AU2015339886B2 - Uses of trehalose in cell suspensions - Google Patents

Uses of trehalose in cell suspensions Download PDF

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Publication number
AU2015339886B2
AU2015339886B2 AU2015339886A AU2015339886A AU2015339886B2 AU 2015339886 B2 AU2015339886 B2 AU 2015339886B2 AU 2015339886 A AU2015339886 A AU 2015339886A AU 2015339886 A AU2015339886 A AU 2015339886A AU 2015339886 B2 AU2015339886 B2 AU 2015339886B2
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AU
Australia
Prior art keywords
trehalose
cells
liquid medium
aqueous liquid
cell suspension
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Active
Application number
AU2015339886A
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English (en)
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AU2015339886A1 (en
Inventor
Sreedhar Thirumala
Matthew B. Welty
Erik John Woods
Shelly J. Zacharias
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Cook General Biotechnolgy LLC
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Cook General Biotechnolgy LLC
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Publication of AU2015339886A1 publication Critical patent/AU2015339886A1/en
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Publication of AU2015339886B2 publication Critical patent/AU2015339886B2/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
AU2015339886A 2014-09-29 2015-09-29 Uses of trehalose in cell suspensions Active AU2015339886B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462056842P 2014-09-29 2014-09-29
US62/056,842 2014-09-29
PCT/US2015/052950 WO2016069173A2 (en) 2014-09-29 2015-09-29 Uses of trehalose in cell suspensions

Publications (2)

Publication Number Publication Date
AU2015339886A1 AU2015339886A1 (en) 2017-04-13
AU2015339886B2 true AU2015339886B2 (en) 2019-05-09

Family

ID=55583355

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2015339886A Active AU2015339886B2 (en) 2014-09-29 2015-09-29 Uses of trehalose in cell suspensions

Country Status (8)

Country Link
US (2) US20160089401A1 (enExample)
EP (1) EP3201319A4 (enExample)
JP (1) JP2017531446A (enExample)
CN (1) CN107106488A (enExample)
AU (1) AU2015339886B2 (enExample)
BR (1) BR112017006533A2 (enExample)
CA (1) CA2962239C (enExample)
WO (1) WO2016069173A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3525806B1 (en) * 2016-10-12 2023-02-15 Agency For Science, Technology And Research Method for lyophilising an exosome
GB201716729D0 (en) * 2017-10-12 2017-11-29 Asymptote Ltd Cryopreservation method and apparatus
US11697799B2 (en) 2019-04-15 2023-07-11 Ossium Health, Inc. System and method for extraction and cryopreservation of bone marrow
AU2021267900A1 (en) 2020-05-08 2023-01-19 Gallant Pet Inc. Uterine-derived regenerative cell compositions and uses thereof
CN111856022A (zh) * 2020-07-01 2020-10-30 山东凯歌智能机器有限公司 一种检测胰腺癌患者外周血循环肿瘤细胞E-Cadherin表达的试剂盒及检测方法
CN111638341A (zh) * 2020-07-01 2020-09-08 山东凯歌智能机器有限公司 一种检测小细胞肺癌患者外周血循环肿瘤细胞pd-l1基因突变的试剂盒及检测方法
EP4181675A4 (en) 2020-07-18 2024-04-24 Ossium Health, Inc. PERMEATION OF WHOLE VERTEBRATE BODIES WITH A CRYOPRETECTIVE AGENT USING VACUUM-ASSISTED DIFFUSION
CA3195653A1 (en) 2020-10-14 2022-04-21 Ossium Health, Inc. Systems and methods for extraction and cryopreservation of bone marrow
WO2022133282A1 (en) 2020-12-18 2022-06-23 Ossium Health, Inc. Methods of cell therapies
US20240060049A1 (en) 2020-12-19 2024-02-22 Habil F KHORAKIWALA Lyophilized mesenchymal stem cells

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050163750A1 (en) * 1994-06-02 2005-07-28 Elan Drug Delivery Limited Methods of preventing aggregation of various substances upon rehydration or thawing and compositions obtained thereby
US20140093961A1 (en) * 2012-09-28 2014-04-03 Otsuka Pharmaceutical Factory, Inc. Method of washing adherent cell using trehalose-containing cell-washing solution

Family Cites Families (12)

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DE59804785D1 (de) * 1997-11-22 2002-08-22 Roche Diagnostics Gmbh Verbessertes Verfahren zur Stabilisierung von Proteinen
US20060134596A1 (en) * 2003-05-08 2006-06-22 Anita Sjogren Cryopreservation of human blastocyst-derived stem cells by use of a closed straw vitrification method
EP1841856A1 (en) * 2005-01-28 2007-10-10 Canadian Blood Services A method of cryopreserving cells and tissues by liposomal delivery of sugars to enhance post-thaw viability
CA2635978A1 (en) * 2006-01-04 2007-07-12 Do-Coop Technologies Ltd. Solid-fluid composition
KR20240052847A (ko) * 2008-08-20 2024-04-23 셀룰래리티 인코포레이티드 개선된 세포 조성물 및 그의 제조 방법
JP5940975B2 (ja) * 2009-07-20 2016-06-29 ザ ジェネラル ホスピタル コーポレーション ディー／ビー／エイ マサチューセッツ ジェネラル ホスピタル 凍結保存細胞の生存率を向上させるための方法および組成物
CN103180435A (zh) * 2010-08-31 2013-06-26 库克通用生物技术有限责任公司 用于治疗动物疾病的全身的同种异体干细胞疗法
JP5341059B2 (ja) * 2010-11-09 2013-11-13 株式会社大塚製薬工場 幹細胞懸濁液
MX370199B (es) * 2012-02-16 2019-12-05 Santarus Inc Composiciones farmaceuticas de anticuerpo anti-antigeno muy tardio (cd49a).
JP5432322B2 (ja) * 2012-05-08 2014-03-05 株式会社大塚製薬工場 トレハロース含有肺塞栓形成予防用哺乳動物細胞懸濁液
CN104161037B (zh) * 2014-08-13 2016-01-13 江苏丘陵地区镇江农业科学研究所 一种山羊精液玻璃化冷冻和解冻配方与方法
CN105052894B (zh) * 2015-08-26 2018-03-06 中国农业科学院特产研究所 一种gv期卵母细胞冷冻保存液及冷冻保存方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050163750A1 (en) * 1994-06-02 2005-07-28 Elan Drug Delivery Limited Methods of preventing aggregation of various substances upon rehydration or thawing and compositions obtained thereby
US20140093961A1 (en) * 2012-09-28 2014-04-03 Otsuka Pharmaceutical Factory, Inc. Method of washing adherent cell using trehalose-containing cell-washing solution

Also Published As

Publication number Publication date
JP2017531446A (ja) 2017-10-26
US20160089401A1 (en) 2016-03-31
WO2016069173A3 (en) 2016-07-28
BR112017006533A2 (pt) 2017-12-19
CA2962239A1 (en) 2016-05-06
EP3201319A2 (en) 2017-08-09
US20210252155A1 (en) 2021-08-19
CN107106488A (zh) 2017-08-29
AU2015339886A1 (en) 2017-04-13
EP3201319A4 (en) 2018-05-16
WO2016069173A2 (en) 2016-05-06
CA2962239C (en) 2024-01-02

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