JP2017515495A5 - - Google Patents
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- Publication number
- JP2017515495A5 JP2017515495A5 JP2016568696A JP2016568696A JP2017515495A5 JP 2017515495 A5 JP2017515495 A5 JP 2017515495A5 JP 2016568696 A JP2016568696 A JP 2016568696A JP 2016568696 A JP2016568696 A JP 2016568696A JP 2017515495 A5 JP2017515495 A5 JP 2017515495A5
- Authority
- JP
- Japan
- Prior art keywords
- butanediol
- concentration
- clostridium
- vitamin
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims description 40
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 24
- 235000015097 nutrients Nutrition 0.000 claims description 22
- 241000193403 Clostridium Species 0.000 claims description 18
- OWBTYPJTUOEWEK-UHFFFAOYSA-N butane-2,3-diol Chemical compound CC(O)C(C)O OWBTYPJTUOEWEK-UHFFFAOYSA-N 0.000 claims description 18
- 239000007788 liquid Substances 0.000 claims description 18
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 15
- 244000005700 microbiome Species 0.000 claims description 15
- 239000002028 Biomass Substances 0.000 claims description 13
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims description 12
- 229930003571 Vitamin B5 Natural products 0.000 claims description 12
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 claims description 12
- 229960002079 calcium pantothenate Drugs 0.000 claims description 12
- 238000004519 manufacturing process Methods 0.000 claims description 12
- 239000011675 vitamin B5 Substances 0.000 claims description 12
- 235000009492 vitamin B5 Nutrition 0.000 claims description 12
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 7
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 7
- 229930003756 Vitamin B7 Natural products 0.000 claims description 7
- 235000011912 vitamin B7 Nutrition 0.000 claims description 7
- 239000011735 vitamin B7 Substances 0.000 claims description 7
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 claims description 6
- BTANRVKWQNVYAZ-UHFFFAOYSA-N butan-2-ol Chemical compound CCC(C)O BTANRVKWQNVYAZ-UHFFFAOYSA-N 0.000 claims description 6
- 241001656809 Clostridium autoethanogenum Species 0.000 claims description 5
- 238000000855 fermentation Methods 0.000 claims description 5
- 230000004151 fermentation Effects 0.000 claims description 5
- 230000000813 microbial effect Effects 0.000 claims description 5
- 239000000758 substrate Substances 0.000 claims description 5
- ROWKJAVDOGWPAT-UHFFFAOYSA-N Acetoin Chemical compound CC(O)C(C)=O ROWKJAVDOGWPAT-UHFFFAOYSA-N 0.000 claims description 4
- 230000000789 acetogenic effect Effects 0.000 claims description 3
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 claims description 2
- GFAZHVHNLUBROE-UHFFFAOYSA-N hydroxymethyl propionaldehyde Natural products CCC(=O)CO GFAZHVHNLUBROE-UHFFFAOYSA-N 0.000 claims description 2
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical compound CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims description 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 claims description 2
- UORVGPXVDQYIDP-UHFFFAOYSA-N borane Chemical compound B UORVGPXVDQYIDP-UHFFFAOYSA-N 0.000 claims 2
- 230000001228 trophic effect Effects 0.000 claims 2
- 241000186216 Corynebacterium Species 0.000 claims 1
- WDJHALXBUFZDSR-UHFFFAOYSA-M acetoacetate Chemical compound CC(=O)CC([O-])=O WDJHALXBUFZDSR-UHFFFAOYSA-M 0.000 claims 1
- 229910000085 borane Inorganic materials 0.000 claims 1
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 1
- 229930003451 Vitamin B1 Natural products 0.000 description 6
- 230000001413 cellular effect Effects 0.000 description 6
- 229960003495 thiamine Drugs 0.000 description 6
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 6
- 235000010374 vitamin B1 Nutrition 0.000 description 6
- 239000011691 vitamin B1 Substances 0.000 description 6
- 241001468161 Acetobacterium Species 0.000 description 4
- 241000178986 Oxobacter Species 0.000 description 4
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 description 4
- ZSLZBFCDCINBPY-ZSJPKINUSA-N acetyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 ZSLZBFCDCINBPY-ZSJPKINUSA-N 0.000 description 4
- 241000880298 Baculum Species 0.000 description 2
- 241001464894 Blautia producta Species 0.000 description 2
- KAKZBPTYRLMSJV-UHFFFAOYSA-N Butadiene Chemical compound C=CC=C KAKZBPTYRLMSJV-UHFFFAOYSA-N 0.000 description 2
- 241001656810 Clostridium aceticum Species 0.000 description 2
- 241001468167 Clostridium magnum Species 0.000 description 2
- 241000186394 Eubacterium Species 0.000 description 2
- 241000186398 Eubacterium limosum Species 0.000 description 2
- 241001251094 Formica Species 0.000 description 2
- 241001409459 Morella Species 0.000 description 2
- 241000191992 Peptostreptococcus Species 0.000 description 2
- 241000204388 Sporomusa Species 0.000 description 2
- 241001441724 Tetraodontidae Species 0.000 description 2
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- XFTRTWQBIOMVPK-UHFFFAOYSA-L citramalate(2-) Chemical compound [O-]C(=O)C(O)(C)CC([O-])=O XFTRTWQBIOMVPK-UHFFFAOYSA-L 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 239000004626 polylactic acid Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/283,287 US9701987B2 (en) | 2014-05-21 | 2014-05-21 | Fermentation process for the production and control of pyruvate-derived products |
| US14/283,287 | 2014-05-21 | ||
| PCT/US2015/031857 WO2015179578A1 (en) | 2014-05-21 | 2015-05-20 | Fermentation process for the production and control of pyruvate-derived products |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017515495A JP2017515495A (ja) | 2017-06-15 |
| JP2017515495A5 true JP2017515495A5 (https=) | 2018-06-28 |
| JP6595508B2 JP6595508B2 (ja) | 2019-10-23 |
Family
ID=54554733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016568696A Active JP6595508B2 (ja) | 2014-05-21 | 2015-05-20 | ピルビン酸塩由来生成物の生成及び制御のための発酵プロセス |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9701987B2 (https=) |
| EP (1) | EP3146058B1 (https=) |
| JP (1) | JP6595508B2 (https=) |
| KR (1) | KR102524251B1 (https=) |
| CN (1) | CN106507678B (https=) |
| BR (1) | BR112016027080B8 (https=) |
| CA (1) | CA2948909C (https=) |
| ES (1) | ES2818094T3 (https=) |
| PT (1) | PT3146058T (https=) |
| TW (1) | TWI657143B (https=) |
| WO (1) | WO2015179578A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10053711B2 (en) | 2013-08-02 | 2018-08-21 | The Board Of Regents For Oklahoma State University | Method improving producer gas fermentation |
| US12252654B2 (en) * | 2020-10-21 | 2025-03-18 | ExxonMobil Technology and Engineering Company | Integrated biomass gasification and electrolysis |
| KR102443037B1 (ko) * | 2020-10-23 | 2022-09-14 | 한국과학기술연구원 | 에탄올을 포함하는 합성 가스로부터 2,3-부탄디올 제조용 배지 조성물 및 이를 이용한 2,3-부탄디올 생산 방법 |
| WO2022125362A1 (en) | 2020-12-08 | 2022-06-16 | Jupeng Bio (Hk) Limited | Process and composition for controlling ethanol production |
| CN113755534B (zh) * | 2021-08-13 | 2024-02-27 | 巨鹏生物(香港)有限公司 | 通过焦炉煤气发酵制备乙醇的方法和系统 |
| US12466752B2 (en) | 2021-10-29 | 2025-11-11 | Synata Bio, Inc. | Method of dewatering |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5173429A (en) | 1990-11-09 | 1992-12-22 | The Board Of Trustees Of The University Of Arkansas | Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism |
| US6136577A (en) | 1992-10-30 | 2000-10-24 | Bioengineering Resources, Inc. | Biological production of ethanol from waste gases with Clostridium ljungdahlii |
| US5593886A (en) | 1992-10-30 | 1997-01-14 | Gaddy; James L. | Clostridium stain which produces acetic acid from waste gases |
| US5821111A (en) | 1994-03-31 | 1998-10-13 | Bioengineering Resources, Inc. | Bioconversion of waste biomass to useful products |
| US5807722A (en) | 1992-10-30 | 1998-09-15 | Bioengineering Resources, Inc. | Biological production of acetic acid from waste gases with Clostridium ljungdahlii |
| KR100387301B1 (ko) | 1996-07-01 | 2003-06-12 | 바이오 엔지니어링 리소스 인코포레이티드 | 폐가스로부터의 생성물의 생물학적 제조방법 |
| UA72220C2 (uk) | 1998-09-08 | 2005-02-15 | Байоенджініерінг Рісорсиз, Інк. | Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання |
| DK1303629T3 (da) * | 2000-07-25 | 2006-10-30 | Emmaus Foundation Inc | Fremgangsmåde til forögelse af ethanolproduktion fra mikrobiel fermetering |
| NZ560757A (en) | 2007-10-28 | 2010-07-30 | Lanzatech New Zealand Ltd | Improved carbon capture in microbial fermentation of industrial gases to ethanol |
| CN102876609A (zh) * | 2007-11-13 | 2013-01-16 | 兰扎泰克新西兰有限公司 | 新型菌及其使用方法 |
| CN102131936B (zh) * | 2008-03-10 | 2016-08-10 | 伊内奥斯美国公司 | 在合成气发酵过程中用于在多种底物浓度降低或不存在下维持微生物培养物的方法 |
| BRPI0915017B1 (pt) * | 2008-06-09 | 2018-12-26 | Lanzatech New Zealand Limited | método para produzir 2,3-butanodiol pela fermentação microbiana de um substrato gasoso compreendendo co |
| US8143037B2 (en) | 2010-03-19 | 2012-03-27 | Coskata, Inc. | Ethanologenic Clostridium species, Clostridium coskatii |
| AU2011249140B2 (en) | 2010-05-04 | 2013-10-03 | Lanzatech Nz, Inc. | Improved fermentation of waste gases |
| US9012190B2 (en) | 2011-06-15 | 2015-04-21 | Butamax Advanced Biofuels Llc | Use of thiamine and nicotine adenine dinucleotide for butanol production |
| US20120045807A1 (en) * | 2010-08-19 | 2012-02-23 | Lanzatech New Zealand Limited | Process for producing chemicals using microbial fermentation of substrates comprising carbon monoxide |
| MY158746A (en) | 2010-10-22 | 2016-11-15 | Lanzatech New Zealand Ltd | Methods and systems for the production of hydrocarbon products |
| EP2633059A4 (en) | 2010-10-29 | 2016-10-19 | Lanzatech New Zealand Ltd | METHOD AND SYSTEMS FOR THE PRODUCTION OF HYDROCARBON PRODUCTS |
| US8673603B2 (en) * | 2011-03-31 | 2014-03-18 | Lanzatech New Zealand Limited | Fermentation process for controlling butanediol production |
| US8735115B2 (en) * | 2012-03-30 | 2014-05-27 | Lanzatech New Zealand Limited | Method for controlling the sulphur concentration in a fermentation method |
| US20130316364A1 (en) * | 2012-05-23 | 2013-11-28 | Lanzatech New Zealand Limited | Selection Method and Recombinant Microorganisms and uses Therefor |
-
2014
- 2014-05-21 US US14/283,287 patent/US9701987B2/en active Active
-
2015
- 2015-05-20 WO PCT/US2015/031857 patent/WO2015179578A1/en not_active Ceased
- 2015-05-20 EP EP15796360.4A patent/EP3146058B1/en active Active
- 2015-05-20 JP JP2016568696A patent/JP6595508B2/ja active Active
- 2015-05-20 KR KR1020167035124A patent/KR102524251B1/ko active Active
- 2015-05-20 CN CN201580032498.2A patent/CN106507678B/zh active Active
- 2015-05-20 BR BR112016027080A patent/BR112016027080B8/pt active IP Right Grant
- 2015-05-20 CA CA2948909A patent/CA2948909C/en active Active
- 2015-05-20 PT PT157963604T patent/PT3146058T/pt unknown
- 2015-05-20 ES ES15796360T patent/ES2818094T3/es active Active
- 2015-05-21 TW TW104116326A patent/TWI657143B/zh active
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