JP2016522178A - 筋ジストロフィーにおけるアンジオテンシン - Google Patents

筋ジストロフィーにおけるアンジオテンシン Download PDF

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Publication number
JP2016522178A
JP2016522178A JP2016509119A JP2016509119A JP2016522178A JP 2016522178 A JP2016522178 A JP 2016522178A JP 2016509119 A JP2016509119 A JP 2016509119A JP 2016509119 A JP2016509119 A JP 2016509119A JP 2016522178 A JP2016522178 A JP 2016522178A
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JP
Japan
Prior art keywords
angiotensin
peptide
muscular dystrophy
body weight
amino acid
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JP2016509119A
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English (en)
Japanese (ja)
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JP2016522178A5 (enExample
Inventor
ラスナ サバールワル，
ラスナ サバールワル，
マーク シャプロー，
マーク シャプロー，
リチャード フランクリン，
リチャード フランクリン，
Original Assignee
ユニバーシティー オブ アイオワ リサーチ ファウンデーション
ユニバーシティー オブ アイオワ リサーチ ファウンデーション
タリックス オーファン， エルエルシー
タリックス オーファン， エルエルシー
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Application filed by ユニバーシティー オブ アイオワ リサーチ ファウンデーション, ユニバーシティー オブ アイオワ リサーチ ファウンデーション, タリックス オーファン， エルエルシー, タリックス オーファン， エルエルシー filed Critical ユニバーシティー オブ アイオワ リサーチ ファウンデーション
Publication of JP2016522178A publication Critical patent/JP2016522178A/ja
Publication of JP2016522178A5 publication Critical patent/JP2016522178A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/085—Angiotensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2016509119A 2013-04-19 2014-04-18 筋ジストロフィーにおけるアンジオテンシン Pending JP2016522178A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361813929P 2013-04-19 2013-04-19
US61/813,929 2013-04-19
US201361818307P 2013-05-01 2013-05-01
US61/818,307 2013-05-01
PCT/US2014/034615 WO2014189634A1 (en) 2013-04-19 2014-04-18 Angiotensins in muscular dystrophy

Publications (2)

Publication Number Publication Date
JP2016522178A true JP2016522178A (ja) 2016-07-28
JP2016522178A5 JP2016522178A5 (enExample) 2017-05-25

Family

ID=51933952

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016509119A Pending JP2016522178A (ja) 2013-04-19 2014-04-18 筋ジストロフィーにおけるアンジオテンシン

Country Status (11)

Country Link
US (2) US20160074464A1 (enExample)
EP (1) EP2986341A4 (enExample)
JP (1) JP2016522178A (enExample)
KR (1) KR20160026855A (enExample)
CN (1) CN105636645A (enExample)
AU (1) AU2014269028A1 (enExample)
BR (1) BR112015026286A2 (enExample)
CA (1) CA2909002A1 (enExample)
MX (1) MX2015014668A (enExample)
RU (1) RU2015141336A (enExample)
WO (1) WO2014189634A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2016152088A (ru) 2014-07-17 2018-08-21 Юниверсити Оф Саузерн Калифорния Способы, соединения и композиции для лечения заболеваний опорно-двигательного аппарата
US10973869B2 (en) 2017-05-17 2021-04-13 Constant Therapeutics Llc Methods of treating cardiomyopathy associated with genetic disorders
KR102885525B1 (ko) * 2018-11-06 2025-11-13 엣지와이즈 테라퓨틱스, 인크. 피리다지논 화합물 및 이의 용도
SMT202300355T1 (it) 2018-11-06 2024-01-10 Edgewise Therapeutics Inc Composti di piridazinone e loro usi
WO2020097258A1 (en) 2018-11-06 2020-05-14 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
EP4473968A3 (en) 2020-05-13 2025-03-26 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
CN118680926B (zh) * 2024-07-30 2024-12-20 北京市糖尿病研究所(北京市糖尿病防治办公室) Mas受体激动剂在制备预防或治疗多囊卵巢综合征的药物中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6235766B1 (en) * 1999-05-05 2001-05-22 Aventis Pharma Deutschland Gmbh 1-(p-thienylbenzyl)imidazoles as agonists of angiotensin (1-7) receptors, processes for their preparation, their use, and pharmaceutical preparations comprising them
JP2012502071A (ja) * 2008-09-12 2012-01-26 シャリテ−ウニヴェルズィテートメディツィーン ベルリン 急性肺損傷におけるａｎｇ−（１−７）レセプターアゴニストの使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0806230A2 (pt) * 2007-01-26 2021-05-25 Universidade Federal De Minas Gerais - Ufmg composições farmacêuticas, método para tratar a disfunção erétil e método para restaurar a capacidade de ereção
US9186295B2 (en) * 2011-10-25 2015-11-17 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
BR132012028005E2 (pt) * 2012-10-31 2014-11-18 Univ Minas Gerais Composições farmacêuticas contendo um agonista do receptor mas para o tratamento de doenças degenerativas musculares.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6235766B1 (en) * 1999-05-05 2001-05-22 Aventis Pharma Deutschland Gmbh 1-(p-thienylbenzyl)imidazoles as agonists of angiotensin (1-7) receptors, processes for their preparation, their use, and pharmaceutical preparations comprising them
JP2012502071A (ja) * 2008-09-12 2012-01-26 シャリテ−ウニヴェルズィテートメディツィーン ベルリン 急性肺損傷におけるａｎｇ−（１−７）レセプターアゴニストの使用

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ＨＹＰＥＲＴＥＮＳＩＯＮ, vol. 60, no. 1, JPN6018004181, 2012, pages 398, ISSN: 0003912952 *
ＪＯＵＲＮＡＬ ＯＦ ＰＨＡＲＭＡＣＯＬＯＧＹ ＡＮＤ ＥＸＰＥＲＩＭＥＮＴＡＬ ＴＨＥＲＡＰＥＵＴ, vol. 328, no. 3, JPN6018004184, 2009, pages 849 - 854, ISSN: 0003912953 *
ＪＯＵＲＮＡＬ ＯＦ ＴＨＥ ＲＥＮＩＮ−ＡＮＧＩＯＴＥＮＳＩＮ−ＡＬＤＯＳＴＥＲＯＮＥ ＳＹＳＴＥ, vol. 13, no. 4, JPN6018004186, 2012, pages 505 - 508, ISSN: 0003912954 *
脳と発達, vol. 44, no. 3, JPN6018004189, 2012, pages 234 - 238, ISSN: 0003912955 *

Also Published As

Publication number Publication date
EP2986341A4 (en) 2016-11-30
US20160074464A1 (en) 2016-03-17
CN105636645A (zh) 2016-06-01
EP2986341A1 (en) 2016-02-24
CA2909002A1 (en) 2014-11-27
RU2015141336A (ru) 2017-05-22
MX2015014668A (es) 2016-06-30
US20180221433A1 (en) 2018-08-09
BR112015026286A2 (pt) 2017-10-10
WO2014189634A1 (en) 2014-11-27
KR20160026855A (ko) 2016-03-09
AU2014269028A1 (en) 2015-10-22

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