JP2018070582A5 - - Google Patents
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- Publication number
- JP2018070582A5 JP2018070582A5 JP2017085128A JP2017085128A JP2018070582A5 JP 2018070582 A5 JP2018070582 A5 JP 2018070582A5 JP 2017085128 A JP2017085128 A JP 2017085128A JP 2017085128 A JP2017085128 A JP 2017085128A JP 2018070582 A5 JP2018070582 A5 JP 2018070582A5
- Authority
- JP
- Japan
- Prior art keywords
- ophthalmic solution
- aqueous ophthalmic
- epinastine
- salt
- solution according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940054534 Ophthalmic Solution Drugs 0.000 claims 8
- 239000002997 ophthalmic solution Substances 0.000 claims 8
- WHWZLSFABNNENI-UHFFFAOYSA-N Epinastine Chemical compound C1C2=CC=CC=C2C2CN=C(N)N2C2=CC=CC=C21 WHWZLSFABNNENI-UHFFFAOYSA-N 0.000 claims 5
- 229960003449 epinastine Drugs 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- 239000011780 sodium chloride Substances 0.000 claims 5
- 239000007951 isotonicity adjuster Substances 0.000 claims 2
- 239000003002 pH adjusting agent Substances 0.000 claims 2
- 230000002335 preservative Effects 0.000 claims 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M buffer Substances [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 1
- 239000006172 buffering agent Substances 0.000 claims 1
- 230000003204 osmotic Effects 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
Claims (6)
- ０．０７５％（ｗ／ｖ）超の濃度のエピナスチン又はその塩、緩衝剤、等張化剤およびｐＨ調節剤のみを含有する水性点眼液であって、防腐効果を有する、水性点眼液。
- ０．１％〜５．０％（ｗ／ｖ）の濃度のエピナスチン又はその塩を含有する、請求項１記載の水性点眼液。
- マルチドーズ型容器またはユニットドーズ型容器に入れられた、請求項１または２に記載の水性点眼液。
- ｐＨが４．０〜８．０である、請求項１〜３のいずれか１項に記載の水性点眼液。
- 浸透圧比が０．５〜２．０である、請求項１〜４のいずれか１項に記載の水性点眼液。
- エピナスチン又はその塩を水性点眼液に含ませることによって防腐効力を得る方法であって、前記水性点眼液がエピナスチン又はその塩、緩衝剤、等張化剤およびｐＨ調節剤のみからなり、前記エピナスチン又はその塩の濃度が０．０７５％（ｗ／ｖ）超である、方法。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017085128A JP6635974B2 (ja) | 2017-04-24 | 2017-04-24 | エピナスチン含有点眼液 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017085128A JP6635974B2 (ja) | 2017-04-24 | 2017-04-24 | エピナスチン含有点眼液 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016211535A Division JP6134853B1 (ja) | 2016-10-28 | 2016-10-28 | エピナスチン含有点眼液 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019227272A Division JP6736752B2 (ja) | 2019-12-17 | 2019-12-17 | エピナスチン含有点眼液 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018070582A JP2018070582A (ja) | 2018-05-10 |
| JP2018070582A5 true JP2018070582A5 (ja) | 2019-12-05 |
| JP6635974B2 JP6635974B2 (ja) | 2020-01-29 |
Family
ID=62113544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017085128A Active JP6635974B2 (ja) | 2017-04-24 | 2017-04-24 | エピナスチン含有点眼液 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6635974B2 (ja) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19954516A1 (de) * | 1999-11-12 | 2001-05-17 | Boehringer Ingelheim Int | Epinastin-haltige Lösungen |
| EP2664329A1 (de) * | 2012-05-15 | 2013-11-20 | F. Holzer GmbH | Ophthalmologisches Vehikelsystem |
| WO2015125921A1 (ja) * | 2014-02-20 | 2015-08-27 | わかもと製薬株式会社 | 保存効力を有する医薬用水性組成物 |
-
2017
- 2017-04-24 JP JP2017085128A patent/JP6635974B2/ja active Active
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