JP2017522555A5 - - Google Patents
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- JP2017522555A5 JP2017522555A5 JP2016575349A JP2016575349A JP2017522555A5 JP 2017522555 A5 JP2017522555 A5 JP 2017522555A5 JP 2016575349 A JP2016575349 A JP 2016575349A JP 2016575349 A JP2016575349 A JP 2016575349A JP 2017522555 A5 JP2017522555 A5 JP 2017522555A5
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- JP
- Japan
- Prior art keywords
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- subject
- protein
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 102000004169 proteins and genes Human genes 0.000 claims 22
- 108090000623 proteins and genes Proteins 0.000 claims 22
- 238000000034 method Methods 0.000 claims 17
- 210000004369 blood Anatomy 0.000 claims 12
- 239000008280 blood Substances 0.000 claims 12
- 201000010915 Glioblastoma multiforme Diseases 0.000 claims 11
- 208000005017 glioblastoma Diseases 0.000 claims 11
- 102100028006 Heme oxygenase 1 Human genes 0.000 claims 10
- 101001079623 Homo sapiens Heme oxygenase 1 Proteins 0.000 claims 10
- 102100032912 CD44 antigen Human genes 0.000 claims 9
- 101000868273 Homo sapiens CD44 antigen Proteins 0.000 claims 9
- 101000894525 Homo sapiens Transforming growth factor-beta-induced protein ig-h3 Proteins 0.000 claims 9
- 102100021398 Transforming growth factor-beta-induced protein ig-h3 Human genes 0.000 claims 9
- 102100025351 C-type mannose receptor 2 Human genes 0.000 claims 7
- 101000576898 Homo sapiens C-type mannose receptor 2 Proteins 0.000 claims 7
- 101000622304 Homo sapiens Vascular cell adhesion protein 1 Proteins 0.000 claims 7
- 102100023543 Vascular cell adhesion protein 1 Human genes 0.000 claims 7
- 101000868279 Homo sapiens Leukocyte surface antigen CD47 Proteins 0.000 claims 6
- 101000590830 Homo sapiens Monocarboxylate transporter 1 Proteins 0.000 claims 6
- 102100032913 Leukocyte surface antigen CD47 Human genes 0.000 claims 6
- 102100034068 Monocarboxylate transporter 1 Human genes 0.000 claims 6
- 101000798762 Anguilla anguilla Troponin C, skeletal muscle Proteins 0.000 claims 5
- 102100029397 Chloride channel CLIC-like protein 1 Human genes 0.000 claims 5
- -1 DDR2 Proteins 0.000 claims 5
- 101000989992 Homo sapiens Chloride channel CLIC-like protein 1 Proteins 0.000 claims 5
- 101000931590 Homo sapiens Prostaglandin F2 receptor negative regulator Proteins 0.000 claims 5
- 101000666340 Homo sapiens Tenascin Proteins 0.000 claims 5
- 102100032832 Integrin alpha-7 Human genes 0.000 claims 5
- 102100020864 Prostaglandin F2 receptor negative regulator Human genes 0.000 claims 5
- 102100038126 Tenascin Human genes 0.000 claims 5
- 108010092830 integrin alpha7beta1 Proteins 0.000 claims 5
- 102100037917 CD109 antigen Human genes 0.000 claims 4
- 102100027848 Cartilage-associated protein Human genes 0.000 claims 4
- 108010072135 Cell Adhesion Molecule-1 Proteins 0.000 claims 4
- 102100024649 Cell adhesion molecule 1 Human genes 0.000 claims 4
- 101000738399 Homo sapiens CD109 antigen Proteins 0.000 claims 4
- 101000859758 Homo sapiens Cartilage-associated protein Proteins 0.000 claims 4
- 101001023037 Homo sapiens Myoferlin Proteins 0.000 claims 4
- 101000873645 Homo sapiens Secretory carrier-associated membrane protein 3 Proteins 0.000 claims 4
- 102100026741 Microsomal glutathione S-transferase 1 Human genes 0.000 claims 4
- 102100035083 Myoferlin Human genes 0.000 claims 4
- 102100035895 Secretory carrier-associated membrane protein 3 Human genes 0.000 claims 4
- 102000046299 Transforming Growth Factor beta1 Human genes 0.000 claims 4
- 101800002279 Transforming growth factor beta-1 Proteins 0.000 claims 4
- 210000005013 brain tissue Anatomy 0.000 claims 4
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 239000003112 inhibitor Substances 0.000 claims 4
- 108010074917 microsomal glutathione S-transferase-I Proteins 0.000 claims 4
- 210000004881 tumor cell Anatomy 0.000 claims 4
- 101150092476 ABCA1 gene Proteins 0.000 claims 3
- 102000055510 ATP Binding Cassette Transporter 1 Human genes 0.000 claims 3
- 108700005241 ATP Binding Cassette Transporter 1 Proteins 0.000 claims 3
- 102100022108 Aspartyl/asparaginyl beta-hydroxylase Human genes 0.000 claims 3
- 102100033040 Carbonic anhydrase 12 Human genes 0.000 claims 3
- 102100035888 Caveolin-1 Human genes 0.000 claims 3
- 101000901030 Homo sapiens Aspartyl/asparaginyl beta-hydroxylase Proteins 0.000 claims 3
- 101000867855 Homo sapiens Carbonic anhydrase 12 Proteins 0.000 claims 3
- 101000715467 Homo sapiens Caveolin-1 Proteins 0.000 claims 3
- 101001098824 Homo sapiens Protein disulfide-isomerase A4 Proteins 0.000 claims 3
- 102100025276 Monocarboxylate transporter 4 Human genes 0.000 claims 3
- 108090000772 Neuropilin-1 Proteins 0.000 claims 3
- 102100029796 Protein S100-A10 Human genes 0.000 claims 3
- 102100037089 Protein disulfide-isomerase A4 Human genes 0.000 claims 3
- 102100023068 Protein kinase C-binding protein NELL1 Human genes 0.000 claims 3
- 108010015695 S100 calcium binding protein A10 Proteins 0.000 claims 3
- 108091006601 SLC16A3 Proteins 0.000 claims 3
- 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 claims 3
- 108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 claims 3
- YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 claims 3
- 239000007787 solid Substances 0.000 claims 3
- 102100026423 Adhesion G protein-coupled receptor E5 Human genes 0.000 claims 2
- 102100035893 CD151 antigen Human genes 0.000 claims 2
- 102100038078 CD276 antigen Human genes 0.000 claims 2
- 102000024905 CD99 Human genes 0.000 claims 2
- 108060001253 CD99 Proteins 0.000 claims 2
- 101000718243 Homo sapiens Adhesion G protein-coupled receptor E5 Proteins 0.000 claims 2
- 101000946874 Homo sapiens CD151 antigen Proteins 0.000 claims 2
- 101000884279 Homo sapiens CD276 antigen Proteins 0.000 claims 2
- 101000727472 Homo sapiens Reticulon-4 Proteins 0.000 claims 2
- 101000680015 Homo sapiens Thioredoxin-related transmembrane protein 1 Proteins 0.000 claims 2
- 102100029831 Reticulon-4 Human genes 0.000 claims 2
- 102100022169 Thioredoxin-related transmembrane protein 1 Human genes 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 238000011156 evaluation Methods 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 claims 1
- 238000004949 mass spectrometry Methods 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462017748P | 2014-06-26 | 2014-06-26 | |
| US62/017,748 | 2014-06-26 | ||
| PCT/US2015/038043 WO2015200823A1 (en) | 2014-06-26 | 2015-06-26 | Markers and therapeutic indicators for glioblastoma multiforme (gbm) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017522555A JP2017522555A (ja) | 2017-08-10 |
| JP2017522555A5 true JP2017522555A5 (enExample) | 2018-08-02 |
Family
ID=54938849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016575349A Pending JP2017522555A (ja) | 2014-06-26 | 2015-06-26 | 多形膠芽腫（ｇｂｍ）のためのマーカー及び治療指標 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20170176439A1 (enExample) |
| EP (1) | EP3161489A4 (enExample) |
| JP (1) | JP2017522555A (enExample) |
| AU (1) | AU2015279660A1 (enExample) |
| CA (1) | CA2953459A1 (enExample) |
| WO (1) | WO2015200823A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018177982A1 (en) | 2017-03-30 | 2018-10-04 | Administración General De La Comunidad Autónoma De Euskadi | Sox1 as a prognostic and predictive biomarker in the treatment of central nervous system tumours |
| CN107653319B (zh) * | 2017-10-27 | 2020-06-30 | 中南大学湘雅医院 | 胶质瘤诊断标志物circ8:61680968|61684188及应用 |
| JP7211604B2 (ja) * | 2017-12-05 | 2023-01-24 | 国立大学法人金沢大学 | 膠芽腫マーカー及びその使用 |
| JP7029745B2 (ja) * | 2017-12-05 | 2022-03-04 | 国立大学法人金沢大学 | 膠芽腫マーカー及びその使用 |
| CN108956997A (zh) * | 2017-12-29 | 2018-12-07 | 广西壮族自治区人民医院 | Cd151蛋白表达量elisa检测方法及试剂盒 |
| CN110211634B (zh) * | 2018-02-05 | 2022-04-05 | 深圳华大基因科技服务有限公司 | 一种多组学数据联合分析的方法 |
| AU2019361781A1 (en) * | 2018-10-14 | 2021-06-03 | Lantern Pharma Inc. | Methods for the treatment of solid tumor cancers using illudins and biomarkers |
| CN114267447B (zh) * | 2021-09-26 | 2025-05-06 | 吴安华 | 一种预测胶质母细胞瘤免疫微环境、预后及治疗敏感性的基因集及系统和方法 |
| PL446389A1 (pl) * | 2023-10-15 | 2025-04-22 | Warszawski Uniwersytet Medyczny | Nowe markery do diagnozowania glejaka wielopostaciowego oraz ich zastosowania |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1708712A1 (en) * | 2003-12-24 | 2006-10-11 | Scios, Inc. | Treatment of malignant gliomas with tgf-beta inhibitors |
| WO2006138275A2 (en) * | 2005-06-13 | 2006-12-28 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| US20090191202A1 (en) * | 2005-09-29 | 2009-07-30 | Jamieson Catriona Helen M | Methods for manipulating phagocytosis mediated by CD47 |
| EP2132336A1 (en) * | 2007-03-02 | 2009-12-16 | Board of Regents, The University of Texas System | Multigene assay to predict outcome in an individual with glioblastoma |
| EP2377952A1 (en) * | 2007-04-26 | 2011-10-19 | Ludwig Institute For Cancer Research | Methods for diagnosing and treating astrocytomas |
| WO2011022335A1 (en) * | 2009-08-21 | 2011-02-24 | Mount Sinai School Of Medicine Of New York University | Methods of using cd44 fusion proteins to treat cancer |
| US8404437B2 (en) * | 2011-03-29 | 2013-03-26 | Taipei Veterans General Hospital | MicroRNA as a cancer progression predictor and its use for treating cancer |
-
2015
- 2015-06-26 EP EP15812565.8A patent/EP3161489A4/en not_active Withdrawn
- 2015-06-26 JP JP2016575349A patent/JP2017522555A/ja active Pending
- 2015-06-26 CA CA2953459A patent/CA2953459A1/en not_active Abandoned
- 2015-06-26 AU AU2015279660A patent/AU2015279660A1/en not_active Abandoned
- 2015-06-26 WO PCT/US2015/038043 patent/WO2015200823A1/en not_active Ceased
-
2016
- 2016-12-23 US US15/390,276 patent/US20170176439A1/en not_active Abandoned
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