JP2017509672A5 - - Google Patents

Download PDF

Info

Publication number
JP2017509672A5
JP2017509672A5 JP2016560467A JP2016560467A JP2017509672A5 JP 2017509672 A5 JP2017509672 A5 JP 2017509672A5 JP 2016560467 A JP2016560467 A JP 2016560467A JP 2016560467 A JP2016560467 A JP 2016560467A JP 2017509672 A5 JP2017509672 A5 JP 2017509672A5
Authority
JP
Japan
Prior art keywords
cancer
compound
salt
medicament
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016560467A
Other languages
English (en)
Japanese (ja)
Other versions
JP6557253B2 (ja
JP2017509672A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/023954 external-priority patent/WO2015153814A1/en
Publication of JP2017509672A publication Critical patent/JP2017509672A/ja
Publication of JP2017509672A5 publication Critical patent/JP2017509672A5/ja
Application granted granted Critical
Publication of JP6557253B2 publication Critical patent/JP6557253B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016560467A 2014-04-01 2015-04-01 抗腫瘍化合物としてのシグマ−２受容体リガンド薬物結合体、その合成法及び使用 Expired - Fee Related JP6557253B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461973366P 2014-04-01 2014-04-01
US61/973,366 2014-04-01
PCT/US2015/023954 WO2015153814A1 (en) 2014-04-01 2015-04-01 Sigma-2 receptor ligand drug conjugates as antitumor compounds, methods of synthesis and uses thereof

Publications (3)

Publication Number Publication Date
JP2017509672A JP2017509672A (ja) 2017-04-06
JP2017509672A5 true JP2017509672A5 (https=) 2018-01-25
JP6557253B2 JP6557253B2 (ja) 2019-08-07

Family

ID=54241267

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016560467A Expired - Fee Related JP6557253B2 (ja) 2014-04-01 2015-04-01 抗腫瘍化合物としてのシグマ−２受容体リガンド薬物結合体、その合成法及び使用

Country Status (8)

Country Link
US (5) US10087175B2 (https=)
EP (1) EP3126356B1 (https=)
JP (1) JP6557253B2 (https=)
CN (1) CN106459011B (https=)
AU (2) AU2015240775B2 (https=)
CA (1) CA2944069C (https=)
ES (1) ES2743701T3 (https=)
WO (1) WO2015153814A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015153814A1 (en) 2014-04-01 2015-10-08 Washington University Sigma-2 receptor ligand drug conjugates as antitumor compounds, methods of synthesis and uses thereof
US11175296B2 (en) 2016-10-26 2021-11-16 Washington University Methods of diagnosing and treating cancer comprising ME1
WO2018218087A1 (en) * 2017-05-24 2018-11-29 K-Gen, Inc. Methods of cancer treatment
US11541116B1 (en) 2022-01-07 2023-01-03 Kojin Therapeutics, Inc. Methods and compositions for inducing ferroptosis in vivo

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7358262B2 (en) * 2003-01-29 2008-04-15 Whitehead Institute For Biomedical Research Identification of genotype-selective anti-tumor agents
NZ560320A (en) * 2005-01-25 2011-02-25 Prolexys Pharmaceuticals Inc Quinoxaline derivatives as antitumor agents
JP2008537726A (ja) * 2005-01-25 2008-09-25 ホワイトヘッド インスティチュート フォー バイオメディカル リサーチ 癌細胞を殺傷するためのエラスチンアナログおよびその使用
US20070161644A1 (en) * 2005-01-25 2007-07-12 Stockwell Brent R Erastin analogs and uses thereof
WO2006130426A2 (en) * 2005-05-27 2006-12-07 Kemia, Inc. Modulators of ccr-5 activity
BRPI0620264A2 (pt) 2005-12-22 2011-11-08 Prolexys Pharmaceuticals Inc quinazolonas aril-substituìdas e sua utilização
WO2008013987A2 (en) * 2006-07-27 2008-01-31 Prolexys Pharmaceuticals, Inc. N-alkyl substituted piperazinylmethylquinazolinones and azepanylmethylquinazolinones
EP2061759B1 (en) * 2006-10-04 2013-03-27 Bristol-Myers Squibb Company Cyclic modulators of chemokine receptor activity
US8143222B2 (en) 2007-10-22 2012-03-27 Washington University Modular platform for targeted therapeutic delivery
WO2015153814A1 (en) * 2014-04-01 2015-10-08 Washington University Sigma-2 receptor ligand drug conjugates as antitumor compounds, methods of synthesis and uses thereof

Similar Documents

Publication Publication Date Title
HRP20210848T1 (hr) Sastavi i postupci za sprječavanje aktivnosti arginaze
JP2010533206A5 (https=)
ES2378692T3 (es) Las 1H-benzimidazol-4-carboxamidas sustituidas con fenilo en la posición 2 son potentes inhibidores de PARP
JP5685231B2 (ja) ジアザベンゾ［デ］アントラセン−３−オン化合物、及び、ｐａｒｐの阻害方法
EP3277276B1 (en) Methods of administering glutaminase inhibitors
ES2822654T3 (es) Benzimidazol-2-aminas como inhibidores de mIDH1
CA2979142A1 (en) Therapeutic cyclic compounds as immunomodulators
JP2016505526A5 (https=)
WO2015033301A1 (en) 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives as immunomodulators
ME02121B (me) Kombinovana terapija sa parp inhibitorima
JP2017509672A5 (https=)
JP2017523991A5 (https=)
EP4031543A1 (en) Biaminoquinolines and nanoformulations for cancer treatment
JP2010514686A5 (https=)
JP2021522197A5 (https=)
JP2016538281A5 (https=)
JP2019526560A5 (https=)
WO2016111834A1 (en) Cox-2-targeting, platinum-containing conjugates and their use in the treatment of tumors and cancers
JP6422936B2 (ja) ５−ブロモ−インジルビン
JP2019524852A5 (https=)
WO2016181312A1 (en) Polycyclic epoxides and compositions thereof with anti-cancer activities
JP2014532751A5 (https=)
KR20210052322A (ko) 신규한 화합물 및 이를 포함하는 암 예방 또는 치료용 약학 조성물
CN106459011B (zh) 作为抗肿瘤化合物的σ-2受体配体药物缀合物、其合成方法及其用途
CN1367690A (zh) 使用五氟苯磺酰胺的综合疗法