JP2014527400A5 - - Google Patents

Download PDF

Info

Publication number
JP2014527400A5
JP2014527400A5 JP2014517664A JP2014517664A JP2014527400A5 JP 2014527400 A5 JP2014527400 A5 JP 2014527400A5 JP 2014517664 A JP2014517664 A JP 2014517664A JP 2014517664 A JP2014517664 A JP 2014517664A JP 2014527400 A5 JP2014527400 A5 JP 2014527400A5
Authority
JP
Japan
Prior art keywords
diabetes
apociii
population
secreting cells
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014517664A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014527400A (ja
JP6242790B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2012/062371 external-priority patent/WO2013000920A2/en
Publication of JP2014527400A publication Critical patent/JP2014527400A/ja
Publication of JP2014527400A5 publication Critical patent/JP2014527400A5/ja
Application granted granted Critical
Publication of JP6242790B2 publication Critical patent/JP6242790B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014517664A 2011-06-27 2012-06-26 糖尿病の治療および/または発症抑制を行うための候補化合物を同定する方法 Expired - Fee Related JP6242790B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161501480P 2011-06-27 2011-06-27
US61/501,480 2011-06-27
PCT/EP2012/062371 WO2013000920A2 (en) 2011-06-27 2012-06-26 Methods for treating and/or limiting development of diabetes

Publications (3)

Publication Number Publication Date
JP2014527400A JP2014527400A (ja) 2014-10-16
JP2014527400A5 true JP2014527400A5 (https=) 2015-06-11
JP6242790B2 JP6242790B2 (ja) 2017-12-06

Family

ID=46331358

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014517664A Expired - Fee Related JP6242790B2 (ja) 2011-06-27 2012-06-26 糖尿病の治療および/または発症抑制を行うための候補化合物を同定する方法

Country Status (6)

Country Link
US (6) US8557513B2 (https=)
EP (1) EP2724155B1 (https=)
JP (1) JP6242790B2 (https=)
KR (1) KR101937260B1 (https=)
CN (1) CN103620404B (https=)
WO (1) WO2013000920A2 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8557513B2 (en) * 2011-06-27 2013-10-15 Biocrine Ab Methods for treating and/or limiting development of diabetes
JP6322209B2 (ja) 2012-12-18 2018-05-09 ビオクリネ エービー 糖尿病の治療および/または発症抑制のための方法
JP2014161257A (ja) * 2013-02-22 2014-09-08 Univ Of Tokyo 多能性幹細胞から膵ランゲルハンス島を製造する方法
AU2014218583A1 (en) 2013-02-25 2015-10-15 Imetabolic Biopharma, Llc Apolipoprotein c3 (apociii) antagonists and methods of their use to remove apociii inhibition of lipoprotein lipase (lpl)
PL2970463T3 (pl) * 2013-03-13 2018-04-30 Biocrine Ab Sposoby leczenia i/lub ograniczania rozwoju cukrzycy
KR20150046852A (ko) * 2013-10-23 2015-05-04 삼성전자주식회사 전자 장치 및 전자 장치의 암호를 이용한 인증 방법
KR102206054B1 (ko) * 2014-05-09 2021-01-21 삼성전자주식회사 지문 처리 방법 및 그 전자 장치
US9474951B2 (en) * 2015-01-21 2016-10-25 William Chuang Golf tee structures, assemblies, and systems with improved accuracy
WO2016128358A1 (en) 2015-02-09 2016-08-18 Biocrine Ab Methods for treating and/or limiting development of diabetes in subjects with amyotrophic lateral sclerosis
JP7341916B2 (ja) * 2015-04-01 2023-09-11 ビーエーエスエフ エーエス アポc3を低下させるためのチアオキソ化合物の使用
AU2017292184A1 (en) 2016-07-08 2019-02-07 Staten Biotechnology B.V. Anti-Apoc3 antibodies and methods of use thereof
JP2020517242A (ja) 2017-04-21 2020-06-18 スターテン・バイオテクノロジー・ベー・フェー 抗ApoC3抗体およびその使用方法
US10538583B2 (en) 2017-10-31 2020-01-21 Staten Biotechnology B.V. Anti-APOC3 antibodies and compositions thereof
KR20200074975A (ko) 2017-10-31 2020-06-25 스태튼 바이오테크놀로지 비.브이. 항-ApoC3 항체 및 이의 사용 방법
JP2021530476A (ja) 2018-07-19 2021-11-11 バイオクライン アーベーBiocrine Ab 糖尿病を治療するための方法および試薬
US11310268B2 (en) 2019-05-06 2022-04-19 Secureworks Corp. Systems and methods using computer vision and machine learning for detection of malicious actions
US11381589B2 (en) 2019-10-11 2022-07-05 Secureworks Corp. Systems and methods for distributed extended common vulnerabilities and exposures data management

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6492325B1 (en) * 1998-05-22 2002-12-10 Boys Town National Research Hospital Use of α1β1 integrin receptor inhibitors and TGF-β1 inhibitors in the treatment of kidney disease
US20030083242A1 (en) 1998-11-06 2003-05-01 Alphonse Galdes Methods and compositions for treating or preventing peripheral neuropathies
CA2395136A1 (en) * 1999-12-22 2001-06-28 The Scripps Research Institute Angiogenesis and vascular permeability modulators and inhibitors
EP1414491A4 (en) 2001-07-09 2005-07-06 Elan Pharm Inc METHOD OF INHIBITING THE TOXICITY OF AMYLOID
ES2398110T3 (es) 2003-04-29 2013-03-13 Biocrine Ab ApoCIII y tratamiento y diagnóstico de la diabetes
US20060094682A1 (en) * 2004-10-29 2006-05-04 Odyssey Thera, Inc. Kinase inhibitors for the treatment of diabetes and obesity
WO2006110082A1 (en) * 2005-04-11 2006-10-19 Astrazeneca Ab A method and a kit for diagnosing type 2 diabetes, metabolic syndrome, sub clinical atherosclerosis, myocardial infarct, stroke or clinical manifestations of diabetes.
US20090060843A1 (en) 2007-08-31 2009-03-05 Biocrine Ab Non-Invasive In Vivo Imaging and Methods for Treating Type I Diabetes
US20110008901A1 (en) * 2009-07-07 2011-01-13 Kiernan Urban A Apolipoprotein ciii in pre- and type 2 diabetes
US8557513B2 (en) * 2011-06-27 2013-10-15 Biocrine Ab Methods for treating and/or limiting development of diabetes

Similar Documents

Publication Publication Date Title
JP2014527400A5 (https=)
Bhattacharyya et al. FibronectinEDA promotes chronic cutaneous fibrosis through Toll-like receptor signaling
Takahashi et al. Cancer cells co-opt the neuronal redox-sensing channel TRPA1 to promote oxidative-stress tolerance
Wasserman et al. The vasculature in prediabetes
Xiao et al. EZH2 enhances the differentiation of fibroblasts into myofibroblasts in idiopathic pulmonary fibrosis
Omote et al. Role of the TNF pathway in the progression of diabetic nephropathy in KK-Ay mice
Varga et al. Antitransforming growth factor-β therapy in fibrosis: recent progress and implications for systemic sclerosis
Gil et al. Heparanase is essential for the development of diabetic nephropathy in mice
Chau et al. MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways
Zheng et al. The coordinated roles of miR-26a and miR-30c in regulating TGFβ1-induced epithelial-to-mesenchymal transition in diabetic nephropathy
Alimonti et al. A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
Ren et al. Nitric oxide synthase inhibition abolishes exercise-mediated protection against isoproterenol-induced cardiac hypertrophy in female mice
Wettwer et al. The new antiarrhythmic drug vernakalant: ex vivo study of human atrial tissue from sinus rhythm and chronic atrial fibrillation
Barlow et al. Do skeletal muscle-secreted factors influence the function of pancreatic β-cells?
Zhou et al. Wnt/β-catenin signaling and renin–angiotensin system in chronic kidney disease
Morales et al. Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression
Liu et al. Circulating microRNA-146a and microRNA-21 predict left ventricular remodeling after ST-elevation myocardial infarction
Ding et al. New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis
WO2013000920A3 (en) Methods for identifying candidate compounds for treating and/or limiting development of diabetes
Sayar et al. EGFR inhibitors erlotinib and lapatinib ameliorate epidermal blistering in pemphigus vulgaris in a non‐linear, V‐shaped relationship
Xue et al. Activation of HIF-1 by metallothionein contributes to cardiac protection in the diabetic heart
Lv et al. Metabolic regulation of the glioblastoma stem cell epitranscriptome by malate dehydrogenase 2
Rosselot et al. Myc is required for adaptive β-cell replication in young mice but is not sufficient in one-year-old mice fed with a high-fat diet
Saito et al. Mechanism of impairment on liver regeneration in elderly patients: role of hepatic stellate cell function
Koga et al. The bone morphogenic protein inhibitor, noggin, reduces glycemia and vascular inflammation in db/db mice