JP2017529062A5 - - Google Patents
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- JP2017529062A5 JP2017529062A5 JP2017502621A JP2017502621A JP2017529062A5 JP 2017529062 A5 JP2017529062 A5 JP 2017529062A5 JP 2017502621 A JP2017502621 A JP 2017502621A JP 2017502621 A JP2017502621 A JP 2017502621A JP 2017529062 A5 JP2017529062 A5 JP 2017529062A5
- Authority
- JP
- Japan
- Prior art keywords
- ligand
- rna
- stranded
- base
- complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003446 ligand Substances 0.000 claims description 102
- 238000000034 method Methods 0.000 claims description 24
- 108020004414 DNA Proteins 0.000 claims description 16
- 102000053602 DNA Human genes 0.000 claims description 13
- 108020004682 Single-Stranded DNA Proteins 0.000 claims description 9
- 239000000126 substance Substances 0.000 claims description 5
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 3
- 102000003960 Ligases Human genes 0.000 claims description 2
- 108090000364 Ligases Proteins 0.000 claims description 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 65
- 230000000295 complement effect Effects 0.000 claims 12
- 102000040650 (ribonucleotides)n+m Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108091023037 Aptamer Proteins 0.000 claims 2
- 150000001720 carbohydrates Chemical class 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 238000000926 separation method Methods 0.000 claims 2
- 239000002689 soil Substances 0.000 claims 2
- 238000004566 IR spectroscopy Methods 0.000 claims 1
- 229920002684 Sepharose Polymers 0.000 claims 1
- 238000012300 Sequence Analysis Methods 0.000 claims 1
- 229920001222 biopolymer Polymers 0.000 claims 1
- 239000000919 ceramic Substances 0.000 claims 1
- 238000004587 chromatography analysis Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000004817 gas chromatography Methods 0.000 claims 1
- 239000011521 glass Substances 0.000 claims 1
- 238000004128 high performance liquid chromatography Methods 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 238000004949 mass spectrometry Methods 0.000 claims 1
- 229920001059 synthetic polymer Polymers 0.000 claims 1
- 239000012634 fragment Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102014213783.7 | 2014-07-16 | ||
| DE102014213783.7A DE102014213783B3 (de) | 2014-07-16 | 2014-07-16 | Verfahren zur Identifizierung hochaffiner Komplexe aus zwei Liganden und einem Rezeptor, Vorrichtung zur Durchführung des Verfahrens und selbst-assemblierende chemische Bibliothek zur Verwendung in dem Verfahren |
| PCT/EP2015/065874 WO2016008822A2 (de) | 2014-07-16 | 2015-07-10 | Verfahren zur identifizierung hochaffiner komplexe aus zwei liganden und einem rezeptor, vorrichtung zur durchführung des verfahrens und selbst-assemblierende chemische bibliothek zur verwendung in dem verfahren |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021013303A Division JP7112540B2 (ja) | 2014-07-16 | 2021-01-29 | ２個のリガンドと１個のレセプタとからなる高親和性錯体の特定方法と該方法を実行する装置及び該方法に用いられる自己集合型ケミカルライブラリ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017529062A JP2017529062A (ja) | 2017-10-05 |
| JP2017529062A5 true JP2017529062A5 (OSRAM) | 2018-08-16 |
| JP6831776B2 JP6831776B2 (ja) | 2021-02-17 |
Family
ID=53192981
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017502621A Active JP6831776B2 (ja) | 2014-07-16 | 2015-07-10 | ２個のリガンドと１個のレセプタとからなる高親和性錯体の特定方法と該方法を実行する装置及び該方法に用いられる自己集合型ケミカルライブラリ |
| JP2021013303A Active JP7112540B2 (ja) | 2014-07-16 | 2021-01-29 | ２個のリガンドと１個のレセプタとからなる高親和性錯体の特定方法と該方法を実行する装置及び該方法に用いられる自己集合型ケミカルライブラリ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021013303A Active JP7112540B2 (ja) | 2014-07-16 | 2021-01-29 | ２個のリガンドと１個のレセプタとからなる高親和性錯体の特定方法と該方法を実行する装置及び該方法に用いられる自己集合型ケミカルライブラリ |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11365439B2 (OSRAM) |
| EP (2) | EP3477299B1 (OSRAM) |
| JP (2) | JP6831776B2 (OSRAM) |
| CA (1) | CA2955087C (OSRAM) |
| DE (1) | DE102014213783B3 (OSRAM) |
| DK (1) | DK3169832T3 (OSRAM) |
| ES (2) | ES2712899T3 (OSRAM) |
| WO (1) | WO2016008822A2 (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109312492B (zh) | 2016-06-16 | 2022-10-04 | 哈斯达克科学公司 | 寡核苷酸指导和记录的编码探针分子的组合合成 |
| US11795580B2 (en) | 2017-05-02 | 2023-10-24 | Haystack Sciences Corporation | Molecules for verifying oligonucleotide directed combinatorial synthesis and methods of making and using the same |
| CN107652453B (zh) * | 2017-09-26 | 2020-05-05 | 天津工业大学 | 接枝rgd短肽温敏可注射水凝胶及其制备方法和应用 |
| EP3604525B1 (en) * | 2018-08-02 | 2021-03-10 | TU Dresden | Method for providing a dna-encoded library, dna-encoded library and method of decoding a dna-encoded library |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5512439A (en) * | 1988-11-21 | 1996-04-30 | Dynal As | Oligonucleotide-linked magnetic particles and uses thereof |
| US7018793B1 (en) * | 1995-12-07 | 2006-03-28 | Diversa Corporation | Combinatorial screening of mixed populations of organisms |
| DE19619373A1 (de) * | 1996-05-14 | 1997-11-20 | Hoechst Ag | Neue Substanzbibliothek und damit hergestellte supramolekulare Komplexe |
| AU2002307152A1 (en) * | 2001-04-06 | 2002-10-21 | California Institute Of Technology | Nucleic acid amplification utilizing microfluidic devices |
| WO2003076943A1 (en) * | 2002-03-08 | 2003-09-18 | Eidgenössische Technische Hochschule Zürich | Encoded self-assembling chemical libraries (esachel) |
| EP1615948B1 (en) * | 2003-04-18 | 2015-04-01 | Becton Dickinson and Company | Immuno-amplification |
| US7229769B2 (en) * | 2005-03-25 | 2007-06-12 | Illumina, Inc. | Compositions and methods for detecting protease activity |
| ATE544870T1 (de) * | 2006-09-18 | 2012-02-15 | Ensemble Therapeutics Corp | Profilierung einer rezeptorfamilie |
| JP2009034052A (ja) * | 2007-08-02 | 2009-02-19 | Canon Inc | ハイブリダイゼーション方法および装置 |
| EP2138587A1 (en) * | 2008-06-23 | 2009-12-30 | Koninklijke Philips Electronics N.V. | Amplification of nucleic acids using temperature zones |
| CN102076870A (zh) | 2008-06-25 | 2011-05-25 | 实时基因组有限公司 | 对微阵列上的核酸进行解链曲线分析的方法和装置 |
| DK2446033T3 (da) * | 2009-06-22 | 2014-01-27 | Univ Strasbourg | Fremgangsmåde til fremstilling af et addukt |
| US10190986B2 (en) * | 2011-06-06 | 2019-01-29 | Abbott Laboratories | Spatially resolved ligand-receptor binding assays |
| BE1020816A5 (fr) | 2012-07-04 | 2014-05-06 | Coris Bioconcept Sprl | Procede et dispositif pour la detection rapide de sequences nucleotidiques amplifiees. |
| US9567632B2 (en) * | 2013-03-19 | 2017-02-14 | New England Biolabs, Inc. | Enrichment of target sequences |
-
2014
- 2014-07-16 DE DE102014213783.7A patent/DE102014213783B3/de active Active
-
2015
- 2015-07-10 ES ES15744501T patent/ES2712899T3/es active Active
- 2015-07-10 CA CA2955087A patent/CA2955087C/en active Active
- 2015-07-10 EP EP18207435.1A patent/EP3477299B1/de active Active
- 2015-07-10 US US15/326,172 patent/US11365439B2/en active Active
- 2015-07-10 EP EP15744501.6A patent/EP3169832B1/de active Active
- 2015-07-10 DK DK15744501.6T patent/DK3169832T3/en active
- 2015-07-10 ES ES18207435T patent/ES3002709T3/es active Active
- 2015-07-10 WO PCT/EP2015/065874 patent/WO2016008822A2/de not_active Ceased
- 2015-07-10 JP JP2017502621A patent/JP6831776B2/ja active Active
-
2021
- 2021-01-29 JP JP2021013303A patent/JP7112540B2/ja active Active
-
2022
- 2022-06-07 US US17/834,197 patent/US20220298552A1/en active Pending
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