JP2016535009A - 抗体依存性エキソソーム治療の方法 - Google Patents
抗体依存性エキソソーム治療の方法 Download PDFInfo
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- JP2016535009A JP2016535009A JP2016524060A JP2016524060A JP2016535009A JP 2016535009 A JP2016535009 A JP 2016535009A JP 2016524060 A JP2016524060 A JP 2016524060A JP 2016524060 A JP2016524060 A JP 2016524060A JP 2016535009 A JP2016535009 A JP 2016535009A
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- cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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- C—CHEMISTRY; METALLURGY
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- C—CHEMISTRY; METALLURGY
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- C07K2317/622—Single chain antibody (scFv)
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- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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- Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Developmental Biology & Embryology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361892352P | 2013-10-17 | 2013-10-17 | |
| US61/892,352 | 2013-10-17 | ||
| US201462038734P | 2014-08-18 | 2014-08-18 | |
| US62/038,734 | 2014-08-18 | ||
| PCT/US2014/061245 WO2015058148A1 (en) | 2013-10-17 | 2014-10-17 | Antibody dependent exosome therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016535009A true JP2016535009A (ja) | 2016-11-10 |
| JP2016535009A5 JP2016535009A5 (enExample) | 2017-11-09 |
Family
ID=52828772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016524060A Pending JP2016535009A (ja) | 2013-10-17 | 2014-10-17 | 抗体依存性エキソソーム治療の方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20160243192A1 (enExample) |
| EP (1) | EP3057662A4 (enExample) |
| JP (1) | JP2016535009A (enExample) |
| WO (1) | WO2015058148A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023536665A (ja) * | 2020-08-05 | 2023-08-28 | オハイオ・ステイト・イノベーション・ファウンデーション | アダプターポリペプチドおよびその使用方法 |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120315324A1 (en) | 2010-02-05 | 2012-12-13 | University Of Louisville Research Foundation, Inc. | Exosomal compositions and methods for the treatment of disease |
| US20140308212A1 (en) | 2011-11-07 | 2014-10-16 | University Of Louisville Research Foundation, Inc. | Edible plant-derived microvesicle compositions for diagnosis and treatment of disease |
| WO2015157652A1 (en) | 2014-04-11 | 2015-10-15 | University Of Louisville Research Foundation, Inc. | Coated edible plant-derived microvesicle compositions and methods for using the same |
| WO2017004526A1 (en) * | 2015-07-02 | 2017-01-05 | University Of Louisville Research Foundation, Inc. | EDIBLE PLANT-DERIVED MICROVESICLE COMPOSITIONS FOR DELIVERY OF miRNA AND METHODS FOR TREATMENT OF CANCER |
| NZ759528A (en) | 2015-11-18 | 2025-07-25 | Univ Georgia | Neural cell extracellular vessicles |
| WO2017087685A1 (en) | 2015-11-20 | 2017-05-26 | The Regents Of The University Of California | Deformable nano-scale vehicles (dnvs) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery |
| GB2552473A (en) * | 2016-07-21 | 2018-01-31 | Evox Therapeutics Ltd | Surface decoration of extracellular vesicles |
| US10815520B2 (en) | 2017-04-07 | 2020-10-27 | University Of Louisville Research Foundation, Inc. | Nanovesicles, methods, and systems for diagnosis and prognosis of cancer |
| EP3438250B1 (en) * | 2017-07-31 | 2022-12-07 | Rheinische Friedrich-Wilhelms-Universität Bonn | Cell derived extracellular vesicles for the treatment of diseases |
| US12036262B2 (en) | 2017-11-22 | 2024-07-16 | University Of Louisville Research Foundation, Inc. | Edible plant-derived nanoparticles for regulation of gut microbiota |
| CN107998149B (zh) * | 2017-12-11 | 2020-05-19 | 浙江大学 | NK细胞外泌体及相关miRNA在抗菌和抗肿瘤中的应用 |
| CA3088009A1 (en) * | 2018-02-12 | 2019-08-15 | Codiak Biosciences, Inc. | Methods and compositions for macrophage polarization |
| IL266153A (en) * | 2019-04-18 | 2019-07-31 | Aharon Anat | Extracellular vesicles derived from t cells containing a chimeric antigen receptor |
| JP7479399B2 (ja) | 2019-05-06 | 2024-05-08 | マルコム,トーマス | 癌腫瘍に対するテーラード低免疫ナノ小胞送達系 |
| US11607428B2 (en) | 2019-06-06 | 2023-03-21 | Spiritus Therapeutics, Inc. | Mesenchymal stem cell-derived extracellular vesicles and uses thereof for treating and diagnosing fibrotic diseases |
| US12097222B2 (en) | 2019-06-06 | 2024-09-24 | Spiritus Therapeutics, Inc. | Methods for attenuating viral infection and for treating lung injury |
| WO2020247675A1 (en) * | 2019-06-06 | 2020-12-10 | Spiritus Therapeutics, Inc. | Methods for attenuating viral infection and for treating lung injury |
| US20210130782A1 (en) * | 2019-10-28 | 2021-05-06 | Augusta University Research Institute, Inc. | Engineered Exosomes to Detect and Deplete Pro-Tumorigenic Macrophages |
| CN115942957A (zh) * | 2019-11-04 | 2023-04-07 | 阿鲁纳生物股份公司 | 细胞外囊泡及其用于抗体递送的用途 |
| CN111450249A (zh) * | 2020-03-09 | 2020-07-28 | 杨静悦 | miRNA-320a的表达促进物在制备抑制肿瘤细胞药物中的应用 |
| WO2022149779A1 (ko) * | 2021-01-11 | 2022-07-14 | 주식회사 엑소코바이오 | 과발현된 Fc 수용체 또는 이의 일부를 포함하는 엑소좀 및 이의 제조방법 |
| WO2022158836A1 (ko) * | 2021-01-21 | 2022-07-28 | 주식회사 엑소코바이오 | 목적 단백질 또는 펩타이드가 융합가능한 Fc 수용체 또는 이의 일부를 포함하는 재조합 엑소좀 및 이의 용도 |
| WO2023081109A1 (en) * | 2021-11-05 | 2023-05-11 | Malcolm Thomas | Tailored hypoimmune nanovesicular delivery systems for cancer tumors, hereditary and infectious diseases |
| CN115887491A (zh) * | 2022-11-10 | 2023-04-04 | 中国药科大学 | 一种具有骨髓靶向功能的工程化双特异性外泌体/囊泡制剂及其制备方法和应用 |
| WO2024196812A1 (en) * | 2023-03-20 | 2024-09-26 | MAM Holdings of West Florida, L.L.C. | Mesenchymal stem cell-derived micro-ribonucleic acid-mediated treatments for the prevention and targeted treatment of cancer and other disorders |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100590131C (zh) * | 2001-08-17 | 2010-02-17 | 埃克索泰拉有限公司 | 用于将蛋白定向到胞外体的方法和化合物 |
| CA2516028C (en) * | 2003-02-14 | 2012-10-16 | University Of Southern California | Conjugates comprising a cancer targeting molecule linked to a liver-expressed chemokine |
| IL161899A0 (en) * | 2004-05-10 | 2005-11-20 | Hoffman Arnold | Kit for treatment of cancer |
| MX363905B (es) * | 2006-06-12 | 2019-04-08 | Aptevo Res & Development Llc | Proteinas de union multivalentes monocatenarias con funcion efectora. |
| US20120315324A1 (en) * | 2010-02-05 | 2012-12-13 | University Of Louisville Research Foundation, Inc. | Exosomal compositions and methods for the treatment of disease |
-
2014
- 2014-10-17 EP EP14854517.1A patent/EP3057662A4/en not_active Withdrawn
- 2014-10-17 JP JP2016524060A patent/JP2016535009A/ja active Pending
- 2014-10-17 WO PCT/US2014/061245 patent/WO2015058148A1/en not_active Ceased
- 2014-10-17 US US15/029,395 patent/US20160243192A1/en not_active Abandoned
Non-Patent Citations (3)
| Title |
|---|
| CLIN. CANCER RES, vol. 19, no. 8, JPN6018021559, 15 April 2013 (2013-04-15), pages 2132 - 2143, ISSN: 0003965760 * |
| ONCOIMMUNOLOGY, vol. 2, no. 1, JPN6018021560, 1 January 2013 (2013-01-01), pages 22337 - 3, ISSN: 0003815160 * |
| THE JOURNAL OF IMMUNOLOGY, vol. 189, JPN6018021558, 2012, pages 2833 - 2842, ISSN: 0003965759 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023536665A (ja) * | 2020-08-05 | 2023-08-28 | オハイオ・ステイト・イノベーション・ファウンデーション | アダプターポリペプチドおよびその使用方法 |
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| Publication number | Publication date |
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| EP3057662A1 (en) | 2016-08-24 |
| US20160243192A1 (en) | 2016-08-25 |
| EP3057662A4 (en) | 2017-03-29 |
| WO2015058148A1 (en) | 2015-04-23 |
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