JP2017176467A - Liquid injector - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a liquid injector capable of reducing an amount of liquid to waste by minimizing a dead space of a liquid passage.SOLUTION: A liquid injector 1 includes: an outer casing 2 that has a liquid storage space in the inside, and a hole 253 extending in a central axis 12 direction and communicated with the liquid storage space, at a distal end on a position deviated from a central axis 12; a seal cap 3 provided rotationally about the central axis 12 for sealing the hole 253, at the distal end of the outer casing 2; a hub 6 mounted on the seal cap 3; and a needle tube 7. The seal cap 3 includes a hole 321 extending in the central axis 12 direction and communicated with the needle tube 7, in the distal end at a position deviated from the central axis 12. When the seal cap 3 is located at a first position, the hole 321 is sealed by the seal cap 3 and, when it is rotationally turned from the first position to be located at a second position, the hole 253 and the hole 321 are communicated.SELECTED DRAWING: Figure 13

Description

  The present invention relates to a liquid injection device.

  There is known a liquid injection device that can be applied to a prefilled syringe that contains a chemical solution or the like in advance (see, for example, Patent Document 1). The liquid injecting device described in Patent Document 1 includes an outer cylinder having a liquid storage space therein, a liquid introduction section that is formed to protrude from a tip portion of the outer cylinder, and has a flow channel that communicates with the liquid storage space inside. It is provided on the outer periphery of the liquid introduction part, and includes an inner plug that opens and closes the flow path, a hub attached to the inner plug, and a needle tube supported by the hub.

  The tip of the flow channel of the liquid introduction part is formed by two side holes that open to the side surface of the liquid introduction part. The inner plug has two lateral holes and two longitudinal grooves communicating with the lateral holes and the needle tube, and the first position seals the side hole and closes the flow path. And a second position for opening the flow path. Moreover, the liquid injection device has a protector that covers the needle tip of the needle tube in an unused state, and is configured such that when the protector is rotated, the inner plug is also rotated.

  In the liquid injection device in the unused state, the inner stopper is located at the first position, and in this case, each side hole of the liquid introduction part is sealed with the inner stopper. Then, when the protector is operated to rotate the inner stopper and move the inner stopper to the second position, the lateral hole of the inner stopper and the side hole of the liquid introduction part communicate with each other. The storage space communicates with the needle tube. Thereby, the liquid can be injected.

  However, in the liquid injection device described in Patent Document 1, two side holes are provided in the liquid introduction part, and two lateral holes are provided in the inner plug, and the outer cylinder is formed by the side holes and the lateral holes. Since the detour flow path that largely detours the central axis is formed, there is a problem that the dead space is increased and the amount of the chemical solution that is wasted increases.

  In addition, since two side holes are provided in the liquid introduction part, it is difficult to seal the side holes in an unused state, that is, to seal the liquid storage space, as compared with the case of one hole. is there.

International Publication No. 2013/038887

  An object of the present invention is to provide a liquid injection device that can reduce a dead space in a liquid flow path and reduce the amount of wasted liquid.

Such an object is achieved by the present inventions (1) to (9) below.
(1) an outer cylinder that has a liquid storage space inside, has a first hole that extends in the direction of the central axis at a position that is shifted from the central axis at the tip, and communicates with the liquid storage space;
A seal cap that is provided at the distal end of the outer cylinder so as to be rotatable around a central axis of the outer cylinder, and seals the first hole;
A needle hub attached to the seal cap;
A needle tube supported at the tip of the needle hub,
The seal cap has a second hole that extends in the direction of the central axis of the outer cylinder and communicates with the needle tube at a position shifted from the central axis of the outer cylinder at the tip of the seal cap. ,
When the seal cap is located at the first position, the first hole and the second hole do not communicate with each other, and the first hole is sealed by the seal cap;
When the seal cap rotates from the first position and is located at the second position, the first hole and the second hole communicate with each other, and the first hole and the second hole are in communication with each other. A liquid injection device, wherein the liquid storage space and the needle tube communicate with each other through two holes.

  (2) A lock cap is provided that sandwiches a part of the seal cap and a part of the outer cylinder from the central axis direction of the outer cylinder, and prevents the seal cap from being detached from the distal end portion of the outer cylinder. The liquid injection device according to (1) above.

  (3) A part of the needle hub, a part of the seal cap, and a part of the outer cylinder, and a part of the seal cap between a part of the needle hub and a part of the outer cylinder. The liquid according to (1), further including a lock cap that is sandwiched from the center axis direction of the outer cylinder and that prevents the needle hub and the seal cap from being detached from a distal end portion of the outer cylinder so as to be positioned in between. Injection device.

(4) The lock cap is provided to be rotatable around a central axis of the outer cylinder,
The seal cap and the lock cap have a first engagement portion and a second engagement portion that are engaged in a circumferential direction of the outer cylinder,
The liquid injection device according to (2) or (3), wherein the seal cap is rotated by rotating the lock cap.

(5) A protector that is rotatably provided around the central axis of the outer cylinder and covers the needle tube,
The lock cap and the protector have a third engagement portion and a fourth engagement portion that are engaged in a circumferential direction of the outer cylinder,
The liquid injection device according to (4), wherein the lock cap is rotated by rotating the protector.

  (6) The liquid injection device according to any one of (1) to (5), further including a restricting portion that restricts a distal end portion of the seal cap from spreading in a radial direction of the outer cylinder.

  (7) The liquid injection device according to any one of (1) to (6), wherein the seal cap has a concave portion on a tip surface.

(8) The outer cylinder has a cylindrical body,
Any one of the above (1) to (7), in which another member is disposed on the inner side of the outer periphery of the body part or at the same position as the outer periphery of the body part as viewed from the central axis direction of the outer cylinder. The liquid injection device as described.

  (9) The liquid injection device according to any one of (1) to (8), wherein the liquid injection device is a prefilled syringe.

  According to the present invention, the first hole and the second hole that constitute the flow path that allows the liquid storage space and the needle tube to communicate with each other extend in the direction of the central axis of the outer cylinder. The dead space can be reduced, thereby reducing the amount of wasted liquid.

It is a figure which applies the liquid injection device of this invention to a prefilled syringe, and shows the unused state (initial state). It is sectional drawing in the AA line of the liquid injection instrument shown in FIG. It is a perspective view which shows the hub of the liquid injection instrument shown in FIG. It is a perspective view which shows the lock cap of the liquid injection instrument shown in FIG. It is a perspective view which shows the seal cap of the liquid injection instrument shown in FIG. It is sectional drawing which shows the seal cap of the liquid injection instrument shown in FIG. It is sectional drawing which shows the outer cylinder of the liquid injection instrument shown in FIG. It is sectional drawing which shows the front-end | tip part of the liquid introduction part of the outer cylinder of the liquid injection instrument shown in FIG. It is sectional drawing of the liquid introduction part vicinity of the liquid injection instrument shown in FIG. It is sectional drawing of the liquid introduction part vicinity of the liquid injection instrument shown in FIG. It is sectional drawing of the liquid introduction part vicinity of the liquid injection instrument shown in FIG. FIG. 2 is a side view of the vicinity of a liquid introduction part of the liquid injection device shown in FIG. 1. It is sectional drawing of the liquid introduction part vicinity of the liquid injection instrument shown in FIG. It is sectional drawing of the liquid introduction part vicinity of the liquid injection instrument shown in FIG. It is sectional drawing in the BB line in the state where the seal cap of the liquid injection instrument shown in FIG. 12 was located in the 1st position. It is sectional drawing in the CC line in the state where the seal cap of the liquid injection instrument shown in FIG. 12 was located in the 1st position. It is sectional drawing in the BB line in the state which the seal cap of the liquid injection instrument shown in FIG. 12 located in the 2nd position.

  Hereinafter, the liquid injection device of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.

<First Embodiment>
FIG. 1 is a diagram showing an unused state (initial state) of the liquid injection device of the present invention applied to a prefilled syringe. FIG. 1A is a front view, and FIG. 1B is a side view. FIG. 2 is a cross-sectional view taken along line AA of the liquid injection device shown in FIG. FIG. 3 is a perspective view showing a hub of the liquid injection device shown in FIG. 1. FIG. 4 is a perspective view showing a lock cap of the liquid injection device shown in FIG. 1. FIG. 5 is a perspective view showing a seal cap of the liquid injection device shown in FIG. 1. FIG. 6 is a cross-sectional view showing a seal cap of the liquid injection device shown in FIG. 7 is a cross-sectional view showing an outer cylinder of the liquid injection device shown in FIG. FIG. 8 is a cross-sectional view showing the tip of the liquid introduction part of the outer cylinder of the liquid injection device shown in FIG. FIG. 9 is a cross-sectional view of the vicinity of the liquid introduction part of the liquid injection device shown in FIG. 10 is a cross-sectional view of the vicinity of the liquid introduction part of the liquid injection device shown in FIG. The cross section in FIG. 10 corresponds to the cross section in FIG. 2, and is 90 ° different from the cross section in FIG. 9 when viewed from the central axis direction of the outer cylinder. 11 is a cross-sectional view of the vicinity of the liquid introduction part of the liquid injection device shown in FIG. 12 is a side view of the vicinity of the liquid introduction part of the liquid injection device shown in FIG. 13 is a cross-sectional view of the vicinity of the liquid introduction part of the liquid injection device shown in FIG. 14 is a cross-sectional view of the vicinity of the liquid introduction part of the liquid injection device shown in FIG. The cross section of FIGS. 11-14 corresponds to the cross section of FIG. 15 is a cross-sectional view taken along line BB in a state where the seal cap of the liquid injection device shown in FIG. 12 is located at the first position. FIG. 16 is a cross-sectional view taken along line CC in a state where the seal cap of the liquid injection device shown in FIG. 12 is located at the first position. 17 is a cross-sectional view taken along line B-B in a state where the seal cap of the liquid injection device shown in FIG. 12 is located at the second position.

  In the following, for convenience of explanation, the lower side in FIGS. 1 to 17 is referred to as a “base end” and the upper side is referred to as a “tip”. Moreover, the up-down direction in FIGS. 1-17 is the "center axial direction", "axial direction", and "longitudinal direction" of a liquid injection instrument and an outer cylinder.

  A liquid injection device 1 shown in FIG. 1 and FIG. 2 is a medical device used when injecting a liquid into a living body. In this embodiment, the liquid injection device 1 is a prefilled syringe filled with a liquid such as a chemical solution in advance. Examples of the liquid include protein medical products such as antibodies, peptide medical products such as hormones, nucleic acid medical products, cell medicines, blood products, vaccines for preventing various infectious diseases, anticancer agents, anesthetics, medical treatments, etc. Narcotics, antibiotics, steroids, proteolytic enzyme inhibitors, sugar injections such as heparin and glucose, electrolyte correction injections such as sodium chloride and potassium lactate, vitamins, fat emulsions, contrast agents, stimulants, etc. Is mentioned.

  As shown in FIG. 1 and FIG. 2, the liquid injection device 1 is installed in an outer cylinder (syringe outer cylinder) 2 that can be filled with a liquid, and the outer cylinder 2, along the direction of the central axis 12 of the outer cylinder 2. A gasket 8 that can slide, a plunger 8 (operation member) that moves the gasket 8 along the direction of the central axis 12 of the outer cylinder 2, that is, a pressing operation, a seal cap 3, a lock cap 4, and a needle tube 7. And an injection needle 5 composed of a hub (needle hub) 6 and a protector 11 covering the needle tube 7. The gasket 8 is connected to the tip of the plunger 9.

  As shown in FIGS. 7 and 8, the outer cylinder 2 is formed of a bottomed cylindrical member. That is, the outer cylinder 2 includes a bottom portion 21 provided at the distal end portion, and a cylindrical trunk portion 22 formed of a side wall standing from the edge portion of the bottom portion 21 toward the proximal end direction. 22 has an opening at the base end. The bottom 21 has a mortar shape. A liquid storage space 24 is formed in the outer cylinder 2, that is, in a portion surrounded by the outer cylinder 2 and the gasket 8. The liquid storage space 24 can be filled with a liquid. In the present embodiment, the liquid is stored in advance.

  Moreover, although the scale (not shown) which shows the liquid quantity is attached | subjected to the outer peripheral surface of the outer cylinder 2, the said scale may be abbreviate | omitted.

  Moreover, it is preferable that the outer cylinder 2 is substantially transparent in order to ensure internal visibility. Thereby, the liquid can be visually recognized.

  A flange 23 is integrally formed on the outer periphery of the base end portion of the outer cylinder 2. When the plunger 9 is moved relative to the outer cylinder 2, the operation can be performed by putting a finger on the flange 23.

  In addition, a liquid guide portion 25 that is reduced in diameter with respect to the body portion 22 of the outer cylinder 2 and protrudes toward the distal end is integrally formed at the center portion of the bottom portion 21 at the distal end portion of the outer cylinder 2. .

  The liquid guide part 25 has a cylindrical shape, and a flow path 251 through which the liquid passes is formed. The flow path 251 extends in the direction of the central axis 12 of the outer cylinder 2, communicates with the liquid storage space 24, and is open at the tip of the liquid guide portion 25.

  More specifically, a hole 252 that is arranged coaxially with the central axis 12 and extends in the direction of the central axis 12 is formed in the liquid introduction part 25. The hole 252 is formed from the proximal end of the liquid introducing portion 25 to the vicinity of the distal end, the distal end is closed, opens to the proximal end of the liquid introducing portion 25, and communicates with the liquid storage space 24. In addition, a hole (first hole) 253 that is disposed at a position shifted from the central axis 12 and extends in the direction of the central axis 12 is formed at the tip of the liquid introduction part 25. The hole 253 is open to the tip of the liquid introduction part 25. The hole 252 and the hole 253 communicate with each other at the distal end portion of the hole 252 and the proximal end portion of the hole 253, and the flow path 251 is configured by the hole 252 and the inner cavity of the hole 253.

  In this embodiment, the side of the hole 252 and the side of the hole 253 communicate with each other. However, the present invention is not limited to this. For example, the tip of the hole 252 and the base end of the hole 253 communicate with each other. Good.

  Further, a ring-shaped rib 254 is formed along the circumferential direction on the outer peripheral portion of the tip portion of the liquid introduction portion 25. The ribs 254 protrude in the radial direction and the distal end direction of the liquid introduction part 25. The rib 254 may protrude only in the tip direction of the liquid introduction part 25.

  Further, a ring-shaped rib 255 is formed along the circumferential direction on the outer peripheral portion of the base end portion of the liquid introduction portion 25. The rib 255 protrudes in the radial direction of the liquid introduction part 25.

  In addition, a plurality of ring-shaped (three in the present embodiment) ribs 256 along the circumferential direction are formed in the outer peripheral portion of the liquid introduction portion 25 and between the ribs 254 and 255. Has been. The ribs 256 are arranged at equal intervals along the direction of the central axis 12. In addition, the rib 256 protrudes in the radial direction of the liquid introduction part 25. The rib 256 can reduce the frictional resistance between the liquid introduction part 25 and the seal cap 3, and can be easily and reliably turned when the seal cap 3 is turned with respect to the liquid introduction part 25. . In the figure, a state in which the rib 256 bites into the seal cap 3 formed of an elastic member is shown.

  In addition, the rib 255 is the longest among the sizes of the ribs 254, 255, and 256, that is, the protruding length in the radial direction of the liquid introduction part 25.

  Further, other members to be described later, that is, a seal cap 3, a lock cap 4, an injection needle 5 composed of a needle tube 7 and a hub 6, a gasket 8, a plunger 9, and a protector 11 are provided with a central shaft 12. When viewed from the direction, the outer cylinder body 22 is disposed on the inner side or at the same position as the outer periphery of the body section 22.

  As shown in FIGS. 5 and 6, the seal cap 3 includes a bottomed cylindrical main body portion 31 having a bottom portion 32 at a distal end portion, and a proximal end side member 33 provided at a proximal end portion of the main body portion 31. Have. As will be described later, the constituent material of the seal cap 3 is not particularly limited, but in the present embodiment, a case where the seal cap 3 is made of an elastic material will be described as an example.

  As shown in FIGS. 9 and 10, the seal cap 3 is installed at the distal end portion of the outer cylinder 2, that is, the liquid introduction portion 25 so as to be rotatable (displaceable) around the central axis 12.

  The seal cap 3 has a function of sealing the hole 253 of the outer cylinder 2. The first position where the hole 253 is sealed by the seal cap 3 (see FIG. 13), the hole 253, and the seal cap It is comprised so that it can be located in the 2nd position (refer FIG. 14) which the hole 321 mentioned later of 3 communicated. In the unused state of the liquid injection device 1, that is, the initial state, the seal cap 3 is located at the first position.

  A hole (second hole) 321 through which a liquid passes is formed inside the bottom 32 of the seal cap 3. The hole 321 is disposed at a position shifted from the central axis 12 and extends in the direction of the central axis 12. Moreover, the hole 321 is open | released at the front-end | tip and base end of the bottom part 32, respectively, and is connected with the needle tube 7 of the injection needle 5 via the flow path 62 mentioned later.

  In addition, a concave portion 322 that is open to the tip of the bottom 32 is formed on the tip of the bottom 32. Thereby, for example, even when the bottom portion 32 is deformed and the flow path 62 is closed, the hole 321 and the needle tube 7 can be communicated with each other through the concave portion 322.

  The shape of the concave portion 322 is not particularly limited, but in the present embodiment, the concave portion 322 has a circular shape in plan view, that is, when viewed from the direction of the central axis 12.

  In addition, a ring-shaped groove 323 is formed at the base end portion of the bottom portion 32 so as to open to the base end of the bottom portion 32 and along the circumferential direction of the inner peripheral portion of the main body portion 31. Further, when viewed from the direction of the central axis 12, the hole 321, the concave portion 322, and the flow path 62 are disposed on the inner side of the groove 323, that is, on the central axis 12 side of the inner periphery of the groove 323.

  The groove 323 is disposed at a position corresponding to the rib 254 of the outer cylinder 2, has a shape corresponding to the rib 254, and is slightly smaller than the rib 254. The rib 254 is inserted into the groove 323 with the groove 323 elastically deformed and slightly expanded. As a result, the bottom 32 expands in the radial direction of the outer cylinder 2 and the position of the hole 321 is shifted, and when the seal cap 3 is positioned at the second position, the hole 321 and the hole 253 do not communicate with each other. This can be prevented. Therefore, the groove 323 and the rib 254 constitute a restricting portion that restricts the distal end portion of the seal cap 3, that is, the bottom portion 32 from spreading in the radial direction of the outer cylinder 2.

  The base end side member 33 includes a plate-like portion 331 provided over the circumference of the base end portion of the main body portion 31 and a pair of walls protruding in the base end direction from the outer circumference of the plate-like portion 331. Part 336.

  The plate-like part 331 protrudes in the radial direction of the main body part 31. The plate-shaped portion 331 is disposed at a position opposed to the pair of small diameter portions 332 disposed through the central axis 12 and the pair of small diameter portions 332 disposed at positions opposed to the central axis 12 when viewed from the direction of the central axis 12. It has a pair of large-diameter portions 333 having a protruding length longer than that of the portion 332. Further, when viewed from the direction of the central axis 12, the small diameter portions 332 and the large diameter portions 333 are alternately arranged at 90 ° intervals at the central angle. As seen from the direction of the central axis 12, the outer peripheral portion of the small diameter portion 332 and the outer peripheral portion of the large diameter portion 333 each have an arc shape, and the radius of curvature of the large diameter portion 333 is the radius of curvature of the small diameter portion 332. Bigger than.

  Each wall portion 336 is formed along the outer periphery of the corresponding large-diameter portion 333, and has an arc shape when viewed from the direction of the central axis 12.

  As shown in FIG. 13, when the seal cap 3 is located at the first position, the hole 253 of the outer cylinder 2 and the hole 321 of the seal cap 3 do not communicate with each other, and the hole 253 is sealed by the seal cap 3. It has been stopped. In this case, in the present embodiment, the hole 253 and the hole 321 are shifted by 180 ° when viewed from the direction of the central axis 12.

  Then, as shown in FIG. 14, when the seal cap 3 is rotated by a predetermined angle from the first position, 180 ° in the present embodiment, and is located at the second position, the holes 253, 321, The liquid storage space 24 and the needle tube 7 communicate with each other through the holes 252, 253, 321 and the like.

  As shown in FIGS. 9, 10, and 12, a lock cap 4 is attached to the outer peripheral portion of the outer cylinder 2 and the hub 6. In this embodiment, the lock cap 4 is installed integrally with the seal cap 3 so as to be rotatable around the central axis 12. The lock cap 4 sandwiches a part of the hub 6, a part of the seal cap 3, and a part of the outer cylinder 2 from the direction of the central axis 12, and the hub 6 and the seal cap 3 from the tip of the outer cylinder 2. Has the function of preventing the detachment.

  As shown in FIG. 4, the lock cap 4 has an arc shape when viewed from the direction of the central axis 12, and a pair of first sandwiching portions 41 disposed at positions opposed to each other via the central axis 12. And a pair of second sandwiching portions 42 disposed at positions facing each other via the central shaft 12, and a connecting portion 43 that couples the first sandwiching portion 41 and the second sandwiching portion 42. .

  Each first clamping part 41 is arranged on the tip side from each second clamping part 42. Further, when viewed from the direction of the central axis 12, the first clamping parts 41 and the second clamping parts 42 are alternately arranged at 90 ° intervals at the central angle.

  In addition, a pair of projecting portions 411 projecting in the proximal direction is formed on the base end surface of each first sandwiching portion 41. Each protrusion 411 is disposed in the vicinity of the connecting portion 43.

  Further, a claw 421 that protrudes toward the central axis 12 is formed on the inner peripheral portion of each second clamping portion 42.

  As shown in FIGS. 9 and 10, the claw 421 of the second clamping part 42 of the lock cap 4 and the rib 255 of the liquid introduction part 25 of the outer cylinder 2 are engaged in the direction of the central axis 12. In this case, the claw 421 is engaged with the proximal end side of the rib 255. Further, the first clamping portion 41 of the lock cap 4 and the flange 61 of the hub 6 are engaged in the direction of the central axis 12. In this case, the first clamping part 41 is engaged with the distal end side of the flange 61. Further, the plate-like portion 331 of the base end side member 33 of the seal cap 3 is disposed between the first sandwiching portion 41 and the rib 255 and is engaged with the first sandwiching portion 41 and the rib 255 in the direction of the central axis 12. doing.

  In this way, the flange 61 of the hub 6, the plate-like portion 331 of the seal cap 3, and the rib 255 of the outer cylinder 2 are arranged in this order from the distal end side to the proximal end side. , Sandwiched from the direction of the central axis 12.

  Thereby, the hub 6 and the seal cap 3 are prevented from being detached from the distal end portion of the outer cylinder 2. In particular, the seal cap 3 made of an elastic material has a plate-like portion 331 sandwiched between the first sandwiching portion 41 and the rib 255, so that the seal cap 3 is detached from the distal end portion of the outer cylinder 2. It can prevent more reliably.

As shown in FIGS. 2 and 11, the injection needle 5 is attached to the outer peripheral portion of the main body 31 of the seal cap 3. In this embodiment, the injection needle 5 is installed integrally with the seal cap 3 so as to be rotatable around the central axis 12.
The injection needle 5 has a hub 6 and a needle tube 7 that is supported and fixed to the tip of the hub 6.

  The hub 6 is composed of a cylindrical member, and the seal cap 3 is inserted into the proximal end portion of the inner cavity portion thereof. As a result, the hub 6 is attached to the main body 31 of the seal cap 3. At this time, the inner surface of the hub 6 and the outer surface of the bottom 32 of the main body 31 can be brought into close contact with each other, and the liquid tightness of the flow path through which the liquid flows can be maintained.

  In addition, a flow path 62 for communicating the hole 321 and the needle tube 7 is formed between the inner surface of the hub 6 and the tip surface of the bottom portion 32.

  As shown in FIG. 3, a pair of plate-like flanges 61 are integrally formed on the outer periphery of the base end portion of the hub 6. The flanges 61 are arranged at positions facing each other with the central axis 12 as viewed from the direction of the central axis 12. The base end portion of the hub 6 including the flanges 61 is in contact with the plate-like portion 331 of the seal cap 3.

  A hollow needle tube 7 is inserted at the distal end of the inner cavity of the hub 6. The needle tube 7 is fixed to the hub 6 in a liquid-tight manner by, for example, a method using an adhesive or a solvent. The needle tube 7 thus fixed has a lumen communicating with the lumen of the hub 6.

  A sharp needle tip is formed at the tip of the needle tube 7. Thereby, the target site can be punctured and the liquid can be injected in that state. The shape of the needle tip is not particularly limited, and preferably has a shape having a blade surface inclined at a predetermined angle with respect to the central axis 12, that is, the axis of the needle tube 7, as shown in FIG.

  As shown in FIGS. 1, 2, and 12, a protector 11 is attached to the hub 6. In this embodiment, the protector 11 is installed integrally with the seal cap 3 so as to be rotatable around the central axis 12. In addition, the injection needle 5 is arranged inside the protector 11 in the mounted state, and the protector 11 can cover the distal end side of the outer cylinder 2, that is, at least the needle tube 7 of the injection needle 5.

  The protector 11 has a bottomed cylindrical shape having a bottom at the tip. That is, the tip of the protector 11 is closed. Therefore, the protector 11 also has a function of keeping the sterility of the needle tube 7, that is, a function of blocking bacteria from entering between the needle tube 7 and the protector 11.

  Further, a pair of projecting portions (fourth engaging portions) 111 are formed at the base end portion of the protector 11 so as to be opposed to each other through the central shaft 12 when viewed from the central shaft 12 direction. Yes. The protrusion 111 protrudes in the proximal direction. In FIGS. 1 and 12, only one protrusion 111 is visible.

  The constituent materials of the outer cylinder 2, the lock cap 4, the hub 6, the plunger 9, and the protector 11 are not particularly limited. For example, a cyclic olefin polymer (for example, ethylene and tetracyclo [4.4.0. 12.5.17.10] -3-dodecene copolymer or hydrogen-based cycloolefin polymer), polyvinyl chloride, polyethylene, polypropylene, polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin , Acrylonitrile-butadiene-styrene copolymer, polyester such as polyethylene terephthalate, butadiene-styrene copolymer, polyamide (for example, nylon 6, nylon 6,6, nylon 6,10, nylon 12), polyethersulfone, polysulfone Various types like Butter, and the like. Among them, a cyclic olefin polymer (for example, ethylene and tetracyclo [4.4.0.12.5.17.10] -3-dodecene copolymer, hydrogen-based cycloolefin polymer, etc.) in that molding is easy. ), Polypropylene, poly- (4-methylpentene-1), polyethersulfone, and polysulfone are preferred.

  The constituent material of the needle tube 7 is not particularly limited, and examples thereof include a metal material such as stainless steel, aluminum or aluminum alloy, titanium or titanium alloy, and the like.

  The elastic material constituting the gasket 8 is not particularly limited. For example, various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, and silicone rubber, polyurethane, polyester Examples thereof include elastic materials such as various thermoplastic elastomers such as polyamides, polyamides, olefins, and styrenes, or mixtures thereof.

  Further, the constituent material of the seal cap 3 is not particularly limited. For example, in addition to the resins mentioned as the constituent material of the outer cylinder 2, resins such as HDPE (high density polyethylene) and LDPE (low density polyethylene), The elastic material mentioned as a constituent material of the said gasket 8 is mentioned, Among these, an elastic material is preferable. In the illustrated configuration, the seal cap 3 is made of an elastic material. In addition, only the part which contact | connects the seal cap 3 with a liquid may be comprised with an elastic material, and the other part may be comprised with resin.

  In the liquid injection device 1, the protector 11, the lock cap 4, the seal cap 3, and the hub 6 are integrally configured to be rotatable in both forward and reverse directions around the central axis 12.

  That is, as shown in FIG. 12, the protruding portion 111 of the protector 11 and the first clamping portion 41 of the lock cap 4 are engaged in the circumferential direction of the outer cylinder 2. Thereby, even when the protector 11 is rotated in either the forward or reverse direction, the lock cap 4 is rotated. Accordingly, the portion of the first clamping portion 41 that comes into contact with the protruding portion 111 constitutes a third engaging portion.

  Further, the second clamping part 42 of the lock cap 4 and the wall part 336 of the seal cap 3 are engaged in the circumferential direction of the outer cylinder 2. Thereby, even when the lock cap 4 is rotated in either the forward or reverse direction, the seal cap 3 is rotated. Accordingly, the portion of the wall portion 336 that contacts the second clamping portion 42 constitutes a first engaging portion. Moreover, the part which contact | abuts the wall part 336 of the 2nd clamping part 42 comprises the 2nd engaging part.

  As shown in FIG. 15, the protruding portion 411 of the first clamping portion 41 of the lock cap 4 and the flange 61 of the hub 6 are engaged in the circumferential direction of the outer cylinder 2. Thereby, even if the lock cap 4 is rotated in either the forward or reverse direction, the hub 6 is rotated. Therefore, the protrusion part 411 comprises the 5th engaging part. Moreover, the part which contact | abuts the protrusion part 411 of the flange 61 comprises the 6th engaging part.

  In this way, the protector 11, the lock cap 4, the seal cap 3, and the hub 6 are integrally rotated when the protector 11 is rotated in any of the forward and reverse directions around the central axis 12.

  As shown in FIG. 16, a pair of concave portions 257 and 258 are formed on the outer peripheral portion of the rib 255 of the liquid introduction portion 25 of the outer cylinder 2. The recesses 257 and 258 are arranged at positions facing each other through the central axis 12 when viewed from the direction of the central axis 12.

  In addition, a pair of convex portions 422 and 423 are formed on the inner peripheral portion of the pair of second clamping portions 42 of the lock cap 4. The convex portions 422 and 423 are arranged at positions facing each other through the central axis 12 when viewed from the direction of the central axis 12.

  When not in use, that is, when the seal cap 3 is located at the first position, the convex portion 422 is disposed in the concave portion 257 and the convex portion 423 is disposed in the concave portion 258.

  In this case, regarding the two side surfaces 2571 and 2572 of the recess 257, the right side surface 2571 in FIG. 16 is an inclined surface, and the left side surface 2572 in FIG. 16 is a vertical surface.

  Further, regarding the two side surfaces 4221 and 4222 of the convex portion 422, the right side surface 4221 in FIG. 16 is a vertical surface, and the left side surface 4222 in FIG. 16 is an inclined surface.

  Further, regarding the two side surfaces 2581 and 2582 of the recess 258, the right side surface 2581 in FIG. 16 is an inclined surface, and the left side surface 2582 in FIG. 16 is a vertical surface.

  Further, regarding the two side surfaces 4231 and 4232 of the convex portion 423, the right side surface 4231 in FIG. 16 is a vertical surface, and the left side surface 4232 in FIG. 16 is an inclined surface.

  Thus, for the recess 257 and the protrusion 422, one vertical surface and the other inclined surface are adjacent to each other. Similarly, for the recess 258 and the protrusion 423, one vertical surface and the other Are adjacent to each other.

  Thereby, the lock cap 4 can be rotated in both forward and reverse directions around the central axis 12 with respect to the outer cylinder 2.

  On the other hand, as shown in FIG. 17, when the lock cap 4 is rotated 180 ° with respect to the outer cylinder 2 from the unused state and the seal cap 3 is located at the second position, The part 423 is arranged, and the convex part 422 is arranged in the concave part 258.

  In this case, regarding the two side surfaces 4231 and 4232 of the convex portion 423, the right side surface 4232 in FIG. 17 is an inclined surface, and the left side surface 4231 in FIG. 17 is a vertical surface.

  As for the two side surfaces 4221 and 4222 of the convex portion 422, the right side surface 4222 in FIG. 17 is an inclined surface, and the left side surface 4221 in FIG. 17 is a vertical surface.

  As described above, the concave portion 257 and the convex portion 423 are adjacent to each other on the left side in FIG. 17, and similarly, the concave portion 258 and the convex portion 422 are illustrated on the left side in FIG. , The mutually perpendicular surfaces are adjacent to each other.

  As a result, the lock cap 4 cannot rotate in either the forward or reverse direction around the central axis 12 with respect to the outer cylinder 2. That is, the seal cap 3 is restricted from rotating in both forward and reverse directions around the central axis 12 from the second position. Thereby, the state in which the liquid storage space 24 and the needle tube 7 in the liquid injection device 1 communicate with each other is reliably maintained.

Next, an operation method of the liquid injection device 1 will be described.
[1] First, an unused liquid injection device 1 shown in FIGS. 1 and 2 is prepared. As shown in FIG. 13, in the liquid injection device 1, the seal cap 3 is located at the first position, whereby the flow path 251 of the liquid introduction part 25 is closed, that is, the liquid introduction part. The 25 holes 253 and the hole 321 of the seal cap 3 are blocked.

  [2] Next, the protector 11 is held with one hand, and the outer cylinder 2 is held with the other hand. Then, as it is, the protector 11 is rotated in a predetermined direction around the central axis 12 to rotate the protector 11. Thereby, the protector 11, the lock cap 4, the seal cap 3, and the hub 6 rotate integrally.

  Then, when the protector 11 is rotated by a predetermined angle, 180 ° in this embodiment, as shown in FIG. 14, the seal cap 3 is located at the second position. Thereby, the hole 253 of the liquid introduction part 25 and the hole 321 of the seal cap 3 communicate with each other, and the flow path 251 of the liquid introduction part 25 is opened. That is, the liquid storage space 24 and the needle tube 7 communicate with each other through the holes 252, 253, 321 and the like.

  [3] Next, the protector 11 is removed. Thereby, the needle tip of the injection needle 5 is exposed. Thereafter, the needle tip of the injection needle 5 is punctured into the target site, and the plunger 9 is pressed while in the punctured state. Thereby, the liquid can be injected.

  As described above, according to the liquid injection device 1, the holes 252, 253, and 321 constituting the flow path that allows the liquid storage space 24 and the needle tube 7 to communicate with each other extend in the direction of the central axis 12. In the liquid flow path, the dead space can be reduced, thereby reducing the amount of liquid that is wasted.

  In the liquid injection device 1, the protector 11 protects the needle tip of the needle tube 7 of the injection needle 5 and is not a rubber stopper. Thereby, the puncture resistance and coring which are generated when the rubber stopper is punctured with the needle tip of the injection needle 5 can be prevented, and the liquid injection device 1 can be easily manufactured. In addition, when the needle tube 7 is 31G or thinner, if the needle tip of the needle tube 7 is to be protected with a rubber plug, problems such as the needle tube 7 being bent or the needle tip being crushed when puncturing the rubber plug occur. There is a fear. Such a problem can be prevented in the liquid injection device 1.

  Further, in the liquid introduction part 25, the hole that communicates with the liquid storage space 24 and opens to the outside is a single hole 253, so that the hole 253 can be easily and reliably sealed in an unused state. The liquid storage space 24 can be easily and reliably sealed.

  As mentioned above, although the liquid injection device of the present invention has been described based on the illustrated embodiment, the present invention is not limited to this, and each part is replaced with an arbitrary configuration that can exhibit the same function. can do. Moreover, arbitrary components may be added.

  In the above embodiment, the outer cylinder is preliminarily filled with the liquid. However, the present invention is not limited to this. For example, the outer cylinder is not initially filled with the liquid, and the outer cylinder is filled later. The liquid may be filled and used.

  In the present invention, the gasket may be omitted. In this case, for example, the distal end portion of the plunger is configured to function as a gasket.

DESCRIPTION OF SYMBOLS 1 ... Liquid injection device 2 ... Outer cylinder 3 ... Seal cap 4 ... Lock cap 5 ... Injection needle 6 ... Hub 7 ... Needle tube 8 ... Gasket 9 ... Plunger 11 ... Protector 12 ... Center shaft 21 ... Bottom 22 ... Trunk 23 ... Flange 24 ... Liquid storage space 25 ... Liquid introduction part 31 ... Body part 32 ... Bottom 33 ... Base end side member 41 ... First clamping part 42 ... Second clamping part 43 ... Connection part 61 ... Flange 62 ... Channel 111 ... Projection part 251 ... Channel 252 ... Hole 253 ... Hole 254 ... Rib 255 ... Rib 256 ... Rib 257 ... Recess 258 ... Recess 321 ... Hole 322 ... Recess 323 ... Groove 331 ... Plate-shaped part 332 ... Small diameter part 333 ... Large diameter part 336 ... Wall part 411 ... Projection part 421 ... Claw 422 ... Convex part 423 ... Convex part 2571 ... Side face 2572 ... Side face 2581 ... Side face 2582 ... Side face 4221 ... Side face 4221 ... Side face 4232 ... Side face

Claims (9)

An outer cylinder that has a liquid storage space inside, has a first hole that extends in the direction of the central axis at a position shifted from the central axis at the tip, and communicates with the liquid storage space;
A seal cap that is provided at the distal end of the outer cylinder so as to be rotatable around a central axis of the outer cylinder, and seals the first hole;
A needle hub attached to the seal cap;
A needle tube supported at the tip of the needle hub,
The seal cap has a second hole that extends in the direction of the central axis of the outer cylinder and communicates with the needle tube at a position shifted from the central axis of the outer cylinder at the tip of the seal cap. ,
When the seal cap is located at the first position, the first hole and the second hole do not communicate with each other, and the first hole is sealed by the seal cap;
When the seal cap rotates from the first position and is located at the second position, the first hole and the second hole communicate with each other, and the first hole and the second hole are in communication with each other. A liquid injection device, wherein the liquid storage space and the needle tube communicate with each other through two holes.   2. A lock cap that sandwiches a part of the seal cap and a part of the outer cylinder from a central axis direction of the outer cylinder and prevents the seal cap from being detached from a front end portion of the outer cylinder. A liquid injection device according to claim 1.   A portion of the needle hub, a portion of the seal cap, and a portion of the outer cylinder are positioned between a portion of the needle hub and a portion of the outer cylinder. The liquid injection device according to claim 1, further comprising a lock cap that is sandwiched from a central axis direction of the outer cylinder and prevents the needle hub and the seal cap from being detached from a distal end portion of the outer cylinder. The lock cap is provided so as to be rotatable around a central axis of the outer cylinder,
The seal cap and the lock cap have a first engagement portion and a second engagement portion that are engaged in a circumferential direction of the outer cylinder,
The liquid injection device according to claim 2 or 3, wherein the seal cap is rotated by rotating the lock cap. A protector that is rotatably provided around the central axis of the outer cylinder and covers the needle tube;
The lock cap and the protector have a third engagement portion and a fourth engagement portion that are engaged in a circumferential direction of the outer cylinder,
The liquid injection device according to claim 4, wherein the lock cap is rotated by rotating the protector.   The liquid injection device according to any one of claims 1 to 5, further comprising a restricting portion that restricts a distal end portion of the seal cap from spreading in a radial direction of the outer cylinder.   The liquid injection device according to any one of claims 1 to 6, wherein the seal cap has a concave portion at a distal end surface. The outer cylinder has a cylindrical body,
The other member is arrange | positioned in the same position as the outer periphery of the said trunk | drum inside or the outer periphery of the said trunk | drum seeing from the center axis direction of the said outer cylinder. Liquid injection device.   The liquid injection device according to any one of claims 1 to 8, wherein the liquid injection device is a prefilled syringe.

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