JP2016505006A - レボノルゲストレル及びエチニルエストラジオール用の経皮薬物送達システム - Google Patents

レボノルゲストレル及びエチニルエストラジオール用の経皮薬物送達システム Download PDF

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JP2016505006A
JP2016505006A JP2015550784A JP2015550784A JP2016505006A JP 2016505006 A JP2016505006 A JP 2016505006A JP 2015550784 A JP2015550784 A JP 2015550784A JP 2015550784 A JP2015550784 A JP 2015550784A JP 2016505006 A JP2016505006 A JP 2016505006A
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levonorgestrel
drug delivery
delivery system
transdermal drug
ethinyl estradiol
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JP2015550784A
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Japanese (ja)
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JP2016505006A5 (https=
Inventor
プラシャント パテル
プラシャント パテル
ヴィエト グエン
ヴィエト グエン
ジュン リャオ
ジュン リャオ
Original Assignee
ノーヴェン ファーマシューティカルズ インコーポレイテッド
ノーヴェン ファーマシューティカルズ インコーポレイテッド
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Publication of JP2016505006A publication Critical patent/JP2016505006A/ja
Publication of JP2016505006A5 publication Critical patent/JP2016505006A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2015550784A 2012-12-28 2013-12-27 レボノルゲストレル及びエチニルエストラジオール用の経皮薬物送達システム Pending JP2016505006A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261747013P 2012-12-28 2012-12-28
US61/747,013 2012-12-28
PCT/US2013/077932 WO2014106014A1 (en) 2012-12-28 2013-12-27 Transdermal drug delivery systems for levonorgestrel and ethinyl estradiol

Publications (2)

Publication Number Publication Date
JP2016505006A true JP2016505006A (ja) 2016-02-18
JP2016505006A5 JP2016505006A5 (https=) 2017-02-09

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JP2015550784A Pending JP2016505006A (ja) 2012-12-28 2013-12-27 レボノルゲストレル及びエチニルエストラジオール用の経皮薬物送達システム

Country Status (5)

Country Link
US (2) US9314470B2 (https=)
JP (1) JP2016505006A (https=)
AR (1) AR094289A1 (https=)
TW (1) TW201431554A (https=)
WO (1) WO2014106014A1 (https=)

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US9314470B2 (en) 2012-12-28 2016-04-19 Noven Pharmaceuticals, Inc. Transdermal drug delivery systems for levonorgestrel and ethinyl estradiol
MX366230B (es) 2012-12-28 2019-07-03 Noven Pharma Composiciones multipolimericas para liberación transdermica de farmaco.
WO2014159582A1 (en) 2013-03-14 2014-10-02 Noven Pharmaceuticals, Inc Amphetamine transdermal compositions with acrylic block copolymer
AR095259A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria
AR095260A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones de anfetaminas transdérmicas estables y métodos de fabricación
AU2016215180B2 (en) 2015-02-06 2020-01-02 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
US10406116B2 (en) 2015-02-06 2019-09-10 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
US20170000745A1 (en) * 2015-07-02 2017-01-05 Noven Pharmaceuticals, Inc. Transdermal drug delivery systems for levonorgestrel and ethinyl estradiol
JP7220473B2 (ja) * 2017-10-30 2023-02-10 帝國製薬株式会社 経皮投与製剤

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JPH01165529A (ja) * 1987-11-23 1989-06-29 Alza Corp 皮膚透過促進剤としてグリセロールモノオレエートを用いる治療系
JP2003533434A (ja) * 1999-11-24 2003-11-11 アジル・セラピユーテイクス・インコーポレーテツド 改良された経皮的避妊薬送達系および方法
JP2007217328A (ja) * 2006-02-16 2007-08-30 Hisamitsu Pharmaceut Co Inc 経皮吸収製剤
WO2011118683A1 (ja) * 2010-03-25 2011-09-29 東洋化学株式会社 医用貼付剤
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Title
寺原孝明: "９ 全身作用発現を期待した薬物の経皮吸収製剤の開発と応用", 難吸収性薬物の吸収性改善と新規投与製剤の開発, vol. 第１刷, JPN6018008940, 2012, pages 257 - 264, ISSN: 0003756486 *

Also Published As

Publication number Publication date
WO2014106014A1 (en) 2014-07-03
US20160296535A1 (en) 2016-10-13
AR094289A1 (es) 2015-07-22
US10231977B2 (en) 2019-03-19
US20140182597A1 (en) 2014-07-03
TW201431554A (zh) 2014-08-16
US9314470B2 (en) 2016-04-19

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