JP2017515495A5 - - Google Patents
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- Publication number
- JP2017515495A5 JP2017515495A5 JP2016568696A JP2016568696A JP2017515495A5 JP 2017515495 A5 JP2017515495 A5 JP 2017515495A5 JP 2016568696 A JP2016568696 A JP 2016568696A JP 2016568696 A JP2016568696 A JP 2016568696A JP 2017515495 A5 JP2017515495 A5 JP 2017515495A5
- Authority
- JP
- Japan
- Prior art keywords
- butanediol
- concentration
- clostridium
- vitamin
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims description 40
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 24
- 235000015097 nutrients Nutrition 0.000 claims description 22
- 241000193403 Clostridium Species 0.000 claims description 18
- OWBTYPJTUOEWEK-UHFFFAOYSA-N butane-2,3-diol Chemical compound CC(O)C(C)O OWBTYPJTUOEWEK-UHFFFAOYSA-N 0.000 claims description 18
- 239000007788 liquid Substances 0.000 claims description 18
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 15
- 244000005700 microbiome Species 0.000 claims description 15
- 239000002028 Biomass Substances 0.000 claims description 13
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims description 12
- 229930003571 Vitamin B5 Natural products 0.000 claims description 12
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 claims description 12
- 229960002079 calcium pantothenate Drugs 0.000 claims description 12
- 238000004519 manufacturing process Methods 0.000 claims description 12
- 239000011675 vitamin B5 Substances 0.000 claims description 12
- 235000009492 vitamin B5 Nutrition 0.000 claims description 12
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 7
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 7
- 229930003756 Vitamin B7 Natural products 0.000 claims description 7
- 235000011912 vitamin B7 Nutrition 0.000 claims description 7
- 239000011735 vitamin B7 Substances 0.000 claims description 7
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 claims description 6
- BTANRVKWQNVYAZ-UHFFFAOYSA-N butan-2-ol Chemical compound CCC(C)O BTANRVKWQNVYAZ-UHFFFAOYSA-N 0.000 claims description 6
- 241001656809 Clostridium autoethanogenum Species 0.000 claims description 5
- 238000000855 fermentation Methods 0.000 claims description 5
- 230000004151 fermentation Effects 0.000 claims description 5
- 230000000813 microbial effect Effects 0.000 claims description 5
- 239000000758 substrate Substances 0.000 claims description 5
- ROWKJAVDOGWPAT-UHFFFAOYSA-N Acetoin Chemical compound CC(O)C(C)=O ROWKJAVDOGWPAT-UHFFFAOYSA-N 0.000 claims description 4
- 230000000789 acetogenic effect Effects 0.000 claims description 3
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 claims description 2
- GFAZHVHNLUBROE-UHFFFAOYSA-N hydroxymethyl propionaldehyde Natural products CCC(=O)CO GFAZHVHNLUBROE-UHFFFAOYSA-N 0.000 claims description 2
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical compound CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims description 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 claims description 2
- UORVGPXVDQYIDP-UHFFFAOYSA-N borane Chemical compound B UORVGPXVDQYIDP-UHFFFAOYSA-N 0.000 claims 2
- 230000001228 trophic effect Effects 0.000 claims 2
- 241000186216 Corynebacterium Species 0.000 claims 1
- WDJHALXBUFZDSR-UHFFFAOYSA-M acetoacetate Chemical compound CC(=O)CC([O-])=O WDJHALXBUFZDSR-UHFFFAOYSA-M 0.000 claims 1
- 229910000085 borane Inorganic materials 0.000 claims 1
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 1
- 229930003451 Vitamin B1 Natural products 0.000 description 6
- 230000001413 cellular effect Effects 0.000 description 6
- 229960003495 thiamine Drugs 0.000 description 6
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 6
- 235000010374 vitamin B1 Nutrition 0.000 description 6
- 239000011691 vitamin B1 Substances 0.000 description 6
- 241001468161 Acetobacterium Species 0.000 description 4
- 241000178986 Oxobacter Species 0.000 description 4
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 description 4
- ZSLZBFCDCINBPY-ZSJPKINUSA-N acetyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 ZSLZBFCDCINBPY-ZSJPKINUSA-N 0.000 description 4
- 241000880298 Baculum Species 0.000 description 2
- 241001464894 Blautia producta Species 0.000 description 2
- KAKZBPTYRLMSJV-UHFFFAOYSA-N Butadiene Chemical compound C=CC=C KAKZBPTYRLMSJV-UHFFFAOYSA-N 0.000 description 2
- 241001656810 Clostridium aceticum Species 0.000 description 2
- 241001468167 Clostridium magnum Species 0.000 description 2
- 241000186394 Eubacterium Species 0.000 description 2
- 241000186398 Eubacterium limosum Species 0.000 description 2
- 241001251094 Formica Species 0.000 description 2
- 241001409459 Morella Species 0.000 description 2
- 241000191992 Peptostreptococcus Species 0.000 description 2
- 241000204388 Sporomusa Species 0.000 description 2
- 241001441724 Tetraodontidae Species 0.000 description 2
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- XFTRTWQBIOMVPK-UHFFFAOYSA-L citramalate(2-) Chemical compound [O-]C(=O)C(O)(C)CC([O-])=O XFTRTWQBIOMVPK-UHFFFAOYSA-L 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 239000004626 polylactic acid Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/283,287 | 2014-05-21 | ||
| US14/283,287 US9701987B2 (en) | 2014-05-21 | 2014-05-21 | Fermentation process for the production and control of pyruvate-derived products |
| PCT/US2015/031857 WO2015179578A1 (en) | 2014-05-21 | 2015-05-20 | Fermentation process for the production and control of pyruvate-derived products |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017515495A JP2017515495A (ja) | 2017-06-15 |
| JP2017515495A5 true JP2017515495A5 (https=) | 2018-06-28 |
| JP6595508B2 JP6595508B2 (ja) | 2019-10-23 |
Family
ID=54554733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016568696A Active JP6595508B2 (ja) | 2014-05-21 | 2015-05-20 | ピルビン酸塩由来生成物の生成及び制御のための発酵プロセス |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9701987B2 (https=) |
| EP (1) | EP3146058B1 (https=) |
| JP (1) | JP6595508B2 (https=) |
| KR (1) | KR102524251B1 (https=) |
| CN (1) | CN106507678B (https=) |
| BR (1) | BR112016027080B8 (https=) |
| CA (1) | CA2948909C (https=) |
| ES (1) | ES2818094T3 (https=) |
| PT (1) | PT3146058T (https=) |
| TW (1) | TWI657143B (https=) |
| WO (1) | WO2015179578A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10053711B2 (en) | 2013-08-02 | 2018-08-21 | The Board Of Regents For Oklahoma State University | Method improving producer gas fermentation |
| US12252654B2 (en) * | 2020-10-21 | 2025-03-18 | ExxonMobil Technology and Engineering Company | Integrated biomass gasification and electrolysis |
| KR102443037B1 (ko) * | 2020-10-23 | 2022-09-14 | 한국과학기술연구원 | 에탄올을 포함하는 합성 가스로부터 2,3-부탄디올 제조용 배지 조성물 및 이를 이용한 2,3-부탄디올 생산 방법 |
| WO2022125362A1 (en) * | 2020-12-08 | 2022-06-16 | Jupeng Bio (Hk) Limited | Process and composition for controlling ethanol production |
| CN113755534B (zh) * | 2021-08-13 | 2024-02-27 | 巨鹏生物(香港)有限公司 | 通过焦炉煤气发酵制备乙醇的方法和系统 |
| WO2023077101A1 (en) | 2021-10-29 | 2023-05-04 | Synata Bio, Inc. | Method of dewatering |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5173429A (en) | 1990-11-09 | 1992-12-22 | The Board Of Trustees Of The University Of Arkansas | Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism |
| US5821111A (en) | 1994-03-31 | 1998-10-13 | Bioengineering Resources, Inc. | Bioconversion of waste biomass to useful products |
| US5807722A (en) | 1992-10-30 | 1998-09-15 | Bioengineering Resources, Inc. | Biological production of acetic acid from waste gases with Clostridium ljungdahlii |
| US6136577A (en) | 1992-10-30 | 2000-10-24 | Bioengineering Resources, Inc. | Biological production of ethanol from waste gases with Clostridium ljungdahlii |
| US5593886A (en) | 1992-10-30 | 1997-01-14 | Gaddy; James L. | Clostridium stain which produces acetic acid from waste gases |
| KR100387301B1 (ko) | 1996-07-01 | 2003-06-12 | 바이오 엔지니어링 리소스 인코포레이티드 | 폐가스로부터의 생성물의 생물학적 제조방법 |
| UA72220C2 (uk) | 1998-09-08 | 2005-02-15 | Байоенджініерінг Рісорсиз, Інк. | Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання |
| WO2002008438A2 (en) * | 2000-07-25 | 2002-01-31 | Bioengineering Resources, Inc. | Methods for increasing the production of ethanol from microbial fermentation |
| NZ560757A (en) | 2007-10-28 | 2010-07-30 | Lanzatech New Zealand Ltd | Improved carbon capture in microbial fermentation of industrial gases to ethanol |
| JP5600296B2 (ja) * | 2007-11-13 | 2014-10-01 | ランザテク・ニュージーランド・リミテッド | 新規細菌及びその使用法 |
| BRPI0909841B1 (pt) * | 2008-03-10 | 2019-02-05 | Ineos Bio Sa | métodos de sustentação e de prevenção de perda rápida de cultura de microorganismos em reator de fermentação de singás em concentração diminuída ou ausência de vários substratos |
| CN102317463B (zh) * | 2008-06-09 | 2014-12-03 | 蓝瑟科技纽西兰有限公司 | 厌氧微生物发酵生产丁二醇 |
| US8143037B2 (en) | 2010-03-19 | 2012-03-27 | Coskata, Inc. | Ethanologenic Clostridium species, Clostridium coskatii |
| AU2011249140B2 (en) | 2010-05-04 | 2013-10-03 | Lanzatech Nz, Inc. | Improved fermentation of waste gases |
| US9012190B2 (en) | 2011-06-15 | 2015-04-21 | Butamax Advanced Biofuels Llc | Use of thiamine and nicotine adenine dinucleotide for butanol production |
| US20120045807A1 (en) * | 2010-08-19 | 2012-02-23 | Lanzatech New Zealand Limited | Process for producing chemicals using microbial fermentation of substrates comprising carbon monoxide |
| AU2011316891B2 (en) | 2010-10-22 | 2013-09-19 | Lanzatech Nz, Inc. | Methods and systems for the production of hydrocarbon products |
| EA024474B1 (ru) | 2010-10-29 | 2016-09-30 | Ланцатек Нью Зилэнд Лимитед | Способ производства углеводородных продуктов |
| CN103582703A (zh) * | 2011-03-31 | 2014-02-12 | 新西兰郎泽科技公司 | 一种用于控制丁二醇生产的发酵方法 |
| US8735115B2 (en) * | 2012-03-30 | 2014-05-27 | Lanzatech New Zealand Limited | Method for controlling the sulphur concentration in a fermentation method |
| US20130316364A1 (en) * | 2012-05-23 | 2013-11-28 | Lanzatech New Zealand Limited | Selection Method and Recombinant Microorganisms and uses Therefor |
-
2014
- 2014-05-21 US US14/283,287 patent/US9701987B2/en active Active
-
2015
- 2015-05-20 JP JP2016568696A patent/JP6595508B2/ja active Active
- 2015-05-20 EP EP15796360.4A patent/EP3146058B1/en active Active
- 2015-05-20 BR BR112016027080A patent/BR112016027080B8/pt active IP Right Grant
- 2015-05-20 KR KR1020167035124A patent/KR102524251B1/ko active Active
- 2015-05-20 PT PT157963604T patent/PT3146058T/pt unknown
- 2015-05-20 CN CN201580032498.2A patent/CN106507678B/zh active Active
- 2015-05-20 ES ES15796360T patent/ES2818094T3/es active Active
- 2015-05-20 CA CA2948909A patent/CA2948909C/en active Active
- 2015-05-20 WO PCT/US2015/031857 patent/WO2015179578A1/en not_active Ceased
- 2015-05-21 TW TW104116326A patent/TWI657143B/zh active
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