JP2016540051A5 - - Google Patents
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- JP2016540051A5 JP2016540051A5 JP2016556693A JP2016556693A JP2016540051A5 JP 2016540051 A5 JP2016540051 A5 JP 2016540051A5 JP 2016556693 A JP2016556693 A JP 2016556693A JP 2016556693 A JP2016556693 A JP 2016556693A JP 2016540051 A5 JP2016540051 A5 JP 2016540051A5
- Authority
- JP
- Japan
- Prior art keywords
- ring
- alkyl
- compound according
- group
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C[C@@](*)c1cc(*)ccc1C(N)=* Chemical compound C[C@@](*)c1cc(*)ccc1C(N)=* 0.000 description 13
- SGCNOJRXWAOWPL-UHFFFAOYSA-N CC(C)(C)c(ccc(C)c1)c1F Chemical compound CC(C)(C)c(ccc(C)c1)c1F SGCNOJRXWAOWPL-UHFFFAOYSA-N 0.000 description 2
- OGVXDHCMSPOEMS-UHFFFAOYSA-N CC(C)(C)c(c(F)c1)ccc1S(Nc(cc(c(O1)c2)OC1(F)F)c2-c1ccc(C(O)=O)c2c1cccn2)=O Chemical compound CC(C)(C)c(c(F)c1)ccc1S(Nc(cc(c(O1)c2)OC1(F)F)c2-c1ccc(C(O)=O)c2c1cccn2)=O OGVXDHCMSPOEMS-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361910838P | 2013-12-02 | 2013-12-02 | |
| US61/910,838 | 2013-12-02 | ||
| PCT/US2014/068152 WO2015084842A1 (en) | 2013-12-02 | 2014-12-02 | Ccr6 compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016540051A JP2016540051A (ja) | 2016-12-22 |
| JP2016540051A5 true JP2016540051A5 (https=) | 2018-01-18 |
| JP6563947B2 JP6563947B2 (ja) | 2019-08-21 |
Family
ID=53274030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016556693A Active JP6563947B2 (ja) | 2013-12-02 | 2014-12-02 | Ｃｃｒ６化合物 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US9340509B2 (https=) |
| EP (1) | EP3076968B1 (https=) |
| JP (1) | JP6563947B2 (https=) |
| KR (1) | KR102331833B1 (https=) |
| CN (1) | CN105960237B (https=) |
| AU (1) | AU2014360743C1 (https=) |
| CA (1) | CA2930148C (https=) |
| EA (1) | EA029826B1 (https=) |
| ES (1) | ES2735360T3 (https=) |
| IL (1) | IL245704B (https=) |
| MX (1) | MX2016007128A (https=) |
| WO (1) | WO2015084842A1 (https=) |
| ZA (1) | ZA201603167B (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3076968B1 (en) | 2013-12-02 | 2019-04-17 | ChemoCentryx, Inc. | Ccr6 compounds |
| KR20200037857A (ko) | 2017-08-14 | 2020-04-09 | 알러간, 인코포레이티드 | 3,4-이치환된 3-시클로부텐-1,2-디온 및 그의 용도 |
| BR112020018094A2 (pt) | 2018-03-08 | 2020-12-22 | Incyte Corporation | Compostos de aminopirazina diol como inibidores de pi3k-¿ |
| US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
| KR102880470B1 (ko) | 2018-10-23 | 2025-11-03 | 다이이찌 산쿄 가부시키가이샤 | 바이아릴 유도체 |
| CN117018202A (zh) * | 2019-07-08 | 2023-11-10 | 上海交通大学医学院附属瑞金医院 | 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用 |
| BR112021025888A2 (pt) | 2019-07-10 | 2022-04-26 | Chemocentryx Inc | Indanos como inibidores de pd-l1 |
| JP7736678B2 (ja) | 2019-10-16 | 2025-09-09 | ケモセントリックス，インコーポレイティド | Ｐｄ－ｌ１疾患の処置のためのヘテロアリール－ビフェニルアミド |
| ES3064674T3 (en) | 2019-10-16 | 2026-04-28 | Chemocentryx Inc | Heteroaryl-biphenyl amines for the treatment of pd-l1 diseases |
| AU2021266148A1 (en) | 2020-04-30 | 2023-01-05 | Idorsia Pharmaceuticals Ltd | Azetidin-3-ylmethanol derivatives as CCR6 receptor modulators |
| AU2022328634A1 (en) | 2021-08-18 | 2024-02-22 | Chemocentryx, Inc. | Aryl sulfonyl compounds as ccr6 inhibitors |
| WO2023023532A2 (en) | 2021-08-18 | 2023-02-23 | Chemocentryx, Inc. | Aryl sulfonyl (hydroxy) piperidines as ccr6 inhibitors |
| WO2023057548A1 (en) | 2021-10-07 | 2023-04-13 | Idorsia Pharmaceuticals Ltd | Ccr6 receptor modulators |
| WO2023072924A1 (en) | 2021-10-26 | 2023-05-04 | Idorsia Pharmaceuticals Ltd | Ccr6 receptor modulators |
| TW202325271A (zh) | 2021-10-28 | 2023-07-01 | 瑞士商愛杜西亞製藥有限公司 | Ccr6受體調節劑 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3944553A (en) | 1974-02-13 | 1976-03-16 | Trw Inc. | Bis quinoline peri acids |
| US4021409A (en) | 1975-06-19 | 1977-05-03 | The United States Of America As Represented By The Secretary Of The Air Force | Thermally stable benzimidazonaphthyridine compositions |
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| LU86084A1 (fr) | 1985-09-20 | 1987-04-02 | Faco Sa | Apparei de massage electrique |
| US5102417A (en) | 1985-11-07 | 1992-04-07 | Expandable Grafts Partnership | Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft |
| US4800882A (en) | 1987-03-13 | 1989-01-31 | Cook Incorporated | Endovascular stent and delivery system |
| US4886062A (en) | 1987-10-19 | 1989-12-12 | Medtronic, Inc. | Intravascular radially expandable stent and method of implant |
| WO1990013332A1 (en) | 1989-05-11 | 1990-11-15 | Cedars-Sinai Medical Center | Stent with sustained drug delivery |
| DE69110787T2 (de) | 1990-02-28 | 1996-04-04 | Medtronic, Inc., Minneapolis, Minn. | Intraluminale prothese mit wirkstoffeluierung. |
| US5429634A (en) | 1993-09-09 | 1995-07-04 | Pdt Systems | Biogenic implant for drug delivery and method |
| US5419760A (en) | 1993-01-08 | 1995-05-30 | Pdt Systems, Inc. | Medicament dispensing stent for prevention of restenosis of a blood vessel |
| US6774278B1 (en) | 1995-06-07 | 2004-08-10 | Cook Incorporated | Coated implantable medical device |
| US5833651A (en) | 1996-11-08 | 1998-11-10 | Medtronic, Inc. | Therapeutic intraluminal stents |
| US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6770729B2 (en) | 2002-09-30 | 2004-08-03 | Medtronic Minimed, Inc. | Polymer compositions containing bioactive agents and methods for their use |
| AU2005245401A1 (en) * | 2004-05-12 | 2005-12-01 | Chemocentryx | Aryl sulfonamides |
| DK1838674T3 (da) * | 2005-01-14 | 2011-06-14 | Chemocentryx Inc | Heteroarylsulfonamider og CCR2 |
| WO2008010934A2 (en) * | 2006-07-14 | 2008-01-24 | Chemocentryx, Inc. | Triazolyl phenyl benzenesulfonamides |
| CN101511800B (zh) | 2006-07-14 | 2013-02-27 | 坎莫森特里克斯公司 | 三唑基苯基苯磺酰胺 |
| WO2009008552A1 (en) | 2007-07-11 | 2009-01-15 | Taisho Pharmaceutical Co., Ltd. | 8-aryl-4-alkylpyrrolo[2,3,4-de]quinolin-5(4h)-one and 8-aryl-4-alkyl-4,5-dihydropyrrolo[2,3,4-de]quinolin-5-ol derivatives |
| JP5306344B2 (ja) * | 2007-07-12 | 2013-10-02 | ケモセントリックス， インコーポレイテッド | 炎症の治療のためのｃｃｒ２モジュレーターとしての縮合ヘテロアリールピリジルおよびフェニルベンゼンスルホンアミド |
| AR070513A1 (es) * | 2007-08-01 | 2010-04-14 | Lundbeck & Co As H | Uso de abridores de canales de potasio kcnq para reducir los sintomas o tratar desordenes o afecciones en las cuales se encuentra anulado el sis-tema dopaminergico como por ejemplo esquizofrenia y trastorno depresivo mayor |
| ES2554513T3 (es) | 2008-05-23 | 2015-12-21 | Novartis Ag | Derivados de quinolinas y quinoxalinas como inhibidores de la proteína tirosina quinasa |
| CA2725014C (en) * | 2008-05-30 | 2014-06-17 | Amgen Inc. | Inhibitors of pi3 kinase |
| US8546405B2 (en) | 2008-12-23 | 2013-10-01 | Abbott Laboratories | Anti-viral compounds |
| JP2013504325A (ja) | 2009-09-09 | 2013-02-07 | アビラ セラピューティクス， インコーポレイテッド | Ｐｉ３キナーゼインヒビターおよびその使用 |
| TWI487486B (zh) | 2009-12-01 | 2015-06-11 | Syngenta Participations Ag | 以異唑啉衍生物為主之殺蟲化合物 |
| US9284301B2 (en) * | 2010-03-25 | 2016-03-15 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase activators |
| CN103347520A (zh) | 2010-10-13 | 2013-10-09 | 波士顿大学管理委员会 | 用作癌症化学治疗的晚期sv40因子（lsf）的抑制剂 |
| KR101985184B1 (ko) | 2011-01-28 | 2019-06-03 | 주식회사 동진쎄미켐 | 신규한 유기염료 및 이의 제조방법 |
| TW201311149A (zh) | 2011-06-24 | 2013-03-16 | Ishihara Sangyo Kaisha | 有害生物防治劑 |
| US9307766B2 (en) | 2011-08-25 | 2016-04-12 | Syngenta Participations Ag | Isoxazoline derivatives as insecticidal compounds |
| FR2981935B1 (fr) * | 2011-10-28 | 2015-08-07 | Galderma Res & Dev | Nouveaux composes di-substitues de la diamino-3,4-cyclobutene-3-dione-1,2 utiles dans le traitement de pathologies mediees par des chimiokines. |
| FR2981934B1 (fr) | 2011-10-28 | 2013-12-20 | Galderma Res & Dev | Nouveaux composes di-substitues de la diamino-3,4-cyclobutene-3-dione-1,2 utiles dans le traitement de pathologies mediees par des chimiokines. |
| RU2627268C2 (ru) * | 2012-02-29 | 2017-08-04 | Хемоцентрикс, Инк. | Аза-арил-1Н-пиразол-1-ил-сульфонамиды |
| EP3076968B1 (en) | 2013-12-02 | 2019-04-17 | ChemoCentryx, Inc. | Ccr6 compounds |
-
2014
- 2014-12-02 EP EP14867718.0A patent/EP3076968B1/en active Active
- 2014-12-02 CN CN201480065637.7A patent/CN105960237B/zh active Active
- 2014-12-02 KR KR1020167017459A patent/KR102331833B1/ko active Active
- 2014-12-02 ES ES14867718T patent/ES2735360T3/es active Active
- 2014-12-02 AU AU2014360743A patent/AU2014360743C1/en active Active
- 2014-12-02 EA EA201691141A patent/EA029826B1/ru not_active IP Right Cessation
- 2014-12-02 US US14/557,949 patent/US9340509B2/en active Active
- 2014-12-02 CA CA2930148A patent/CA2930148C/en active Active
- 2014-12-02 JP JP2016556693A patent/JP6563947B2/ja active Active
- 2014-12-02 MX MX2016007128A patent/MX2016007128A/es active IP Right Grant
- 2014-12-02 WO PCT/US2014/068152 patent/WO2015084842A1/en not_active Ceased
-
2016
- 2016-03-18 US US15/074,965 patent/US9795599B2/en active Active
- 2016-05-11 ZA ZA2016/03167A patent/ZA201603167B/en unknown
- 2016-05-18 IL IL24570416A patent/IL245704B/en active IP Right Grant
-
2017
- 2017-09-19 US US15/709,012 patent/US10117865B2/en active Active
-
2018
- 2018-10-03 US US16/150,796 patent/US10786494B2/en active Active
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