JP2016531910A5 - - Google Patents

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Publication number
JP2016531910A5
JP2016531910A5 JP2016534873A JP2016534873A JP2016531910A5 JP 2016531910 A5 JP2016531910 A5 JP 2016531910A5 JP 2016534873 A JP2016534873 A JP 2016534873A JP 2016534873 A JP2016534873 A JP 2016534873A JP 2016531910 A5 JP2016531910 A5 JP 2016531910A5
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JP
Japan
Prior art keywords
organ
composition
complement inhibitor
complement
composition according
Prior art date
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Pending
Application number
JP2016534873A
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English (en)
Japanese (ja)
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JP2016531910A (ja
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Priority claimed from PCT/US2014/051323 external-priority patent/WO2015023972A1/en
Publication of JP2016531910A publication Critical patent/JP2016531910A/ja
Publication of JP2016531910A5 publication Critical patent/JP2016531910A5/ja
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JP2016534873A 2013-08-16 2014-08-15 移植前の臓器への補体阻害剤の投与による移植拒絶の処置 Pending JP2016531910A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361867009P 2013-08-16 2013-08-16
US61/867,009 2013-08-16
PCT/US2014/051323 WO2015023972A1 (en) 2013-08-16 2014-08-15 Treatment of graft rejection by administering a complement inhibitor to an organ prior to transplant

Publications (2)

Publication Number Publication Date
JP2016531910A JP2016531910A (ja) 2016-10-13
JP2016531910A5 true JP2016531910A5 (enExample) 2017-09-28

Family

ID=51494495

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016534873A Pending JP2016531910A (ja) 2013-08-16 2014-08-15 移植前の臓器への補体阻害剤の投与による移植拒絶の処置

Country Status (5)

Country Link
US (1) US20160184391A1 (enExample)
EP (1) EP3033093A1 (enExample)
JP (1) JP2016531910A (enExample)
CA (1) CA2920293A1 (enExample)
WO (1) WO2015023972A1 (enExample)

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EP2006381B1 (en) 2006-03-31 2016-02-03 Chugai Seiyaku Kabushiki Kaisha Method for controlling blood pharmacokinetics of antibodies
CA2700701C (en) 2007-09-26 2020-12-29 Chugai Seiyaku Kabushiki Kaisha Method of modifying isoelectric point of antibody via amino acid substitution in cdr
NZ717429A (en) 2008-04-11 2018-07-27 Chugai Pharmaceutical Co Ltd Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
CN108715614A (zh) 2010-11-30 2018-10-30 中外制药株式会社 与多分子的抗原重复结合的抗原结合分子
ES3044832T3 (en) 2011-06-22 2025-11-27 Apellis Pharmaceuticals Inc Methods of treating chronic disorders with complement inhibitors
KR102650420B1 (ko) 2014-12-19 2024-03-21 추가이 세이야쿠 가부시키가이샤 항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
TWI617580B (zh) 2014-12-19 2018-03-11 中外製藥股份有限公司 抗ｃ５抗體及使用方法
US20180311345A1 (en) 2015-10-30 2018-11-01 Alexion Pharmaceuticals, Inc. A method of inhibiting exacerbations of t cell-mediated allograft vasculopathy
TWI747936B (zh) 2015-12-18 2021-12-01 日商中外製藥股份有限公司 抗ｃ５抗體及使用方法
CN109310759A (zh) * 2016-06-07 2019-02-05 诺华股份有限公司 用于在移植排斥治疗中使用的特斯多鲁单抗
RU2018146778A (ru) * 2016-06-07 2020-07-09 Новартис Аг Режим дозирования антитела к c5
TW202300168A (zh) 2016-08-05 2023-01-01 日商中外製藥股份有限公司 Il-8相關疾病之治療用或預防用組成物
WO2018075462A1 (en) * 2016-10-17 2018-04-26 Medical University Of South Carolina Compositions and methods for treating and preventing transplant-associated injury
GB201709222D0 (en) * 2017-06-09 2017-07-26 Univ Manchester C3b Inactivating Polypeptide
GB201800620D0 (en) 2018-01-15 2018-02-28 Univ Manchester C3b Binding Polypeptide
JP7570316B2 (ja) * 2018-08-17 2024-10-21 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア 糖鎖抗原除去のための酵素組成物、それに関連する方法、使用、装置およびシステム
US20220009979A1 (en) * 2018-08-22 2022-01-13 Alexion Pharmaceuticals, Inc. Fusion proteins and methods of treating complement dysregulation using the same
AU2020241879A1 (en) * 2019-03-21 2021-11-04 The Uab Research Foundation Method for increasing cell susceptibility to complement-mediated lysis
WO2020210480A2 (en) * 2019-04-10 2020-10-15 University Of Massachusetts Factor h vectors and uses thereof
CN110423271A (zh) * 2019-08-07 2019-11-08 北京市农林科学院 鸡cr2基因的克隆、蛋白的表达和纯化及其多克隆抗体的制备
CA3182800A1 (en) 2020-06-14 2021-12-23 Vertex Pharmaceuticals Inc. Complement factor i-related compositions and methods
WO2022251168A1 (en) * 2021-05-25 2022-12-01 Alexion Pharmaceuticals, Inc. Kidney active fusion proteins and methods of treatment using the same

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US5723282A (en) 1991-07-08 1998-03-03 The American National Red Cross Method of preparing organs for vitrification
US6074642A (en) 1994-05-02 2000-06-13 Alexion Pharmaceuticals, Inc. Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
WO1995031897A1 (en) 1994-05-20 1995-11-30 Vec Tec, Inc. Method and apparatus monitoring viability of transplantable organs
US6214966B1 (en) 1996-09-26 2001-04-10 Shearwater Corporation Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
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AU1521000A (en) 1998-11-06 2000-05-29 Schepens Eye Research Institute, Inc., The Local use of soluble tumor necrosis receptor i (stnfri) for prophylaxis and treatment of corneal transplant rejection and other disorders of the eye
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US6820011B2 (en) 2001-04-11 2004-11-16 The Regents Of The University Of Colorado Three-dimensional structure of complement receptor type 2 and uses thereof
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JP2007527299A (ja) * 2004-03-05 2007-09-27 グローバル アプライアンス テクノロジーズ インコーポレイテッド コンベヤオーブン
PT1755674E (pt) 2004-05-14 2015-02-05 Alexion Pharma Inc Prolongamento da sobrevivência de um aloenxerto por inibição da atividade do complemento
EP2377951A1 (en) 2005-02-14 2011-10-19 University of Iowa Research Foundation Methods and reagents for treatment and diagnosis of age-related macular degeneration
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BRPI0712987A2 (pt) * 2006-06-21 2012-04-10 Musc Found For Res Dev tratamento de doenças direcionado ao fator h do complemento
AU2009313203B2 (en) * 2008-11-10 2015-08-27 Alexion Pharmaceuticals, Inc. Methods and compositions for treating complement-associated disorders
US20130323708A1 (en) 2009-07-01 2013-12-05 Massachusetts Institute Of Technology Isolated adult cells, artificial organs, rehabilitated organs, research tools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same

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