JP2016500681A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016500681A5 JP2016500681A5 JP2015536990A JP2015536990A JP2016500681A5 JP 2016500681 A5 JP2016500681 A5 JP 2016500681A5 JP 2015536990 A JP2015536990 A JP 2015536990A JP 2015536990 A JP2015536990 A JP 2015536990A JP 2016500681 A5 JP2016500681 A5 JP 2016500681A5
- Authority
- JP
- Japan
- Prior art keywords
- responsive
- polycation
- hydrogel
- methacrylate
- acrylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261713610P | 2012-10-14 | 2012-10-14 | |
| US61/713,610 | 2012-10-14 | ||
| PCT/US2013/064887 WO2014059430A1 (en) | 2012-10-14 | 2013-10-14 | Delivery of small interfering rna and micro rna through membrane-disruptive, responsive nanoscalle hydrogels |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016500681A JP2016500681A (ja) | 2016-01-14 |
| JP2016500681A5 true JP2016500681A5 (enExample) | 2016-12-22 |
Family
ID=49510546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015536990A Ceased JP2016500681A (ja) | 2012-10-14 | 2013-10-14 | 膜破壊性の応答性ナノスケールヒドロゲルによる低分子干渉rna及びマイクロrnaの送達 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20150216814A1 (enExample) |
| EP (1) | EP2906242A1 (enExample) |
| JP (1) | JP2016500681A (enExample) |
| CA (1) | CA2888135A1 (enExample) |
| IL (1) | IL238245A0 (enExample) |
| WO (1) | WO2014059430A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016073706A1 (en) * | 2014-11-06 | 2016-05-12 | Board Of Regents, The University Of Texas System | Delivery of small interfering rna and micro rna through nanogels containing hydrophobic pseudo-peptides |
| CA3002786C (en) * | 2015-10-30 | 2021-09-07 | Bonac Corporation | Composition stably containing single-stranded nucleic acid molecule that suppresses expression of tgf-.beta.1 gene |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4060678A (en) * | 1975-02-11 | 1977-11-29 | Plastomedical Sciences, Inc. | Cationic hydrogels based on hydroxyalkyl acrylates and methacrylates |
| JP3713841B2 (ja) * | 1996-10-08 | 2005-11-09 | 荒川化学工業株式会社 | カチオン性微粒子ゲルおよびその製造方法 |
| US7378479B2 (en) * | 2002-09-13 | 2008-05-27 | Lubrizol Advanced Materials, Inc. | Multi-purpose polymers, methods and compositions |
| EP2285358A1 (en) * | 2008-06-03 | 2011-02-23 | Novartis AG | Pulsatile release of valsartan |
| GB201010831D0 (en) * | 2010-06-28 | 2010-08-11 | Ct Angewandte Nanotech Can | A micellular combination comprising a nanoparticle and a plurality of surfmer ligands |
-
2013
- 2013-10-14 EP EP13783770.4A patent/EP2906242A1/en not_active Withdrawn
- 2013-10-14 JP JP2015536990A patent/JP2016500681A/ja not_active Ceased
- 2013-10-14 CA CA2888135A patent/CA2888135A1/en not_active Abandoned
- 2013-10-14 WO PCT/US2013/064887 patent/WO2014059430A1/en not_active Ceased
-
2015
- 2015-04-12 IL IL238245A patent/IL238245A0/en unknown
- 2015-04-14 US US14/685,949 patent/US20150216814A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Li et al. | New route to amphiphilic core− shell polymer nanospheres: graft copolymerization of methyl methacrylate from water-soluble polymer chains containing amino groups | |
| Cao et al. | Recent advances of zwitterionic carboxybetaine materials and their derivatives | |
| Pandey et al. | Polyethylenimine: A versatile, multifunctional non-viral vector for nucleic acid delivery | |
| Nelson et al. | Balancing cationic and hydrophobic content of PEGylated siRNA polyplexes enhances endosome escape, stability, blood circulation time, and bioactivity in vivo | |
| Zintchenko et al. | Temperature dependent gene expression induced by PNIPAM-based copolymers: potential of hyperthermia in gene transfer | |
| Zurick et al. | Recent biomedical advances with polyampholyte polymers | |
| ES2655622T3 (es) | Una formulación de fármaco de liberación retardada | |
| CN105250214B (zh) | 一种氨基酸修饰的聚合物纳米水凝胶药物载体的制备方法 | |
| Ahmed et al. | Impact of the nature, size and chain topologies of carbohydrate–phosphorylcholine polymeric gene delivery systems | |
| Wu et al. | Recent progress in copolymer-mediated siRNA delivery | |
| Benoit et al. | Controlling mesenchymal stem cell gene expression using polymer-mediated delivery of siRNA | |
| JP2015505473A5 (ja) | 細胞培養のための合成接着培地 | |
| RU2017129933A (ru) | Доставка частиц гидрофобного активного средства | |
| Ahmed et al. | Cell line dependent uptake and transfection efficiencies of PEI–anionic glycopolymer systems | |
| JP2017513596A5 (enExample) | ||
| RU2013135454A (ru) | Системы доставки лекарств | |
| WO2012031113A3 (en) | Polymers and compositions | |
| JP2014505151A5 (enExample) | ||
| JP2005531649A (ja) | pH−感受性ポリマー | |
| Farid et al. | Silencing of the scavenger receptor (Class B–Type 1) gene using siRNA-loaded chitosan nanaoparticles in a HepG2 cell model | |
| JP2017535581A5 (enExample) | ||
| JP2015120756A5 (enExample) | ||
| Plamper et al. | Star-shaped poly [2-(dimethylamino) ethyl methacrylate] and its derivatives: toward new properties and applications | |
| JP2017514005A5 (enExample) | ||
| CN102973488A (zh) | 具有氧化还原/pH双重刺激响应性的纳米水凝胶及其制备方法和应用 |