joined together. Similarly, an adhesive (not shown) is applied between the cover sheet 44 and the back sheet 3 in the absorbent body 4, thereby bonding them together.

  As shown in FIG. 1, the absorbent article 1 includes a pair of three-dimensional gathers 5 and 5 that stand on the wearer side on both sides along the longitudinal direction. The three-dimensional gathers 5 are arranged on both sides of the absorbent body 4 covered with the top sheet 2. Specifically, a pair of water-repellent sheets 6 and 6 for forming a three-dimensional gather having a constant width is disposed on each of both side portions along the longitudinal direction of the absorbent article 1 over substantially the entire length in the longitudinal direction. Yes. Each water-repellent sheet 6 is folded in two so that a bent portion extending along the longitudinal direction is formed. The water-repellent sheet 6 folded in two has two side edges extending along the longitudinal direction thereof, disposed on the back side of the absorbent body 4 together with the top sheet 2, and joined to the back sheet 3 together with the top sheet 2. Thereby, the fixed end portion 53 of the three-dimensional gather 5 is formed. The free end 62 of the three-dimensional gather 5 is composed of a bent portion of the water-repellent sheet 6 folded in half. The free end 62 side of the three-dimensional gather 5 is folded back toward the outside in the width direction Y along the longitudinal direction. Thereby, the free end part 62 of the three-dimensional gather 5 sees the outer side of the width direction Y, ie, the side edge 1a side of the absorbent article 1, seeing from the centerline (not shown) extended in the longitudinal direction of the absorbent article 1. Come to face.

  In the vicinity of the free end 62 of the three-dimensional gather 5, one or a plurality of elastic members 61 (two in FIG. 1) are arranged to extend in the longitudinal direction. The elastic member 61 is fixed to the water repellent sheet 6 in an extended state. The elastic member 61 is provided over substantially the entire length of the three-dimensional gather 5 in the longitudinal direction.

  The absorbent article 1 has a pressing groove 7 formed in the center region in the longitudinal direction with the skin facing surface side being recessed. The compressed grooves 7 extend in the longitudinal direction of the absorbent article 1, and are arranged one by one on both sides of a center line (not shown) that bisects the absorbent article 1 into left and right. Each pressing groove 7 extends along the longitudinal direction of the absorbent article 1. In the expression of extending along the longitudinal direction, in addition to the case where the compressed groove 7 extends linearly, the compressed groove 7 has an arc shape or other shape, but generally extends in the longitudinal direction. It is also included. The pressing grooves 7 and 7 have a symmetrical shape with respect to the center line. The pressing groove 7 can be formed, for example, in a gentle curved shape (arc shape) that is convex from the outside in the width direction Y toward the center line side. In this case, it is preferable that the position where the compressed grooves 7 and 7 are closest to each other is a central position or a position in the vicinity thereof among positions along the longitudinal direction of the absorbent article 1.

  The pressing grooves 7, 7 can be formed according to a conventional method by embossing such as embossing with or without heat, or ultrasonic embossing. For example, in the manufacturing process of the absorbent article 1, after supplying the topsheet 2 on one surface of the absorbent body 4, a predetermined portion is pushed in a concave shape from the topsheet 2 side to the absorbent body 4 side by embossing (squeezing) Thus, the compressed groove 7 can be formed in the predetermined portion. By forming the compressed groove 7 in this manner, in the compressed groove 7, both the topsheet 2 and the absorbent body 4 are recessed in the compressed groove 7. In the pressing groove 7, the top sheet 2 and the absorber 4 are integrated by pressing and an adhesive. The pressing groove 7 includes a large number of deep depressions (relatively deep depressions, high embossing parts) such as rectangles, squares, rhombuses, circles, and crosses in plan view, and shallow depressions (relatively shallow depressions). Or a low embossed portion) may be alternately connected to form a continuous line as a whole, or a large number of depressions may be intermittently arranged.

  FIG. 2 shows a perspective view of the absorbent core 40 in the absorbent body 4 of the absorbent article 1 shown in FIG. The absorbent core 40 shown in the figure is turned upside down and its non-skin facing surface is directed to the upper surface. FIG. 3 shows a cross-sectional view of the absorbent core 40 in the width direction. As shown in FIG. 3, the absorbent core 40 has a first surface 40A and a second surface 40B. 40A of 1st surfaces are skin opposing surfaces, and have faced the surface sheet 2 or the intermediate sheet (not shown) side used as needed. The second surface 40B is the non-skin facing surface side and faces the back sheet 3 side.

  As shown in FIGS. 2 and 3, the absorbent core 40 is adjacent to the high basis weight portion 41 and the high basis weight portion 41 having a relatively high basis weight and a convex shape protruding toward the back sheet 3 side. And a low basis weight portion 42 having a relatively low basis weight and recessed from the back sheet 3 side toward the top sheet 2 side. The high basis weight portion 41 and the low basis weight portion 42 are integrally formed. The absorbent core 40 has an uneven structure on the non-skin facing surface side, and the skin facing surface side is a flat surface. When the non-skin facing surface side of the absorbent core 40 has an uneven structure, the absorbent core 40 is easily deformed flexibly by an external force applied from the width direction of the absorbent core 40. As a result, the fit of the absorbent article 1 is improved. “Integrally molded” means that these parts are integrated without being separated from each other without using a bonding means such as an adhesive or heat fusion, and are integrally formed from the same material. Means that When these parts are integrally molded, the body fluid has continuity that can move smoothly. A manufacturing method of the absorbent core 40 having such a structure is described in, for example, Japanese Patent Application Laid-Open No. 2013-255567.

  The absorptive core 40 is comprised from the liquid absorptive material. As the liquid-absorbing material, the same materials as those conventionally used in the technical field of absorbent articles can be used. For example, various fiber materials as the liquid-absorbing material, specifically, natural fibers such as wood pulp, cotton and hemp; synthetic fibers made of synthetic resins such as polyethylene and polypropylene; semi-synthetic fibers such as acetate and rayon, etc. Can do. These fiber materials can be used singly or in combination of two or more. In the present invention, the absorbent core 40 contains a superabsorbent polymer made of a hydrogel material that has the property of absorbing water and swelling and retaining water. In particular, as shown in FIG. 3, a layer of a single pulp is formed on the most non-skin facing surface side, that is, the surface of the tip of the high basis weight portion 41 is composed only of pulp, and is a highly absorbent polymer. It is preferable to have a polymer non-existing region 43 that is absent. It is preferable to have the polymer non-existing region 43 on the tip surface of the high basis weight portion 41 because the hardness due to the superabsorbent polymer can be reduced on the non-skin facing surface of the diaper 10. The polymer non-existing region 43 is preferably present on the entire convex surface of the high basis weight portion 41 and the tip surface of the low basis weight portion 42, that is, the entire surface of the uneven structure of the non-skin facing surface. For the same reason, it is preferable that the skin-facing surface, which is a flat surface in the absorbent core 40, also has a polymer non-existing region 45 that is made of only pulp and in which no superabsorbent polymer is present. Furthermore, for the same reason, it is preferable that both side surfaces of the absorbent core 40 have a polymer non-existing region which is composed of only pulp and in which no superabsorbent polymer is present. In short, the absorbent core 40 preferably has a polymer non-existing region over the entire surface thereof. The thickness of the polymer non-existing region is preferably 0.1 mm or more and 1 mm or less inward from the surface. Further, the thickness of the polymer non-existing region in the convex portion of the absorbent core 40 is preferably 0.1 mm or more, more preferably 0.3 mm or more, and preferably 2 mm or less, more preferably 1 mm or less. A manufacturing method of the absorbent core 40 having such a structure is described in, for example, Japanese Patent Application Laid-Open No. 2013-255567.

  As shown in FIG. 2, the plurality of low basis weight portions 42 extend in parallel with the longitudinal direction X of the absorbent core 40. The low basis weight portion 42 has a plurality of the low basis weight portions 42 extending in parallel with the width direction Y of the absorbent core 40. As a result, the low basis weight portion 42 has an orthogonal lattice shape extending in the longitudinal direction and the width direction of the absorbent core 40. And the high basic weight part 41 is located in the lattice formed by the low basic weight part 42. Therefore, each high basic weight part 41 is divided by the low basic weight part 42, and is independent independently. The shapes of the respective high basis weight portions 41 are substantially the same, are rectangular in plan view, and the length in the longitudinal direction X is larger than the length in the width direction Y. On the other hand, regarding the low basic weight part 42, the low basic weight part 42 extends in the longitudinal direction X and the width direction Y of the absorbent core 40 and is connected to each other to form a continuous body. The width of the low basis weight portion 42 extending in the longitudinal direction X of the absorbent core 40 and the width of the low basis weight portion 42 extending in the width direction Y of the absorbent core 40 may be the same or different. Good.

  As described above, the absorbent core 40 has a block structure including a plurality of high basis weight portions 41 having a relatively high basis weight and low basis weight portions 42 having a relatively low basis weight, and The periphery of each high basis weight portion 41 is surrounded by the low basis weight portion 42 over the entire area to form an independent block structure. Further, the outermost periphery of the block structure is surrounded by the low basis weight portion 42. The corners of the low basis weight portion 42 located at the outermost periphery of the block structure are preferably rounded to draw a convex curve toward the outside. The block structure including the high basis weight portion 41 and the low basis weight portion 42 is formed over the entire area in the longitudinal direction X and the entire width direction Y of the absorbent core 40.

  By having a block structure composed of the high basis weight portion 41 and the low basis weight portion 42, the absorbent core 40 becomes flexible in both the longitudinal direction X and the width direction Y, and is absorbed due to that. The sex core 40 tends to follow the shape of the wearer's body. Furthermore, the excreted liquid flows while being guided by the low-thickness portion having a small thickness, so that the diffusibility in the longitudinal direction and the width direction of the absorbent core 40 can be improved.

The lower limit of the basis weight of the low basis weight portion 42 relative to the basis weight of the high basis weight portion 41 is preferably 20% or more, and more preferably 30% or more. The upper limit is preferably 80% or less, and more preferably 70% or less. The lower limit of the basis weight of the high basis weight portion 41 itself is preferably 300 g / m ² or more, and more preferably 350 g / m ² or more. The upper limit is preferably 900 g / m ² or less, more preferably 800 g / m ² or less. Regarding the low basic weight part 42, the lower limit of the basic weight is preferably 100 g / m ² or more, and more preferably 150 g / m ² or more. The upper limit is preferably 500 g / m ² or less, more preferably 400 g / m ² or less. The basis weight is measured according to the method described in paragraph [0027] of JP2013-255567A.

  The high basis weight portion 41 not only has a larger basis weight than the low basis weight portion 42 but also has a larger thickness. The lower limit of the thickness of the low basis weight portion 42 relative to the thickness of the high basis weight portion 41 is preferably 30% or more, and more preferably 40% or more. The upper limit is preferably 90% or less, and more preferably 80% or less. The lower limit of the thickness of the high basis weight portion 41 itself is preferably 2 mm or more, and more preferably 3 mm or more. The upper limit is preferably 8 mm or less, more preferably 7 mm or less. Regarding the low basis weight part 42, the lower limit of the thickness is preferably 1.5 mm or more, and more preferably 2.5 mm or more. The upper limit is preferably 4.5 mm or less, and more preferably 4 mm or less. The thickness of the high basic weight part 41 and the low basic weight part 42 (longitudinal direction X, width direction Y) is measured according to the method of Paragraph [0028] of Unexamined-Japanese-Patent No. 2013-255567.

  Due to the difference between the thickness of the high basis weight portion 41 and the thickness of the low basis weight portion 42, the plurality of convex portions 51 formed of the high basis weight portion 41 on the non-skin facing surface of the absorbent core 40. And the concavo-convex structure which consists of the recessed parts 52X and 52Y which consist of the low basic weight parts 42 is formed. And as shown in FIG. 2, the edge part of the recessed part 52X extended in the longitudinal direction X of the absorbent core 40 has reached the edge 40Y in the longitudinal direction X of the absorbent core 40. As shown in FIG. Further, the end of the recess 52 </ b> Y extending in the width direction Y reaches the side edge 40 </ b> X in the width direction Y of the absorbent core 40.

  The superabsorbent polymer contained in the absorbent core 40 preferably contains an antibacterial agent. That is, it is preferable to impart an antibacterial action to the superabsorbent polymer. Since the superabsorbent polymer has an antibacterial action, when the superabsorbent polymer absorbs and retains excrement such as urine, the excrement is less likely to rot, so that it is possible to suppress the generation of odor. Is played. In particular, as described above, the presence of the polymer non-existing regions 43 and 45 on the surface of the absorbent core 40, that is, the presence of the superabsorbent polymer inside the absorbent core 40, thereby the superabsorbent polymer. Can further suppress the generation of odor from the excrement held by the.

  The antibacterial agent used in the present invention is not particularly limited, but a hydrophobic antibacterial agent is preferably used from the viewpoint of imparting a long-lasting and continuous antibacterial action to the superabsorbent polymer. Examples of hydrophobic antibacterial agents include hydroxamic acid derivatives such as piroctone olamine (also known as piroctone ethanolamine), pyridone carboxylic acid derivatives such as pyromido acid, pipemidic acid and sinoxacin, and quaternary ammonium compounds such as benzalkonium cetyl phosphate These can be used alone or in combination of two or more. Examples of the method of adding an antibacterial agent to the superabsorbent polymer include a method of adhering antibacterial fine particles described in JP-A-2006-104119 to the superabsorbent polymer.

  In the absorbent article 1, the superabsorbent polymer contained in the absorbent core 40 contains an antibacterial agent, and the covering sheet 44 that covers the absorbent core 40 contains a fragrance. In other words, the fragrance is arranged outside the superabsorbent polymer that is the source of odor. By arranging the fragrance in this way, the fragrance reaches the wearer and the surrounding person before the odor generated from the excrement held in the superabsorbent polymer reaches the wearer and the surrounding person. Therefore, the effect of suppressing odor caused by the fragrance becomes remarkable.

  In particular, the covering sheet 44 is composed of a single sheet as shown in FIG. 1 and covers the absorbent core 40 so that the left and right side edge regions of the single covering sheet 44 overlap each other to form an overlapping portion 44A. If it does, since a fragrance arises from the whole absorber 4, the suppression effect of the odor resulting from a fragrance | flavor will become still more remarkable. From this viewpoint, it is preferable that the covering sheet 44 includes a fragrance throughout the entire area. That the fragrance is included in the entire area of the covering sheet 44 is not only the case where the fragrance is continuously included in the covering sheet 44 without a gap, but the fragrance is included discontinuously, but macroscopically The case where the fragrance | flavor is contained uniformly over the whole region of the coating sheet 44 is also included. Such a case includes, for example, a case where a fragrance is contained in a dotted, striped, spiral, or checkered pattern over the entire area of the covering sheet 44.

  Moreover, when the fragrance | flavor is contained in the whole area | region of the coating sheet 44 which has coat | covered the absorptive core 40, a fragrance | flavor should be contained in the surface sheet 2 side and the back surface sheet 3 side of the coating sheet 44 which comprises the absorber 4. become. By containing a fragrance | flavor in the surface sheet 2 side of the coating sheet 44, the suppression effect of the smell of the excretion produced from the surface sheet 2 side which is a side which excrement permeate | transmits can be made remarkable. Moreover, the fragrance | flavor is contained in the back sheet 3 side of the coating sheet 44, The suppression effect of the smell of excrement from the back sheet 3 side can also be made remarkable.

  By the way, it is known that the superabsorbent polymer has a deodorizing effect. For this reason, when the fragrance | flavor exists in the vicinity of a superabsorbent polymer, since the fragrance | flavor of this fragrance | flavor will be absorbed by the superabsorbent polymer, the suppression effect of the odor resulting from a fragrance | flavor may be attenuated. However, in this embodiment, since the fragrance is contained in the covering sheet 44 that is a member that covers the absorbent core 40 that is a member in which the superabsorbent polymer exists, the fragrance is changed to the superabsorbent polymer. It has the advantage that it is difficult to be absorbed and the aroma lasts for a long time.

  In the absorbent article 1, the covering sheet 44 and the top sheet 2 are fixed with an adhesive such as a hot melt adhesive, and the covering sheet 44 and the back sheet 3 are adhesive such as a hot melt adhesive. It is fixed with. Thus, since the adhesive such as a hot melt pressure-sensitive adhesive is interposed between the cover sheet 44 and the top sheet 2 and the back sheet 3, the cover sheet 44 is in direct contact with the top sheet 2 and the back sheet 3. Is blocked. As a result, the fragrance contained in the covering sheet 44 is effectively prevented from unintentionally shifting to the top sheet 2 and the back sheet 3. Thereby, the effect of suppressing the odor due to the fragrance contained in the covering sheet 44 becomes even more remarkable. In addition, in the absorbent body 4, the absorbent core 40 and the covering sheet 44 are not joined by an adhesive such as a hot-melt pressure-sensitive adhesive, and both are in a non-joined state. The fragrance | flavor currently made is easy to transfer to the absorptive core 40. FIG. This also makes the effect of suppressing odor due to the fragrance contained in the covering sheet 44 even more remarkable.

  Further, in the absorbent article 1, since the space 46 exists between the side surface 40 </ b> S of the absorbent core 40 and the covering sheet 44, the perfume contained in the covering sheet 44 is absorbed by the space 46. It can be easily diffused over the entire length of the body 4. This also makes the effect of suppressing odor due to the fragrance contained in the covering sheet 44 even more remarkable. When this space 46 is maintained even when the absorbent article 1 is worn, the effect of suppressing odor by the fragrance becomes extremely remarkable.

  As a method for adding a fragrance to the covering sheet 44, for example, a fragrance used is diluted in an appropriate solvent (for example, water, ethanol, low molecular hydrocarbons, polyhydric alcohols, liquid LPG gas, dimethyl ether, etc.). Or a method of coating the coating sheet 44 by applying, spraying or impregnating the coating solution 44.

  The fragrance used in the present invention is not particularly limited as long as the fragrance can be evaporated into the atmosphere at atmospheric pressure, and a normal fragrance that can perceive the fragrance in an environment of normal temperature and pressure is used without particular limitation. The same ones that have been conventionally used in the technical field can be used. For example, as the fragrance, a highly volatile fragrance component having a boiling point of about 250 ° C. or less, or a medium volatile fragrance component having a boiling point of about 250 to about 300 ° C. is preferably used.

  Examples of the highly volatile perfume component include anisole, benzaldehyde, benzyl acetate, benzyl alcohol, benzyl formate, isobornyl acetate, citronellal, citronellol, citronellyl acetate, paracymene, decanal, dihydrolinalool, dihydromyrcenol, dimethylphenyl carbinol, Eucalyptol, 1-carvone, geranial, geraniol, geranyl acetate, geranyl nitrile, neryl acetate, nonyl acetate, linalool, ethyl linalool, linalyl acetate, phenylethyl alcohol, α-pinene, β-pinene, γ-pinene, α- Examples include nonone, β-ionone, γ-ionone, α-terpineol, β-terpineol, terpinyl acetate, tentalome, etc., and these can be used alone or in combination of two or more. You can.

  Examples of the moderately volatile fragrance component include amylcinnamaldehyde, methyl dihydrojasmonate, isoamyl salicylate, β-caryophyllene, cedrene, cedryl methyl ether, cinnamon alcohol, coumarin, dimethylbenzylcarbinyl acetate, isoeugenol, and γ-methyl ionone. , Heliotropin, hexyl salicylate, cis-3-hexenyl salicylate, phenylhexanol, pentalide and the like, and these can be used alone or in combination of two or more.

  As a fragrance, in addition to the above-mentioned highly volatile and medium volatile fragrance components, or in addition to these fragrance components, a fragrance containing a fragrance having a rose, lavender, jasmine, or ylang-ylang fragrance Compositions can also be used. Examples of such a fragrance composition include nerol, lavandulol, jasmar, and cyclopiden, and one of these can be used alone or two or more can be used in combination.

  In addition, the fragrance is a combination of a fragrance material composed of a plurality of fragrances (fragrance composition), such as the above-described fragrance composition alone, natural essential oil, or blended base. "Adjusted" is included. For example, a fragrance composition containing a fragrance having a rose, lavender, jasmine, or ylang ylang-like fragrance can be used as the fragrance.

  In particular, the fragrance preferably contains a substance that inhibits activation of human olfactory receptors due to urine odor components (hereinafter, this substance is also referred to as “antagonist fragrance”). The antagonist is a competitive antagonist that inhibits the action by competing for the binding site, and the antagonist fragrance is the target when the binding site is the olfactory receptor 20 as shown in FIG. When the odor molecule 21 is bound to the olfactory receptor 20 and the receptor 20 is activated to transmit odor information, the target odor molecule 21 together with other molecules 22 is transmitted as shown in FIG. By application, the other molecule 22 is used to inhibit the activation of the receptor for the target odor molecule 21 and consequently to suppress the odor recognized by the individual. . That is, by using an antagonist fragrance, it is possible to achieve odor suppression by olfactory receptor antagonism. As described above, by using the antagonist fragrance, even if the fragrance of the antagonist fragrance itself is not strong, a high urine odor suppressing effect is exhibited.

  Smell suppression by olfactory receptor antagonism is different from the means of masking the target odor by the fragrance of the fragrance, even if it is a means of using other molecules as well Is done. An example of odor suppression by olfactory receptor antagonism is the case of using a substance that inhibits activation of the olfactory receptor, such as an antagonist. Applying a substance that inhibits activation to the receptor of the odor molecule that causes a specific odor inhibits the activation of the receptor to the odor molecule, and consequently suppresses the odor perceived by the individual. can do.

  As urine odor components, p-cresol and 2-methoxy-4-vinylphenol are known as typical ones. It is preferable from the viewpoint of effective odor suppression to suppress the odor of these substances by olfactory receptor antagonism. p-Cresol and 2-methoxy-4-vinylphenol are representative of odor emitted from urine after urination or urine collection or urine that has been scattered and dried, or urine odor emitted from absorbent articles left after use It is a typical one.

  In the present specification, the “urine odor” is preferably an odor emitted from urine after urination or after urine collection. For example, the “urine odor” in the present specification may be a urine odor that is scattered and dried, or a urine odor emitted from an absorbent article that is left after use. Also preferably, the “urine odor” herein is the odor of urine treated with β-glucuronidase or an extract thereof.

  In particular, the antagonist fragrance is preferably any substance that inhibits activation of OR9Q2, OR10G4, OR10G7, OR2W1, OR4S2, OR5P3, OR1A1, OR5K1, or OR8H1 as human olfactory receptors. As a result, the activity against the urine odor component is further suppressed, and the odor finally perceived by the individual can be further suppressed. Of these olfactory receptors, by applying an antagonistic fragrance to OR9Q2, OR2W1, OR4S2, or OR5P3, the effect of suppressing odor specifically with respect to p-cresol is exhibited. In addition, by applying an antagonistic fragrance to OR10G4, OR10G7, OR1A1, OR2W1, OR5K1, OR5P3, or OR8H1, an effect of suppressing odor is exhibited specifically with respect to 2-methoxy-4-vinylphenol.

In the present invention, particularly preferred antagonist flavors include the following compounds capable of binding to OR9Q2. These compounds can be used individually by 1 type or in combination of 2 or more types.
3- (4-tert-butylphenyl) propanal (Bourgeonal)
3,7,11-trimethyldodeca-1,6,10-trien-3-ol (Nerolidol)
Methyl cedol ketone (1-[(1S, 2R, 5R, 7S) -2,6,6,8-tetramethyltriclo [5.3.1.0 ^1,5 ] undec-8-en-9-yl] etherone; Acetyledrene)
1- (2-tert-butylcyclohexyl) oxybutan-2-ol (Ambercore)
2,2,7,7-tetramethyltricyclo [6.2.1.0 ^1,6 ] undecan-5-one (iso-Longifolaneone)
2- (2- (4-Methyl-3-cyclohexen-1-yl) propyl) cyclopentanone) (Nectaryl)

In the present invention, the following compounds that can bind to OR2W1 are also preferably exemplified as antagonistic perfumes.
(3R, 3aS, 6S, 7R, 8aS)-Octahydro-6method-3,6,8,8, -tetramethyl-1H-3a, 7-methaneazole (MethylCedyl Ether)

In the present invention, the following compounds capable of binding to OR10G4 are also preferably exemplified as antagonistic fragrances.
5-methyl-2- (1-methylethyl) -phenol (Thymol)

In the present invention, the following compounds that can bind to OR10G7 are also preferably exemplified as antagonistic fragrances.
・ 2-Methylundecanal (Aldehyde C-12 MNA)
・ Benzoin Siam

  The above-mentioned OR9Q2 antagonist fragrance, OR2W1 antagonist fragrance, OR10G4 antagonist fragrance and OR10G7 antagonist fragrance have been known as fragrance materials until now. It has not been known that it has a function of selectively suppressing urine odor. In the present invention, the fragrance is preferably an antagonist fragrance containing at least one selected from the above-mentioned compounds as an active ingredient.

  Any of the above-mentioned antagonistic fragrances for the various olfactory receptors can be purchased and used ("Synthetic fragrance chemistry and product knowledge" augmented revised edition, Motokazu Into, Chemical Industry Daily, 2005) (See the March issue). For example, the OR9Q2 antagonist fragrance can be obtained from Firmenich S. et al. A. , Givaudan S., et al. A. , International Flavors & Fragrances Inc. , SIGMA-ALDRICH Corporation, Takasago International Corporation, Kao Corporation and the like. Alternatively, it is possible to produce the same substance as the commercial product or a composition containing the same by chemical synthesis.

  Moreover, in the absorbent article of this invention, content of a fragrance | flavor is not restrict | limited in particular, According to desired deodorizing performance, absorption performance, etc., it can set suitably. For example, 0.5 mg or more and 100 mg or less of fragrance | flavor can be included per absorbent article. In particular, when an antagonist fragrance is used as the fragrance, a relatively small content of about 0.1 mg or more and 50 mg or less is preferable in that a sufficient urine odor suppressing effect can be obtained.

  Absorbent articles to which the present invention is applied widely include various products used to absorb and retain human excreta. Examples include, but are not limited to, disposable diapers for baby and adults, incontinence pads for light incontinence, auxiliary pads used inside adult disposable diapers, sanitary napkins and panty liners. Absent.

  Moreover, in the said embodiment, although the polymer non-existence area | region was provided in the whole region of the surface of the absorptive core 40, the absorptive core 40 is not restricted to the thing of this structure, For example, the skin contact surface of the absorptive core 40 The polymer non-existing region may be present only in the entire region, or the polymer non-existing region may be present only in the entire region of the non-skin facing surface of the absorbent core 40.

  Furthermore, in the said embodiment, although the absorptive core 40 was coat | covered with the coating sheet 44 of 1 sheet, instead of this, even if the absorptive core 40 is coat | covered using the coating sheet of 2 sheets or more sheets. Good. In the case of using two or more coated sheets, a fragrance may be included in at least one coated sheet.

  The absorbent article 1 of the said embodiment can be manufactured with the following manufacturing methods, for example. First, the absorptive core 1 which has a superabsorbent polymer containing an antibacterial agent is manufactured. The absorbent core 1 can be manufactured by various methods known in the art. Separately, a fragrance is included in the covering sheet 44. And the absorptive core 1 is coat | covered with the coating sheet 44, and the absorber 4 is manufactured. When using one cover sheet 44 as the cover sheet 44, it is preferable to cover the absorbent core 40 so that the left and right side edge regions of the cover sheet 44 overlap each other to form an overlapping portion 44A. The absorbent article 1 can be manufactured by disposing the top sheet 2 on the skin facing surface side and the back sheet 3 on the non-skin facing surface side of the absorbent body 4 thus manufactured. As described above, the covering sheet 44 preferably includes a fragrance throughout the entire area. In order to manufacture the absorbent article 1 including the fragrance in the entire area of the covering sheet 44, it is preferable to include the step of including the fragrance in the entire area in the process of including the fragrance in the covering sheet 44.

This invention discloses the following absorbent articles further regarding embodiment mentioned above.
<1>
An absorbent article having a top sheet, a back sheet, and an absorbent body disposed between both sheets,
The absorber includes an absorbent core and a covering sheet that covers the absorbent core,
The absorbent core contains a superabsorbent polymer,
The superabsorbent polymer contains an antibacterial agent,
An absorptive article in which a fragrance is contained in the covering sheet.

<2>
The absorbent article according to <1>, wherein the absorbent core has a polymer non-existing region in which the superabsorbent polymer is absent on the surface thereof.
<3>
One sheet of the covering sheet is used, and the covering sheet covers the absorbent core so that the left and right side edge areas thereof overlap each other to form an overlapping portion, and thereby the skin of the absorbent core faces the skin. The absorbent article according to <1> or <2>, wherein the surface, the non-skin facing surface, and both side surfaces are covered with the covering sheet.
<4>
The absorbent article according to <3>, wherein the fragrance is included in the entire area of the covering sheet.
<5>
The absorbent according to any one of <1> to <4>, wherein the absorbent body has a space defined by being separated from a side surface of the absorbent core and the covering sheet. Goods.
<6>
The covering sheet covers the absorbent core so as to form an overlapping portion,
The overlapping part of the said covering sheet is an absorbent article of any one of said <1> thru | or <5> currently formed in the non-skin opposing surface in the said absorbent core.

<7>
In a state before wearing the absorbent article, the distance between the side surface of the absorbent core and the covering sheet is preferably 1 mm or more, more preferably 2 mm or more, and 3 mm or more. More preferably, it is preferably 10 mm or less, more preferably 7 mm or less, and even more preferably 5 mm or less. Specifically, in the state before the absorbent article is worn, the absorptivity <1> The distance between the side surface of the core and the covering sheet is preferably 1 mm or more and 10 mm or less, more preferably 2 mm or more and 7 mm or less, and further preferably 3 mm or more and 5 mm or less. Thru | or <6> any one of the absorbent articles.
<8>
The absorbent article according to any one of <1> to <7>, wherein the absorbent core includes a fiber material as a liquid-absorbing material.
<9>
The absorbent core has a relatively high basis weight and a high basis weight portion having a convex shape protruding toward the back sheet side;
<1> to <8> that have a low basis weight portion that is adjacent to the high basis weight portion and has a relatively low basis weight and is recessed from the back sheet side toward the top sheet 2 side. The absorbent article according to any one of the above.
<10>
The absorbent article according to <9>, wherein the high basis weight portion and the low basis weight portion of the absorbent core are integrally formed.
<11>
A plurality of the low basis weight portions extend in parallel with the longitudinal direction of the absorbent core,
A plurality of the low basis weight parts, the plurality of which extend in parallel with the width direction of the absorbent core,
The absorbent article according to <9> or <10>, wherein the low basis weight portion has an orthogonal lattice shape extending in a longitudinal direction and a width direction of the absorbent core.
<12>
The absorbent article according to any one of <9> to <11>, wherein a polymer non-existing region is provided on a front end surface of the high basis weight portion.

<13>
The absorbent article according to any one of <9> to <12>, wherein a polymer non-existing region is provided on a convex side surface of the high basis weight portion and a front end surface of the low basis weight portion.
<14>
The absorbent article according to any one of <1> to <13>, wherein the absorbent core has an uneven structure on a non-skin facing surface side.
<15>
The absorbent article according to <14>, wherein the polymer non-existing region exists in the entire surface of the uneven structure of the non-skin facing surface.
<16>
The absorbent article according to <12> or <15>, wherein a thickness of the polymer non-existing region in the absorbent core is 0.1 mm or more and 1 mm or less inward from the surface.

<17>
<1> to <16>, wherein the absorbent core has a block structure including a plurality of high basis weight parts having a relatively high basis weight and low basis weight parts having a relatively low basis weight. The absorbent article according to any one of the above.
<18>
As for the basic weight of the said low basic weight part with respect to the basic weight of the said high basic weight part, the lower limit becomes like this. Preferably it is 20% or more, More preferably, it is 30% or more, Preferably an upper limit is 80% or less. More preferably 70% or less,
The basis weight of the high basis weight part itself has a lower limit value of preferably 300 g / m ² or more, more preferably 350 g / m ² or more, and an upper limit value of preferably 900 g / m ² or less. Preferably it is 800 g / m ² or less,
The basis weight of the low basis weight portion itself has a lower limit value of preferably 100 g / m ² or more, more preferably 150 g / m ² or more, and an upper limit value of preferably 500 g / m ² or less. The absorbent article according to <17>, preferably 400 g / m ² or less.
<19>
The lower limit of the thickness of the low basis weight relative to the thickness of the high basis weight is preferably 30% or more, more preferably 40% or more, and the upper limit is preferably 90% or less. Preferably it is 80% or less,
The lower limit value of the thickness of the high basis weight part itself is preferably 2 mm or more, more preferably 3 mm or more, and the upper limit value is preferably 8 mm or less, more preferably 7 mm or less,
The lower limit of the thickness of the low basis weight part itself is preferably 1.5 mm or more, more preferably 2.5 mm or more, and the upper limit is preferably 4.5 mm or less, more preferably 4 mm or less. The absorbent article according to <17> or <18>, wherein
<20>
In the non-skin facing surface of the absorbent core, a concavo-convex structure including a plurality of convex portions made of the high basis weight portion and a concave portion made of the low basis weight portion is formed,
The end of the recess extending in the longitudinal direction of the absorbent core reaches the edge in the longitudinal direction of the absorbent core;
The absorbent article according to any one of <17> to <19>, wherein an end of a recess extending in the width direction of the absorbent core reaches a side edge in the width direction of the absorbent.
<21>
The absorbent article according to any one of <1> to <20>, wherein the covering sheet and the top sheet are fixed with an adhesive.

<22>
The absorbent article according to any one of <1> to <21>, wherein the covering sheet and the back sheet are fixed with an adhesive.
<23>
The absorbent article according to any one of <1> to <22>, wherein the absorbent core and the covering sheet are not joined by an adhesive and are not joined.
<24>
The absorbent article according to any one of <1> to <23>, wherein the fragrance contains a substance that inhibits activation of a human olfactory receptor due to a urine odor component.
<25>
The absorbent article according to <24>, wherein the fragrance contains a substance that inhibits activation of a human olfactory receptor caused by p-cresol or 2-methoxy-4-vinylphenol.
<26>
The absorbent article according to <24> or <25>, wherein the olfactory receptor is any of OR9Q2, OR10G4, OR10G7, OR2W1, OR4S2, OR5P3, OR1A1, OR5K1, and OR8H1.

<27>
The perfume is an effective ingredient selected from the group consisting of Bourgeonal, Nerolidol, Acetyledrene, Ambercore, iso-Longifoloneone, MethylCedyl Ether, Nectaryl, Thymol, Aldehyde C-12 MNA and Benzoin Siam. The absorbent article according to any one of <24> to <26>.

<28>
The method for producing an absorbent article according to <4>,
The manufacturing method of an absorbent article provided with the process of including a fragrance | flavor in the whole region of the said covering sheet.

  Hereinafter, the present invention will be described in more detail with reference to examples. However, the scope of the present invention is not limited to such examples.

[Example 1]
As an absorbent article, a light incontinence pad 50 cc size (Laurier Sara Pure Water Absorbing Napkin 50 cc) manufactured by Kao Corporation was used. The absorbent core of this absorbent article was removed, and the absorbent core having the structure shown in FIGS. 1 to 3 was disposed instead. This absorbent core was manufactured by the method described in JP2013-255567A. The absorbent core had a basis weight of 400 g / m ² and had a polymer non-existing region on the surface on the non-skin facing surface side.

As an antibacterial agent, piroctone olamine (manufactured by Clariant, trade name “Octopirox”) was used, and 1 part by mass of piroctone olamine was dissolved in 10 parts by mass of ethanol to prepare an antibacterial agent solution. This antibacterial agent solution was mixed with dry silica (manufactured by Nippon Aerosil Co., Ltd., trade name “Aerosil 200”, average primary particle size of 12 nm, average BET specific surface area of 200 m ² / g) as silica fine particles as inorganic fine particles, and 10 mass of silica. The antibacterial fine particles in which the hydrophobic antibacterial agent is adhered to the surface of the silica fine particles were obtained by dripping and mixing the antibacterial agent solution to 10 parts by mass with respect to the parts, and drying the mixture at room temperature. . Then, water-absorbing polymer particles (trade name “AQUALIC CA” manufactured by Nippon Shokubai Co., Ltd., average particle diameter of 300 μm) and the antibacterial fine particles are mixed at a ratio of 1 part by mass with respect to 100 parts by mass of the former. Then, after obtaining a superabsorbent polymer containing an antibacterial agent, an absorbent core containing this superabsorbent polymer was obtained.

  The fragrances shown in Table 1 below were used. This fragrance was applied to the entire area of the tissue paper. This tissue paper was wound around the surface of the absorbent core in the manner shown in FIG. 1 to obtain an absorbent body.

[Comparative Examples 1 and 2]
An absorptive core containing water-absorbing polymer particles (Aquaric CA) containing no antibacterial agent was used. The fragrances shown in Table 1 below were used. The amount of the fragrance applied in Comparative Example 1 was the same as in the examples.

[Comparative Example 3]
In this comparative example, the absorptive core similar to Example 1 was used except not using the fragrance.

[Evaluation]
30 g of human urine was injected into each of the absorbent bodies of Example 1 and each comparative example, and each absorbent body was stored in a sealed container and stored at 36 ° C. assuming that it was worn. Deodorant evaluation and fragrance strength evaluation were performed for each absorber thus stored.
In the deodorization evaluation, the urine odor immediately after human urine injection was used as an initial odor, and the urine odor after 12 hours of storage was assumed sensorially according to the following criteria, assuming the removal after use. The results are shown in Table 1 below.
A: No urine odor B: Some urine odor C: Some urine odor Further, the strength of the scent was evaluated organoleptically by the following criteria for each absorber immediately after human urine injection. The results are also shown in Table 1 below.
A: Aroma that is not too strong (just good) B: A slightly strong aroma C: Aroma that is too strong or unscented

  As is clear from the results shown in Table 1, according to Example 1, it was found that all the evaluations were superior to each comparative example.

Next, in Test Example 1 below, olfactory receptors that respond to urine odor components were identified.
[Test Example 1]
1) Cloning of human olfactory receptor gene The human olfactory receptor was cloned by PCR using human genomic DNA female (G1521: Promega) as a template based on the sequence information registered in GenBank. Each gene amplified by the PCR method is incorporated into a pENTR vector (Invitrogen) according to the manual, and using the NotI and AscI sites existing on the pENTR vector, NotI prepared downstream of the Flag-Rho tag sequence on the pME18S vector, Recombined into the AscI site.

2) Preparation of pME18S-human RTP1S vector The RTP1S gene (SEQ ID NO: 19) encoding RTP1S (SEQ ID NO: 20) was incorporated into the EcoRI and XhoI sites of the pME18S vector.

3) Preparation of olfactory receptor-expressing cells HEK293 cells each expressing about 400 types of human olfactory receptors were prepared. A reaction solution having the composition shown in Table 2 was prepared and allowed to stand in a clean bench for 15 minutes, and then added to each well of a 96-well plate (BD). Subsequently, HEK293 cells (3 × 10 ⁵ cells / cm ² ) were seeded in 100 μL each well, and cultured for 24 hours in an incubator maintained at 37 ° C. and 5% CO ² .

4) Luciferase assay The olfactory receptor expressed in HEK293 cells increases the amount of intracellular cAMP by coupling with endogenous Gαs and activating adenylate cyclase. For the measurement of odor response in this study, a luciferase reporter gene assay was used to monitor the increase in intracellular cAMP level as a luminescence value derived from the firefly luciferase gene (fluc2P-CRE-hygro). In addition, a renilla luciferase gene fused to the downstream of the CMV promoter (hRluc-CMV) was introduced at the same time, and used as an internal standard for correcting errors in gene transfer efficiency and cell number.
The medium was removed from the culture prepared in 3) above, and 75 μL of a solution containing an odorous substance (p-cresol 1 mM or 2-methoxy-4-vinylphenol 300 μM) prepared with CD293 medium (Invitrogen) was added. The cells were cultured for 2.5 hours in a CO ₂ incubator to fully express the luciferase gene in the cells. The activity of luciferase was measured using a Dual-Glo ^™ luciferase assay system (Promega) according to the operation manual of the product. A value obtained by dividing the luminescence value derived from firefly luciferase induced by the odor substance stimulation by the luminescence value in the cells not subjected to the odor substance stimulation was calculated as a fold increase and used as an index of the response intensity.

5) Results As a result of measuring the response to 1 mM of p-cresol for 387 types of olfactory receptors, OR2W1, OR4S2, OR5P3, and OR9Q2 showed responses (FIG. 5). The response of these olfactory receptors to p-cresol was concentration-dependent (FIG. 6). As shown in FIGS. 5 and 6, OR2W1, OR4S2, OR5P3, and OR9Q2 were found to be p-cresol receptors that respond to p-cresol. Therefore, by using an antagonistic fragrance that suppresses the p-cresol response of OR2W1, OR4S2, OR5P3, or OR9Q2 as a fragrance included in the cover sheet of the absorbent article, an absorbent article that can effectively suppress urine odor is obtained. Can do.

  Similarly, as a result of measuring the response to 300 μM 2-methoxy-4-vinylphenol for 417 types of olfactory receptors, OR1A1, OR2W1, OR5K1, OR5P3, OR8H1, OR10G4, and OR10G7 showed responses (FIG. 7). The response of these olfactory receptors to 2-methoxy-4-vinylphenol was concentration dependent (FIG. 8). As shown in FIGS. 7 and 8, OR1A1, OR2W1, OR5K1, OR5P3, OR8H1, OR10G4 and OR10G7 are 2-methoxy-4-vinylphenol receptors that respond to 2-methoxy-4-vinylphenol. Therefore, by using an antagonistic fragrance that suppresses 2-methoxy-4-vinylphenol response of OR1A1, OR2W1, OR5K1, OR5P3, OR8H1, OR10G4, or OR10G7 as a fragrance included in the coated sheet of the absorbent article, urine odor An absorbent article capable of effectively suppressing the above is obtained.

Next, the antagonist perfume based on the olfactory receptor response was evaluated by Test Example 2 below.
[Test Example 2]
1) Identification of urine odor receptor antagonist fragrance The antagonist fragrance of the olfactory receptor (urine odor receptor) that responds to the urine odor component identified in Test Example 1 was searched, and its urine odor suppression action was evaluated. As an example of the urine odor receptor, p-cresol receptor OR9Q2 was used.
A test substance was applied to OR9Q2 expressed in HEK293 cells in the same procedure as in Test Example 1 under stimulation with 100 μM of p-cresol, and the inhibitory action of the p-cresol response of the receptor by the test substance was examined. It was. The response intensity of OR9Q2 to p-cresol in the presence of the test substance was calculated as follows. For various stimulation conditions, a value fLuc / hRluc obtained by dividing the luminescence value derived from firefly luciferase by the luminescence value derived from Renilla luciferase was calculated. The fLuc / hRluc value (X) induced by odor stimulation with p-cresol alone was subtracted by the fLuc / hRluc value (Y) in cells that had not been stimulated after introduction of the same receptor, and p-cresol alone Receptor activity (XY) by stimulation was determined. Similarly, the fLuc / hRluc value (Z) by stimulation with a mixture of p-cresol and the test substance is subtracted by the fLuc / hRluc value (Y) in cells without stimulation, and the receptor at the time of addition of the test substance Activity (ZY) was determined. Next, the ratio of the receptor activity (ZY) at the time of addition of the test substance to the receptor activity (XY) by p-cresol single stimulation is calculated by the following formula, and the response intensity of the receptor by the test substance (Response%) was determined. Independent experiments were performed three times, and the average value of each experiment was obtained.
Response (%) = (Z−Y) / (XY) × 100

  As a result of the test, Nylary (2- (2- (4-methyl-3-cyclohexen-1-yl) propyl) cyclopentanone) and Bourgeonal (3- (4-tert-butylphenyl) propionaldehyde) are OR9Q2 antagonist fragrances. It turned out that. The inhibitory effect of OR9Q2 on the p-cresol response by these substances is shown in FIG. Nectaryl and Bourgeonal both suppressed the p9-cresol response of OR9Q2 at various concentrations. Therefore, by using Nectaryl or Bourgeonal as the fragrance contained in the cover sheet of the absorbent article, it is possible to suppress the response of OR9Q2 due to the urine odor generated from the absorbent article, thereby effectively suppressing the urine odor. Can do.

2) Urinary odor suppression ability by antagonist fragrance The urine odor suppression effect by the antagonist fragrances Bourgeonal and Nectaryl identified in 1) above was confirmed by a sensory test.
A urine extract treated with β-glucuronidase was prepared as a urine odor component. The human urine stock solution was treated with β-glucuronidase at 37 ° C. for 2 hours, then adjusted to about pH 4 with hydrochloric acid, and extracted with dichloromethane. A sodium hydroxide aqueous solution was added to the obtained dichloromethane phase, and the acidic component was transferred to the aqueous phase and extracted to remove the neutral component. The obtained aqueous phase was acidified with hydrochloric acid, re-extracted with diethyl ether, and concentrated to obtain an extract. An extract equivalent to 80 mL of the urine stock solution was dissolved in 1 mL of ethanol to obtain a urine extract. The urine extract diluted with mineral oil to 1.25% by volume was used as the urine odor component.
Bourgeonal or Nectaryl was dissolved in mineral oil (Sigma) to prepare a 1% (v / v) solution, which was used as a test substance solution.
Place two cotton balls in a 20 mL glass bottle (Marem, No. 6), one cotton ball is impregnated with 30 μL of urine odor component, and the other cotton ball is one of the test substance solutions of either Bourgeonal or Nectaryl 30 μL was impregnated. The glass bottle containing the cotton ball was covered and allowed to stand at 37 ° C. for 1 hour, and then used as a odor sample in the sensory test. Only a urine odor component was prepared as a reference sample, and only mineral oil (Vehicle) was prepared as a control sample.

The sensory test was conducted in a single blind manner by 10 evaluators. The test was started from 14:00 after 1 and a half hours had passed since the meal. In order to prevent the spread of odor, the test was basically performed near the draft. In order to eliminate the effect of adaptation to odor, the cognitive strength of urine odor from urine odor components was confirmed appropriately during the test, and a break was taken if necessary. The evaluators were divided into two groups. One group was evaluated from a odor sample containing Bourgeonal, and the other group was evaluated from a odor sample containing Nectaryl, and the urine odor suppression effect of the two test substances was evaluated. The odor sample was replaced with a new one after evaluation by three evaluators.
In the evaluation of odor samples, the following five levels of criteria are set: “Odor of urine odor component: 1: I do not know 2: Can be detected 3: Easy to understand 4: Feel strong 5: Feel unbearably strong” The urine odor intensity from each odor sample when the urine odor intensity of the urine odor component alone was 3 was evaluated in 9 stages from 1.0 to 5.0 in increments of 0.5.

  The average value of the evaluation results of the sensory test by each evaluator is shown in FIG. Both the Bourgeonal and Nectaryl, which are OR9Q2 antagonist fragrances, had a statistically significant urine odor suppression effect (Wilcoxon Sinde-rank test, p <0.01). Therefore, by using Nectaryl or Bourgeonal as a fragrance contained in the cover sheet of the absorbent article, it is possible to suppress the response of OR9Q2 due to urine odor, and thus an absorbent article that can effectively suppress urine odor is obtained. .

DESCRIPTION OF SYMBOLS 1 Absorbent article 2 Top sheet 3 Back sheet 4 Absorber 5 Three-dimensional gather 6 Water-repellent sheet 7 Press groove 10 Adhesive layer 40 Absorbent core 41 High basis weight part 42 of absorbent core Low basis weight part 43 of absorbent core , 45 Polymer non-existing region 44 Cover sheet 46 Space 51 Convex part 52X, 52Y Concave part 61 Elastic member 62 Free end part of three-dimensional gather

Claims (6)

An absorbent article having a top sheet, a back sheet, and an absorbent body disposed between both sheets,
The absorber includes an absorbent core and a covering sheet that covers the absorbent core,
The absorbent core contains a superabsorbent polymer,
The superabsorbent polymer contains an antibacterial agent,
An absorptive article in which a fragrance is contained in the covering sheet.   The absorbent article according to claim 1, wherein the absorbent core has a polymer non-existing region in which the superabsorbent polymer is absent on a surface thereof.   One sheet of the covering sheet is used, and the covering sheet covers the absorbent core so that the left and right side edge areas thereof overlap each other to form an overlapping portion, and thereby the skin of the absorbent core faces the skin. The absorbent article according to claim 1 or 2, wherein the surface, the non-skin facing surface, and both side surfaces are covered with the covering sheet.   The absorptive article according to claim 3 in which said fragrance is contained in the whole field of said covering sheet.   The absorbent article according to any one of claims 1 to 4, wherein the absorbent body has a space defined by being separated from a side surface of the absorbent core and the covering sheet. It is a manufacturing method of the absorptive article according to claim 4,
The manufacturing method of an absorbent article provided with the process of including a fragrance | flavor in the whole region of the said covering sheet.

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