JP2017507001A5 - - Google Patents
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- Publication number
- JP2017507001A5 JP2017507001A5 JP2016567459A JP2016567459A JP2017507001A5 JP 2017507001 A5 JP2017507001 A5 JP 2017507001A5 JP 2016567459 A JP2016567459 A JP 2016567459A JP 2016567459 A JP2016567459 A JP 2016567459A JP 2017507001 A5 JP2017507001 A5 JP 2017507001A5
- Authority
- JP
- Japan
- Prior art keywords
- barrier
- thermally stable
- fiber
- small amount
- population
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000835 fiber Substances 0.000 claims description 67
- 230000004888 barrier function Effects 0.000 claims description 58
- 229920001577 copolymer Polymers 0.000 claims description 12
- 230000002745 absorbent Effects 0.000 claims description 10
- 239000002250 absorbent Substances 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 10
- 238000002425 crystallisation Methods 0.000 claims description 9
- 230000008025 crystallization Effects 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 9
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 claims description 8
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 6
- 229920002463 poly(p-dioxanone) polymer Polymers 0.000 claims description 6
- 239000000622 polydioxanone Substances 0.000 claims description 6
- 229920001400 block copolymer Polymers 0.000 claims description 4
- 239000000178 monomer Substances 0.000 claims description 4
- 239000002904 solvent Substances 0.000 claims description 4
- YFHICDDUDORKJB-UHFFFAOYSA-N trimethylene carbonate Chemical compound O=C1OCCCO1 YFHICDDUDORKJB-UHFFFAOYSA-N 0.000 claims description 4
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 claims description 4
- 238000001523 electrospinning Methods 0.000 claims description 3
- 229920000642 polymer Polymers 0.000 claims description 3
- VPVXHAANQNHFSF-UHFFFAOYSA-N 1,4-dioxan-2-one Chemical compound O=C1COCCO1 VPVXHAANQNHFSF-UHFFFAOYSA-N 0.000 claims description 2
- 125000004122 cyclic group Chemical group 0.000 claims description 2
- 108010021753 peptide-Gly-Leu-amide Proteins 0.000 claims description 2
- 229920000139 polyethylene terephthalate Polymers 0.000 claims description 2
- 239000005020 polyethylene terephthalate Substances 0.000 claims description 2
- 206010019909 Hernia Diseases 0.000 claims 2
- 239000004721 Polyphenylene oxide Substances 0.000 claims 1
- 238000012377 drug delivery Methods 0.000 claims 1
- 230000000704 physical effect Effects 0.000 claims 1
- 229920000570 polyether Polymers 0.000 claims 1
- 230000035882 stress Effects 0.000 claims 1
- 230000008646 thermal stress Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000007792 addition Methods 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000000890 drug combination Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461933578P | 2014-01-30 | 2014-01-30 | |
| US61/933,578 | 2014-01-30 | ||
| PCT/US2015/013732 WO2015116917A1 (en) | 2014-01-30 | 2015-01-30 | Time-dependent synthetic biological barrier material |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020023988A Division JP7015332B2 (ja) | 2014-01-30 | 2020-02-17 | 時間依存性の合成生物学的バリア材料 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017507001A JP2017507001A (ja) | 2017-03-16 |
| JP2017507001A5 true JP2017507001A5 (cg-RX-API-DMAC7.html) | 2018-03-08 |
| JP6663858B2 JP6663858B2 (ja) | 2020-03-13 |
Family
ID=53757751
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016567459A Active JP6663858B2 (ja) | 2014-01-30 | 2015-01-30 | 時間依存性の合成生物学的バリア材料 |
| JP2020023988A Active JP7015332B2 (ja) | 2014-01-30 | 2020-02-17 | 時間依存性の合成生物学的バリア材料 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020023988A Active JP7015332B2 (ja) | 2014-01-30 | 2020-02-17 | 時間依存性の合成生物学的バリア材料 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US11739452B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3099316B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP6663858B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2937954C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015116917A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY168863A (en) | 2010-06-17 | 2018-12-04 | Univ Washington | Biomedical patches with aligned fibers |
| KR102044501B1 (ko) | 2012-09-21 | 2019-11-13 | 워싱톤 유니버시티 | 다수의 섬유를 포함하는 구조물을 생성하기 위한 시스템과 방법 및 그 구조물 |
| WO2015116912A1 (en) | 2014-01-30 | 2015-08-06 | Poly-Med. Inc. | Thermally and dimensionally stabilized electrospun compositions and methods of making same |
| US11058521B2 (en) | 2014-08-18 | 2021-07-13 | University of Central Oklahoma | Method and apparatus for improving osseointegration, functional load, and overall strength of intraosseous implants |
| US10932910B2 (en) | 2014-08-18 | 2021-03-02 | University of Central Oklahoma | Nanofiber coating to improve biological and mechanical performance of joint prosthesis |
| CN106492274B (zh) * | 2015-11-27 | 2019-07-02 | 广州迈普再生医学科技股份有限公司 | 组织修复用纤维膜及其制备方法和应用以及组织修复用制品 |
| US20200289249A1 (en) * | 2016-03-03 | 2020-09-17 | The Board Of Regents Of The University Of Texas System | Usage of melt spun polyolefin fine fibers for skin regeneration and mesh implantation |
| WO2017165651A1 (en) | 2016-03-23 | 2017-09-28 | University of Central Oklahoma | Method and apparatus to coat a metal implant with electrospun nanofiber matrix |
| CN109414524A (zh) * | 2016-05-12 | 2019-03-01 | 阿塞拉外科有限公司 | 组织替代材料和组织修复方法 |
| US10632228B2 (en) | 2016-05-12 | 2020-04-28 | Acera Surgical, Inc. | Tissue substitute materials and methods for tissue repair |
| EP3467176B1 (en) * | 2016-06-07 | 2021-08-18 | Fuence Co., Ltd. | Nanofiber structure constituted of polyhydroxyalkanoic acid, and non-woven fabric |
| CA3074733C (en) * | 2017-09-06 | 2022-06-21 | Tepha, Inc. | Calendered surgical meshes comprising polyhydroxyalkanoates |
| CA3227438A1 (en) | 2021-07-29 | 2023-02-02 | Acera Surgical, Inc. | Combined macro and micro-porous hybrid-scale fiber matrix |
| CA3227437A1 (en) | 2021-07-29 | 2023-02-02 | Acera Surgical, Inc. | Particle-form hybrid-scale fiber matrix |
| US12167853B2 (en) | 2021-09-07 | 2024-12-17 | Acera Surgical, Inc. | Non-woven graft materials for nerve repair and regeneration |
| WO2024226733A1 (en) * | 2023-04-25 | 2024-10-31 | Poly-Med, Inc. | Compositions and methods for nonwoven materials |
| GB202404518D0 (en) | 2024-03-28 | 2024-05-15 | Electrospinning Company Ltd | Composite material |
| WO2025226786A1 (en) * | 2024-04-25 | 2025-10-30 | Poly-Med, Inc. | Methods and compositions comprising wettable electrospun matrix |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4646741A (en) | 1984-11-09 | 1987-03-03 | Ethicon, Inc. | Surgical fastener made from polymeric blends |
| US5641501A (en) * | 1994-10-11 | 1997-06-24 | Ethicon, Inc. | Absorbable polymer blends |
| US6685956B2 (en) | 2001-05-16 | 2004-02-03 | The Research Foundation At State University Of New York | Biodegradable and/or bioabsorbable fibrous articles and methods for using the articles for medical applications |
| US7390452B2 (en) | 2002-03-08 | 2008-06-24 | Board Of Regents, The University Of Texas System | Electrospinning of polymer and mesoporous composite fibers |
| JP4496360B2 (ja) | 2003-04-24 | 2010-07-07 | 国立大学法人九州大学 | 医療用高分子ナノ・マイクロファイバー |
| US20050070930A1 (en) * | 2003-09-30 | 2005-03-31 | Gene W. Kammerer | Implantable surgical mesh |
| US20050148512A1 (en) | 2003-11-10 | 2005-07-07 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
| WO2005046516A2 (en) | 2003-11-10 | 2005-05-26 | Angiotech International Ag | Medical implants and anti-scarring agents |
| US7592277B2 (en) | 2005-05-17 | 2009-09-22 | Research Triangle Institute | Nanofiber mats and production methods thereof |
| US8128954B2 (en) | 2004-06-07 | 2012-03-06 | California Institute Of Technology | Biodegradable drug-polymer delivery system |
| US20060085063A1 (en) | 2004-10-15 | 2006-04-20 | Shastri V P | Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering |
| SG123727A1 (en) * | 2004-12-15 | 2006-07-26 | Univ Singapore | Nanofiber construct and method of preparing thereof |
| US10328032B2 (en) * | 2005-03-04 | 2019-06-25 | Biosurfaces, Inc. | Nanofibrous materials as drug, protein, or genetic release vehicles |
| US8771582B2 (en) * | 2005-03-04 | 2014-07-08 | BioScurfaces, Inc. | Electrospinning process for making a textile suitable for use as a medical article |
| WO2006116000A2 (en) * | 2005-04-26 | 2006-11-02 | Poly-Med, Inc. | Absorbable/biodegradable composite yarns and property-modulated surgical implants therefrom |
| US8048446B2 (en) * | 2005-05-10 | 2011-11-01 | Drexel University | Electrospun blends of natural and synthetic polymer fibers as tissue engineering scaffolds |
| US20080220054A1 (en) * | 2006-10-13 | 2008-09-11 | Shastri V Prasad | Modulation of drug release rate from electrospun fibers |
| US8105380B2 (en) | 2006-10-23 | 2012-01-31 | Stemedica Cell Technologies, Inc. | Cellular scaffold |
| US20100166854A1 (en) | 2006-10-30 | 2010-07-01 | Rutgers, The State University Of New Jersey | Electrospun matrices for delivery of hydrophilic and lipophilic compounds |
| US9011439B2 (en) | 2006-11-20 | 2015-04-21 | Poly-Med, Inc. | Selectively absorbable/biodegradable, fibrous composite constructs and applications thereof |
| CA2678483A1 (en) | 2007-02-12 | 2008-08-21 | Dow Global Technologies Inc. | Multi-layer composite structure |
| WO2009002984A2 (en) | 2007-06-26 | 2008-12-31 | Aegis Biosciences Llp | Stable and compatible polymer blends |
| US9358002B2 (en) * | 2008-04-01 | 2016-06-07 | Covidien Lp | Anchoring device |
| US20110143429A1 (en) * | 2008-04-30 | 2011-06-16 | Iksoo Chun | Tissue engineered blood vessels |
| US9492593B2 (en) | 2008-09-24 | 2016-11-15 | Poly-Med, Inc. | Absorbable, permeability-modulated barrier composites and applications thereof |
| CN102439210B (zh) | 2009-03-31 | 2015-12-16 | 3M创新有限公司 | 尺寸上稳定的非织造纤维幅材及其制造和使用方法 |
| WO2010143646A1 (ja) | 2009-06-09 | 2010-12-16 | 味の素株式会社 | 繊維構造体 |
| BR112012021246A2 (pt) * | 2010-02-23 | 2018-04-03 | 3M Innovative Properties Co | mantas fibrosas de não tecido dimensionalmente estáveis e métodos de preparo e uso das mesmas. |
| WO2012024390A2 (en) * | 2010-08-17 | 2012-02-23 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biohybrid composite scaffold |
| US9173978B2 (en) * | 2010-09-22 | 2015-11-03 | Ethicon, Inc. | Bioabsorbable polymeric compositions, processing methods, and medical devices therefrom |
| CA2868750C (en) | 2012-04-06 | 2020-08-04 | Poly-Med, Inc. | Polymeric mesh products, method of making and use thereof |
| US20130267972A1 (en) | 2012-04-06 | 2013-10-10 | Poly-Med, Inc. | Polymeric mesh products, method of making and use thereof |
| WO2014004746A2 (en) | 2012-06-26 | 2014-01-03 | Harvard Bioscience, Inc. | Methods and compositions for promoting the structural integrity of scaffolds for tissue engineering |
| WO2015116912A1 (en) | 2014-01-30 | 2015-08-06 | Poly-Med. Inc. | Thermally and dimensionally stabilized electrospun compositions and methods of making same |
-
2015
- 2015-01-30 CA CA2937954A patent/CA2937954C/en active Active
- 2015-01-30 US US15/115,650 patent/US11739452B2/en active Active
- 2015-01-30 JP JP2016567459A patent/JP6663858B2/ja active Active
- 2015-01-30 WO PCT/US2015/013732 patent/WO2015116917A1/en not_active Ceased
- 2015-01-30 EP EP15743098.4A patent/EP3099316B1/en active Active
- 2015-01-30 EP EP19205535.8A patent/EP3636276B1/en active Active
-
2020
- 2020-02-17 JP JP2020023988A patent/JP7015332B2/ja active Active
-
2023
- 2023-07-07 US US18/219,246 patent/US20240018707A1/en active Pending
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