JP2016521266A5 - - Google Patents
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- Publication number
- JP2016521266A5 JP2016521266A5 JP2016507617A JP2016507617A JP2016521266A5 JP 2016521266 A5 JP2016521266 A5 JP 2016521266A5 JP 2016507617 A JP2016507617 A JP 2016507617A JP 2016507617 A JP2016507617 A JP 2016507617A JP 2016521266 A5 JP2016521266 A5 JP 2016521266A5
- Authority
- JP
- Japan
- Prior art keywords
- combination
- ibrutinib
- lymphoma
- relapsed
- refractory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002177 L01XE27 - Ibrutinib Substances 0.000 claims 22
- XYFPWWZEPKGCCK-GOSISDBHSA-N ibrutinib Chemical compound C1=2C(N)=NC=NC=2N([C@H]2CN(CCC2)C(=O)C=C)N=C1C(C=C1)=CC=C1OC1=CC=CC=C1 XYFPWWZEPKGCCK-GOSISDBHSA-N 0.000 claims 22
- 229960001507 ibrutinib Drugs 0.000 claims 22
- 210000003719 b-lymphocyte Anatomy 0.000 claims 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 9
- 230000002062 proliferating effect Effects 0.000 claims 9
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 claims 8
- 208000031671 Large B-Cell Diffuse Lymphoma Diseases 0.000 claims 8
- 206010012818 diffuse large B-cell lymphoma Diseases 0.000 claims 8
- LQBVNQSMGBZMKD-UHFFFAOYSA-N venetoclax Chemical compound C=1C=C(Cl)C=CC=1C=1CC(C)(C)CCC=1CN(CC1)CCN1C(C=C1OC=2C=C3C=CNC3=NC=2)=CC=C1C(=O)NS(=O)(=O)C(C=C1[N+]([O-])=O)=CC=C1NCC1CCOCC1 LQBVNQSMGBZMKD-UHFFFAOYSA-N 0.000 claims 7
- 229960001183 venetoclax Drugs 0.000 claims 7
- 208000031422 Lymphocytic Chronic B-Cell Leukemia Diseases 0.000 claims 5
- 239000002775 capsule Substances 0.000 claims 4
- 208000025205 Mantle-Cell Lymphoma Diseases 0.000 claims 3
- 239000002552 dosage form Substances 0.000 claims 2
- 201000003444 follicular lymphoma Diseases 0.000 claims 2
- 201000007924 marginal zone B-cell lymphoma Diseases 0.000 claims 2
- 208000021937 marginal zone lymphoma Diseases 0.000 claims 2
- 208000024893 Acute lymphoblastic leukemia Diseases 0.000 claims 1
- 208000014697 Acute lymphocytic leukaemia Diseases 0.000 claims 1
- 208000036170 B-Cell Marginal Zone Lymphoma Diseases 0.000 claims 1
- 208000003950 B-cell lymphoma Diseases 0.000 claims 1
- 208000011691 Burkitt lymphomas Diseases 0.000 claims 1
- 201000004085 CLL/SLL Diseases 0.000 claims 1
- 206010025323 Lymphomas Diseases 0.000 claims 1
- 208000034578 Multiple myelomas Diseases 0.000 claims 1
- 201000003793 Myelodysplastic syndrome Diseases 0.000 claims 1
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
- 208000006664 Precursor Cell Lymphoblastic Leukemia-Lymphoma Diseases 0.000 claims 1
- 208000033559 Waldenström macroglobulinemia Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 208000032852 chronic lymphocytic leukemia Diseases 0.000 claims 1
- 208000023738 chronic lymphocytic leukemia/small lymphocytic lymphoma Diseases 0.000 claims 1
- 210000001280 germinal center Anatomy 0.000 claims 1
- 208000021173 high grade B-cell lymphoma Diseases 0.000 claims 1
- 208000032839 leukemia Diseases 0.000 claims 1
- 230000000306 recurrent effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361809810P | 2013-04-08 | 2013-04-08 | |
| US61/809,810 | 2013-04-08 | ||
| PCT/US2014/033378 WO2014168975A1 (en) | 2013-04-08 | 2014-04-08 | Ibrutinib combination therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019147994A Division JP6871978B2 (ja) | 2013-04-08 | 2019-08-09 | イブルチニブ併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016521266A JP2016521266A (ja) | 2016-07-21 |
| JP2016521266A5 true JP2016521266A5 (https=) | 2017-05-25 |
| JP6575952B2 JP6575952B2 (ja) | 2019-09-18 |
Family
ID=51689963
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016507617A Active JP6575952B2 (ja) | 2013-04-08 | 2014-04-08 | イブルチニブ併用療法 |
| JP2019147994A Active JP6871978B2 (ja) | 2013-04-08 | 2019-08-09 | イブルチニブ併用療法 |
| JP2021069171A Pending JP2021119150A (ja) | 2013-04-08 | 2021-04-15 | イブルチニブ併用療法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019147994A Active JP6871978B2 (ja) | 2013-04-08 | 2019-08-09 | イブルチニブ併用療法 |
| JP2021069171A Pending JP2021119150A (ja) | 2013-04-08 | 2021-04-15 | イブルチニブ併用療法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20160287592A1 (https=) |
| EP (1) | EP2983670A4 (https=) |
| JP (3) | JP6575952B2 (https=) |
| KR (1) | KR20150141971A (https=) |
| CN (2) | CN111317821A (https=) |
| AU (3) | AU2014251028A1 (https=) |
| BR (1) | BR112015025711A8 (https=) |
| CA (1) | CA2908375A1 (https=) |
| EA (1) | EA201591656A1 (https=) |
| HK (1) | HK1215374A1 (https=) |
| IL (2) | IL241710B (https=) |
| MX (2) | MX369503B (https=) |
| PH (2) | PH12015502337A1 (https=) |
| WO (1) | WO2014168975A1 (https=) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| EP3613743B1 (en) | 2008-01-04 | 2022-03-16 | Intellikine, LLC | Processes for the preparation of 1h-pyrazolo[3,4-d]pyrimidin-4-amine derivatives |
| ES2660418T3 (es) | 2008-07-16 | 2018-03-22 | Pharmacyclics Llc | Inhibidores de la tirosina quinasa de Bruton para el tratamiento de tumores sólidos |
| CN107898791A (zh) | 2010-06-03 | 2018-04-13 | 药品循环有限责任公司 | 布鲁顿酪氨酸激酶(btk)抑制剂的应用 |
| TWI674262B (zh) | 2011-01-10 | 2019-10-11 | 美商英菲尼提製藥股份有限公司 | 製備異喹啉酮之方法及異喹啉酮之固體形式 |
| US9138436B2 (en) | 2011-07-13 | 2015-09-22 | Pharmacyclics Llc | Inhibitors of Bruton's tyrosine kinase |
| EP2548877A1 (en) | 2011-07-19 | 2013-01-23 | MSD Oss B.V. | 4-(5-Membered fused pyridinyl)benzamides as BTK-inhibitors |
| BR112014001255B1 (pt) | 2011-07-19 | 2019-07-02 | Merck Sharp & Dohme B.V. | Composto, uso de um composto, combinação, composição farmacêutica, e, sal farmaceuticamente aceitável de um composto |
| EP2734205B1 (en) | 2011-07-21 | 2018-03-21 | Tolero Pharmaceuticals, Inc. | Heterocyclic protein kinase inhibitors |
| JO3754B1 (ar) | 2012-06-04 | 2021-01-31 | Pharmacyclics Llc | أشكال كريستالين لمثبط أنزيم كيناز تيروسين بروتون |
| US8828998B2 (en) | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
| CN104704129A (zh) | 2012-07-24 | 2015-06-10 | 药品循环公司 | 与对布鲁顿酪氨酸激酶(btk)抑制剂的抗性相关的突变 |
| EP2914296B2 (en) | 2012-11-01 | 2021-09-29 | Infinity Pharmaceuticals, Inc. | Treatment of cancers using pi3 kinase isoform modulators |
| MX394360B (es) | 2013-03-14 | 2025-03-24 | Sumitomo Pharma Oncology Inc | Inhibidores de jak2 y alk2 y metodos para su uso. |
| HK1222766A1 (zh) | 2013-03-15 | 2017-07-14 | G1治疗公司 | 高效的抗赘生剂和抗增生剂 |
| DK2968290T3 (da) | 2013-03-15 | 2019-11-25 | G1 Therapeutics Inc | Transient beskyttelse af normale celler under kemoterapi |
| CA2919996A1 (en) * | 2013-08-02 | 2015-02-05 | Pharmacyclics Llc | Methods for the treatment of solid tumors |
| US9415050B2 (en) | 2013-08-12 | 2016-08-16 | Pharmacyclics Llc | Methods for the treatment of HER2 amplified cancer |
| US9795604B2 (en) | 2013-10-25 | 2017-10-24 | Pharmacyclics Llc | Methods of treating and preventing graft versus host disease |
| EA201691169A1 (ru) | 2013-12-05 | 2016-09-30 | Асерта Фарма Б.В. | Терапевтическая комбинация ингибитора pi3k и ингибитора btk |
| WO2015143400A1 (en) | 2014-03-20 | 2015-09-24 | Pharmacyclics, Inc. | Phospholipase c gamma 2 and resistance associated mutations |
| JP6528779B2 (ja) | 2014-03-25 | 2019-06-12 | 小野薬品工業株式会社 | びまん性大細胞型b細胞リンパ腫の予防および/または治療剤 |
| US9937171B2 (en) | 2014-04-11 | 2018-04-10 | Acerta Pharma B.V. | Methods of blocking the CXCR-4/SDF-1 signaling pathway with inhibitors of bruton's tyrosine kinase |
| WO2015160975A2 (en) | 2014-04-16 | 2015-10-22 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| WO2015161285A1 (en) | 2014-04-17 | 2015-10-22 | G1 Therapeutics, Inc. | Tricyclic lactams for use in the protection of hematopoietic stem and progenitor cells against ionizing radiation |
| CN105017256A (zh) | 2014-04-29 | 2015-11-04 | 浙江导明医药科技有限公司 | 多氟化合物作为布鲁顿酪氨酸激酶抑制剂 |
| US9949971B2 (en) | 2014-06-17 | 2018-04-24 | Acerta Pharma B.V. | Therapeutic combinations of a BTK inhibitor, a PI3K inhibitor and/or a JAK-2 inhibitor |
| MA40596B1 (fr) * | 2014-08-11 | 2021-12-31 | Acerta Pharma Bv | Combinaisons thérapeutiques d'un inhibiteur de btk et d'un inhibiteur de bcl-2 |
| WO2016040848A1 (en) | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors |
| WO2016040858A1 (en) | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Combinations and dosing regimes to treat rb-positive tumors |
| TW201628622A (zh) * | 2014-11-17 | 2016-08-16 | 製藥公司 | Tlr抑制劑與布魯頓氏(bruton's)酪胺酸激酶抑制劑之組合 |
| WO2016090255A1 (en) * | 2014-12-05 | 2016-06-09 | Sriram Balasubramanian | Biological markers for predicting responsiveness to ibrutinib and r-chop combination therapy and methods of using the same |
| IL315294A (en) | 2015-03-03 | 2024-10-01 | Pharmacyclics Llc | Pharmaceutical formulations of bruton's tyrosine kinase inhibitor |
| US9717745B2 (en) | 2015-03-19 | 2017-08-01 | Zhejiang DTRM Biopharma Co. Ltd. | Pharmaceutical compositions and their use for treatment of cancer and autoimmune diseases |
| MA41827A (fr) * | 2015-03-27 | 2018-01-30 | Pharmacyclics Llc | Formes solvatées d'un inhibiteur de la tyrosine kinase de bruton |
| HK1251165A1 (en) | 2015-04-13 | 2019-01-25 | Daiichi Sankyo Company, Limited | Treatment method combining mdm2 inhibitor and btk inhibitor |
| WO2016172199A1 (en) * | 2015-04-20 | 2016-10-27 | Epizyme, Inc. | Combination therapy for treating cancer |
| PL3954690T3 (pl) | 2015-07-02 | 2023-08-14 | Acerta Pharma B.V. | Postacie stałe i formulacje (s)-4-(8-amino-3-(1-(but-2-ynoilo)pirolidyn-2-ylo)imidazo[1,5-a]-pirazyn-1-ylo)-n-(pirydyn-2-ylo)benzamidu |
| JP2018522028A (ja) * | 2015-07-31 | 2018-08-09 | ファーマサイクリックス エルエルシー | ブルトン型チロシンキナーゼ阻害剤の組み合わせ及びそれらの使用 |
| US20180207164A1 (en) * | 2015-08-03 | 2018-07-26 | Gilead Sciences, Inc. | Combination therapies for treating cancers |
| TW201726130A (zh) * | 2015-10-02 | 2017-08-01 | 基利科學股份有限公司 | 用於治療癌症之組合療法 |
| WO2017087947A2 (en) * | 2015-11-19 | 2017-05-26 | Pharmacyclics Llc | Method of treatment of follicular lymphoma with a btk inhibitor |
| RU2754507C2 (ru) | 2016-06-24 | 2021-09-02 | Инфинити Фармасьютикалз, Инк. | Комбинированная терапия |
| JP7106462B2 (ja) | 2016-07-01 | 2022-07-26 | ジー1 セラピューティクス, インコーポレイテッド | N-(ヘテロアリール)-ピロロ[3,2-d]ピリミジン-2-アミンの合成 |
| JP2019524700A (ja) | 2016-07-14 | 2019-09-05 | ミングサイト ファーマシューティカルズ,インク. | 癌の処置 |
| WO2018021890A1 (ko) * | 2016-07-29 | 2018-02-01 | 이화여자대학교 산학협력단 | 크로메논 유도체 및 이를 포함하는 항암용 조성물 |
| CA3029851A1 (en) * | 2016-07-29 | 2018-02-01 | Oncternal Therapeutics, Inc. | Uses of indoline compounds such as tk216 for the treatment of cancer |
| IL303038B2 (en) | 2016-12-05 | 2024-08-01 | G1 Therapeutics Inc | Preservation of immune response during chemotherapy regimens |
| ES2928773T3 (es) | 2017-01-17 | 2022-11-22 | Heparegenix Gmbh | Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos |
| MX393601B (es) * | 2017-05-18 | 2025-03-21 | Jiangsu Hengrui Medicine Co | Uso del inhibidor mejorador de homologo zeste 2 (ezh2) combinado con el inhibidor tirosina cinasa de bruton (btk) en la preparacion de farmacos para tratar tumores. |
| WO2019058386A1 (en) * | 2017-09-19 | 2019-03-28 | Cipla Limited | COMPOSITIONS COMPRISING IBRUTINIB AND AN ALKALOID HAVING IMPROVED BIOAVAILABILITY |
| TW201922256A (zh) | 2017-10-27 | 2019-06-16 | 中國大陸商浙江導明醫藥科技有限公司 | 治療淋巴樣惡性疾病之方法 |
| EP3768258A4 (en) * | 2018-03-21 | 2022-01-12 | MEI Pharma, Inc. | COMBINATION THERAPY |
| CN112533602A (zh) | 2018-04-05 | 2021-03-19 | 大日本住友制药肿瘤公司 | Axl激酶抑制剂及其用途 |
| CN117838695A (zh) | 2018-04-13 | 2024-04-09 | 住友制药肿瘤公司 | 用于治疗骨髓增殖性肿瘤和与癌症相关的纤维化的pim激酶抑制剂 |
| US20210121466A1 (en) | 2018-05-03 | 2021-04-29 | Juno Therapeutics, Inc. | Combination therapy of a chimeric antigen receptor (car) t cell therapy and a kinase inhibitor |
| MX2021000977A (es) | 2018-07-26 | 2021-04-12 | Sumitomo Pharma Oncology Inc | Metodos para tratar enfermedades asociadas con expresion anormal de receptor de activina a tipo 1 (acvr1) e inhibidores de acvr1 para uso en los mismos. |
| TWI725488B (zh) * | 2018-07-31 | 2021-04-21 | 大陸商蘇州亞盛藥業有限公司 | Bcl-2抑制劑與化療藥的組合產品及其在預防及/或治療疾病中的用途 |
| RS67557B1 (sr) | 2018-08-24 | 2026-01-30 | Pharmacosmos Holding As | Unapređena sinteza 1,4-diazaspiro[5.5]undekan-3-ona |
| WO2020046767A1 (en) * | 2018-08-26 | 2020-03-05 | Trovagene, Inc. | Plk1 target phosphorylation status and treatment of cancer with plk1 inhibitors |
| US20220362357A1 (en) * | 2018-08-31 | 2022-11-17 | Stichting Radboud Universitair Medisch Centrum | Synergistic Combinations of Amino Acid Depletion Agent Sensitizers (AADAS) and Amino Acid Depletion Agents (AADA), and Therapeutic Methods of Use Thereof |
| CN112512527A (zh) * | 2018-09-12 | 2021-03-16 | 杭州索元生物医药股份有限公司 | 恩扎妥林和btk抑制剂的组合及其用途 |
| CA3133376A1 (en) * | 2018-11-30 | 2020-06-04 | Aptose Biosciences Inc. | Combination therapy with 2,3-dihydro-isoindole-1-one compounds and methods for treating patients with various mutations |
| US20200171034A1 (en) * | 2018-11-30 | 2020-06-04 | Janssen Biotech, Inc. | Methods Of Treating Follicular Lymphoma |
| NZ778055A (en) | 2019-02-12 | 2025-11-28 | Sumitomo Pharma America Inc | Formulations comprising heterocyclic protein kinase inhibitors |
| SG11202108770TA (en) * | 2019-02-15 | 2021-09-29 | Janssen Biotech Inc | Combination therapy for treatment of b-cell malignancies |
| EP3938399A4 (en) * | 2019-03-13 | 2023-04-12 | The Brigham & Women's Hospital, Inc. | TARGETED REGULATORY B CELLS AND THEIR REGULATORS FOR CANCER IMMUNOTHERAPY |
| US20230100235A1 (en) * | 2020-02-05 | 2023-03-30 | Carna Biosciences, Inc. | Anticancer agent composition |
| US10988479B1 (en) | 2020-06-15 | 2021-04-27 | G1 Therapeutics, Inc. | Morphic forms of trilaciclib and methods of manufacture thereof |
| GB202009764D0 (en) * | 2020-06-26 | 2020-08-12 | Cambridge Entpr Ltd | Therapeutic treatment using protein kinase c (pkc) inhibitors and cytotoxic agents |
| WO2023275330A1 (en) * | 2021-06-30 | 2023-01-05 | Janssen Pharmaceutica Nv | Treatments for diffuse large b-cell lymphoma |
| WO2023285677A1 (en) * | 2021-07-16 | 2023-01-19 | Spexis Ag | Pharmaceutical combinations for treating cancer |
| WO2023220655A1 (en) | 2022-05-11 | 2023-11-16 | Celgene Corporation | Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy |
| CN115554301A (zh) * | 2022-10-24 | 2023-01-03 | 徐诺药业(南京)有限公司 | Hdac抑制剂和伊布替尼在制备预防或者治疗套细胞淋巴瘤的药物中的用途 |
| EP4611753A1 (en) | 2022-10-31 | 2025-09-10 | Sumitomo Pharma America, Inc. | Pim1 inhibitor for treating myeloproliferative neoplasms |
| WO2025249980A1 (ko) * | 2024-05-31 | 2025-12-04 | (주)노보메디슨 | 림프종의 예방 또는 치료를 위한 포셀티닙의 병용투여 요법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008001156A1 (en) * | 2006-06-26 | 2008-01-03 | Centre Regional De Lutte Contre Le Cancer - Centre Francois Baclesse | CANCER THERAPY USING BcI-XL-SPECIFIC siNA |
| BRPI0622054B8 (pt) * | 2006-09-22 | 2021-05-25 | Oxford Amherst Llc | composto e composição farmacêutica |
| JP2010519910A (ja) * | 2007-03-02 | 2010-06-10 | エムディーアールエヌエー,インコーポレイテッド | Bcl2遺伝子の発現を抑制するための核酸化合物およびその使用 |
| JP5832721B2 (ja) * | 2007-03-14 | 2015-12-16 | バイオンシル・エス.アール.エル.Bionsil S.R.L. | 上皮腫瘍細胞における薬剤耐性のモジュレータ化合物 |
| JP5464609B2 (ja) * | 2008-03-27 | 2014-04-09 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | チューブリン重合阻害剤としてのキナゾリノン誘導体 |
| NZ595708A (en) * | 2009-05-26 | 2014-03-28 | Abbvie Bahamas Ltd | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
| CN107898791A (zh) * | 2010-06-03 | 2018-04-13 | 药品循环有限责任公司 | 布鲁顿酪氨酸激酶(btk)抑制剂的应用 |
| CN104768581A (zh) * | 2012-09-07 | 2015-07-08 | 吉宁特有限公司 | II型抗CD20抗体与选择性Bcl-2抑制剂的组合治疗 |
-
2014
- 2014-04-08 HK HK16103284.1A patent/HK1215374A1/zh unknown
- 2014-04-08 AU AU2014251028A patent/AU2014251028A1/en not_active Abandoned
- 2014-04-08 CN CN201911007617.5A patent/CN111317821A/zh active Pending
- 2014-04-08 CN CN201480025176.0A patent/CN105263496A/zh active Pending
- 2014-04-08 KR KR1020157029969A patent/KR20150141971A/ko not_active Ceased
- 2014-04-08 BR BR112015025711A patent/BR112015025711A8/pt not_active Application Discontinuation
- 2014-04-08 JP JP2016507617A patent/JP6575952B2/ja active Active
- 2014-04-08 MX MX2015013970A patent/MX369503B/es active IP Right Grant
- 2014-04-08 EA EA201591656A patent/EA201591656A1/ru unknown
- 2014-04-08 CA CA2908375A patent/CA2908375A1/en not_active Abandoned
- 2014-04-08 WO PCT/US2014/033378 patent/WO2014168975A1/en not_active Ceased
- 2014-04-08 US US14/778,536 patent/US20160287592A1/en not_active Abandoned
- 2014-04-08 EP EP14782886.7A patent/EP2983670A4/en not_active Withdrawn
-
2015
- 2015-09-20 IL IL241710A patent/IL241710B/en active IP Right Grant
- 2015-10-02 MX MX2019013429A patent/MX2019013429A/es unknown
- 2015-10-08 PH PH12015502337A patent/PH12015502337A1/en unknown
-
2018
- 2018-11-14 IL IL263026A patent/IL263026A/en unknown
-
2019
- 2019-05-07 AU AU2019203205A patent/AU2019203205A1/en not_active Abandoned
- 2019-08-01 US US16/529,467 patent/US20200368235A1/en not_active Abandoned
- 2019-08-09 JP JP2019147994A patent/JP6871978B2/ja active Active
-
2020
- 2020-12-01 PH PH12020552065A patent/PH12020552065A1/en unknown
-
2021
- 2021-01-07 AU AU2021200066A patent/AU2021200066A1/en not_active Abandoned
- 2021-04-15 JP JP2021069171A patent/JP2021119150A/ja active Pending
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