JP2016515620A5 - - Google Patents
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- Publication number
- JP2016515620A5 JP2016515620A5 JP2016506353A JP2016506353A JP2016515620A5 JP 2016515620 A5 JP2016515620 A5 JP 2016515620A5 JP 2016506353 A JP2016506353 A JP 2016506353A JP 2016506353 A JP2016506353 A JP 2016506353A JP 2016515620 A5 JP2016515620 A5 JP 2016515620A5
- Authority
- JP
- Japan
- Prior art keywords
- xaa
- group
- lys
- ala
- phe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361807713P | 2013-04-02 | 2013-04-02 | |
| US61/807,713 | 2013-04-02 | ||
| US14/229,799 US20140294902A1 (en) | 2013-04-02 | 2014-03-28 | Novel a4b7 peptide antagonists |
| US14/229,799 | 2014-03-28 | ||
| PCT/US2014/032392 WO2014165449A1 (en) | 2013-04-02 | 2014-03-31 | NOVEL α4β7 PEPTIDE ANTAGONISTS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016515620A JP2016515620A (ja) | 2016-05-30 |
| JP2016515620A5 true JP2016515620A5 (https=) | 2017-05-18 |
Family
ID=51621090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016506353A Pending JP2016515620A (ja) | 2013-04-02 | 2014-03-31 | 新規のα４β７ペプチド拮抗薬 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20140294902A1 (https=) |
| EP (1) | EP2981543A4 (https=) |
| JP (1) | JP2016515620A (https=) |
| WO (1) | WO2014165449A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9273093B2 (en) | 2012-10-11 | 2016-03-01 | Protagonist Therapeutics, Inc. | α4β7 peptide dimer antagonists |
| EP4091624A1 (en) | 2013-03-15 | 2022-11-23 | Protagonist Therapeutics, Inc. | Hepcidin analogues and uses thereof |
| HRP20211448T1 (hr) | 2014-05-16 | 2021-12-24 | Protagonist Therapeutics, Inc. | Alfa4beta7 integrin tioeter peptidni antagonisti |
| CN107206254B (zh) | 2014-07-17 | 2021-08-24 | 领导医疗有限公司 | 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途 |
| US10301371B2 (en) | 2014-10-01 | 2019-05-28 | Protagonist Therapeutics, Inc. | Cyclic monomer and dimer peptides having integrin antagonist activity |
| WO2016054411A1 (en) | 2014-10-01 | 2016-04-07 | Protagonist Therapeutics, Inc. | NOVEL α4β7 PEPTIDE MONOMER AND DIMER ANTAGONISTS |
| US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| US20190002503A1 (en) | 2015-12-30 | 2019-01-03 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
| CA3017926C (en) | 2016-03-23 | 2023-10-10 | Protagonist Therapeutics, Inc. | Methods for synthesizing .alpha.4.beta.7 peptide antagonists |
| CN106366160B (zh) * | 2016-10-11 | 2019-06-14 | 厦门大学 | 基于二硫键精准配对构建富含二硫键多肽分子骨架的方法 |
| EP3681900A4 (en) | 2017-09-11 | 2021-09-08 | Protagonist Therapeutics, Inc. | OPIOID AGONIST PEPTIDES AND THEIR USES |
| CA3089868A1 (en) | 2018-02-08 | 2019-08-15 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| CN119285737A (zh) * | 2018-06-13 | 2025-01-10 | 雷沃生物治疗有限公司 | 具有消炎性质的新型蛋白质 |
| WO2020014646A1 (en) | 2018-07-12 | 2020-01-16 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| JP7534382B2 (ja) | 2019-07-10 | 2024-08-14 | プロタゴニスト セラピューティクス， インコーポレイテッド | インターロイキン－２３受容体のペプチド阻害剤及び炎症性疾患を治療するためのその使用 |
| AU2021209086A1 (en) | 2020-01-15 | 2022-08-04 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| CA3167751A1 (en) | 2020-01-15 | 2021-07-22 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| JP7397239B2 (ja) | 2020-11-20 | 2023-12-12 | ヤンセン ファーマシューティカ エヌ．ベー． | インターロイキン－２３受容体のペプチド阻害剤の組成物 |
| EP4370146A4 (en) | 2021-07-14 | 2025-05-21 | Janssen Biotech, Inc. | Lipidated peptide inhibitors of the interleukin-23 receptor |
| US20230145835A1 (en) * | 2021-10-06 | 2023-05-11 | 48Hd Biopharma Inc. | Modulators of Alpha-4-beta-7 Integrin and MAdCAM |
| CN116098884B (zh) * | 2022-12-12 | 2024-04-19 | 山东大学 | 一种n-乙酰-l-酪氨酸在制备治疗炎症性肠病药物中的应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU666853B2 (en) * | 1991-04-05 | 1996-02-29 | Genentech Inc. | Platelet aggregation inhibitors having high specificity for GP IIbIIIa |
| GB9613112D0 (en) * | 1996-06-21 | 1996-08-28 | Zeneca Ltd | Chemical compounds |
| JP2001509493A (ja) * | 1997-07-11 | 2001-07-24 | インナーダイン， インコーポレイテッド | 放射送達構造体の調製およびシール化のための方法およびシステム |
| US6248057B1 (en) * | 1998-07-28 | 2001-06-19 | Innerdyne, Inc. | Absorbable brachytherapy and chemotherapy delivery devices and methods |
| WO2001068586A2 (en) * | 2000-03-14 | 2001-09-20 | Novartis Ag | α4β1 AND α4β7 INTEGRIN INHIBITORS |
| KR100983997B1 (ko) * | 2001-01-09 | 2010-09-28 | 메르크 파텐트 게엠베하 | 수용체 타이로신 키나아제 저해제 및 혈관형성 저해제를 사용하는 병용 요법 |
| DE10107707A1 (de) * | 2001-02-19 | 2002-08-29 | Wilex Biotechnology Gmbh | Antagonisten für alpha¶4¶beta¶7¶-Integrin |
| GB0610395D0 (en) * | 2006-05-25 | 2006-07-05 | Ge Healthcare Ltd | Novel imaging agents |
| US9193790B2 (en) * | 2006-12-07 | 2015-11-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of antagonists of the interaction between HIV GP120 and A4B7 integrin |
| CA2787331A1 (en) * | 2010-01-25 | 2011-07-28 | Hazel H. Szeto | Aromatic-cationic peptides and uses of same |
| JP2011231085A (ja) * | 2010-04-30 | 2011-11-17 | Osaka Prefecture Univ | 環状ペプチド |
| EP2444101A1 (en) * | 2010-10-21 | 2012-04-25 | Universitätsklinikum Freiburg | Selective targeting of the CD40L/Mac-1 interaction by small peptide inhibitors and its use for the treatment of inflammation and atherogenesis |
-
2014
- 2014-03-28 US US14/229,799 patent/US20140294902A1/en not_active Abandoned
- 2014-03-31 EP EP14780207.8A patent/EP2981543A4/en not_active Withdrawn
- 2014-03-31 WO PCT/US2014/032392 patent/WO2014165449A1/en not_active Ceased
- 2014-03-31 JP JP2016506353A patent/JP2016515620A/ja active Pending
-
2019
- 2019-02-22 US US16/282,920 patent/US20200017549A1/en not_active Abandoned
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