JP2016532115A - 被験体において心不全を診断するための手段及び方法 - Google Patents

被験体において心不全を診断するための手段及び方法 Download PDF

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Publication number
JP2016532115A
JP2016532115A JP2016537328A JP2016537328A JP2016532115A JP 2016532115 A JP2016532115 A JP 2016532115A JP 2016537328 A JP2016537328 A JP 2016537328A JP 2016537328 A JP2016537328 A JP 2016537328A JP 2016532115 A JP2016532115 A JP 2016532115A
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Prior art keywords
sphingomyelin
cholesteryl ester
biomarkers
group
heart failure
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Ceased
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JP2016537328A
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English (en)
Japanese (ja)
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JP2016532115A5 (cg-RX-API-DMAC10.html
Inventor
ヴィット，ヘニング
カストラー，ユルゲン
ベタン，ビアンカ
ペーター，エリク
シャッツ，フィリップ
ディルク デュンゲン，ハンス
ディルク デュンゲン，ハンス
ダニエル トリッペル，トビアス
ダニエル トリッペル，トビアス
タイロビック，エルヴィス
アー． カトゥス，フューゴ
アー． カトゥス，フューゴ
フライ，ノルベルト
ヴァイス，タンヤ
Original Assignee
メタノミクス ゲーエムベーハー
メタノミクス ゲーエムベーハー
ルプレヒト−カールス−ウニベルジテート ハイデルベルク
ルプレヒト−カールス−ウニベルジテート ハイデルベルク
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Application filed by メタノミクス ゲーエムベーハー, メタノミクス ゲーエムベーハー, ルプレヒト−カールス−ウニベルジテート ハイデルベルク, ルプレヒト−カールス−ウニベルジテート ハイデルベルク filed Critical メタノミクス ゲーエムベーハー
Publication of JP2016532115A publication Critical patent/JP2016532115A/ja
Publication of JP2016532115A5 publication Critical patent/JP2016532115A5/ja
Ceased legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/08—Sphingolipids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Databases & Information Systems (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioethics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Theoretical Computer Science (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2016537328A 2013-08-30 2014-09-01 被験体において心不全を診断するための手段及び方法 Ceased JP2016532115A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13182441.9 2013-08-30
EP13182441 2013-08-30
PCT/EP2014/068530 WO2015028671A1 (en) 2013-08-30 2014-09-01 Means and methods for diagnosing heart failure in a subject

Publications (2)

Publication Number Publication Date
JP2016532115A true JP2016532115A (ja) 2016-10-13
JP2016532115A5 JP2016532115A5 (cg-RX-API-DMAC10.html) 2017-10-12

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JP2016537328A Ceased JP2016532115A (ja) 2013-08-30 2014-09-01 被験体において心不全を診断するための手段及び方法

Country Status (5)

Country Link
US (1) US20160209433A1 (cg-RX-API-DMAC10.html)
EP (1) EP3039430A1 (cg-RX-API-DMAC10.html)
JP (1) JP2016532115A (cg-RX-API-DMAC10.html)
CA (1) CA2922331A1 (cg-RX-API-DMAC10.html)
WO (1) WO2015028671A1 (cg-RX-API-DMAC10.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9285378B2 (en) * 2010-01-29 2016-03-15 Metanomics Gmbh Means and methods for diagnosing heart failure in a subject
JP2017523417A (ja) * 2014-07-28 2017-08-17 メタノミクス ゲーエムベーハー コレステロールパラメータ、スフィンゴミエリンおよび／またはトリアシルグリセロールに基づいて心不全を診断するための手段および方法
WO2016034600A1 (en) * 2014-09-01 2016-03-10 Metanomics Gmbh Means and methods for diagnosing heart failure in a subject
WO2017029401A1 (en) * 2015-08-19 2017-02-23 Metanomics Gmbh Means and methods for diagnosing cardiac disease in a subject
US11275093B2 (en) * 2016-03-09 2022-03-15 Cbmed Gmbh Center For Biomarker Research In Medicine Biomarker for the diagnosis of pulmonary hypertension (PH)
CN115112776B (zh) * 2021-03-18 2023-07-04 中国科学院大连化学物理研究所 联合标志物及在诊断心房颤动中应用及诊断试剂或试剂盒

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006526140A (ja) * 2002-12-24 2006-11-16 バイオサイト インコーポレイテッド 鑑別診断のためのマーカーおよびその使用方法
WO2011092285A2 (en) * 2010-01-29 2011-08-04 Metanomics Gmbh Means and methods for diagnosing heart failure in a subject
WO2013014286A2 (en) * 2011-07-28 2013-01-31 Metanomics Gmbh Means and methods for diagnosing and monitoring heart failure in a subject

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006526140A (ja) * 2002-12-24 2006-11-16 バイオサイト インコーポレイテッド 鑑別診断のためのマーカーおよびその使用方法
WO2011092285A2 (en) * 2010-01-29 2011-08-04 Metanomics Gmbh Means and methods for diagnosing heart failure in a subject
JP2013518271A (ja) * 2010-01-29 2013-05-20 メタノミクス ゲーエムベーハー 被験体において心不全を診断するための手段及び方法
WO2013014286A2 (en) * 2011-07-28 2013-01-31 Metanomics Gmbh Means and methods for diagnosing and monitoring heart failure in a subject

Also Published As

Publication number Publication date
EP3039430A1 (en) 2016-07-06
WO2015028671A1 (en) 2015-03-05
US20160209433A1 (en) 2016-07-21
CA2922331A1 (en) 2015-03-05

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