JP2016529306A5 - - Google Patents
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- Publication number
- JP2016529306A5 JP2016529306A5 JP2016539571A JP2016539571A JP2016529306A5 JP 2016529306 A5 JP2016529306 A5 JP 2016529306A5 JP 2016539571 A JP2016539571 A JP 2016539571A JP 2016539571 A JP2016539571 A JP 2016539571A JP 2016529306 A5 JP2016529306 A5 JP 2016529306A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cyano
- hydroxyl
- disease
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13183519.1 | 2013-09-09 | ||
| EP13183519 | 2013-09-09 | ||
| EP14151979.3 | 2014-01-21 | ||
| EP14151979 | 2014-01-21 | ||
| PCT/EP2014/069088 WO2015032945A1 (en) | 2013-09-09 | 2014-09-08 | Peptidyl nitril compounds as dipeptidyl peptidase i inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016529306A JP2016529306A (ja) | 2016-09-23 |
| JP2016529306A5 true JP2016529306A5 (OSRAM) | 2017-10-12 |
| JP6408008B2 JP6408008B2 (ja) | 2018-10-17 |
Family
ID=51535425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016539571A Active JP6408008B2 (ja) | 2013-09-09 | 2014-09-08 | ジペプチジルペプチダーゼｉインヒビターとしてのペプチジルニトリル化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9856228B2 (OSRAM) |
| EP (1) | EP3044214B1 (OSRAM) |
| JP (1) | JP6408008B2 (OSRAM) |
| CN (1) | CN105612149A (OSRAM) |
| AU (1) | AU2014317048B2 (OSRAM) |
| CA (1) | CA2923484C (OSRAM) |
| DK (1) | DK3044214T3 (OSRAM) |
| EA (1) | EA029030B1 (OSRAM) |
| SG (1) | SG11201601150WA (OSRAM) |
| WO (2) | WO2015032943A1 (OSRAM) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015032943A1 (en) | 2013-09-09 | 2015-03-12 | Prozymex A/S | Peptidyl nitril compounds as dipeptidyl peptidase i inhibitors |
| NO2699580T3 (OSRAM) | 2014-01-24 | 2018-02-24 | ||
| CA2978234C (en) | 2015-03-05 | 2023-05-02 | Prozymex A/S | Peptidyl nitril compounds as dipeptidyl peptidase i inhibitors |
| PL3280401T3 (pl) | 2015-04-07 | 2022-02-14 | Ela Pharma Ltd | Kompozycje do leczenia i/lub zapobiegania martwicy komórek lub tkanek specjalnie ukierunkowane na katepsynę C i/lub CELA1 i/lub CELA3A i/lub strukturalnie związane z nimi enzymy |
| FI3758708T3 (fi) | 2018-03-01 | 2025-02-18 | Astrazeneca Ab | (2s)-{(1s)-1-syano-2-[4-(3-metyyli-2-okso-2,3-dihydro-1,3-bentsoksatsol-5-yyli)fenyyli]etyyli}-1,4-oksatsepaani-2-karboksamidia käsittäviä farmaseuttisia koostumuksia |
| KR20210032431A (ko) | 2018-07-17 | 2021-03-24 | 인스메드 인코포레이티드 | 루푸스 신염을 치료하기 위한 특정 (2s)-n-[(1s)-1-시아노-2-페닐에틸]-1,4-옥사제판-2-카복스아미드 |
| EP4182700A4 (en) | 2020-07-20 | 2024-11-13 | Insmed Incorporated | METHODS FOR EXTRACTING NEUTROPHIL SERINE PROTEASES AND TREATMENT OF DIPETIDYL PEPTIDASE-1-MEDIATED DISEASES |
| AU2023296161A1 (en) | 2022-06-13 | 2025-01-02 | Alivexis, Inc. | Azacycloalkyl carbonyl cyclic amine compound |
| IL321931A (en) | 2023-01-06 | 2025-09-01 | Insmed Inc | New and reversible DPP1 inhibitors and their uses |
| WO2025162472A1 (en) * | 2024-01-31 | 2025-08-07 | Insmed Incorporated | Linear dipeptidyl peptidase 1 inhibitors and uses thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008334444B2 (en) * | 2007-12-12 | 2011-12-15 | Astrazeneca Ab | Peptidyl nitriles and use thereof as dipeptidyl peptidase I inhibitors |
| KR100903499B1 (ko) | 2007-12-27 | 2009-06-18 | 엔에이치엔비즈니스플랫폼 주식회사 | 검색 의도 분류에 따른 광고 제공 방법 및 상기 방법을수행하기 위한 시스템 |
| JP2012526093A (ja) * | 2009-05-07 | 2012-10-25 | アストラゼネカ・アクチエボラーグ | 置換１−シアノエチルヘテロシクリルカルボキサミド化合物７５０ |
| WO2010142985A1 (en) | 2009-06-10 | 2010-12-16 | Astrazeneca Ab | Substituted n-[1-cyano-2-(phenyl)ethyl]piperidin-2-ylcarboxmide compounds 761 |
| WO2011154677A1 (en) | 2010-06-09 | 2011-12-15 | Astrazeneca Ab | Substituted n-[1-cyano-2-(phenyl)ethyl] 1-aminocycloalk-1-ylcarboxamide compounds - 760 |
| WO2012119941A1 (en) | 2011-03-04 | 2012-09-13 | Prozymex A/S | Peptidyl nitrilcompounds as peptidase inhibitors |
| WO2012130299A1 (en) | 2011-03-30 | 2012-10-04 | Prozymex A/S | Peptidase inhibitors |
| US8999975B2 (en) * | 2011-09-19 | 2015-04-07 | Boehringer Ingelheim International Gmbh | Substituted N- [1-cyano-2- (phenyl) ethyl] -2-azabicyclo [2.2.1] heptane-3-carboxamide inhibitors of cathepsin C |
| WO2015032943A1 (en) | 2013-09-09 | 2015-03-12 | Prozymex A/S | Peptidyl nitril compounds as dipeptidyl peptidase i inhibitors |
-
2014
- 2014-09-08 WO PCT/EP2014/069081 patent/WO2015032943A1/en not_active Ceased
- 2014-09-08 EA EA201690561A patent/EA029030B1/ru not_active IP Right Cessation
- 2014-09-08 CA CA2923484A patent/CA2923484C/en active Active
- 2014-09-08 AU AU2014317048A patent/AU2014317048B2/en active Active
- 2014-09-08 CN CN201480049595.8A patent/CN105612149A/zh active Pending
- 2014-09-08 US US14/917,147 patent/US9856228B2/en active Active
- 2014-09-08 WO PCT/EP2014/069088 patent/WO2015032945A1/en not_active Ceased
- 2014-09-08 EP EP14761986.0A patent/EP3044214B1/en active Active
- 2014-09-08 DK DK14761986.0T patent/DK3044214T3/da active
- 2014-09-08 JP JP2016539571A patent/JP6408008B2/ja active Active
- 2014-09-08 SG SG11201601150WA patent/SG11201601150WA/en unknown