JP2016169388A5 - - Google Patents
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- Publication number
- JP2016169388A5 JP2016169388A5 JP2016086958A JP2016086958A JP2016169388A5 JP 2016169388 A5 JP2016169388 A5 JP 2016169388A5 JP 2016086958 A JP2016086958 A JP 2016086958A JP 2016086958 A JP2016086958 A JP 2016086958A JP 2016169388 A5 JP2016169388 A5 JP 2016169388A5
- Authority
- JP
- Japan
- Prior art keywords
- alkylene
- group
- amine
- amine polymer
- polymer according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000002947 alkylene group Chemical group 0.000 claims 23
- 150000001412 amines Chemical class 0.000 claims 23
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims 18
- 229920000642 polymer Polymers 0.000 claims 16
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 10
- 125000000753 cycloalkyl group Chemical group 0.000 claims 10
- 239000000178 monomer Substances 0.000 claims 7
- 150000001408 amides Chemical class 0.000 claims 5
- 125000003118 aryl group Chemical group 0.000 claims 5
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 5
- 150000002148 esters Chemical class 0.000 claims 5
- 125000000524 functional group Chemical group 0.000 claims 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- RZTDESRVPFKCBH-UHFFFAOYSA-N 1-methyl-4-(4-methylphenyl)benzene Chemical group C1=CC(C)=CC=C1C1=CC=C(C)C=C1 RZTDESRVPFKCBH-UHFFFAOYSA-N 0.000 claims 3
- 125000000732 arylene group Chemical group 0.000 claims 3
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000004104 aryloxy group Chemical group 0.000 claims 2
- 125000001475 halogen functional group Chemical group 0.000 claims 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 238000006116 polymerization reaction Methods 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 238000008214 LDL Cholesterol Methods 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30781610P | 2010-02-24 | 2010-02-24 | |
| US30781910P | 2010-02-24 | 2010-02-24 | |
| US61/307,816 | 2010-02-24 | ||
| US61/307,819 | 2010-02-24 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012555154A Division JP5964247B2 (ja) | 2010-02-24 | 2011-02-24 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017040404A Division JP2017101258A (ja) | 2010-02-24 | 2017-03-03 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016169388A JP2016169388A (ja) | 2016-09-23 |
| JP2016169388A5 true JP2016169388A5 (show.php) | 2016-11-04 |
| JP6431499B2 JP6431499B2 (ja) | 2018-11-28 |
Family
ID=43975199
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012555154A Expired - Fee Related JP5964247B2 (ja) | 2010-02-24 | 2011-02-24 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
| JP2016086958A Expired - Fee Related JP6431499B2 (ja) | 2010-02-24 | 2016-04-25 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
| JP2017040404A Withdrawn JP2017101258A (ja) | 2010-02-24 | 2017-03-03 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012555154A Expired - Fee Related JP5964247B2 (ja) | 2010-02-24 | 2011-02-24 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017040404A Withdrawn JP2017101258A (ja) | 2010-02-24 | 2017-03-03 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20130189215A1 (show.php) |
| EP (2) | EP2538947B1 (show.php) |
| JP (3) | JP5964247B2 (show.php) |
| CN (2) | CN102858347B (show.php) |
| AU (2) | AU2011220745B2 (show.php) |
| BR (1) | BR112012021448A2 (show.php) |
| CA (1) | CA2790899C (show.php) |
| ES (1) | ES2598500T3 (show.php) |
| GB (1) | GB2490853B (show.php) |
| WO (1) | WO2011106545A1 (show.php) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102858817B (zh) | 2010-02-24 | 2015-09-02 | 瑞立普萨公司 | 用作胆汁酸螯合剂的交联聚乙烯胺、聚烯丙胺和乙烯亚胺 |
| RU2612795C2 (ru) | 2010-02-24 | 2017-03-13 | Релипса, Инк. | Аминосодержащие полимеры для применения в качестве секвестрантов желчных кислот |
| US20130244234A1 (en) * | 2012-01-23 | 2013-09-19 | Glc Biotechnology, Inc. | Stool collection methods for analysis of dna in stool |
| JP6227535B2 (ja) * | 2012-08-30 | 2017-11-08 | 株式会社三和化学研究所 | 脂質異常症の予防又は治療薬 |
| SI3578185T1 (sl) | 2013-06-05 | 2021-01-29 | Tricida Inc. | Polimeri, ki vežejo protone za oralno administracijo |
| ES2895625T3 (es) | 2014-04-16 | 2022-02-22 | Uab Res Found | Nanoporos de MSP y usos de los mismos |
| JP2017517550A (ja) | 2014-06-13 | 2017-06-29 | ユナイテッド セラピューティクス コーポレイション | トレプロスチニル製剤 |
| CA2969238C (en) * | 2014-12-10 | 2023-10-17 | Tricida, Inc. | Proton-binding polymers for oral administration |
| MA41202A (fr) | 2014-12-18 | 2017-10-24 | Genzyme Corp | Copolymères polydiallymine réticulé pour le traitement du diabète de type 2 |
| US11090354B2 (en) * | 2015-08-06 | 2021-08-17 | The Johns Hopkins University | Composition and method for treatment of metabolic disorders |
| CN106967217A (zh) * | 2016-01-14 | 2017-07-21 | 华南理工大学 | 聚咪唑类化合物及其原位制备方法和应用 |
| WO2017193024A1 (en) | 2016-05-06 | 2017-11-09 | Tricida, Inc. | Hcl-binding compositions for and method of treating acid-base disorders |
| AU2017388956A1 (en) | 2016-12-28 | 2019-07-11 | Fujifilm Corporation | Emulsion of nitrogen atom-containing polymer or salt thereof, production method therefor, and production method for particles |
| EP3698799B1 (en) | 2017-10-16 | 2022-01-26 | FUJIFILM Corporation | Hyperphosphatemia treatment agent |
| IL319146A (en) | 2017-11-03 | 2025-04-01 | Tricida Inc | Compositions for and method of treating acid-base disorders |
| CN109932349B (zh) * | 2019-04-04 | 2021-04-20 | 济南大学 | 一种检测次氯酸的有机硅小分子荧光探针 |
| CN114340632B (zh) * | 2019-08-30 | 2024-09-17 | 赛特瑞恩股份有限公司 | 用于治疗或预防非酒精性脂肪性肝炎（nash）的药物组合物 |
| MX2022003384A (es) | 2019-09-20 | 2022-06-27 | Glyscend Inc | Polimeros que contienen acido fenil boronico sustituido y metodos de uso. |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60209523A (ja) * | 1984-04-03 | 1985-10-22 | Mitsubishi Petrochem Co Ltd | コレステロ−ル低下剤 |
| US4600578A (en) * | 1984-05-11 | 1986-07-15 | Bristol-Myers Company | Method of inhibiting diarrhea |
| US4649048A (en) * | 1984-05-11 | 1987-03-10 | Bristol-Myers Company | Novel bile sequestrant resin |
| DE59300925D1 (de) * | 1992-03-28 | 1995-12-21 | Hoechst Ag | Arzneimittel aus Polyhydroxymethylenderivaten, Verfahren zu deren Herstellung und Verwendung. |
| JPH066667A (ja) | 1992-06-22 | 1994-01-14 | Canon Inc | ぶれ検出装置及びぶれ補正装置 |
| US5631365A (en) | 1993-09-21 | 1997-05-20 | Schering Corporation | Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents |
| US5414068A (en) | 1994-01-24 | 1995-05-09 | Rohm And Haas Company | Crosslinked anion exchange particles and method for producing the particles |
| CN1189168A (zh) * | 1995-06-06 | 1998-07-29 | 吉尔特药品公司 | 用于清除胆固醇的含疏水杂原子的螯合剂 |
| JP4156684B2 (ja) * | 1996-03-05 | 2008-09-24 | 三菱化学株式会社 | 高リン血症予防および／または治療剤 |
| EP1015542A1 (en) * | 1997-09-15 | 2000-07-05 | The Procter & Gamble Company | Laundry detergent compositions with anionically modified, cyclic amine based polymers |
| US6147183A (en) * | 1997-09-15 | 2000-11-14 | Basf Aktiengesellschaft | Amphoteric amine based polymers having a net cationic charge and process for their production |
| US5900233A (en) * | 1997-10-16 | 1999-05-04 | Day; Charles E. | Epichlorohydrin and 1-(3-aminopropyl) imidazole copolymer and its use in treating irritable bowel syndrome |
| CN1163576C (zh) * | 1998-10-13 | 2004-08-25 | 宝洁公司 | 含环胺基聚合物与疏水改性羧甲基纤维素混合物的洗衣洗涤剂组合物 |
| US6472364B1 (en) * | 1998-10-13 | 2002-10-29 | The Procter & Gamble Company | Detergent compositions or components |
| AU1906500A (en) * | 1999-10-29 | 2001-05-14 | Procter & Gamble Company, The | Laundry detergent compositions with fabric care |
| JP2002068985A (ja) * | 2000-08-30 | 2002-03-08 | Mitsubishi-Tokyo Pharmaceuticals Inc | 薬剤性肝障害治療薬 |
| CA2430122C (en) * | 2000-11-28 | 2010-08-24 | Mitsubishi Pharma Corporation | Antiobesity agent and health food |
| US7879869B2 (en) * | 2001-07-30 | 2011-02-01 | Mitsubishi Tanabe Pharma Corporation | Drugs for ameliorating postcibal hyperglycemia |
| JP2003113091A (ja) * | 2001-10-02 | 2003-04-18 | Sekisui Chem Co Ltd | 胆汁酸特異的認識ポリマー及びコレステロール低下剤 |
| US7608674B2 (en) * | 2003-11-03 | 2009-10-27 | Ilypsa, Inc. | Pharmaceutical compositions comprising cross-linked small molecule amine polymers |
| US7459502B2 (en) * | 2003-11-03 | 2008-12-02 | Ilypsa, Inc. | Pharmaceutical compositions comprising crosslinked polyamine polymers |
| WO2005097806A1 (en) * | 2004-03-26 | 2005-10-20 | Eli Lilly And Company | Compounds and methods for treating dyslipidemia |
| JP4896480B2 (ja) * | 2004-10-01 | 2012-03-14 | 第一三共ヘルスケア株式会社 | 陰イオン交換樹脂の粒子状組成物 |
| JP6218355B2 (ja) * | 2011-02-10 | 2017-10-25 | ソニー株式会社 | 濾材 |
| CN105900233A (zh) * | 2013-12-13 | 2016-08-24 | Wow研究中心有限公司 | 半导体装置及其制造方法 |
| CN106147183A (zh) * | 2015-04-01 | 2016-11-23 | 合肥杰事杰新材料股份有限公司 | 一种pc/abs合金材料及其制备方法 |
-
2011
- 2011-02-24 CN CN201180020473.2A patent/CN102858347B/zh not_active Expired - Fee Related
- 2011-02-24 BR BR112012021448A patent/BR112012021448A2/pt not_active Application Discontinuation
- 2011-02-24 EP EP11707039.1A patent/EP2538947B1/en not_active Not-in-force
- 2011-02-24 CN CN201610881008.2A patent/CN106478948B/zh not_active Expired - Fee Related
- 2011-02-24 WO PCT/US2011/026102 patent/WO2011106545A1/en not_active Ceased
- 2011-02-24 EP EP16184141.6A patent/EP3130343B1/en not_active Not-in-force
- 2011-02-24 ES ES11707039.1T patent/ES2598500T3/es active Active
- 2011-02-24 GB GB1216799.5A patent/GB2490853B/en not_active Expired - Fee Related
- 2011-02-24 AU AU2011220745A patent/AU2011220745B2/en not_active Ceased
- 2011-02-24 CA CA2790899A patent/CA2790899C/en not_active Expired - Fee Related
- 2011-02-24 JP JP2012555154A patent/JP5964247B2/ja not_active Expired - Fee Related
- 2011-02-24 US US13/581,102 patent/US20130189215A1/en not_active Abandoned
-
2016
- 2016-04-25 JP JP2016086958A patent/JP6431499B2/ja not_active Expired - Fee Related
-
2017
- 2017-02-24 AU AU2017201276A patent/AU2017201276B2/en not_active Ceased
- 2017-03-03 JP JP2017040404A patent/JP2017101258A/ja not_active Withdrawn
-
2019
- 2019-02-08 US US16/271,296 patent/US20190169342A1/en not_active Abandoned