JP2017502278A5 - - Google Patents
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- JP2017502278A5 JP2017502278A5 JP2016539206A JP2016539206A JP2017502278A5 JP 2017502278 A5 JP2017502278 A5 JP 2017502278A5 JP 2016539206 A JP2016539206 A JP 2016539206A JP 2016539206 A JP2016539206 A JP 2016539206A JP 2017502278 A5 JP2017502278 A5 JP 2017502278A5
- Authority
- JP
- Japan
- Prior art keywords
- laccer
- inhibitor
- subject
- pharmaceutical composition
- spms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361963738P | 2013-12-12 | 2013-12-12 | |
| US61/963,738 | 2013-12-12 | ||
| US201462049813P | 2014-09-12 | 2014-09-12 | |
| US62/049,813 | 2014-09-12 | ||
| PCT/US2014/070099 WO2015089443A2 (en) | 2013-12-12 | 2014-12-12 | Treating neurodegenerative disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017502278A JP2017502278A (ja) | 2017-01-19 |
| JP2017502278A5 true JP2017502278A5 (https=) | 2018-02-01 |
| JP6550388B2 JP6550388B2 (ja) | 2019-07-24 |
Family
ID=53371971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016539206A Expired - Fee Related JP6550388B2 (ja) | 2013-12-12 | 2014-12-12 | 神経変性疾患の治療 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9927437B2 (https=) |
| EP (1) | EP3080602B1 (https=) |
| JP (1) | JP6550388B2 (https=) |
| KR (1) | KR20160089528A (https=) |
| CN (1) | CN106030302B (https=) |
| CA (1) | CA2933554A1 (https=) |
| WO (1) | WO2015089443A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3445451B1 (en) | 2016-04-21 | 2021-08-18 | Baylor College of Medicine | Compositions and methods for the treatment of lysosomal storage disorders and disorders characterized by lysosomal dysfunction |
| JP7084689B2 (ja) * | 2016-12-08 | 2022-06-15 | 公益財団法人東京都医学総合研究所 | 脳組織の異常を伴う非ヒト動物の作製方法およびその利用 |
| WO2019030645A1 (en) * | 2017-08-08 | 2019-02-14 | Kashiv Pharma Llc | Pharmaceutical composition comprising eliglustat |
| CN112384204B (zh) | 2018-02-26 | 2023-03-14 | 安托瑞斯公司 | 致耐受性脂质体及其使用方法 |
| WO2019169317A1 (en) * | 2018-03-02 | 2019-09-06 | Stueve Olaf | Methods and compositions for treating natalizumab-associated progressive multifocal encephalopathy |
| WO2020061528A1 (en) * | 2018-09-21 | 2020-03-26 | University Of Connecticut | Compositions and methods to restore paternal ube3a gene expression in human angelman syndrome |
| CN114717232A (zh) * | 2020-12-22 | 2022-07-08 | 未来智人再生医学研究院(广州)有限公司 | 表达irf-1靶向抑制因子的多能干细胞及其衍生物与应用 |
| CN116794308A (zh) * | 2023-07-20 | 2023-09-22 | 中国药科大学 | β-1,4-半乳糖基转移酶1及其抑制剂在制备治疗急慢性肝病药物中的应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5700909A (en) * | 1993-07-30 | 1997-12-23 | The Regents Of The University Of California | Prosaposin and cytokine-derived peptides |
| EP1825853A2 (en) | 1998-07-27 | 2007-08-29 | Johns Hopkins University | Methods for treating conditions modulated by lactosyceramide |
| CA2548313A1 (en) * | 2003-12-23 | 2005-07-14 | Musc Foundation For Research Development | Methods and compositions for the prevention and treatment of inflammatory diseases or conditions |
| FR2869915B1 (fr) * | 2004-05-07 | 2006-08-18 | Merck Sante Soc Par Actions Si | Gm3 synthase, comme cible therapeutique dans les complications microvasculaires du diabete |
| US20090111812A1 (en) | 2004-06-14 | 2009-04-30 | Musc Foundation For Research Development | Methods for treating inflammatory disorders |
| US7572592B2 (en) * | 2005-01-31 | 2009-08-11 | Glycominds Ltd | Method for diagnosing multiple sclerosis |
| US8263576B2 (en) * | 2006-08-15 | 2012-09-11 | Mayo Foundation For Medical Education And Research | Non-natural sphingolipid analogs and uses thereof |
| EP2353004B1 (en) * | 2008-11-12 | 2018-01-03 | Yeda Research and Development Co. Ltd. | Diagnosis of multiple sclerosis |
| CA2817564A1 (en) * | 2010-11-18 | 2012-05-24 | Ronald K. Blackman | Preselection of subjects for therapeutic treatment based on hypoxic status |
| WO2012088133A1 (en) * | 2010-12-20 | 2012-06-28 | Stephen Davies | Methods for treating neurological conditions and compositions and materials therefor |
| CN102994554A (zh) * | 2011-09-15 | 2013-03-27 | 花王株式会社 | 神经酰胺和/或葡萄糖神经酰胺产生促进剂的制造方法 |
| CN103059160B (zh) * | 2011-10-20 | 2015-12-02 | 中国科学院上海药物研究所 | β-葡聚糖GFPBW1及其制备方法和用途 |
-
2014
- 2014-12-12 CA CA2933554A patent/CA2933554A1/en not_active Abandoned
- 2014-12-12 US US15/103,632 patent/US9927437B2/en active Active
- 2014-12-12 KR KR1020167018593A patent/KR20160089528A/ko not_active Abandoned
- 2014-12-12 CN CN201480075396.4A patent/CN106030302B/zh active Active
- 2014-12-12 JP JP2016539206A patent/JP6550388B2/ja not_active Expired - Fee Related
- 2014-12-12 EP EP14868919.3A patent/EP3080602B1/en active Active
- 2014-12-12 WO PCT/US2014/070099 patent/WO2015089443A2/en not_active Ceased
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