JP2017525972A5 - - Google Patents
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- JP2017525972A5 JP2017525972A5 JP2017511664A JP2017511664A JP2017525972A5 JP 2017525972 A5 JP2017525972 A5 JP 2017525972A5 JP 2017511664 A JP2017511664 A JP 2017511664A JP 2017511664 A JP2017511664 A JP 2017511664A JP 2017525972 A5 JP2017525972 A5 JP 2017525972A5
- Authority
- JP
- Japan
- Prior art keywords
- globin
- glycosylated
- glucosylated
- percentage
- hemoglobin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 14
- 238000001819 mass spectrum Methods 0.000 claims 5
- 102000017011 Glycated Hemoglobin A Human genes 0.000 claims 4
- 108010014663 Glycated Hemoglobin A Proteins 0.000 claims 4
- 102100027685 Hemoglobin subunit alpha Human genes 0.000 claims 4
- 108091005902 Hemoglobin subunit alpha Proteins 0.000 claims 4
- 102100021519 Hemoglobin subunit beta Human genes 0.000 claims 4
- 108091005904 Hemoglobin subunit beta Proteins 0.000 claims 4
- 239000008280 blood Substances 0.000 claims 4
- 210000004369 blood Anatomy 0.000 claims 4
- 238000010183 spectrum analysis Methods 0.000 claims 4
- 206010018429 Glucose tolerance impaired Diseases 0.000 claims 2
- 108010054147 Hemoglobins Proteins 0.000 claims 2
- 102000001554 Hemoglobins Human genes 0.000 claims 2
- 208000001280 Prediabetic State Diseases 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- 230000013595 glycosylation Effects 0.000 claims 2
- 238000006206 glycosylation reaction Methods 0.000 claims 2
- 238000004949 mass spectrometry Methods 0.000 claims 2
- 201000009104 prediabetes syndrome Diseases 0.000 claims 2
- 238000001228 spectrum Methods 0.000 claims 2
- 238000001269 time-of-flight mass spectrometry Methods 0.000 claims 2
- 230000009089 cytolysis Effects 0.000 claims 1
- 238000003795 desorption Methods 0.000 claims 1
- 238000010790 dilution Methods 0.000 claims 1
- 239000012895 dilution Substances 0.000 claims 1
- 102000018146 globin Human genes 0.000 claims 1
- 108060003196 globin Proteins 0.000 claims 1
- 238000000050 ionisation spectroscopy Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 238000004611 spectroscopical analysis Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1415369.6A GB201415369D0 (en) | 2014-08-29 | 2014-08-29 | Rapid screening and evaluation of diabetes and prediabetes by glycated haemoglobin mass spectrometry |
| GB1415369.6 | 2014-08-29 | ||
| PCT/GB2015/052487 WO2016030687A1 (en) | 2014-08-29 | 2015-08-27 | Rapid screening and evaluation of diabetes and prediabetes by glycated hemoglobin mass spectrometry. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017525972A JP2017525972A (ja) | 2017-09-07 |
| JP2017525972A5 true JP2017525972A5 (https=) | 2018-10-04 |
Family
ID=51752373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017511664A Pending JP2017525972A (ja) | 2014-08-29 | 2015-08-27 | グルコシル化ヘモグロビン質量分析法による糖尿病および前糖尿病の迅速なスクリーニングと評価 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10161941B2 (https=) |
| EP (1) | EP3186641B1 (https=) |
| JP (1) | JP2017525972A (https=) |
| CN (1) | CN107209189B (https=) |
| GB (1) | GB201415369D0 (https=) |
| WO (1) | WO2016030687A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3695230A4 (en) * | 2017-10-09 | 2021-12-08 | Lifestory Health Inc. | SELECTION BIOMARKERS FOR PATIENT STRATIFICATION IN BODY FLUIDS AND THE APPLICATION OF PRECISION MEDICINE BY NEW DIAGNOSTIC BIOMARKERS |
| WO2019099948A1 (en) * | 2017-11-17 | 2019-05-23 | Bio-Rad Laboratories, Inc. | Smart advisor for blood test evaluation |
| CA3110444A1 (en) * | 2018-08-22 | 2020-02-27 | Quest Diagnostics Investments Llc | Microsampling detection in diabetes |
| CN110133280B (zh) * | 2019-04-29 | 2022-05-20 | 融智生物科技（青岛）有限公司 | 一种β链变异的血红蛋白糖化率的测定方法 |
| CN110658251A (zh) * | 2019-10-01 | 2020-01-07 | 长沙湘华质谱医学科技有限公司 | 表征地中海贫血症的特征蛋白组合物或质谱模型的用途 |
| CN111638261B (zh) * | 2020-04-17 | 2023-04-07 | 融智生物科技（青岛）有限公司 | 一种计算设备、存储介质和地中海贫血筛查装置及系统 |
| CN114527190A (zh) * | 2022-01-14 | 2022-05-24 | 融智生物科技（青岛）有限公司 | 一种糖化血红蛋白检测试剂盒及其检测方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4847209A (en) * | 1987-11-09 | 1989-07-11 | Miles Inc. | Latex agglutination immunoassay in the presence of hemoglobin |
| US20040171026A1 (en) * | 2001-09-05 | 2004-09-02 | Hochstrasser Denis Francois | Diagnostic method for transmissible spongiform encephalopathies |
| TW200538738A (en) * | 2004-02-20 | 2005-12-01 | Univ California | Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity |
| US20080108144A1 (en) * | 2004-05-27 | 2008-05-08 | Alam Muhammad A | Method for the Rapid Analysis of Polypeptides |
| US8309313B2 (en) * | 2006-03-06 | 2012-11-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Glycated peptides and methods of use |
| JP2007263896A (ja) * | 2006-03-29 | 2007-10-11 | Univ Nagoya | 肺癌患者の術後予後予測のための生物マーカー及びその方法 |
| US7951776B2 (en) * | 2006-09-01 | 2011-05-31 | American Type Culture Collection | Methods for treatment of type 1 diabetes |
| US9250248B2 (en) * | 2006-11-01 | 2016-02-02 | The Johns Hopkins University | Early detection of diabetes |
| WO2009117395A2 (en) * | 2008-03-17 | 2009-09-24 | Nelson Randall W | Biomarkers and assays for diabetes |
| EP2294426A1 (en) * | 2008-05-27 | 2011-03-16 | F. Hoffmann-La Roche AG | Method for risk reduction in glycemic control |
| CA2765457A1 (en) * | 2009-07-07 | 2011-01-13 | Uvic Industry Partnerships Inc. | Methods for early detection of blood disorders |
| SG195180A1 (en) | 2011-05-31 | 2013-12-30 | Singapore Health Serv Pte Ltd | Method for detecting disease biomarkers |
| WO2014118634A1 (en) * | 2013-01-31 | 2014-08-07 | Eustache Paramithiotis | Type 2 diabetes biomarkers and uses thereof |
-
2014
- 2014-08-29 GB GBGB1415369.6A patent/GB201415369D0/en not_active Ceased
-
2015
- 2015-08-27 WO PCT/GB2015/052487 patent/WO2016030687A1/en not_active Ceased
- 2015-08-27 JP JP2017511664A patent/JP2017525972A/ja active Pending
- 2015-08-27 US US15/506,731 patent/US10161941B2/en active Active
- 2015-08-27 CN CN201580046748.8A patent/CN107209189B/zh active Active
- 2015-08-27 EP EP15760506.4A patent/EP3186641B1/en active Active
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