JP2017506244A - ノルイボガイン及び関連化合物を用いた治療方法 - Google Patents

ノルイボガイン及び関連化合物を用いた治療方法 Download PDF

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Publication number
JP2017506244A
JP2017506244A JP2016552622A JP2016552622A JP2017506244A JP 2017506244 A JP2017506244 A JP 2017506244A JP 2016552622 A JP2016552622 A JP 2016552622A JP 2016552622 A JP2016552622 A JP 2016552622A JP 2017506244 A JP2017506244 A JP 2017506244A
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JP
Japan
Prior art keywords
norivogaine
patient
dose
pharmaceutically acceptable
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016552622A
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English (en)
Japanese (ja)
Inventor
フリードホフ，ローレンス
マイレ，エメリン
ワイス，ホルガー
Original Assignee
デメルクス，インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2014/019692 external-priority patent/WO2015126434A1/fr
Priority claimed from US14/195,822 external-priority patent/US9345711B2/en
Priority claimed from US14/485,514 external-priority patent/US20150231147A1/en
Application filed by デメルクス，インコーポレイテッド filed Critical デメルクス，インコーポレイテッド
Publication of JP2017506244A publication Critical patent/JP2017506244A/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Addiction (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016552622A 2014-02-18 2015-02-17 ノルイボガイン及び関連化合物を用いた治療方法 Pending JP2017506244A (ja)

Applications Claiming Priority (45)

Application Number Priority Date Filing Date Title
US201461941387P 2014-02-18 2014-02-18
US201461941390P 2014-02-18 2014-02-18
US61/941,387 2014-02-18
US61/941,390 2014-02-18
US201461945746P 2014-02-27 2014-02-27
US61/945,746 2014-02-27
USPCT/US2014/019692 2014-02-28
PCT/US2014/019692 WO2015126434A1 (fr) 2014-02-18 2014-02-28 Méthodes de traitement aigu et à long terme de la toxicomanie
US14/195,822 2014-03-03
US14/195,822 US9345711B2 (en) 2014-02-18 2014-03-03 Methods for acute and long-term treatment of drug addiction
US201461952731P 2014-03-13 2014-03-13
US201461952741P 2014-03-13 2014-03-13
US201461952733P 2014-03-13 2014-03-13
US201461952738P 2014-03-13 2014-03-13
US201461952744P 2014-03-13 2014-03-13
US201461952727P 2014-03-13 2014-03-13
US61/952,733 2014-03-13
US61/952,738 2014-03-13
US61/952,731 2014-03-13
US61/952,741 2014-03-13
US61/952,727 2014-03-13
US61/952,744 2014-03-13
US201462005855P 2014-05-30 2014-05-30
US201462005851P 2014-05-30 2014-05-30
US201462005847P 2014-05-30 2014-05-30
US201462005841P 2014-05-30 2014-05-30
US201462005858P 2014-05-30 2014-05-30
US62/005,851 2014-05-30
US14/292,632 US20150231146A1 (en) 2014-02-18 2014-05-30 Methods for acute and long-term treatment of drug addiction
US62/005,841 2014-05-30
US62/005,855 2014-05-30
US14/292,632 2014-05-30
US62/005,858 2014-05-30
US62/005,847 2014-05-30
US201462007346P 2014-06-03 2014-06-03
US62/007,346 2014-06-03
US201462024388P 2014-07-14 2014-07-14
US62/024,388 2014-07-14
US201462033538P 2014-08-05 2014-08-05
US62/033,538 2014-08-05
US201462035335P 2014-08-08 2014-08-08
US62/035,335 2014-08-08
US14/485,514 US20150231147A1 (en) 2014-02-18 2014-09-12 Methods for acute and long-term treatment of drug addiction
US14/485,514 2014-09-12
PCT/US2015/016186 WO2015126836A2 (fr) 2014-02-18 2015-02-17 Méthodes thérapeutiques faisant intervenir de la noribogaïne et des composés apparentés

Publications (1)

Publication Number Publication Date
JP2017506244A true JP2017506244A (ja) 2017-03-02

Family

ID=53879225

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016552622A Pending JP2017506244A (ja) 2014-02-18 2015-02-17 ノルイボガイン及び関連化合物を用いた治療方法

Country Status (10)

Country Link
EP (1) EP3107546A4 (fr)
JP (1) JP2017506244A (fr)
KR (1) KR20160124829A (fr)
CN (1) CN106413718A (fr)
AU (2) AU2015219172A1 (fr)
CA (2) CA3221251A1 (fr)
EA (1) EA201691656A2 (fr)
IL (1) IL247325A0 (fr)
TW (1) TW201534306A (fr)
WO (1) WO2015126836A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014143201A1 (fr) 2013-03-15 2014-09-18 Demerx, Inc. Procédé pour le traitement avec la noribogaïne de l'addiction de patients sous méthadone
US9561232B2 (en) 2014-02-18 2017-02-07 Demerx, Inc. Low dose noribogaine for treating nicotine addiction and preventing relapse of nicotine use
US9591978B2 (en) 2014-03-13 2017-03-14 Demerx, Inc. Methods and compositions for pre-screening patients for treatment with noribogaine
US9549935B2 (en) 2014-07-14 2017-01-24 Demerx, Inc. Methods and compositions for treating migraines using noribogaine
EP3915639B1 (fr) * 2014-11-26 2023-06-07 DemeRx, Inc. Procédés et compositions pour potentialiser l'action d'analgésiques opioïdes en utilisant des alcaloïdes de l'iboga

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE324897T1 (de) * 1994-07-25 2006-06-15 Nda Int Inc Verwendung von noribogain derivaten zur behandlung von chemischer abhängigkeit bei säugern
EP1327447B1 (fr) * 1997-09-04 2011-05-25 Novoneuron, Inc. Noribogaine utilisée pour le traitement de la douleur et de la toxomanie
US7220737B1 (en) * 1997-09-04 2007-05-22 Novoneuron, Inc Noribogaine in the treatment of pain and drug addiction
US20030153552A1 (en) * 2002-02-14 2003-08-14 Mash Deborah C. Method of treating chemical dependency in mammals and a composition therefor
MX2013000733A (es) * 2010-07-23 2013-05-30 Demerx Inc Composiciones de noribogaina.
WO2014143201A1 (fr) * 2013-03-15 2014-09-18 Demerx, Inc. Procédé pour le traitement avec la noribogaïne de l'addiction de patients sous méthadone

Also Published As

Publication number Publication date
KR20160124829A (ko) 2016-10-28
CA2977636A1 (fr) 2015-08-27
WO2015126836A2 (fr) 2015-08-27
CA2977636C (fr) 2024-01-02
AU2020267217A1 (en) 2020-12-03
EP3107546A2 (fr) 2016-12-28
AU2015219172A1 (en) 2016-09-29
CN106413718A (zh) 2017-02-15
EP3107546A4 (fr) 2017-10-25
TW201534306A (zh) 2015-09-16
AU2020267217B2 (en) 2022-04-07
IL247325A0 (en) 2016-09-29
CA3221251A1 (fr) 2015-08-27
EA201691656A2 (ru) 2017-03-31

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