JP2017531446A - 細胞懸濁液中のトレハロースの使用 - Google Patents

細胞懸濁液中のトレハロースの使用 Download PDF

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Publication number
JP2017531446A
JP2017531446A JP2017536231A JP2017536231A JP2017531446A JP 2017531446 A JP2017531446 A JP 2017531446A JP 2017536231 A JP2017536231 A JP 2017536231A JP 2017536231 A JP2017536231 A JP 2017536231A JP 2017531446 A JP2017531446 A JP 2017531446A
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Prior art keywords
cell
trehalose
cells
composition
aqueous medium
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JP2017536231A
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Japanese (ja)
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JP2017531446A5 (enExample
Inventor
エリク， ジョン ウッズ，
エリク， ジョン ウッズ，
スレッド ティルバナ，
スレッド ティルバナ，
シェリー， ジェイ． ザカリアス，
シェリー， ジェイ． ザカリアス，
マシュー， ビー ウェルティー，
マシュー， ビー ウェルティー，
Original Assignee
クック・ジェネラル・バイオテクノロジー・エルエルシー
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Publication of JP2017531446A publication Critical patent/JP2017531446A/ja
Publication of JP2017531446A5 publication Critical patent/JP2017531446A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
JP2017536231A 2014-09-29 2015-09-29 細胞懸濁液中のトレハロースの使用 Pending JP2017531446A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462056842P 2014-09-29 2014-09-29
US62/056,842 2014-09-29
PCT/US2015/052950 WO2016069173A2 (en) 2014-09-29 2015-09-29 Uses of trehalose in cell suspensions

Publications (2)

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JP2017531446A true JP2017531446A (ja) 2017-10-26
JP2017531446A5 JP2017531446A5 (enExample) 2018-11-08

Family

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Family Applications (1)

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JP2017536231A Pending JP2017531446A (ja) 2014-09-29 2015-09-29 細胞懸濁液中のトレハロースの使用

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US (2) US20160089401A1 (enExample)
EP (1) EP3201319A4 (enExample)
JP (1) JP2017531446A (enExample)
CN (1) CN107106488A (enExample)
AU (1) AU2015339886B2 (enExample)
BR (1) BR112017006533A2 (enExample)
CA (1) CA2962239C (enExample)
WO (1) WO2016069173A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12497594B2 (en) 2020-05-08 2025-12-16 Gallant Pet, Inc. Uterine-derived regenerative cell compositions and uses thereof

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EP3525806B1 (en) * 2016-10-12 2023-02-15 Agency For Science, Technology And Research Method for lyophilising an exosome
GB201716729D0 (en) * 2017-10-12 2017-11-29 Asymptote Ltd Cryopreservation method and apparatus
US11697799B2 (en) 2019-04-15 2023-07-11 Ossium Health, Inc. System and method for extraction and cryopreservation of bone marrow
CN111856022A (zh) * 2020-07-01 2020-10-30 山东凯歌智能机器有限公司 一种检测胰腺癌患者外周血循环肿瘤细胞E-Cadherin表达的试剂盒及检测方法
CN111638341A (zh) * 2020-07-01 2020-09-08 山东凯歌智能机器有限公司 一种检测小细胞肺癌患者外周血循环肿瘤细胞pd-l1基因突变的试剂盒及检测方法
EP4181675A4 (en) 2020-07-18 2024-04-24 Ossium Health, Inc. PERMEATION OF WHOLE VERTEBRATE BODIES WITH A CRYOPRETECTIVE AGENT USING VACUUM-ASSISTED DIFFUSION
CA3195653A1 (en) 2020-10-14 2022-04-21 Ossium Health, Inc. Systems and methods for extraction and cryopreservation of bone marrow
WO2022133282A1 (en) 2020-12-18 2022-06-23 Ossium Health, Inc. Methods of cell therapies
US20240060049A1 (en) 2020-12-19 2024-02-22 Habil F KHORAKIWALA Lyophilized mesenchymal stem cells

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012500021A (ja) * 2008-08-20 2012-01-05 アンスロジェネシス コーポレーション 改良型細胞組成物およびその作製方法
JP2012115253A (ja) * 2010-11-09 2012-06-21 Otsuka Pharmaceut Factory Inc 幹細胞懸濁液
JP2013233102A (ja) * 2012-05-08 2013-11-21 Otsuka Pharmaceut Factory Inc トレハロース含有肺塞栓形成予防用哺乳動物細胞懸濁液

Family Cites Families (11)

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ES2194911T3 (es) * 1994-06-02 2003-12-01 Elan Drug Delivery Ltd Metodo para evitar la agregacion de proteinas/peptidos cuando tiene lugar su rehidratacion o descongelacion.
DE59804785D1 (de) * 1997-11-22 2002-08-22 Roche Diagnostics Gmbh Verbessertes Verfahren zur Stabilisierung von Proteinen
US20060134596A1 (en) * 2003-05-08 2006-06-22 Anita Sjogren Cryopreservation of human blastocyst-derived stem cells by use of a closed straw vitrification method
EP1841856A1 (en) * 2005-01-28 2007-10-10 Canadian Blood Services A method of cryopreserving cells and tissues by liposomal delivery of sugars to enhance post-thaw viability
CA2635978A1 (en) * 2006-01-04 2007-07-12 Do-Coop Technologies Ltd. Solid-fluid composition
JP5940975B2 (ja) * 2009-07-20 2016-06-29 ザ ジェネラル ホスピタル コーポレーション ディー／ビー／エイ マサチューセッツ ジェネラル ホスピタル 凍結保存細胞の生存率を向上させるための方法および組成物
CN103180435A (zh) * 2010-08-31 2013-06-26 库克通用生物技术有限责任公司 用于治疗动物疾病的全身的同种异体干细胞疗法
MX370199B (es) * 2012-02-16 2019-12-05 Santarus Inc Composiciones farmaceuticas de anticuerpo anti-antigeno muy tardio (cd49a).
JP5196618B1 (ja) * 2012-09-28 2013-05-15 株式会社大塚製薬工場 トレハロース含有細胞洗浄溶液を用いた接着細胞の洗浄方法
CN104161037B (zh) * 2014-08-13 2016-01-13 江苏丘陵地区镇江农业科学研究所 一种山羊精液玻璃化冷冻和解冻配方与方法
CN105052894B (zh) * 2015-08-26 2018-03-06 中国农业科学院特产研究所 一种gv期卵母细胞冷冻保存液及冷冻保存方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012500021A (ja) * 2008-08-20 2012-01-05 アンスロジェネシス コーポレーション 改良型細胞組成物およびその作製方法
JP2012115253A (ja) * 2010-11-09 2012-06-21 Otsuka Pharmaceut Factory Inc 幹細胞懸濁液
JP2013233102A (ja) * 2012-05-08 2013-11-21 Otsuka Pharmaceut Factory Inc トレハロース含有肺塞栓形成予防用哺乳動物細胞懸濁液

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12497594B2 (en) 2020-05-08 2025-12-16 Gallant Pet, Inc. Uterine-derived regenerative cell compositions and uses thereof

Also Published As

Publication number Publication date
US20160089401A1 (en) 2016-03-31
WO2016069173A3 (en) 2016-07-28
BR112017006533A2 (pt) 2017-12-19
CA2962239A1 (en) 2016-05-06
EP3201319A2 (en) 2017-08-09
US20210252155A1 (en) 2021-08-19
CN107106488A (zh) 2017-08-29
AU2015339886A1 (en) 2017-04-13
AU2015339886B2 (en) 2019-05-09
EP3201319A4 (en) 2018-05-16
WO2016069173A2 (en) 2016-05-06
CA2962239C (en) 2024-01-02

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