JP2016185995A5 - - Google Patents

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Publication number
JP2016185995A5
JP2016185995A5 JP2016153074A JP2016153074A JP2016185995A5 JP 2016185995 A5 JP2016185995 A5 JP 2016185995A5 JP 2016153074 A JP2016153074 A JP 2016153074A JP 2016153074 A JP2016153074 A JP 2016153074A JP 2016185995 A5 JP2016185995 A5 JP 2016185995A5
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JP
Japan
Prior art keywords
day
disease
compound
use according
week
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JP2016153074A
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English (en)
Japanese (ja)
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JP6362644B2 (ja
JP2016185995A (ja
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Publication of JP2016185995A publication Critical patent/JP2016185995A/ja
Publication of JP2016185995A5 publication Critical patent/JP2016185995A5/ja
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Publication of JP6362644B2 publication Critical patent/JP6362644B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016153074A 2009-03-19 2016-08-03 高い経口バイオアベイラビリティを有するモルフィナン誘導体 Expired - Fee Related JP6362644B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16170209P 2009-03-19 2009-03-19
US61/161,702 2009-03-19

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2014046328A Division JP2014101388A (ja) 2009-03-19 2014-03-10 高い経口バイオアベイラビリティを有するモルフィナン誘導体

Publications (3)

Publication Number Publication Date
JP2016185995A JP2016185995A (ja) 2016-10-27
JP2016185995A5 true JP2016185995A5 (OSRAM) 2016-12-28
JP6362644B2 JP6362644B2 (ja) 2018-07-25

Family

ID=42738186

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2012500776A Expired - Fee Related JP5555890B2 (ja) 2009-03-19 2009-12-04 高い経口バイオアベイラビリティを有するモルフィナン誘導体
JP2014046328A Pending JP2014101388A (ja) 2009-03-19 2014-03-10 高い経口バイオアベイラビリティを有するモルフィナン誘導体
JP2014097613A Withdrawn JP2014139257A (ja) 2009-03-19 2014-05-09 高い経口バイオアベイラビリティを有するモルフィナン誘導体
JP2016153074A Expired - Fee Related JP6362644B2 (ja) 2009-03-19 2016-08-03 高い経口バイオアベイラビリティを有するモルフィナン誘導体

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2012500776A Expired - Fee Related JP5555890B2 (ja) 2009-03-19 2009-12-04 高い経口バイオアベイラビリティを有するモルフィナン誘導体
JP2014046328A Pending JP2014101388A (ja) 2009-03-19 2014-03-10 高い経口バイオアベイラビリティを有するモルフィナン誘導体
JP2014097613A Withdrawn JP2014139257A (ja) 2009-03-19 2014-05-09 高い経口バイオアベイラビリティを有するモルフィナン誘導体

Country Status (6)

Country Link
US (4) US20100240691A1 (OSRAM)
EP (2) EP2408303A4 (OSRAM)
JP (4) JP5555890B2 (OSRAM)
AU (1) AU2009342654B2 (OSRAM)
CA (1) CA2754984C (OSRAM)
WO (1) WO2010107457A1 (OSRAM)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5555890B2 (ja) * 2009-03-19 2014-07-23 アルカーメス ファーマ アイルランド リミテッド 高い経口バイオアベイラビリティを有するモルフィナン誘導体
AU2010326676B2 (en) * 2009-12-04 2013-03-14 Alkermes Pharma Ireland Limited Morphinan derivatives for the treatment of drug overdose
HRP20190169T1 (hr) 2010-08-23 2019-03-22 Alkermes Pharma Ireland Limited Postupci liječenja povećanja tjelesne težine inducirane antipsihoticima
JP2015504865A (ja) * 2011-12-15 2015-02-16 アルカーメス ファーマ アイルランド リミテッド オピオイドアゴニストと組み合わせたサミドルファン（ａｌｋｓ３３）
US8822488B2 (en) * 2011-12-15 2014-09-02 Alkermes Pharma Ireland Limited Compositions of buprenorphine and μ antagonists
US10195191B2 (en) 2011-12-15 2019-02-05 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
US8637538B1 (en) 2012-12-14 2014-01-28 Trevi Therapeutics, Inc. Methods for treatment of pruritis
US8987289B2 (en) 2012-12-14 2015-03-24 Trevi Therapeutics, Inc. Methods for treating pruritus
US20140179727A1 (en) 2012-12-14 2014-06-26 Trevi Therapeutics, Inc. Methods for treating pruritus
NZ631018A (en) 2013-05-24 2017-12-22 Alkermes Pharma Ireland Ltd Morphan and morphinan analogues, and methods of use
WO2014190271A2 (en) 2013-05-24 2014-11-27 Alkermes Pharma Ireland Limted Methods for treating depressive symptoms
AU2019309913B2 (en) 2018-07-23 2025-02-27 Trevi Therapeutics, Inc. Treatment of chronic cough, breathlessness and dyspnea
EP4087569A4 (en) 2020-01-10 2024-01-24 Trevi Therapeutics, Inc. METHODS OF ADMINISTRATION OF NALBUPHINE
US20230111856A1 (en) * 2020-03-02 2023-04-13 University Of Southern California Opioid receptor antagonists
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet
WO2025038406A1 (en) * 2023-08-11 2025-02-20 Virginia Commonwealth University Design, synthesis, and biological evaluation of nitrogen-walk derivatives of nan as mu opioid receptor selective modulators

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856795A (en) * 1972-04-25 1974-12-24 American Home Prod Process for preparation of secondary amines from tertiary amines
US4032529A (en) * 1974-09-20 1977-06-28 Sterling Drug Inc. Aminomethanobenzazocine intermediates
US3957793A (en) * 1974-09-20 1976-05-18 Sterling Drug Inc. Hydroxyiminobenzazocines
US4127577A (en) * 1975-11-24 1978-11-28 Sterling Drug Inc. Aminomethanobenzazocine process
US4205171A (en) * 1976-01-12 1980-05-27 Sterling Drug Inc. Aminomethanobenzazocines and nitromethanobenzazocines
US4464378A (en) * 1981-04-28 1984-08-07 University Of Kentucky Research Foundation Method of administering narcotic antagonists and analgesics and novel dosage forms containing same
US4649200A (en) * 1986-05-08 1987-03-10 Regents Of The University Of Minnesota Substituted pyrroles with opioid receptor activity
US5028612A (en) * 1990-03-22 1991-07-02 Hillel Glover Method for treating emotional numbness
US5258386A (en) * 1991-06-05 1993-11-02 The United States Of America As Represented By The Secretary Of The Army (+)-3-substituted-N alkylmorphinans, synthesis and use as anticonvulsant and neuroprotective agents
US5607941A (en) * 1992-06-26 1997-03-04 Boehringer Ingelheim Kg Useful for treating neurodegenerative diseases
US5512593A (en) * 1993-03-02 1996-04-30 John S. Nagle Composition and method of treating depression using natoxone or naltrexone in combination with a serotonin reuptake inhibitor
AR005423A1 (es) * 1996-01-10 1999-06-23 Smithkline Beecham Spa Derivados morfinoides condensados con heterociclos (ii), su uso como sustancia terapeutica y para preparar medicamentos, composiciones farmaceuticasque los contienen y procedimiento para preparar dichos derivados.
GB9912411D0 (en) * 1999-05-28 1999-07-28 Pfizer Ltd Compounds useful in therapy
AU2002227135B2 (en) * 2000-10-31 2008-01-03 Rensselaer Polytechnic Institute 8- substituted-2, 6-methano-3-benzazocines and 3-substituted morphinanes as opioid receptor binding agents
AU2005245403B2 (en) * 2004-05-14 2012-04-19 Janssen Pharmaceutica N.V. Carboxamido opioid compounds
US20060063792A1 (en) * 2004-09-17 2006-03-23 Adolor Corporation Substituted morphinans and methods of their use
EP2251330B1 (en) * 2004-11-05 2012-05-09 Rensselaer Polytechnic Institute 4-Hydroxybenzomorphans
US20070099947A1 (en) * 2005-11-03 2007-05-03 Alkermes, Inc. Methods and compositions for the treatment of brain reward system disorders by combination therapy
WO2007089934A2 (en) * 2006-02-01 2007-08-09 Alkermes, Inc. Methods of treating alcoholism and alcohol related disorders using combination drug therapy and swellable polymers
EA020658B1 (ru) * 2007-08-09 2014-12-30 Ренссилэйер Политекник Инститьют Четвертичные опиоидные карбоксамиды
JP5555890B2 (ja) * 2009-03-19 2014-07-23 アルカーメス ファーマ アイルランド リミテッド 高い経口バイオアベイラビリティを有するモルフィナン誘導体
US20120149724A1 (en) * 2009-06-04 2012-06-14 The General Hospital Corporation Modulating endogenous beta-endorphin levels
US9211293B2 (en) * 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
JP5929635B2 (ja) * 2012-08-30 2016-06-08 株式会社デンソー 多段式横型鍛造装置

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