JP2017537983A5 - - Google Patents
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- Publication number
- JP2017537983A5 JP2017537983A5 JP2017550461A JP2017550461A JP2017537983A5 JP 2017537983 A5 JP2017537983 A5 JP 2017537983A5 JP 2017550461 A JP2017550461 A JP 2017550461A JP 2017550461 A JP2017550461 A JP 2017550461A JP 2017537983 A5 JP2017537983 A5 JP 2017537983A5
- Authority
- JP
- Japan
- Prior art keywords
- mucoadhesive
- formulation
- concentration
- xylitol
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 13
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 13
- 235000010447 xylitol Nutrition 0.000 claims description 13
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 13
- 229960002675 xylitol Drugs 0.000 claims description 13
- 239000000811 xylitol Substances 0.000 claims description 13
- 210000002200 mouth mucosa Anatomy 0.000 claims description 8
- 230000003232 mucoadhesive effect Effects 0.000 claims 32
- 238000009472 formulation Methods 0.000 claims 26
- 239000000203 mixture Substances 0.000 claims 26
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 7
- 229920002807 Thiomer Polymers 0.000 claims 5
- 235000011187 glycerol Nutrition 0.000 claims 5
- 150000005846 sugar alcohols Chemical class 0.000 claims 5
- 239000007788 liquid Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 229920000058 polyacrylate Polymers 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 238000011065 in-situ storage Methods 0.000 claims 1
- 239000002324 mouth wash Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462089942P | 2014-12-10 | 2014-12-10 | |
| US62/089,942 | 2014-12-10 | ||
| PCT/US2015/061743 WO2016094054A1 (en) | 2014-12-10 | 2015-11-20 | Composition for the relief of dry mouth |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017537983A JP2017537983A (ja) | 2017-12-21 |
| JP2017537983A5 true JP2017537983A5 (https=) | 2018-12-06 |
| JP6783244B2 JP6783244B2 (ja) | 2020-11-11 |
Family
ID=56107939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017550461A Active JP6783244B2 (ja) | 2014-12-10 | 2015-11-20 | 口渇の軽減のための組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10772908B2 (https=) |
| EP (1) | EP3229792B1 (https=) |
| JP (1) | JP6783244B2 (https=) |
| AU (1) | AU2015361122B2 (https=) |
| CA (1) | CA2970146C (https=) |
| ES (1) | ES2982077T3 (https=) |
| MX (1) | MX388182B (https=) |
| PL (1) | PL3229792T3 (https=) |
| WO (1) | WO2016094054A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3400026A4 (en) | 2016-01-10 | 2019-08-14 | Smilesonica Inc. | VISCOSITY AND STABILITY-MODIFIED ULTRASOUND GEL |
| CN105833278B (zh) * | 2016-04-25 | 2018-05-08 | 北京嘉安医疗器械科技有限公司 | 用于治疗口腔干燥和口腔疾病的组合物 |
| AU2018225819B2 (en) | 2017-02-22 | 2023-08-10 | Smilesonica Inc. | Artificial saliva, related methods, and uses |
| US20230414463A1 (en) * | 2020-10-15 | 2023-12-28 | Advantage Silver Dental Arrest, Llc | A thickened silver diamine fluoride composition |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3970747A (en) | 1974-03-11 | 1976-07-20 | Colgate-Palmolive Company | Humectant sweetener |
| US4340583A (en) * | 1979-05-23 | 1982-07-20 | J. M. Huber Corporation | High fluoride compatibility dentifrice abrasives and compositions |
| US4997654A (en) * | 1989-08-14 | 1991-03-05 | Warner-Lambert Company | Method for increasing salivation for xerostomia patients |
| US5496558A (en) | 1993-03-02 | 1996-03-05 | Block Drug Company Inc. | Solid form xerostomia product |
| US5900230A (en) | 1997-08-18 | 1999-05-04 | Squigle, Inc. | Dental products to treat and prevent periodontal disease |
| EP1068871A1 (en) * | 1999-07-07 | 2001-01-17 | Jean-Paul Perraudin | Novel methods and medicament for treating infections diseases involving microbial biofilms |
| BRPI0514037B8 (pt) | 2004-08-02 | 2021-05-25 | Glaxo Group Ltd | composição para o cuidado oral |
| CN101945886A (zh) * | 2008-02-25 | 2011-01-12 | 西格纳姆生物科学公司 | 采用含有脂质修饰半胱氨酸的肽的局部组合物和方法 |
| US8735374B2 (en) | 2009-07-31 | 2014-05-27 | Intelgenx Corp. | Oral mucoadhesive dosage form |
| JP5433355B2 (ja) * | 2009-09-16 | 2014-03-05 | サンスター株式会社 | 口腔用組成物 |
| US8658139B1 (en) | 2010-02-27 | 2014-02-25 | Squigle, Inc. | Prevention and treatment of oral diseases |
| US20130209376A1 (en) | 2010-04-14 | 2013-08-15 | Ips Investments Inc. | Oral care compositions |
| JP5723001B2 (ja) | 2010-06-23 | 2015-05-27 | コルゲート・パーモリブ・カンパニーＣｏｌｇａｔｅ−Ｐａｌｍｏｌｉｖｅ Ｃｏｍｐａｎｙ | 治療用口腔用組成物 |
| US20120053130A1 (en) * | 2010-08-30 | 2012-03-01 | Bristol-Myers Squibb Company | Composition for enhancing absorption of a drug and method |
| WO2012083017A2 (en) | 2010-12-16 | 2012-06-21 | Celgene Corporation | Controlled release oral dosage forms of poorly soluble drugs and uses thereof |
| PH12013501155A1 (en) | 2010-12-23 | 2019-06-14 | Colgate Palmolive Co | Aqueous oral care composition comprising xanthan gum, cellulose gum and carbomer |
| EP2758037B1 (en) | 2011-09-23 | 2018-01-24 | Emerald Hilton Davis, LLC | Self-assembled nano-structure particle and method for preparing |
| WO2013089734A1 (en) * | 2011-12-15 | 2013-06-20 | Colgate-Palmolive Company | Aqueous oral care compositions |
| US9724542B2 (en) | 2012-10-12 | 2017-08-08 | Premier Dental Products Company | Remineralizing and desensitizing compositions, treatments and methods of manufacture |
-
2015
- 2015-11-20 JP JP2017550461A patent/JP6783244B2/ja active Active
- 2015-11-20 US US15/529,210 patent/US10772908B2/en active Active
- 2015-11-20 ES ES15867121T patent/ES2982077T3/es active Active
- 2015-11-20 PL PL15867121.4T patent/PL3229792T3/pl unknown
- 2015-11-20 CA CA2970146A patent/CA2970146C/en active Active
- 2015-11-20 WO PCT/US2015/061743 patent/WO2016094054A1/en not_active Ceased
- 2015-11-20 MX MX2017007597A patent/MX388182B/es unknown
- 2015-11-20 EP EP15867121.4A patent/EP3229792B1/en active Active
- 2015-11-20 AU AU2015361122A patent/AU2015361122B2/en active Active
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