JP2017517517A5 - - Google Patents
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- Publication number
- JP2017517517A5 JP2017517517A5 JP2016569655A JP2016569655A JP2017517517A5 JP 2017517517 A5 JP2017517517 A5 JP 2017517517A5 JP 2016569655 A JP2016569655 A JP 2016569655A JP 2016569655 A JP2016569655 A JP 2016569655A JP 2017517517 A5 JP2017517517 A5 JP 2017517517A5
- Authority
- JP
- Japan
- Prior art keywords
- concentration
- formulation
- chloride salt
- peptide
- nr2b9c
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019210223A JP6961661B2 (ja) | 2014-05-28 | 2019-11-21 | Ｔａｔ−ＮＲ２Ｂ９ｃの塩化物塩 |
| JP2021167771A JP7338890B2 (ja) | 2014-05-28 | 2021-10-13 | Ｔａｔ－ＮＲ２Ｂ９ｃの塩化物塩 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462004142P | 2014-05-28 | 2014-05-28 | |
| US62/004,142 | 2014-05-28 | ||
| PCT/IB2015/053995 WO2015181756A1 (en) | 2014-05-28 | 2015-05-28 | Chloride salt of tat-nr2b9c |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019210223A Division JP6961661B2 (ja) | 2014-05-28 | 2019-11-21 | Ｔａｔ−ＮＲ２Ｂ９ｃの塩化物塩 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017517517A JP2017517517A (ja) | 2017-06-29 |
| JP2017517517A5 true JP2017517517A5 (cg-RX-API-DMAC7.html) | 2019-07-25 |
| JP6622222B2 JP6622222B2 (ja) | 2019-12-18 |
Family
ID=54698210
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016569655A Expired - Fee Related JP6622222B2 (ja) | 2014-05-28 | 2015-05-28 | Ｔａｔ−ＮＲ２Ｂ９ｃの塩化物塩 |
| JP2019210223A Expired - Fee Related JP6961661B2 (ja) | 2014-05-28 | 2019-11-21 | Ｔａｔ−ＮＲ２Ｂ９ｃの塩化物塩 |
| JP2021167771A Active JP7338890B2 (ja) | 2014-05-28 | 2021-10-13 | Ｔａｔ－ＮＲ２Ｂ９ｃの塩化物塩 |
| JP2023088154A Pending JP2023113751A (ja) | 2014-05-28 | 2023-05-29 | Ｔａｔ－ＮＲ２Ｂ９ｃの塩化物塩 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019210223A Expired - Fee Related JP6961661B2 (ja) | 2014-05-28 | 2019-11-21 | Ｔａｔ−ＮＲ２Ｂ９ｃの塩化物塩 |
| JP2021167771A Active JP7338890B2 (ja) | 2014-05-28 | 2021-10-13 | Ｔａｔ－ＮＲ２Ｂ９ｃの塩化物塩 |
| JP2023088154A Pending JP2023113751A (ja) | 2014-05-28 | 2023-05-29 | Ｔａｔ－ＮＲ２Ｂ９ｃの塩化物塩 |
Country Status (27)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2172211E (pt) * | 2008-10-01 | 2015-03-09 | Immatics Biotechnologies Gmbh | Composição de peptídeos associados a tumores e vacina anti -cancro relacionada para o tratamento de glioblastoma (gbm) e outros tipos de câncer |
| US10251935B2 (en) * | 2012-11-28 | 2019-04-09 | Nono Inc. | Lyophilized formulation comprising tat-NR2B9C, histidine and trehalose |
| GB201319446D0 (en) | 2013-11-04 | 2013-12-18 | Immatics Biotechnologies Gmbh | Personalized immunotherapy against several neuronal and brain tumors |
| JP6707469B2 (ja) | 2014-05-28 | 2020-06-10 | ノノ インコーポレイテッド | アセチル化スカベンジャーを含むＴａｔ−ＮＲ２Ｂ９ｃの凍結乾燥製剤 |
| LT3149048T (lt) | 2014-05-28 | 2020-05-11 | Nono Inc. | Tat-nr2b9c chlorido druska |
| GB201511546D0 (en) | 2015-07-01 | 2015-08-12 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
| IL308735A (en) | 2015-07-01 | 2024-01-01 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
| GB201620611D0 (en) * | 2016-12-05 | 2017-01-18 | Univ Of Lancaster | Treatment of neurological diseases |
| BR112020000115A2 (pt) * | 2017-07-05 | 2020-07-07 | Biocells (Beijing) Biotech Co., Ltd. | sais farmaceuticamente aceitáveis de polipeptídeos e uso dos mesmos |
| CN110627877A (zh) * | 2019-09-25 | 2019-12-31 | 成都奥达生物科技有限公司 | 一种psd-95抑制剂 |
| US20230055441A1 (en) * | 2020-01-09 | 2023-02-23 | Nono Inc. | Plasmin-resistant peptides for treating stroke and related conditions |
| CN111560050A (zh) * | 2020-05-25 | 2020-08-21 | 成都圣诺生物制药有限公司 | 一种Nerinetide的制备方法 |
| BR112023013640A2 (pt) | 2021-01-08 | 2023-12-05 | Nono Inc | Peptídeos resistentes à plasmina para índice terapêutico melhorado |
| CN113735938B (zh) * | 2021-07-30 | 2024-11-08 | 英纳氏(珠海)药业有限公司 | 一种神经保护多肽化合物及其应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6685940B2 (en) * | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
| PT2275119E (pt) * | 1995-07-27 | 2013-11-21 | Genentech Inc | Formulação de proteína liofilizada isotónica estável |
| US7510824B2 (en) | 1999-06-02 | 2009-03-31 | Nono Inc. | Method of screening peptides useful in treating traumatic injury to the brain or spinal cord |
| WO2007016366A2 (en) * | 2005-07-29 | 2007-02-08 | Yale University | Defined culture conditions of human embryonic stem cells |
| JO3324B1 (ar) | 2006-04-21 | 2019-03-13 | Amgen Inc | مركبات علاجية مجففة بالتبريد تتعلق بالعصارة الهضمية |
| EP1884521A1 (en) | 2006-07-31 | 2008-02-06 | Xigen S.A. | Fusion peptide for inhibiting interaction of neuronal NMDA receptor (NMDAR) and NMDAR interacting proteins |
| EP2120987B1 (en) | 2007-03-02 | 2014-01-15 | NoNO Inc. | Treating stroke and other diseases without inhibiting n-type calcium channels |
| MX2009012964A (es) * | 2007-06-01 | 2010-01-14 | Acologix Inc | Formulacion de peptido estable a alta temperatura. |
| US8008253B2 (en) * | 2007-07-03 | 2011-08-30 | Andrew Tasker | Treatment for anxiety |
| DK2320927T3 (en) * | 2008-07-09 | 2015-09-14 | Univ Copenhagen | Modified peptides as potent inhibitors of the PSD-95 / NMDA receptor interaction |
| EP3808366A1 (en) * | 2009-06-10 | 2021-04-21 | NoNO Inc. | Treatment regimes for treatment of neurological disease |
| CA2807946C (en) * | 2010-08-12 | 2018-09-25 | Nono Inc. | Treatment of penetrative injury to the brain |
| EP2621945B1 (en) * | 2010-09-28 | 2018-04-11 | NoNO Inc. | Nd2 peptides and methods of treating neurological disease |
| ES2544573T3 (es) * | 2011-05-13 | 2015-09-01 | Københavns Universitet (University Of Copenhagen) | Inhibidores diméricos de afinidad elevada de PSD-95 y su uso para el tratamiento del daño cerebral isquémico y del dolor |
| CN102241745A (zh) * | 2011-05-19 | 2011-11-16 | 南京医科大学 | 多肽类似物Tat-HA-NR2B9C及其制备方法和应用 |
| HUE058238T2 (hu) * | 2011-06-24 | 2022-07-28 | Nono Inc | Ischaemia kombinációs terápiája |
| US9241970B2 (en) * | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
| JP6279483B2 (ja) | 2011-12-13 | 2018-02-14 | ノノ インコーポレイテッド | くも膜下出血および虚血の治療法 |
| GB201220474D0 (en) * | 2012-11-14 | 2012-12-26 | Sagetis Biotech Sl | Polypeptides |
| HUE043820T2 (hu) | 2012-11-28 | 2019-09-30 | Nono Inc | Liofilizált TAT-NR2B9c készítmény |
| US10251935B2 (en) | 2012-11-28 | 2019-04-09 | Nono Inc. | Lyophilized formulation comprising tat-NR2B9C, histidine and trehalose |
| JP6707469B2 (ja) * | 2014-05-28 | 2020-06-10 | ノノ インコーポレイテッド | アセチル化スカベンジャーを含むＴａｔ−ＮＲ２Ｂ９ｃの凍結乾燥製剤 |
| LT3149048T (lt) * | 2014-05-28 | 2020-05-11 | Nono Inc. | Tat-nr2b9c chlorido druska |
-
2015
- 2015-05-28 LT LTEP15799583.8T patent/LT3149048T/lt unknown
- 2015-05-28 MX MX2016015457A patent/MX374958B/es active IP Right Grant
- 2015-05-28 US US15/313,940 patent/US10206973B2/en active Active
- 2015-05-28 PL PL15799583T patent/PL3149048T3/pl unknown
- 2015-05-28 SM SM20200307T patent/SMT202000307T1/it unknown
- 2015-05-28 RU RU2016150678A patent/RU2707885C2/ru active
- 2015-05-28 AU AU2015265487A patent/AU2015265487B2/en not_active Ceased
- 2015-05-28 CN CN201580028269.3A patent/CN106661126B/zh not_active Expired - Fee Related
- 2015-05-28 ES ES15799583T patent/ES2784500T3/es active Active
- 2015-05-28 KR KR1020227019189A patent/KR102605540B1/ko active Active
- 2015-05-28 ME MEP-2020-120A patent/ME03790B/me unknown
- 2015-05-28 JP JP2016569655A patent/JP6622222B2/ja not_active Expired - Fee Related
- 2015-05-28 PT PT157995838T patent/PT3149048T/pt unknown
- 2015-05-28 HR HRP20200462TT patent/HRP20200462T1/hr unknown
- 2015-05-28 SI SI201531132T patent/SI3149048T1/sl unknown
- 2015-05-28 BR BR112016027814A patent/BR112016027814A2/pt active Search and Examination
- 2015-05-28 HU HUE15799583A patent/HUE049074T2/hu unknown
- 2015-05-28 SG SG10202001285XA patent/SG10202001285XA/en unknown
- 2015-05-28 DK DK15799583.8T patent/DK3149048T3/da active
- 2015-05-28 SG SG11201609911YA patent/SG11201609911YA/en unknown
- 2015-05-28 ES ES20152821T patent/ES2974228T3/es active Active
- 2015-05-28 CA CA2950395A patent/CA2950395C/en active Active
- 2015-05-28 EP EP15799583.8A patent/EP3149048B1/en active Active
- 2015-05-28 CN CN202111366962.5A patent/CN114057895A/zh active Pending
- 2015-05-28 UA UAA201613470A patent/UA123820C2/uk unknown
- 2015-05-28 KR KR1020217031792A patent/KR102407856B1/ko active Active
- 2015-05-28 EP EP20152821.3A patent/EP3757134B1/en active Active
- 2015-05-28 WO PCT/IB2015/053995 patent/WO2015181756A1/en not_active Ceased
- 2015-05-28 RS RS20200367A patent/RS60625B1/sr unknown
- 2015-05-28 RU RU2019138024A patent/RU2019138024A/ru unknown
- 2015-05-28 KR KR1020167036752A patent/KR102311038B1/ko not_active Expired - Fee Related
-
2016
- 2016-11-24 MX MX2020009633A patent/MX2020009633A/es unknown
- 2016-11-28 IL IL249252A patent/IL249252B/en active IP Right Grant
- 2016-12-21 ZA ZA2016/08843A patent/ZA201608843B/en unknown
-
2018
- 2018-09-11 US US16/128,423 patent/US10758589B2/en active Active
-
2019
- 2019-11-21 JP JP2019210223A patent/JP6961661B2/ja not_active Expired - Fee Related
-
2020
- 2020-03-18 CY CY20201100251T patent/CY1122793T1/el unknown
- 2020-06-17 US US16/904,230 patent/US11266714B2/en active Active
- 2020-11-13 AU AU2020267304A patent/AU2020267304C1/en not_active Ceased
-
2021
- 2021-10-13 JP JP2021167771A patent/JP7338890B2/ja active Active
- 2021-12-08 US US17/545,995 patent/US11911438B2/en active Active
-
2023
- 2023-05-29 JP JP2023088154A patent/JP2023113751A/ja active Pending
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