JP2017508144A - 感情／気分障害のバイオマーカーとしてのソルチリンの使用 - Google Patents

感情／気分障害のバイオマーカーとしてのソルチリンの使用 Download PDF

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Publication number
JP2017508144A
JP2017508144A JP2016551166A JP2016551166A JP2017508144A JP 2017508144 A JP2017508144 A JP 2017508144A JP 2016551166 A JP2016551166 A JP 2016551166A JP 2016551166 A JP2016551166 A JP 2016551166A JP 2017508144 A JP2017508144 A JP 2017508144A
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Japan
Prior art keywords
sortilin
subject
bipolar disorder
sample
subjects
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JP2016551166A
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English (en)
Japanese (ja)
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JP2017508144A5 (enExample
Inventor
ジェプセン，ジェスパー，ルンドヘデ
ニクジャー，アンダース
モース，ニールズ，ピーター，オレ
ピーターセン，クロース，ムンク
オスターガード，ソレン，ダイネセン
グレラプ，サイモン
Original Assignee
ハー・ルンドベック・アクチエゼルスカベット
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Publication of JP2017508144A publication Critical patent/JP2017508144A/ja
Publication of JP2017508144A5 publication Critical patent/JP2017508144A5/ja
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/30—Psychoses; Psychiatry
    • G01N2800/304—Mood disorders, e.g. bipolar, depression
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016551166A 2014-02-12 2015-02-06 感情／気分障害のバイオマーカーとしてのソルチリンの使用 Pending JP2017508144A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201400075 2014-02-12
DKPA201400075 2014-02-12
PCT/EP2015/052506 WO2015121166A1 (en) 2014-02-12 2015-02-06 Use of sortilin as biomarker for affective/mood disorders

Publications (2)

Publication Number Publication Date
JP2017508144A true JP2017508144A (ja) 2017-03-23
JP2017508144A5 JP2017508144A5 (enExample) 2018-03-22

Family

ID=52462923

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016551166A Pending JP2017508144A (ja) 2014-02-12 2015-02-06 感情／気分障害のバイオマーカーとしてのソルチリンの使用

Country Status (6)

Country Link
US (1) US20160349276A1 (enExample)
EP (1) EP3105594A1 (enExample)
JP (1) JP2017508144A (enExample)
CN (1) CN105980858A (enExample)
HK (1) HK1232289A1 (enExample)
WO (1) WO2015121166A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3280441T3 (pl) 2015-04-07 2022-02-21 Alector Llc Przeciwciała przeciwko sortilinie i sposoby ich stosowania
US10849992B1 (en) 2015-04-07 2020-12-01 Alector Llc Methods of screening for sortilin binding antagonists
FR3057267A1 (fr) * 2016-10-11 2018-04-13 Centre National De La Recherche Scientifique - Cnrs - Procede de diagnostic/determination de l'efficacite de traitement de la depression
WO2019094757A1 (en) 2017-11-09 2019-05-16 The Trustees Of Columbia University In The City Of New York Pharmacological prophylactics against stress-induced affective disorders in females
WO2019094596A1 (en) * 2017-11-09 2019-05-16 The Trustees Of Columbia University In The City Of New York Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders
IL270214B2 (en) 2018-07-13 2024-07-01 Alector Llc Anti-sortilin antibodies and methods of using them
CN111351945B (zh) * 2020-03-18 2021-04-23 东南大学 维生素d结合蛋白作为标志物在精神疾病抑郁症诊断中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012085555A2 (en) * 2010-12-20 2012-06-28 Cambridge Enterprise Limited Biomarkers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3165537A1 (en) * 2008-12-19 2017-05-10 H. Lundbeck A/S Modulation of the vps 10-domain receptor family for the treatment of mental and behavioural disorders
GB0903417D0 (en) * 2009-02-27 2009-04-08 Cambridge Entpr Ltd Biomarkers
GB0922240D0 (en) * 2009-12-21 2010-02-03 Cambridge Entpr Ltd Biomarkers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012085555A2 (en) * 2010-12-20 2012-06-28 Cambridge Enterprise Limited Biomarkers

Also Published As

Publication number Publication date
EP3105594A1 (en) 2016-12-21
WO2015121166A1 (en) 2015-08-20
US20160349276A1 (en) 2016-12-01
HK1232289A1 (zh) 2018-01-05
CN105980858A (zh) 2016-09-28

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