CA2977636A1 - Methodes therapeutiques faisant intervenir de la noribogaine et des composes apparentes - Google Patents
Methodes therapeutiques faisant intervenir de la noribogaine et des composes apparentes Download PDFInfo
- Publication number
- CA2977636A1 CA2977636A1 CA2977636A CA2977636A CA2977636A1 CA 2977636 A1 CA2977636 A1 CA 2977636A1 CA 2977636 A CA2977636 A CA 2977636A CA 2977636 A CA2977636 A CA 2977636A CA 2977636 A1 CA2977636 A1 CA 2977636A1
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- CA
- Canada
- Prior art keywords
- noribogaine
- patient
- pharmaceutically acceptable
- acceptable salt
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 125000002813 thiocarbonyl group Chemical group *C(*)=S 0.000 description 1
- 229930192474 thiophene Natural products 0.000 description 1
- 229960001402 tilidine Drugs 0.000 description 1
- 208000037816 tissue injury Diseases 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- GTZCVFVGUGFEME-UHFFFAOYSA-N trans-aconitic acid Natural products OC(=O)CC(C(O)=O)=CC(O)=O GTZCVFVGUGFEME-UHFFFAOYSA-N 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- JOFWLTCLBGQGBO-UHFFFAOYSA-N triazolam Chemical compound C12=CC(Cl)=CC=C2N2C(C)=NN=C2CN=C1C1=CC=CC=C1Cl JOFWLTCLBGQGBO-UHFFFAOYSA-N 0.000 description 1
- 229960003386 triazolam Drugs 0.000 description 1
- 150000003852 triazoles Chemical class 0.000 description 1
- 206010044652 trigeminal neuralgia Diseases 0.000 description 1
- 229950009395 trimeperidine Drugs 0.000 description 1
- UVITTYOJFDLOGI-KEYYUXOJSA-N trimeperidine Chemical compound C=1C=CC=CC=1[C@]1(OC(=O)CC)C[C@H](C)N(C)C[C@H]1C UVITTYOJFDLOGI-KEYYUXOJSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA3221251A CA3221251A1 (fr) | 2014-02-18 | 2015-02-17 | Methodes therapeutiques faisant intervenir de la noribogaine et des com oses apparentes |
Applications Claiming Priority (45)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461941387P | 2014-02-18 | 2014-02-18 | |
| US201461941390P | 2014-02-18 | 2014-02-18 | |
| US61/941,390 | 2014-02-18 | ||
| US61/941,387 | 2014-02-18 | ||
| US201461945746P | 2014-02-27 | 2014-02-27 | |
| US61/945,746 | 2014-02-27 | ||
| USPCT/US2014/019692 | 2014-02-28 | ||
| PCT/US2014/019692 WO2015126434A1 (fr) | 2014-02-18 | 2014-02-28 | Méthodes de traitement aigu et à long terme de la toxicomanie |
| US14/195,822 US9345711B2 (en) | 2014-02-18 | 2014-03-03 | Methods for acute and long-term treatment of drug addiction |
| US14/195,822 | 2014-03-03 | ||
| US201461952733P | 2014-03-13 | 2014-03-13 | |
| US201461952727P | 2014-03-13 | 2014-03-13 | |
| US201461952738P | 2014-03-13 | 2014-03-13 | |
| US201461952731P | 2014-03-13 | 2014-03-13 | |
| US201461952744P | 2014-03-13 | 2014-03-13 | |
| US201461952741P | 2014-03-13 | 2014-03-13 | |
| US61/952,744 | 2014-03-13 | ||
| US61/952,738 | 2014-03-13 | ||
| US61/952,727 | 2014-03-13 | ||
| US61/952,741 | 2014-03-13 | ||
| US61/952,731 | 2014-03-13 | ||
| US61/952,733 | 2014-03-13 | ||
| US201462005841P | 2014-05-30 | 2014-05-30 | |
| US201462005847P | 2014-05-30 | 2014-05-30 | |
| US201462005858P | 2014-05-30 | 2014-05-30 | |
| US201462005855P | 2014-05-30 | 2014-05-30 | |
| US201462005851P | 2014-05-30 | 2014-05-30 | |
| US62/005,841 | 2014-05-30 | ||
| US62/005,851 | 2014-05-30 | ||
| US62/005,855 | 2014-05-30 | ||
| US62/005,858 | 2014-05-30 | ||
| US14/292,632 US20150231146A1 (en) | 2014-02-18 | 2014-05-30 | Methods for acute and long-term treatment of drug addiction |
| US14/292,632 | 2014-05-30 | ||
| US62/005,847 | 2014-05-30 | ||
| US201462007346P | 2014-06-03 | 2014-06-03 | |
| US62/007,346 | 2014-06-03 | ||
| US201462024388P | 2014-07-14 | 2014-07-14 | |
| US62/024,388 | 2014-07-14 | ||
| US201462033538P | 2014-08-05 | 2014-08-05 | |
| US62/033,538 | 2014-08-05 | ||
| US201462035335P | 2014-08-08 | 2014-08-08 | |
| US62/035,335 | 2014-08-08 | ||
| US14/485,514 | 2014-09-12 | ||
| US14/485,514 US20150231147A1 (en) | 2014-02-18 | 2014-09-12 | Methods for acute and long-term treatment of drug addiction |
| PCT/US2015/016186 WO2015126836A2 (fr) | 2014-02-18 | 2015-02-17 | Méthodes thérapeutiques faisant intervenir de la noribogaïne et des composés apparentés |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3221251A Division CA3221251A1 (fr) | 2014-02-18 | 2015-02-17 | Methodes therapeutiques faisant intervenir de la noribogaine et des com oses apparentes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2977636A1 true CA2977636A1 (fr) | 2015-08-27 |
| CA2977636C CA2977636C (fr) | 2024-01-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2977636A Active CA2977636C (fr) | 2014-02-18 | 2015-02-17 | Methodes therapeutiques faisant intervenir de la noribogaine et des composes apparentes |
| CA3221251A Pending CA3221251A1 (fr) | 2014-02-18 | 2015-02-17 | Methodes therapeutiques faisant intervenir de la noribogaine et des com oses apparentes |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3221251A Pending CA3221251A1 (fr) | 2014-02-18 | 2015-02-17 | Methodes therapeutiques faisant intervenir de la noribogaine et des com oses apparentes |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP3107546A4 (fr) |
| JP (1) | JP2017506244A (fr) |
| KR (1) | KR20160124829A (fr) |
| CN (1) | CN106413718A (fr) |
| AU (2) | AU2015219172A1 (fr) |
| CA (2) | CA2977636C (fr) |
| EA (1) | EA201691656A2 (fr) |
| IL (1) | IL247325A0 (fr) |
| TW (1) | TW201534306A (fr) |
| WO (1) | WO2015126836A2 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2942638A1 (fr) | 2013-03-15 | 2014-09-18 | Demerx, Inc. | Procede pour le traitement avec la noribogaine de l'addiction de patients sous methadone |
| US9561232B2 (en) | 2014-02-18 | 2017-02-07 | Demerx, Inc. | Low dose noribogaine for treating nicotine addiction and preventing relapse of nicotine use |
| US9591978B2 (en) | 2014-03-13 | 2017-03-14 | Demerx, Inc. | Methods and compositions for pre-screening patients for treatment with noribogaine |
| US9549935B2 (en) | 2014-07-14 | 2017-01-24 | Demerx, Inc. | Methods and compositions for treating migraines using noribogaine |
| WO2016086194A1 (fr) | 2014-11-26 | 2016-06-02 | Demerx, Inc. | Procédés et compositions pour potentialiser l'action d'analgésiques opioïdes en utilisant des alcaloïdes de l'iboga |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT804200E (pt) * | 1994-07-25 | 2006-09-29 | Nda Int Inc | Uso de derivados de noribogaina para tratamento de dependencia quimica em mamiferos |
| ES2435722T3 (es) * | 1997-09-04 | 2013-12-23 | Demerx, Inc. | Noribogaína en el tratamiento del dolor y de la adicción a drogas |
| US7220737B1 (en) * | 1997-09-04 | 2007-05-22 | Novoneuron, Inc | Noribogaine in the treatment of pain and drug addiction |
| US20030153552A1 (en) * | 2002-02-14 | 2003-08-14 | Mash Deborah C. | Method of treating chemical dependency in mammals and a composition therefor |
| WO2012012764A1 (fr) * | 2010-07-23 | 2012-01-26 | Demerx, Inc. | Compositions de noribogaïne |
| CA2942638A1 (fr) * | 2013-03-15 | 2014-09-18 | Demerx, Inc. | Procede pour le traitement avec la noribogaine de l'addiction de patients sous methadone |
-
2015
- 2015-02-17 WO PCT/US2015/016186 patent/WO2015126836A2/fr active Application Filing
- 2015-02-17 KR KR1020167025602A patent/KR20160124829A/ko unknown
- 2015-02-17 TW TW104105711A patent/TW201534306A/zh unknown
- 2015-02-17 CA CA2977636A patent/CA2977636C/fr active Active
- 2015-02-17 AU AU2015219172A patent/AU2015219172A1/en not_active Abandoned
- 2015-02-17 EA EA201691656A patent/EA201691656A2/ru unknown
- 2015-02-17 JP JP2016552622A patent/JP2017506244A/ja active Pending
- 2015-02-17 CN CN201580020072.5A patent/CN106413718A/zh active Pending
- 2015-02-17 CA CA3221251A patent/CA3221251A1/fr active Pending
- 2015-02-17 EP EP15751574.3A patent/EP3107546A4/fr active Pending
-
2016
- 2016-08-17 IL IL247325A patent/IL247325A0/en unknown
-
2020
- 2020-11-11 AU AU2020267217A patent/AU2020267217B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA3221251A1 (fr) | 2015-08-27 |
| TW201534306A (zh) | 2015-09-16 |
| EP3107546A2 (fr) | 2016-12-28 |
| JP2017506244A (ja) | 2017-03-02 |
| AU2015219172A1 (en) | 2016-09-29 |
| AU2020267217A1 (en) | 2020-12-03 |
| IL247325A0 (en) | 2016-09-29 |
| EP3107546A4 (fr) | 2017-10-25 |
| AU2020267217B2 (en) | 2022-04-07 |
| CA2977636C (fr) | 2024-01-02 |
| EA201691656A2 (ru) | 2017-03-31 |
| CN106413718A (zh) | 2017-02-15 |
| WO2015126836A2 (fr) | 2015-08-27 |
| KR20160124829A (ko) | 2016-10-28 |
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