JP2016521114A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016521114A5 JP2016521114A5 JP2015562041A JP2015562041A JP2016521114A5 JP 2016521114 A5 JP2016521114 A5 JP 2016521114A5 JP 2015562041 A JP2015562041 A JP 2015562041A JP 2015562041 A JP2015562041 A JP 2015562041A JP 2016521114 A5 JP2016521114 A5 JP 2016521114A5
- Authority
- JP
- Japan
- Prior art keywords
- macrophages
- polypeptide
- differentiation
- expression
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361781220P | 2013-03-14 | 2013-03-14 | |
| US61/781,220 | 2013-03-14 | ||
| PCT/EP2014/054441 WO2014139883A1 (en) | 2013-03-14 | 2014-03-07 | Molecular targets and compounds, and methods to identify the same, useful in the treatment of fibrotic diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016521114A JP2016521114A (ja) | 2016-07-21 |
| JP2016521114A5 true JP2016521114A5 (https=) | 2017-04-06 |
| JP6437467B2 JP6437467B2 (ja) | 2018-12-19 |
Family
ID=50239627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562041A Active JP6437467B2 (ja) | 2013-03-14 | 2014-03-07 | 線維化疾患治療において有用な分子標的及び化合物、並びにこれらの同定方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20160054304A1 (https=) |
| EP (1) | EP2972322B1 (https=) |
| JP (1) | JP6437467B2 (https=) |
| WO (1) | WO2014139883A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018149978A1 (en) * | 2017-02-16 | 2018-08-23 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | ALTERNATIVE ACTIVATION OF MACROPHAGES (M2 CELLS) THROUGH THE POLYAMINE-eIF5a-HYPUSINE AXIS |
| US11536723B2 (en) | 2017-05-24 | 2022-12-27 | Mayo Foundation For Medical Education And Research | Integrated immunoassay |
| US12233094B2 (en) | 2017-11-29 | 2025-02-25 | Spinalcyte, Llc | Interaction of fibroblasts and immune cells for activation and uses thereof |
| CA3110618A1 (en) * | 2018-08-29 | 2020-03-05 | Riptide Bioscience, Inc. | Peptides having immunomodulatory properties |
| GB201900724D0 (en) * | 2019-01-18 | 2019-03-06 | King S College London | Antibody |
| MX2021006297A (es) | 2019-08-01 | 2021-09-08 | Illumina Inc | Celdas de flujo. |
| CN114269945B (zh) | 2019-08-23 | 2024-07-19 | 宝洁公司 | 鉴定纤维化过程的调节物的方法 |
| WO2021141733A1 (en) | 2020-01-07 | 2021-07-15 | The Procter & Gamble Company | Method of modulating a fibrotic condition |
| EP4213901A4 (en) * | 2020-09-21 | 2025-03-05 | Massachusetts Institute of Technology | COMPOUNDS, TARGETS AND PATHWAYS FOR MODULATION OF MACROPHAGES |
| CN117959323B (zh) * | 2024-01-12 | 2025-01-21 | 南方医科大学南方医院 | 环状rna在制备防治放射性肝纤维化的药物中的应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US5354844A (en) | 1989-03-16 | 1994-10-11 | Boehringer Ingelheim International Gmbh | Protein-polycation conjugates |
| US5693622A (en) | 1989-03-21 | 1997-12-02 | Vical Incorporated | Expression of exogenous polynucleotide sequences cardiac muscle of a mammal |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| EP0786522A2 (en) | 1992-07-17 | 1997-07-30 | Ribozyme Pharmaceuticals, Inc. | Enzymatic RNA molecules for treatment of stenotic conditions |
| FR2714830B1 (fr) | 1994-01-10 | 1996-03-22 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2715847B1 (fr) | 1994-02-08 | 1996-04-12 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucléiques, préparation et utilisations. |
| FR2727679B1 (fr) | 1994-12-05 | 1997-01-03 | Rhone Poulenc Rorer Sa | Nouveaux agents de transfection et leurs applications pharmaceutiques |
| FR2730637B1 (fr) | 1995-02-17 | 1997-03-28 | Rhone Poulenc Rorer Sa | Composition pharmaceutique contenant des acides nucleiques, et ses utilisations |
| GB9620749D0 (en) | 1996-10-04 | 1996-11-20 | Brax Genomics Ltd | Identifying antisense oligonucleotides |
| AU8280798A (en) | 1997-07-03 | 1999-01-25 | Thomas Jefferson University | An improved method for design and selection of efficacious antisense oligonucleotides |
| US6004753A (en) * | 1997-12-01 | 1999-12-21 | Incyte Pharmaceuticals, Inc. | Human S1-5 ECMP-like protein |
| GB2335035B (en) | 1998-03-03 | 2003-05-28 | Brax Genomics Ltd | Screening for functional antisense agents |
| US7332337B2 (en) | 2000-05-16 | 2008-02-19 | Galapagos Nv | Viral vectors having tissue tropism for T-lymphocytes, B- and mast cells |
| JP2004123539A (ja) * | 2001-03-13 | 2004-04-22 | Japan Tobacco Inc | 新規ピラゾロピリジン化合物及び医薬用途 |
| JP2004123537A (ja) * | 2000-06-20 | 2004-04-22 | Japan Tobacco Inc | ピラゾロピリジン化合物及びその医薬用途 |
| DE60138403D1 (de) | 2000-09-26 | 2009-05-28 | Crucell Holland Bv | Adenovirale vektoren für die übertragung von genen in zellen der skelettmuskulatur oder myoblasten |
| JP2005300158A (ja) * | 2001-03-26 | 2005-10-27 | Nippon Shinyaku Co Ltd | 増殖性糸球体腎炎の予防・治療用薬物のスクリーニング方法 |
| US20030198627A1 (en) | 2001-09-01 | 2003-10-23 | Gert-Jan Arts | siRNA knockout assay method and constructs |
| AU2003301991A1 (en) * | 2002-11-13 | 2004-06-03 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with human endothelial differentiation, sphingolipid g-protein-coupled receptor 5 (edg5) |
| WO2004094636A1 (en) | 2003-04-24 | 2004-11-04 | Galapagos Genomics N.V. | Effective sirna knock-down constructs |
| WO2011087051A1 (ja) * | 2010-01-14 | 2011-07-21 | 国立大学法人金沢大学 | S1p2受容体アンタゴニストを含む粥状動脈硬化治療薬 |
| KR20130005086A (ko) * | 2011-07-05 | 2013-01-15 | 한국과학기술연구원 | 대장암 진단용 단백질 마커 피불린-4 및 이에 대한 항체를 포함하는 대장암 진단 키트 |
-
2014
- 2014-03-07 WO PCT/EP2014/054441 patent/WO2014139883A1/en not_active Ceased
- 2014-03-07 US US14/775,790 patent/US20160054304A1/en not_active Abandoned
- 2014-03-07 JP JP2015562041A patent/JP6437467B2/ja active Active
- 2014-03-07 EP EP14708865.2A patent/EP2972322B1/en active Active
-
2017
- 2017-08-04 US US15/669,213 patent/US10048250B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016521114A5 (https=) | ||
| PH12021550307A1 (en) | T Cell Receptor Constructs And Uses Thereof | |
| WO2018132739A3 (en) | T cell receptors that bind to ny-eso-1 and methods of use thereof | |
| JP2018529698A5 (https=) | ||
| EA201290027A1 (ru) | Ацилированные аналоги глюкагона | |
| WO2013096407A3 (en) | Monitoring activation times for use in determining pacing effectiveness | |
| WO2016015058A3 (en) | Methods of determining tissues and/or cell types giving rise to cell-free dna, and methods of identifying a disease or disorder using same | |
| BR112014000965B8 (pt) | Método, aparelho e meio de armazenamento não transitório | |
| MX382337B (es) | Terapia génica de globina y uso de la misma para el tratamiento de hemoglobinopatias. | |
| IN2012DN06588A (https=) | ||
| EA201500802A1 (ru) | Способы профилактики и/или лечения кардиомиопатии и устранения симптомов кардиомиопатии, фармацевтическая композиция, векторы | |
| JP2015509489A5 (https=) | ||
| GB201207585D0 (en) | An electrode and use thereof | |
| WO2018104909A3 (en) | Dna methylation profiling for t-cell immunotherapy | |
| JP2014527400A5 (https=) | ||
| WO2014179424A3 (en) | Lipidomic biomarkers | |
| WO2015158890A3 (en) | Pancreatic cancer therapy and diagnosis | |
| HUE071384T2 (hu) | Szénanyag, annak alkalmazása akkumulátorokban, eljárás az anyag elõállítására és az azt tartalmazó elektróda | |
| EA201100674A1 (ru) | Вакцина против вируса африканской чумы лошадей | |
| ES2640752T3 (es) | Agonistas del receptor 5-HT4 para el tratamiento de la demencia | |
| MX2018003697A (es) | Metodos para el tratamiento de linfoma difuso de linfocitos b grandes y uso de biomarcadores como predictores de receptividad a farmacos. | |
| CO6430497A2 (es) | Metodo o sistema que usa biomarcadores para el seguimiento de un tratamiento | |
| JP2015530094A5 (https=) | ||
| JP2017517561A5 (https=) | ||
| BR112018012660A2 (pt) | composto, sal, composto sólido, polimorfo a, polimorfo b, polimorfo c, polimorfo d, composição, método de inibição da atividade de gls1 em uma amostra biológica, métodos de tratamento de um distúrbio mediado por gls1 em um sujeito necessitado, composto, sal, solvato ou polimorfo, e uso de um composto, sal, solvato ou polimorfo |