JP2017536403A5 - - Google Patents
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- JP2017536403A5 JP2017536403A5 JP2017529646A JP2017529646A JP2017536403A5 JP 2017536403 A5 JP2017536403 A5 JP 2017536403A5 JP 2017529646 A JP2017529646 A JP 2017529646A JP 2017529646 A JP2017529646 A JP 2017529646A JP 2017536403 A5 JP2017536403 A5 JP 2017536403A5
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- JP
- Japan
- Prior art keywords
- tipifarnib
- administered
- hdv
- bid
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- NCDNCNXCDXHOMX-XGKFQTDJSA-N ritonavir Chemical group N([C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC=1C=CC=CC=1)NC(=O)OCC=1SC=NC=1)CC=1C=CC=CC=1)C(=O)N(C)CC1=CSC(C(C)C)=N1 NCDNCNXCDXHOMX-XGKFQTDJSA-N 0.000 claims description 50
- NCDNCNXCDXHOMX-UHFFFAOYSA-N Ritonavir Natural products C=1C=CC=CC=1CC(NC(=O)OCC=1SC=NC=1)C(O)CC(CC=1C=CC=CC=1)NC(=O)C(C(C)C)NC(=O)N(C)CC1=CSC(C(C)C)=N1 NCDNCNXCDXHOMX-UHFFFAOYSA-N 0.000 claims description 47
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- 229940095064 tartrate Drugs 0.000 description 1
- 229960001355 tenofovir disoproxil Drugs 0.000 description 1
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| US62/087,692 | 2014-12-04 | ||
| PCT/US2015/063674 WO2016090107A2 (en) | 2014-12-04 | 2015-12-03 | Treatment of hepatitis delta virus infection |
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| US10076512B2 (en) | 2014-05-01 | 2018-09-18 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| US11311519B2 (en) | 2014-05-01 | 2022-04-26 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| WO2016090107A2 (en) * | 2014-12-04 | 2016-06-09 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| WO2016172342A1 (en) | 2015-04-21 | 2016-10-27 | Eiger Biopharmaceuticals, Inc. | Pharmaceutical compositions comprising lonafarnib and ritonavir |
| JP7674628B2 (ja) | 2016-02-19 | 2025-05-12 | イーアイティー・ファーマ・インコーポレイテッド | インターフェロンラムダによるデルタ型肝炎ウイルス感染の処置 |
| WO2024223797A1 (en) * | 2023-04-28 | 2024-10-31 | Institut National de la Santé et de la Recherche Médicale | Use of cyp3a4 inhibitors for the treatment of hepatitis d virus (hdv) infections |
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| US20030181355A1 (en) * | 1992-05-29 | 2003-09-25 | Glenn Jeffrey S. | Method for inhibition of viral infection |
| AU6605196A (en) * | 1996-02-29 | 1997-09-16 | Duke University | Method of treating hepatitis delta virus infection |
| DK1140935T3 (da) * | 1998-12-23 | 2003-09-01 | Janssen Pharmaceutica Nv | 1,2-anellerede quinolinderivater |
| IL151981A0 (en) * | 2000-03-29 | 2003-04-10 | Univ Georgetown | Method of treating hepatitis delta viral infection |
| JO2361B1 (en) * | 2000-06-22 | 2006-12-12 | جانسين فارماسيوتيكا ان. في | Enaniumer 1,2-anylated quinoline inhibitor for the transporter - farnesyl |
| ES2403060T3 (es) * | 2004-11-05 | 2013-05-13 | Janssen Pharmaceutica Nv | Uso terapéutico de inhibidores de la farnesiltransferasa y métodos de control de la eficacia de los mismos. |
| WO2011088126A2 (en) * | 2010-01-13 | 2011-07-21 | Eiger Biopharmaceuticals, Inc. | Treatment of viral infection with prenyltransferase inhibitors |
| TW201247216A (en) * | 2011-04-01 | 2012-12-01 | Novartis Ag | Treatment for infection with Hepatitis B virus alone or in combination with Hepatitis delta virus and associated liver diseases |
| BR112013032381B1 (pt) * | 2011-06-14 | 2021-01-12 | Globeimmune, Inc. | composições à base de levedura e métodos para o tratamento ou prevenção de infecção pelo vírus da hepatite delta |
| SE1450131A1 (sv) * | 2011-10-21 | 2014-05-07 | Abbvie Inc | DAA-kombinationsbehandling (t.ex. med ABT-072 eller ABT-333)för användning vid behandling av HCV |
| KR20140119177A (ko) * | 2012-02-03 | 2014-10-08 | 길리애드 사이언시즈, 인코포레이티드 | 바이러스 감염의 치료에 사용하기 위한 테노포비르 알라페나미드 헤미푸마레이트 및 코비시스타트를 포함하는 조합 요법 |
| SG11201503459SA (en) * | 2012-11-02 | 2015-06-29 | Pharmacyclics Inc | Tec family kinase inhibitor adjuvant therapy |
| WO2016090107A2 (en) * | 2014-12-04 | 2016-06-09 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
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- 2015-12-03 EP EP15865819.5A patent/EP3226973A4/en not_active Withdrawn
- 2015-12-03 JP JP2017529646A patent/JP2017536403A/ja not_active Withdrawn
- 2015-12-03 US US15/531,695 patent/US20180338993A1/en not_active Abandoned
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2020
- 2020-09-11 JP JP2020152721A patent/JP2021006538A/ja active Pending
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2021
- 2021-03-10 US US17/197,687 patent/US20220023287A1/en not_active Abandoned
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