JP2016503811A - 脂肪酸および非イオン性直鎖ポリマーを含む日焼け止め剤組成物 - Google Patents
脂肪酸および非イオン性直鎖ポリマーを含む日焼け止め剤組成物 Download PDFInfo
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- JP2016503811A JP2016503811A JP2015550018A JP2015550018A JP2016503811A JP 2016503811 A JP2016503811 A JP 2016503811A JP 2015550018 A JP2015550018 A JP 2015550018A JP 2015550018 A JP2015550018 A JP 2015550018A JP 2016503811 A JP2016503811 A JP 2016503811A
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- 229940011671 vitamin b6 Drugs 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
- 230000037373 wrinkle formation Effects 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
- 229910000368 zinc sulfate Inorganic materials 0.000 description 1
- 229960001763 zinc sulfate Drugs 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8129—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers or esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers, e.g. polyvinylmethylether
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/90—Block copolymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
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Abstract
Description
(i)0.1から5%のUVA日焼け止め剤;
(ii)0.1から10%のUVB日焼け止め剤;
(iii)0.1から10%の、ポリビニルアルコール、修飾セルロースおよびポリ(プロピレンオキシド−co−エチレンオキシド)より選択される、8000より高い分子量および7から18のHLB値を有する非イオン性直鎖ポリマー;
(iv)4から25%の脂肪酸;ならびに
(v)40から80%の水
を含む、最大12%の有機日焼け止め剤を含む日焼け止め剤組成物が提供される。
10未満の値:脂溶性(非水溶性)
10を超える値:水溶性
4から8の値は、消泡剤を示す。
ヒストリック酸:45%パルミチン酸および55%ステアリン酸の混合物である。
IPM:イソプロピルミリステート
パルソールMCX:DSMが供給する化学名2−エチルヘキシル−4−メトキシシンナメートのUV−B日焼け止め剤。
HEC:ヒドロキシエチルセルロース
SCMC:ナトリウムカルボキシメチルセルロース
MC:メチルセルロース
PVA1:86.5−89%DHを有し、(20℃における4%溶液が)4.8から5.8cPの粘度を有する、ゴーセノールによるカタログ番号LH−05のポリビニルアルコールである。
インビトロSPF測定のために、処方物2mg/cm2を、70mm粗面化PMMAプレート−6μm粗さ(シェーンベルクGmbH&Co.KG)上に一定の間隔で適用速度2mg/cm2にて30秒以内に小さい点状に適用した。これらの点を、指サックとしてパラフィルムを使用して、系統的な方法で均一に塗り広げて、基材を処方物と共に15分間乾燥させた。SPF値は、オプトメトリックスSPF 290Sシステムを使用して測定した。
各種の種類のポリビニルアルコールを使用して、表3に示すような、異なる種類のこのようなポリマーの本発明の組成物に対する効果を調べた。表3の組成物のSPFを先に記載したのと同じ手順を使用して測定し、データも表3にまとめる。
PVA1:86.5−89%DHを有し、(20℃における4%溶液が)4.8から5.8cPの粘度を有する、ゴーセノールによるカタログ番号LH−05のポリビニルアルコールである。
PVA1:86.5−89%DHを有し、(20℃における4%溶液が)4.8から5.8cPの粘度を有する、ゴーセノールによるカタログ番号LH−05のポリビニルアルコールPVA1を、PVAの量を表4に示すように変化させたことを除いて、実施例3と同様に組成物中で使用して、先に記載した手順を使用してこれらの組成物のSPFを測定した。
脂肪酸(ヒストリック酸)の量を変化させたことを除いて、実施例9と同様の各種の組成物を以下の表5に示すように調製した。使用した脂肪酸の量のSPFの効果を以下に示す。
Claims (13)
- 日焼け止め剤組成物であって、
(i)0.1から5%のUVA日焼け止め剤;
(ii)0.1から10%のUVB日焼け止め剤;
(iii)0.1から10%の、ポリビニルアルコール、修飾セルロースおよびポリ(プロピレンオキシド−co−エチレンオキシド)より選択される、8000より高い分子量および7から18のHLB値を有する非イオン性直鎖ポリマー;
(iv)4から25%の脂肪酸;ならびに
(v)40から80%の水
を含む、最大12%の有機日焼け止め剤を含む日焼け止め剤組成物。 - 前記脂肪酸が前記組成物の8から20重量%で存在する、請求項1に記載の日焼け止め剤組成物。
- 有機日焼け止め剤の総量が最大で8%である、請求項1または2に記載の日焼け止め剤組成物。
- 前記修飾セルロースがメチルセルロースまたはヒドロキシエチルセルロースである、請求項1から3のいずれか一項に記載の日焼け止め剤組成物。
- 前記非イオン性ポリマーのHLBが15から18の範囲内である、請求項1から4のいずれか一項に記載の日焼け止め剤組成物。
- 前記非イオン性ポリマーが0.5から4%で存在する、請求項1から5のいずれか一項に記載の日焼け止め剤組成物。
- 前記UVA日焼け止め剤がジベンゾイルメタン誘導体、トリアジン誘導体、トリアゾン誘導体またはベンゾフェノン誘導体である、請求項1から6のいずれか一項に記載の日焼け止め剤組成物。
- 前記ジベンゾイルメタン誘導体が4−tert−ブチル−4’−メトキシジベンゾイルメタンである、請求項7に記載の日焼け止め剤組成物。
- 前記UV−B日焼け止め剤がベンゾフェノン類、アントラニレート類、サリチレート類、シンナメート類、カンファー類、ベンジリデンマロネート;トリアゾンまたはその誘導体のクラスより選択される、請求項1から8のいずれか一項に記載の日焼け止め剤組成物。
- 25℃における前記非イオン性ポリマーの1%水溶液の表面張力が40ダイン/cmより高い、請求項1から9のいずれか一項に記載の日焼け止め剤組成物。
- 前記脂肪酸が前記組成物の12重量%を超えて存在する、請求項1から10のいずれか一項に記載の日焼け止め剤組成物。
- 0.1から10%の石鹸をさらに含む、請求項1から11のいずれか一項に記載の日焼け止め剤組成物。
- 少なくとも15のSPF値を提供するための、請求項1から12のいずれか一項に記載の日焼け止め剤組成物の使用。
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EP12199401 | 2012-12-27 | ||
EP12199401.6 | 2012-12-27 | ||
PCT/EP2013/075836 WO2014102050A2 (en) | 2012-12-27 | 2013-12-06 | A sunscreen composition |
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JP2016503811A true JP2016503811A (ja) | 2016-02-08 |
JP6445981B2 JP6445981B2 (ja) | 2018-12-26 |
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US (1) | US20150328130A1 (ja) |
EP (1) | EP2938320B1 (ja) |
JP (1) | JP6445981B2 (ja) |
CN (1) | CN105120831B (ja) |
AR (1) | AR094293A1 (ja) |
BR (1) | BR112015015629A2 (ja) |
CA (1) | CA2896327C (ja) |
EA (1) | EA030286B9 (ja) |
MX (1) | MX360635B (ja) |
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CN113026136B (zh) * | 2021-03-20 | 2021-10-26 | 浙江佳轩汽车用品有限公司 | 用于汽车防晒保护套的聚乙烯纤维及其制备方法 |
WO2023247794A1 (en) | 2022-06-24 | 2023-12-28 | Nouryon Chemicals International B.V. | Polyvinyl alcohol film-forming polymers for alcohol-based sunscreen formulations and methods of using same |
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JP6445981B2 (ja) | 2018-12-26 |
US20150328130A1 (en) | 2015-11-19 |
CA2896327A1 (en) | 2014-07-03 |
CN105120831B (zh) | 2020-04-24 |
EA030286B9 (ru) | 2018-10-31 |
EA030286B1 (ru) | 2018-07-31 |
WO2014102050A2 (en) | 2014-07-03 |
WO2014102050A3 (en) | 2014-10-09 |
MX2015008432A (es) | 2016-07-07 |
EP2938320B1 (en) | 2018-09-12 |
ZA201504595B (en) | 2016-11-30 |
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EP2938320A2 (en) | 2015-11-04 |
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