JP2016505065A - 心血管症候の治療方法 - Google Patents

心血管症候の治療方法 Download PDF

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Publication number
JP2016505065A
JP2016505065A JP2015554265A JP2015554265A JP2016505065A JP 2016505065 A JP2016505065 A JP 2016505065A JP 2015554265 A JP2015554265 A JP 2015554265A JP 2015554265 A JP2015554265 A JP 2015554265A JP 2016505065 A JP2016505065 A JP 2016505065A
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JP
Japan
Prior art keywords
hours
patient
natriuretic peptide
peptide
urodilatin
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Pending
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JP2015554265A
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English (en)
Japanese (ja)
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JP2016505065A5 (enExample
Inventor
ホルツマイスター,ヨハネス
Original Assignee
カーディオレンティス リミテッド
カーディオレンティス リミテッド
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Application filed by カーディオレンティス リミテッド, カーディオレンティス リミテッド filed Critical カーディオレンティス リミテッド
Publication of JP2016505065A publication Critical patent/JP2016505065A/ja
Publication of JP2016505065A5 publication Critical patent/JP2016505065A5/ja
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2242Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2221Relaxins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Dermatology (AREA)
JP2015554265A 2013-01-25 2014-01-24 心血管症候の治療方法 Pending JP2016505065A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361756692P 2013-01-25 2013-01-25
US61/756,692 2013-01-25
PCT/IB2014/000253 WO2014115033A2 (en) 2013-01-25 2014-01-24 Methods of treating cardiovascular indications

Publications (2)

Publication Number Publication Date
JP2016505065A true JP2016505065A (ja) 2016-02-18
JP2016505065A5 JP2016505065A5 (enExample) 2016-12-01

Family

ID=50382492

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015554265A Pending JP2016505065A (ja) 2013-01-25 2014-01-24 心血管症候の治療方法

Country Status (19)

Country Link
US (2) US20140213520A1 (enExample)
EP (1) EP2948165A2 (enExample)
JP (1) JP2016505065A (enExample)
KR (1) KR20150108903A (enExample)
CN (1) CN105025918A (enExample)
AP (1) AP2015008624A0 (enExample)
AU (1) AU2014208851B2 (enExample)
BR (1) BR112015017432A2 (enExample)
CA (1) CA2898571A1 (enExample)
DO (1) DOP2015000175A (enExample)
EA (1) EA201500765A1 (enExample)
IL (1) IL239909A0 (enExample)
MX (1) MX2015009606A (enExample)
NZ (1) NZ710246A (enExample)
PH (1) PH12015501559A1 (enExample)
SG (1) SG11201505492XA (enExample)
TN (1) TN2015000315A1 (enExample)
TW (1) TW201442722A (enExample)
WO (1) WO2014115033A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015184248A1 (en) * 2014-05-30 2015-12-03 Concert Pharmaceuticals, Inc. Methods of treating fibrotic diseases
CN105617360B (zh) * 2015-12-04 2018-12-21 中国农业大学 C-型钠肽在制备外用避孕药和精子功能检测试剂中的应用
AU2017368050A1 (en) 2016-11-29 2019-06-20 Puretech Lyt, Inc. Exosomes for delivery of therapeutic agents
CN110278941B (zh) * 2019-07-11 2021-05-28 西安国际医学中心有限公司 一种含有钠尿肽的离体心脏保护液

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010116325A (ja) * 2008-11-11 2010-05-27 Institute For Protein Science Co Ltd Sirs患者を救命するためのペプチド組成物
JP2011520917A (ja) * 2008-05-16 2011-07-21 コーセラ,インコーポレーテッド 慢性心不全の治療方法

Family Cites Families (20)

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DE3346953A1 (de) 1983-12-24 1985-08-14 Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft mbH, 6900 Heidelberg Cardiodilatin, ein neues peptidhormon und verfahren zu seiner herstellung
US5449751A (en) 1987-03-02 1995-09-12 Pharma Bissendorf Peptide Gmbh Cardiodilatin fragment, process for preparing same and use thereof
US5461142A (en) 1987-11-07 1995-10-24 Pharma Bissendorf Peptide Gmbh Phosphorylated derivatives of cardiodilatin/ANF peptides
US5166191A (en) * 1991-08-19 1992-11-24 Genentech, Inc. Use of relaxin in cardiovascular therapy
DE4216133A1 (de) 1992-05-15 1993-11-18 Bissendorf Peptide Gmbh Anwendung von Urodilatin bei Lungen- und Bronchialerkrankungen
ES2188665T3 (es) 1994-06-02 2003-07-01 Forssmann Wolf Georg Procedimiento para la preparacion de fragmentos de cardiodilatina, fragmentos de cardiodilatina muy purificados y productos intermedios para su preparacion.
DE19951471A1 (de) 1999-10-26 2001-05-03 Forssmann Wolf Georg Verwendung von Urodilatin zur Behandlung chronischer Niereninsuffizienz mit Nierenrestfunktionen
US6407211B1 (en) * 1999-12-17 2002-06-18 Mayo Foundation For Medical Education And Research Chimeric natriuretic peptides
NZ525389A (en) * 2000-10-04 2009-04-30 Molecular Medicine Res Inst Methods of modulating apoptosis by administration of relaxin agonists or antagonists
KR101271635B1 (ko) * 2001-12-21 2013-06-12 휴먼 게놈 사이언시즈, 인코포레이티드 알부민 융합 단백질
US20050113286A1 (en) * 2002-03-18 2005-05-26 Schreiner George F. Methods for treating congestive heart failure
WO2006110743A1 (en) * 2005-04-07 2006-10-19 Cardiopep Pharma Gmbh Use of natriuretic peptide for treating heart failure
US8293711B2 (en) * 2007-09-11 2012-10-23 Pharis Biotech Gmbh Use of natriuretic peptides for treating angioedema syndromes
WO2009086126A2 (en) * 2007-12-21 2009-07-09 Mayo Foundation For Medical Education And Research Natriuretic polypeptides
WO2010048308A2 (en) * 2008-10-24 2010-04-29 Deborah Dickey Natriuretic polypeptides
US20110014180A1 (en) * 2009-07-16 2011-01-20 Masafumi Koide Preparations for tissue restoration containing atrial diuretic hormone and family molecules as active ingredients; method of restoring tissue using the preparation; agents for growing, restoring, promoting growth of hair and agents for promoting restoration of skin tissue and cardiac muscle tissue containing atrial diuretic hormone family molecules as active ingredients; method of growing, restoring, promoting growth of hair by using the agents; and method of promoting restoration of skin tissue and cardiac muscle tissue
UY32902A (es) * 2009-09-25 2011-02-28 Alcon Res Ltd Nuevos agonistas de npr-b
US8551938B2 (en) * 2009-09-25 2013-10-08 Alcon Research, Ltd. NPR-B agonists
US20130197188A1 (en) * 2010-03-15 2013-08-01 Wolf-Georg Forssmann Use of urodilatin for preparing a medicament for the treatment of cardiovascular, renal, pulmonary and neuronal syndromes while avoiding a rebound
US20120052097A1 (en) * 2010-08-20 2012-03-01 Cerulean Pharma Inc. Therapeutic peptide-polymer conjugates, particles, compositions, and related methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011520917A (ja) * 2008-05-16 2011-07-21 コーセラ,インコーポレーテッド 慢性心不全の治療方法
JP2010116325A (ja) * 2008-11-11 2010-05-27 Institute For Protein Science Co Ltd Sirs患者を救命するためのペプチド組成物

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AM HEART J, 2005, VOL.150, 1239.E1-1239.E8, JPN6017027281, ISSN: 0003748281 *
AMERICAN HEART JOURNAL, 1995, VOL.129, 766-73, JPN6017027290, ISSN: 0003748283 *
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, VOL.48, NO.12, 2397-409, JPN6017027287, ISSN: 0003748282 *

Also Published As

Publication number Publication date
NZ710246A (en) 2016-11-25
WO2014115033A3 (en) 2015-02-26
WO2014115033A2 (en) 2014-07-31
AU2014208851B2 (en) 2016-12-22
CA2898571A1 (en) 2014-07-31
MX2015009606A (es) 2016-04-26
DOP2015000175A (es) 2015-11-15
KR20150108903A (ko) 2015-09-30
US20140213520A1 (en) 2014-07-31
AU2014208851A1 (en) 2015-08-06
BR112015017432A2 (pt) 2017-07-11
EA201500765A1 (ru) 2015-12-30
SG11201505492XA (en) 2015-08-28
US20140213519A1 (en) 2014-07-31
TN2015000315A1 (en) 2017-01-03
CN105025918A (zh) 2015-11-04
TW201442722A (zh) 2014-11-16
PH12015501559A1 (en) 2015-09-21
AP2015008624A0 (en) 2015-07-31
IL239909A0 (en) 2015-08-31
EP2948165A2 (en) 2015-12-02

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