JP2016510766A5 - - Google Patents
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- Publication number
- JP2016510766A5 JP2016510766A5 JP2015561751A JP2015561751A JP2016510766A5 JP 2016510766 A5 JP2016510766 A5 JP 2016510766A5 JP 2015561751 A JP2015561751 A JP 2015561751A JP 2015561751 A JP2015561751 A JP 2015561751A JP 2016510766 A5 JP2016510766 A5 JP 2016510766A5
- Authority
- JP
- Japan
- Prior art keywords
- immunoglobulin
- cells
- progenitor cells
- composition
- stem cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000000130 stem cell Anatomy 0.000 claims 28
- 229920001184 polypeptide Polymers 0.000 claims 10
- 210000001185 bone marrow Anatomy 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 206010012601 diabetes mellitus Diseases 0.000 claims 4
- 108060003951 Immunoglobulin Proteins 0.000 claims 3
- 230000003511 endothelial effect Effects 0.000 claims 3
- 102000018358 immunoglobulin Human genes 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 102100035902 Glutamate decarboxylase 1 Human genes 0.000 claims 2
- 102100035857 Glutamate decarboxylase 2 Human genes 0.000 claims 2
- 101000873546 Homo sapiens Glutamate decarboxylase 1 Proteins 0.000 claims 2
- 101000873786 Homo sapiens Glutamate decarboxylase 2 Proteins 0.000 claims 2
- 210000001744 T-lymphocyte Anatomy 0.000 claims 2
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 2
- 230000000735 allogeneic effect Effects 0.000 claims 2
- 210000003719 b-lymphocyte Anatomy 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 1
- 210000000496 pancreas Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361775115P | 2013-03-08 | 2013-03-08 | |
| US61/775,115 | 2013-03-08 | ||
| PCT/US2014/022321 WO2014138725A1 (en) | 2013-03-08 | 2014-03-10 | Methods and compositions for the treatment and/or prevention of type 1 diabetes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016510766A JP2016510766A (ja) | 2016-04-11 |
| JP2016510766A5 true JP2016510766A5 (https=) | 2017-04-06 |
Family
ID=51492039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015561751A Pending JP2016510766A (ja) | 2013-03-08 | 2014-03-10 | １型糖尿病の処置及び／又は予防のための方法及び組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11338036B2 (https=) |
| EP (1) | EP2964750B1 (https=) |
| JP (1) | JP2016510766A (https=) |
| CN (1) | CN105358678A (https=) |
| AU (1) | AU2014225307A1 (https=) |
| CA (1) | CA2904586A1 (https=) |
| WO (1) | WO2014138725A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2018124307A (ru) * | 2015-12-04 | 2020-01-14 | Новартис Аг | Антительно-цитокиновые привитые композиции и способы применения для иммунорегуляции |
| US20200030377A1 (en) * | 2016-09-23 | 2020-01-30 | The Curators Of The University Of Missouri | Antigen-specific immune modulation |
| JP2018141728A (ja) * | 2017-02-28 | 2018-09-13 | トヨタ自動車株式会社 | 生活習慣病の診断方法 |
| MY206158A (en) | 2017-05-24 | 2024-12-02 | Novartis Ag | Antibody-cytokine engrafted proteins and methods of use in the treatment of cancer |
| JOP20190271A1 (ar) | 2017-05-24 | 2019-11-21 | Novartis Ag | بروتينات مطعّمة بسيتوكين- الجسم المضاد وطرق الاستخدام للاضطرابات المتعلقة بالمناعة |
| CN112839707A (zh) * | 2019-05-14 | 2021-05-25 | 普瑞文森生物有限公司 | 用于预防i型糖尿病的方法和组合物 |
| JP2024520444A (ja) | 2021-05-24 | 2024-05-24 | プロヴェンション・バイオ・インコーポレイテッド | １型糖尿病を治療するための方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4486188A (en) | 1980-08-14 | 1984-12-04 | Applied Medical Devices, Inc. | Bone marrow transplant method and apparatus |
| US4481946A (en) | 1980-08-14 | 1984-11-13 | Altshuler John H | Bone marrow transplant method and apparatus |
| US5470582A (en) | 1992-02-07 | 1995-11-28 | Syntex (U.S.A.) Inc. | Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles |
| US6372716B1 (en) | 1994-04-26 | 2002-04-16 | Genetics Institute, Inc. | Formulations for factor IX |
| US6685940B2 (en) | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
| US6566329B1 (en) | 1999-06-28 | 2003-05-20 | Novo Nordisk A/S | Freeze-dried preparation of human growth hormone |
| US8609091B2 (en) | 2002-04-09 | 2013-12-17 | The Curators Of The University Of Missouri | Method for endocytic presentation of an immunosuppressive for the treatment of type 1 diabetes |
| US8603472B2 (en) * | 2002-04-09 | 2013-12-10 | The Curators Of The University Of Missouri | Methods and compositions reversing pre-diabetes using fusion proteins comprising a GAD peptide |
| US7744876B2 (en) * | 2002-04-09 | 2010-06-29 | The Curators Of The University Of Missouri | Methods and compositions for treatment, prevention, suppression, and/or delaying the onset of type 1 diabetes |
| US8603471B2 (en) * | 2002-04-09 | 2013-12-10 | The Curators Of The University Of Missouri | Methods and compositions for preventing the onset of type 1 diabetes |
| EP1668119A2 (en) * | 2003-09-15 | 2006-06-14 | Ramot at Tel Aviv University Ltd. | Insulin-producing bone marrow derived cells and methods of generating and using same |
| DE602004021847D1 (de) | 2003-11-27 | 2009-08-13 | Develogen Ag | Verfahren zur prävention und behandlung von diabetes mit neurturin |
| US20120058105A1 (en) | 2008-06-27 | 2012-03-08 | Martin Kean Chong Ng | Method of treatment of vascular complications |
-
2014
- 2014-03-10 CN CN201480022386.4A patent/CN105358678A/zh active Pending
- 2014-03-10 WO PCT/US2014/022321 patent/WO2014138725A1/en not_active Ceased
- 2014-03-10 EP EP14760521.6A patent/EP2964750B1/en active Active
- 2014-03-10 CA CA2904586A patent/CA2904586A1/en not_active Abandoned
- 2014-03-10 JP JP2015561751A patent/JP2016510766A/ja active Pending
- 2014-03-10 AU AU2014225307A patent/AU2014225307A1/en not_active Abandoned
- 2014-03-10 US US14/773,497 patent/US11338036B2/en active Active
-
2021
- 2021-09-03 US US17/466,097 patent/US20220008535A1/en not_active Abandoned
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