JP2016535746A5 - - Google Patents

Info

Publication number

JP2016535746A5

JP2016535746A5 JP2016526896A JP2016526896A JP2016535746A5 JP 2016535746 A5 JP2016535746 A5 JP 2016535746A5 JP 2016526896 A JP2016526896 A JP 2016526896A JP 2016526896 A JP2016526896 A JP 2016526896A JP 2016535746 A5 JP2016535746 A5 JP 2016535746A5

Authority

JP

Japan

Prior art keywords

extract

hydroxyadenosine

adenine

uridine

juice

Prior art date

2014-10-28

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

• Espacenet
• Global Dossier
• Discuss

• DRTQHJPVMGBUCF-XVFCMESISA-N Uridine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-XVFCMESISA-N 0.000 claims 14
• 235000011389 fruit/vegetable juice Nutrition 0.000 claims 8
• GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 claims 7
• 229930024421 Adenine Natural products 0.000 claims 7
• MIKUYHXYGGJMLM-UUOKFMHZSA-N Crotonoside Chemical compound C1=NC2=C(N)NC(=O)N=C2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O MIKUYHXYGGJMLM-UUOKFMHZSA-N 0.000 claims 7
• MIKUYHXYGGJMLM-GIMIYPNGSA-N Crotonoside Natural products C1=NC2=C(N)NC(=O)N=C2N1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O MIKUYHXYGGJMLM-GIMIYPNGSA-N 0.000 claims 7
• 229960000643 adenine Drugs 0.000 claims 7
• DRTQHJPVMGBUCF-PSQAKQOGSA-N beta-L-uridine Natural products O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-PSQAKQOGSA-N 0.000 claims 7
• 239000000203 mixture Substances 0.000 claims 7
• DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 claims 7
• 229940045145 uridine Drugs 0.000 claims 7
• 235000009811 Momordica charantia Nutrition 0.000 claims 5
• 244000078912 Trichosanthes cucumerina Species 0.000 claims 5
• 235000008322 Trichosanthes cucumerina Nutrition 0.000 claims 5
• 230000000975 bioactive effect Effects 0.000 claims 5
• CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 4
• 206010012601 diabetes mellitus Diseases 0.000 claims 3
• 238000004519 manufacturing process Methods 0.000 claims 3
• 239000003550 marker Substances 0.000 claims 3
• 208000030159 metabolic disease Diseases 0.000 claims 3
• -1 nitrogen-containing heterocyclic compound Chemical class 0.000 claims 3
• ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims 2
• FSVCELGFZIQNCK-UHFFFAOYSA-N N,N-bis(2-hydroxyethyl)glycine Chemical compound OCCN(CCO)CC(O)=O FSVCELGFZIQNCK-UHFFFAOYSA-N 0.000 claims 2
• 229930003268 Vitamin C Natural products 0.000 claims 2
• 239000007998 bicine buffer Substances 0.000 claims 2
• 239000003814 drug Substances 0.000 claims 2
• 239000000835 fiber Substances 0.000 claims 2
• 239000000546 pharmaceutical excipient Substances 0.000 claims 2
• 235000019154 vitamin C Nutrition 0.000 claims 2
• 239000011718 vitamin C Substances 0.000 claims 2
• 241001131796 Botaurus stellaris Species 0.000 claims 1
• 230000002378 acidificating effect Effects 0.000 claims 1
• 239000003513 alkali Substances 0.000 claims 1
• 239000002585 base Substances 0.000 claims 1
• 238000004821 distillation Methods 0.000 claims 1
• 238000001035 drying Methods 0.000 claims 1
• 235000013399 edible fruits Nutrition 0.000 claims 1
• 238000001914 filtration Methods 0.000 claims 1
• 239000008240 homogeneous mixture Substances 0.000 claims 1
• 238000000034 method Methods 0.000 claims 1
• 239000002245 particle Substances 0.000 claims 1
• 239000007787 solid Substances 0.000 claims 1
• 230000001256 tonic effect Effects 0.000 claims 1
• 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1