JP2016519101A5 - - Google Patents
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- JP2016519101A5 JP2016519101A5 JP2016505926A JP2016505926A JP2016519101A5 JP 2016519101 A5 JP2016519101 A5 JP 2016519101A5 JP 2016505926 A JP2016505926 A JP 2016505926A JP 2016505926 A JP2016505926 A JP 2016505926A JP 2016519101 A5 JP2016519101 A5 JP 2016519101A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- omega
- acid
- fatty acid
- fatty
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000203 mixture Substances 0.000 claims 15
- MBMBGCFOFBJSGT-KUBAVDMBSA-N Docosahexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims 7
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims 7
- QRYRORQUOLYVBU-VBKZILBWSA-N Salvin Chemical compound CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims 6
- OAIJSZIZWZSQBC-LWRKPGOESA-N Lycopene Natural products CC(C)=CCC\C(C)=C/C=C/C(/C)=C\C=C\C(\C)=C/C=C/C=C(/C)\C=C\C=C(\C)/C=C/C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-LWRKPGOESA-N 0.000 claims 4
- YVLPJIGOMTXXLP-UUKUAVTLSA-N 15,15'-cis-Phytoene Natural products C(=C\C=C/C=C(\CC/C=C(\CC/C=C(\CC/C=C(\C)/C)/C)/C)/C)(\CC/C=C(\CC/C=C(\CC/C=C(\C)/C)/C)/C)/C YVLPJIGOMTXXLP-UUKUAVTLSA-N 0.000 claims 2
- 229960005135 Eicosapentaenoic Acid Drugs 0.000 claims 2
- JAZBEHYOTPTENJ-JLNKQSITSA-N Eicosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- 241000227653 Lycopersicon Species 0.000 claims 2
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims 2
- 229940012843 Omega-3 Fatty Acids Drugs 0.000 claims 2
- 229960004363 doconexent Drugs 0.000 claims 2
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 2
- 229940090949 docosahexaenoic acid Drugs 0.000 claims 2
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 235000012661 lycopene Nutrition 0.000 claims 2
- 239000001751 lycopene Substances 0.000 claims 2
- 229960004999 lycopene Drugs 0.000 claims 2
- 239000006014 omega-3 oil Substances 0.000 claims 2
- OVSVTCFNLSGAMM-UZFNGAIXSA-N (12E,16Z,18E,22E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,10,12,14,16,18,22,26,30-decaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CC=C\C=C(/C)\C=C\C=C(C)CCC=C(C)CCC=C(C)C OVSVTCFNLSGAMM-UZFNGAIXSA-N 0.000 claims 1
- KBPHJBAIARWVSC-RGZFRNHPSA-N (1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1R,4R)-4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 claims 1
- 229960002747 Betacarotene Drugs 0.000 claims 1
- 229960005375 Lutein Drugs 0.000 claims 1
- KBPHJBAIARWVSC-NRHWGSPPSA-N Lutein Natural products O[C@H]1C=C(C)[C@H](/C=C/C(=C\C=C\C(=C/C=C/C=C(\C=C\C=C(/C=C/C=2C(C)(C)C[C@H](O)CC=2C)\C)/C)\C)/C)C(C)(C)C1 KBPHJBAIARWVSC-NRHWGSPPSA-N 0.000 claims 1
- OVSVTCFNLSGAMM-WHQNONBVSA-N Phytofluene Natural products C(=C\C=C/C=C(\CC/C=C(\CC/C=C(\CC/C=C(\C)/C)/C)/C)/C)(\C=C\C=C(/CC/C=C(\CC/C=C(\C)/C)/C)\C)/C OVSVTCFNLSGAMM-WHQNONBVSA-N 0.000 claims 1
- 229960001295 Tocopherol Drugs 0.000 claims 1
- 230000003110 anti-inflammatory Effects 0.000 claims 1
- OENHQHLEOONYIE-VYAWBVGESA-N beta-Carotene Natural products CC=1CCCC(C)(C)C=1\C=C\C(\C)=C/C=C/C(/C)=C\C=C\C=C(\C)/C=C/C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-VYAWBVGESA-N 0.000 claims 1
- 235000013734 beta-carotene Nutrition 0.000 claims 1
- 239000011648 beta-carotene Substances 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 235000012680 lutein Nutrition 0.000 claims 1
- 239000001656 lutein Substances 0.000 claims 1
- 235000011765 phytoene Nutrition 0.000 claims 1
- 235000002677 phytofluene Nutrition 0.000 claims 1
- -1 phytosterol Chemical compound 0.000 claims 1
- 230000002195 synergetic Effects 0.000 claims 1
- 235000010384 tocopherol Nutrition 0.000 claims 1
- 239000011732 tocopherol Substances 0.000 claims 1
- 229930003799 tocopherols Natural products 0.000 claims 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 claims 1
Claims (10)
- オメガ−３脂肪酸とカルノシン酸とトマトリコペンとを含む、組成物。
- 前記組成物が、フィトエン、フィトフルエン、β−カロテン、トコフェロール、フィトステロール、ルテイン、またはそれらの任意の組み合わせをさらに含む、請求項１に記載の組成物。
- オメガ−３脂肪酸対トマトリコペンのモル濃度比が２０００：１〜１０：１であるか、オメガ−３脂肪酸対カルノシン酸のモル濃度比が１５００：１〜２：１であるか、オメガ−３脂肪酸対トマトリコペン対カルノシン酸のモル濃度比が２０００：１：５〜２：１：１である、請求項１に記載の組成物。
- 前記組成物が相乗的抗炎症効果を有する、請求項１に記載の組成物。
- 前記組成物が経口組成物である、請求項１に記載の組成物。
- 前記オメガ−３脂肪酸が、ドコサヘキサエン酸、エイコサペンタエン酸、またはそれらの組み合わせである、請求項１に記載の組成物。
- 炎症を処置するための、オメガ−３脂肪酸とトマトリコペンとを含む組成物の使用。
- オメガ−３脂肪酸対トマトリコペンのモル濃度比が２０００：１〜１０：１である、請求項７に記載の使用。
- 前記オメガ−３脂肪酸が、ドコサヘキサエン酸、エイコサペンタエン酸、またはそれらの組み合わせである、請求項８に記載の使用。
- 炎症を処置するための、請求項１〜６のいずれか１項に記載の組成物の使用。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361808246P | 2013-04-04 | 2013-04-04 | |
| US61/808,246 | 2013-04-04 | ||
| PCT/IL2014/050329 WO2014162313A1 (en) | 2013-04-04 | 2014-04-03 | Anti-inflammatory synergistic combinations comprising omega-3 fatty acid and tomato lycopene |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018224936A Division JP6803898B2 (ja) | 2013-04-04 | 2018-11-30 | オメガ−３脂肪酸およびトマトリコペンを含む抗炎症性相乗的組み合わせ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016519101A JP2016519101A (ja) | 2016-06-30 |
| JP2016519101A5 true JP2016519101A5 (ja) | 2017-05-18 |
Family
ID=51657661
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016505926A Pending JP2016519101A (ja) | 2013-04-04 | 2014-04-03 | オメガ−３脂肪酸およびトマトリコペンを含む抗炎症性相乗的組み合わせ |
| JP2018224936A Active JP6803898B2 (ja) | 2013-04-04 | 2018-11-30 | オメガ−３脂肪酸およびトマトリコペンを含む抗炎症性相乗的組み合わせ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018224936A Active JP6803898B2 (ja) | 2013-04-04 | 2018-11-30 | オメガ−３脂肪酸およびトマトリコペンを含む抗炎症性相乗的組み合わせ |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9901562B2 (ja) |
| EP (1) | EP2981256B1 (ja) |
| JP (2) | JP2016519101A (ja) |
| CN (1) | CN105407885B (ja) |
| AU (1) | AU2014246728B2 (ja) |
| ES (1) | ES2932248T3 (ja) |
| WO (1) | WO2014162313A1 (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9901562B2 (en) * | 2013-04-04 | 2018-02-27 | Lycored Ltd. | Anti-inflammatory omega-3 synergistic combinations |
| CN108354919A (zh) * | 2017-12-29 | 2018-08-03 | 广东海洋大学 | 一种用于提高抗氧化功能的不饱和脂肪酸组合物及其应用 |
| CN111053248A (zh) * | 2018-10-16 | 2020-04-24 | 东莞市维康医疗投资有限公司 | 一种地龙蛋白口服液及其制备方法 |
| US11357810B2 (en) | 2019-10-09 | 2022-06-14 | Brain Health Holding Llc | Compositions with purified Bombyx mori cocoon silk peptide fiber and refined Buglossoides arvensis seed oil having synergistic effects for improving memory, focus, and cognitive function, and related methods |
| US11707497B2 (en) | 2019-10-09 | 2023-07-25 | Brain Health Holding Llc | Methods and compositions with purified Bombyx mori cocoon silk peptide fiber and refined Buglossoides arvensis seed oil providing anti-inflammatory effects and neuroprotection for disease states |
| US20220387344A1 (en) * | 2019-10-10 | 2022-12-08 | Lycored Ltd. | Compositions and methods for inhibiting collagen loss |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5837311A (en) | 1993-12-13 | 1998-11-17 | Makhteshim Chemical Works Ltd. | Industrial processing of tomatoes and product thereof |
| ES2217495T3 (es) | 1998-02-13 | 2004-11-01 | Societe Des Produits Nestle S.A. | Tostada con guarnicion. |
| WO2001051088A1 (en) * | 2000-01-07 | 2001-07-19 | Anthony Cincotta | Composition for reducing plasma triglycerides, platelet aggregation, and oxidative capacity |
| EP1476143A1 (en) | 2002-02-15 | 2004-11-17 | DSM IP Assets B.V. | Compositions comprising lycopene for the treatment and prevention of angiogenesis associated pathologies |
| US20090326056A1 (en) | 2006-05-15 | 2009-12-31 | Regina Goralczyk | Novel actives against prostate carcinoma |
| KR20090109793A (ko) * | 2008-04-16 | 2009-10-21 | 홉킨스바이오연구센터(주) | 크랜베리 추출물 또는 복분자 추출물을 함유하는건강기능성식품 조성물 |
| CN102355894B (zh) | 2009-01-19 | 2016-06-15 | 利科雷德有限公司 | 类胡萝卜素和多酚的协同组合 |
| US20110008901A1 (en) | 2009-07-07 | 2011-01-13 | Kiernan Urban A | Apolipoprotein ciii in pre- and type 2 diabetes |
| BR112012010586A2 (pt) | 2009-11-06 | 2016-03-22 | Alcon Res Ltd | suplementos nutricionais para alívio de segura no olho. |
| EP2976070B1 (en) * | 2013-03-19 | 2021-05-12 | Lycored Ltd. | Anti-inflammatory synergistic combinations of astaxanthin with lycopene and carnosic acid |
| US9901562B2 (en) * | 2013-04-04 | 2018-02-27 | Lycored Ltd. | Anti-inflammatory omega-3 synergistic combinations |
-
2014
- 2014-03-04 US US14/782,583 patent/US9901562B2/en active Active
- 2014-04-03 ES ES14778751T patent/ES2932248T3/es active Active
- 2014-04-03 WO PCT/IL2014/050329 patent/WO2014162313A1/en active Application Filing
- 2014-04-03 CN CN201480024636.8A patent/CN105407885B/zh active Active
- 2014-04-03 AU AU2014246728A patent/AU2014246728B2/en active Active
- 2014-04-03 EP EP14778751.9A patent/EP2981256B1/en active Active
- 2014-04-03 JP JP2016505926A patent/JP2016519101A/ja active Pending
-
2017
- 2017-12-04 US US15/830,402 patent/US10154980B2/en active Active
-
2018
- 2018-11-30 JP JP2018224936A patent/JP6803898B2/ja active Active
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