JP2016508501A5 - - Google Patents
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- JP2016508501A5 JP2016508501A5 JP2015556127A JP2015556127A JP2016508501A5 JP 2016508501 A5 JP2016508501 A5 JP 2016508501A5 JP 2015556127 A JP2015556127 A JP 2015556127A JP 2015556127 A JP2015556127 A JP 2015556127A JP 2016508501 A5 JP2016508501 A5 JP 2016508501A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- red blood
- subject
- use according
- blood cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 46
- 210000003743 erythrocyte Anatomy 0.000 claims 40
- 238000000034 method Methods 0.000 claims 23
- 210000004369 blood Anatomy 0.000 claims 18
- 239000008280 blood Substances 0.000 claims 18
- 230000002708 enhancing effect Effects 0.000 claims 11
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 claims 9
- 229930024421 Adenine Natural products 0.000 claims 9
- UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 claims 9
- 229930010555 Inosine Natural products 0.000 claims 9
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 claims 9
- 229960000643 adenine Drugs 0.000 claims 9
- 229960003786 inosine Drugs 0.000 claims 9
- XOHUEYCVLUUEJJ-UHFFFAOYSA-N 2,3-Bisphosphoglyceric acid Chemical compound OP(=O)(O)OC(C(=O)O)COP(O)(O)=O XOHUEYCVLUUEJJ-UHFFFAOYSA-N 0.000 claims 8
- 238000002405 diagnostic procedure Methods 0.000 claims 7
- 229910000162 sodium phosphate Inorganic materials 0.000 claims 6
- 239000001488 sodium phosphate Substances 0.000 claims 6
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 4
- 229910019142 PO4 Inorganic materials 0.000 claims 3
- 239000012530 fluid Substances 0.000 claims 3
- 238000011534 incubation Methods 0.000 claims 3
- 239000010452 phosphate Substances 0.000 claims 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 3
- 239000002244 precipitate Substances 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- 230000000287 tissue oxygenation Effects 0.000 claims 3
- 238000005406 washing Methods 0.000 claims 3
- 206010046274 Upper gastrointestinal haemorrhage Diseases 0.000 claims 2
- 238000010924 continuous production Methods 0.000 claims 2
- 230000003247 decreasing effect Effects 0.000 claims 2
- 208000028867 ischemia Diseases 0.000 claims 2
- 229940076788 pyruvate Drugs 0.000 claims 2
- 238000001356 surgical procedure Methods 0.000 claims 2
- 206010040047 Sepsis Diseases 0.000 claims 1
- 206010040070 Septic Shock Diseases 0.000 claims 1
- 208000006011 Stroke Diseases 0.000 claims 1
- 208000007502 anemia Diseases 0.000 claims 1
- 239000006285 cell suspension Substances 0.000 claims 1
- 238000007865 diluting Methods 0.000 claims 1
- 239000011521 glass Substances 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 210000000265 leukocyte Anatomy 0.000 claims 1
- 230000007102 metabolic function Effects 0.000 claims 1
- 208000010125 myocardial infarction Diseases 0.000 claims 1
- 238000006213 oxygenation reaction Methods 0.000 claims 1
- 230000003389 potentiating effect Effects 0.000 claims 1
- 238000009597 pregnancy test Methods 0.000 claims 1
- 230000003716 rejuvenation Effects 0.000 claims 1
- 230000036303 septic shock Effects 0.000 claims 1
- 229960003339 sodium phosphate Drugs 0.000 claims 1
- 238000003860 storage Methods 0.000 claims 1
- 239000006228 supernatant Substances 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/756,116 | 2013-01-31 | ||
| US13/756,116 US9102918B2 (en) | 2013-01-31 | 2013-01-31 | Methods for rejuvenating red blood cells |
| US13/844,773 US9103842B2 (en) | 2013-01-31 | 2013-03-15 | Methods for rejuvenating red blood cells |
| US13/844,773 | 2013-03-15 | ||
| PCT/US2014/013845 WO2014120919A1 (en) | 2013-01-31 | 2014-01-30 | Methods for rejuvenating red blood cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016508501A JP2016508501A (ja) | 2016-03-22 |
| JP2016508501A5 true JP2016508501A5 (https=) | 2017-03-16 |
Family
ID=50193576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015556127A Pending JP2016508501A (ja) | 2013-01-31 | 2014-01-30 | 赤血球を回復させるための方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US9103842B2 (https=) |
| EP (1) | EP2950802A1 (https=) |
| JP (1) | JP2016508501A (https=) |
| WO (1) | WO2014120919A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9066909B2 (en) | 2012-09-06 | 2015-06-30 | Biomet Biologics, Llc | Methods for producing and using rejuvenated red blood cells |
| US10253295B2 (en) * | 2012-09-06 | 2019-04-09 | Biomet Manufacturing, Llc | Methods for producing rejuvenated red blood cells |
| US9102918B2 (en) | 2013-01-31 | 2015-08-11 | Biomet Biologics, Llc | Methods for rejuvenating red blood cells |
| US9011408B2 (en) | 2013-01-31 | 2015-04-21 | Biomet Biologics, Llc | Functionally-closed, sterile blood processing solution system and method |
| US9103842B2 (en) | 2013-01-31 | 2015-08-11 | Biomet Biologics, Llc | Methods for rejuvenating red blood cells |
| US9920313B2 (en) | 2013-10-21 | 2018-03-20 | Biomet Biologics, Llc | Cell washing device using a wave |
| FR3069323B1 (fr) | 2017-07-20 | 2023-10-20 | Lsee | Bandelettes electrochimiques permettant le suivi de la degradation des graisses de l'organisme et leur procede de preparation |
| EP4096687A4 (en) * | 2020-01-28 | 2024-02-28 | Orgenesis Inc. | Process and system for acellular therapy |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3874384A (en) | 1971-11-01 | 1975-04-01 | American Hospital Supply Corp | Improved blood storage unit and method of storing blood |
| US4004586A (en) | 1975-03-12 | 1977-01-25 | Baxter Travenol Laboratories, Inc. | Method and apparatus for sealed, sterile connection |
| US4116646A (en) | 1977-05-20 | 1978-09-26 | Millipore Corporation | Filter unit |
| JPS62501890A (ja) | 1985-02-26 | 1987-07-30 | バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテッド | 流体移換システム |
| US4994039A (en) | 1985-11-15 | 1991-02-19 | Mattson Philip D | Apparatus and method for patients from a single donor or a restricted group of donors |
| US5098371A (en) | 1987-10-24 | 1992-03-24 | Kawasumi Laboratories, Inc. | Switch bag type blood gathering set |
| JP3008354B2 (ja) * | 1988-09-27 | 2000-02-14 | 科学技術振興事業団 | 体外血液循環装置に使用する血液添加組成物 |
| CA2067134C (en) | 1989-10-06 | 2001-02-13 | Harold T. Meryman | Procedure for storing red cells with prolonged maintenance of cellular concentrations of atp and 2,3 dpg |
| US20010037978A1 (en) | 1999-04-20 | 2001-11-08 | Daryl R. Calhoun | Filter assembly having a flexible housing and method of making same |
| US7169547B2 (en) | 1994-12-05 | 2007-01-30 | New York Blood Center, Inc. | High concentration white blood cells as a therapeutic product |
| US6190855B1 (en) | 1996-10-28 | 2001-02-20 | Baxter International Inc. | Systems and methods for removing viral agents from blood |
| CA2278208C (en) | 1997-01-24 | 2011-09-20 | Asahi Medical Co., Ltd. | Cell separation method |
| US6059968A (en) | 1998-01-20 | 2000-05-09 | Baxter International Inc. | Systems for processing and storing placenta/umbilical cord blood |
| US6267745B1 (en) | 1998-05-21 | 2001-07-31 | Baxter International Inc. | Confined air tube and methods for handling air in closed blood processing systems |
| US6358420B2 (en) | 1998-06-01 | 2002-03-19 | Baxter International Inc. | Blood collection method employing an air venting blood sample tube |
| JP3517359B2 (ja) | 1998-09-14 | 2004-04-12 | テルモ株式会社 | 細胞分離・回収装置および細胞の分離・回収方法 |
| JP2003507430A (ja) | 1999-08-25 | 2003-02-25 | ジーエムピー カンパニーズ，インコーポレーテッド | 哺乳動物中で酸素運搬を向上する薬剤 |
| JP2002173433A (ja) | 2000-12-04 | 2002-06-21 | Terumo Corp | 白血球除去血液製剤の調製方法および血液セット |
| CA2467223A1 (en) | 2001-11-16 | 2003-05-30 | Hollinger Digital, Inc. | Method for extending the useful shelf-life of refrigerated red blood cells by nutrient supplementation |
| CA2467087A1 (en) | 2001-11-16 | 2003-05-30 | Hemanext, Llc | Additive solution for blood preservation |
| US20060180526A1 (en) | 2003-03-20 | 2006-08-17 | Terumo Kabushiki Kaisha | Blood treating set and cell treating set |
| EP1671664B1 (en) | 2003-10-02 | 2017-05-03 | Terumo Kabushiki Kaisha | Method of producing blood processing circuits and filter unit |
| US20050074743A1 (en) | 2003-10-06 | 2005-04-07 | Purmal Andrei A. | Method and composition for treating a biological sample |
| US20110139276A1 (en) | 2004-11-17 | 2011-06-16 | Noble House Group Pty Ltd. | Sterile sampling methods and apparatus |
| US9314014B2 (en) | 2004-02-18 | 2016-04-19 | University Of Maryland, Baltimore | Compositions and methods for the storage of red blood cells |
| DE102004035352B4 (de) | 2004-07-21 | 2007-05-10 | Gerätezentrale für Bluttransfusion des Österreichischen Roten Kreuzes GmbH | Geschlossenes steriles System zum Filtrieren von biologischen oder medizinischen Flüssigkeiten, insbesondere von Vollblut |
| JPWO2006016421A1 (ja) | 2004-08-12 | 2008-05-01 | 株式会社ジェイ・エム・エス | 濾過装置及び濾過方法 |
| WO2007018999A1 (en) | 2005-08-05 | 2007-02-15 | Pall Corporation | Apparatus and system for displacing gas in a biological fluid processing system |
| US8448786B2 (en) | 2009-06-30 | 2013-05-28 | Medline Industries, Inc. | Catheter tray, packaging system, instruction insert, and associated methods |
| US9199016B2 (en) | 2009-10-12 | 2015-12-01 | New Health Sciences, Inc. | System for extended storage of red blood cells and methods of use |
| CN106135195A (zh) | 2010-02-16 | 2016-11-23 | 维亚塞尔有限责任公司 | 含有精氨酸的组合物和用于处理红细胞的方法 |
| WO2012006204A2 (en) | 2010-07-06 | 2012-01-12 | Cytonet, Llp | Devices and methods for processing a biomaterial in a closed system |
| CA2826969C (en) | 2010-11-29 | 2019-02-19 | New York Blood Center, Inc. | Method of blood pooling and storage |
| US9066909B2 (en) | 2012-09-06 | 2015-06-30 | Biomet Biologics, Llc | Methods for producing and using rejuvenated red blood cells |
| WO2014039660A1 (en) | 2012-09-06 | 2014-03-13 | Biomet Biologics, Llc | Methods for producing rejuvenated red blood cells |
| US9011408B2 (en) | 2013-01-31 | 2015-04-21 | Biomet Biologics, Llc | Functionally-closed, sterile blood processing solution system and method |
| US9102918B2 (en) | 2013-01-31 | 2015-08-11 | Biomet Biologics, Llc | Methods for rejuvenating red blood cells |
| US9103842B2 (en) | 2013-01-31 | 2015-08-11 | Biomet Biologics, Llc | Methods for rejuvenating red blood cells |
-
2013
- 2013-03-15 US US13/844,773 patent/US9103842B2/en active Active
-
2014
- 2014-01-30 EP EP14707864.6A patent/EP2950802A1/en not_active Withdrawn
- 2014-01-30 WO PCT/US2014/013845 patent/WO2014120919A1/en not_active Ceased
- 2014-01-30 JP JP2015556127A patent/JP2016508501A/ja active Pending
-
2015
- 2015-06-24 US US14/748,649 patent/US9808487B2/en active Active
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