JP2016536990A5 - - Google Patents

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JP2016536990A5
JP2016536990A5 JP2016529958A JP2016529958A JP2016536990A5 JP 2016536990 A5 JP2016536990 A5 JP 2016536990A5 JP 2016529958 A JP2016529958 A JP 2016529958A JP 2016529958 A JP2016529958 A JP 2016529958A JP 2016536990 A5 JP2016536990 A5 JP 2016536990A5
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Japan
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compound
polypeptide
seq
sequence
amino acid
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JP2016529958A
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JP6643987B2 (ja
JP2016536990A (ja
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Priority claimed from PCT/US2014/065259 external-priority patent/WO2015073555A1/en
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JP2016529958A 2013-11-13 2014-11-12 ケトン化合物およびアミン化合物の還元的アミノ化のための操作されたイミンレダクターゼおよび方法 Active JP6643987B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361903772P 2013-11-13 2013-11-13
US61/903,772 2013-11-13
US201462022315P 2014-07-09 2014-07-09
US201462022323P 2014-07-09 2014-07-09
US62/022,323 2014-07-09
US62/022,315 2014-07-09
PCT/US2014/065259 WO2015073555A1 (en) 2013-11-13 2014-11-12 Engineered imine reductases and methods for the reductive amination of ketone and amine compounds

Publications (3)

Publication Number Publication Date
JP2016536990A JP2016536990A (ja) 2016-12-01
JP2016536990A5 true JP2016536990A5 (enExample) 2019-04-11
JP6643987B2 JP6643987B2 (ja) 2020-02-12

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JP2016529958A Active JP6643987B2 (ja) 2013-11-13 2014-11-12 ケトン化合物およびアミン化合物の還元的アミノ化のための操作されたイミンレダクターゼおよび方法

Country Status (9)

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US (5) US9822346B2 (enExample)
EP (1) EP3068793B1 (enExample)
JP (1) JP6643987B2 (enExample)
CN (1) CN106232619B (enExample)
CA (1) CA2929664C (enExample)
DK (1) DK3068793T3 (enExample)
HU (1) HUE053379T2 (enExample)
IL (1) IL245453B (enExample)
WO (1) WO2015073555A1 (enExample)

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KR101761830B1 (ko) 2015-10-21 2017-07-26 주식회사 엘지화학 리간드 화합물, 올레핀 올리고머화용 촉매계, 및 이를 이용한 올레핀 올리고머화 방법
WO2018038906A1 (en) 2016-08-26 2018-03-01 Codexis, Inc. Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
CN107384885B (zh) * 2017-09-05 2019-12-24 武汉大学 亚胺还原酶及其突变体在合成(s)-1-芳基-1,2,3,4-四氢异喹啉中的应用
CN108504701B (zh) * 2018-04-26 2021-05-14 中南林业科技大学 一种异丙甲草胺中间体的合成方法
HUE051799T2 (hu) 2018-11-16 2021-03-29 Zanoprima Lifesciences Ltd Eljárás (S)-nikotin elõállítására myosmine vegyületbõl
EP3963057A4 (en) * 2019-05-01 2023-06-14 Codexis, Inc. MANIPULATED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS
CN116286700B (zh) * 2021-10-18 2025-10-03 迪嘉药业集团股份有限公司 一种亚胺还原酶突变体及用途
CN114717211B (zh) * 2022-03-23 2023-06-02 江苏集萃分子工程研究院有限公司 亚胺还原酶突变体m5及其在合成氮杂环手性胺中的应用
CN116814569B (zh) * 2023-05-30 2025-07-25 华东理工大学 一种催化活性提高的醇脱氢酶突变体、基因工程菌及其应用
CN119931979B (zh) * 2024-11-27 2026-06-23 南京药石科技股份有限公司 一种亚胺还原酶突变体及其应用

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