JP2016069322A - Retention agent for peppermint oil, and centipede pesticide using the same - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide: a novel retention agent that can, when pesticidally controlling a centipede using a peppermint oil as a pesticidal ingredient, be used regardless of indoor or outdoor, and that can realize a pesticidal ingredient for a long period of time; and the retention agent-containing pesticide.SOLUTION: The solution means is: a retention agent for peppermint oil having a menthone glycerin acetal as an active ingredient; and a centipede pesticide having a peppermint oil as a pesticidal ingredient and containing the retention agent and in which the weight ratio of the peppermint oil and the menthone glycerin acetal is in a predetermined range of weight ratio.SELECTED DRAWING: None

Description

  TECHNICAL FIELD The present invention relates to a novel mint oil retentive agent, and the mint centipede insecticide containing the mint oil and the mint oil retentive agent.

  Some of the terpene compounds and / or essential oils are used as fragrances, cooling agents, insecticides and the like. Among such insecticides, there are those which have been added a retentive agent in order to suppress the transpiration of easily transpirationable components and to maintain the medicinal effect for a longer period.

  For example, it is a gel-form preparation having an egg-killing ingredient formed by gelling an O / W emulsion, containing a terpene compound and / or essential oil as an active ingredient as an egg-killing ingredient for clothing pests, Gel-like insect repellents that disclose polyhydric alcohols such as ethylene glycol, diethylene glycol, polyethylene glycol, propylene glycol, and glycerin, animal and vegetable oils and fats, and the like are known (for example, see Patent Document 1).

  On the other hand, an insecticide comprising a pyrethroid compound, mint oil or orange oil is 0.001 to 1% by weight of the total amount of the insecticide composition, and 2,3-dihydrodecafluoropentane is 5 to 30% of the total amount of the insecticide composition. Insecticide compositions characterized by containing wt% are known (for example, see Patent Document 2).

  Moreover, the present applicant has found the repellent performance of menthone glycerin acetal against food pests as an earlier application, and has developed a repellent containing a predetermined amount of the menthogrineline acetal (see, for example, Patent Document 3). ).

  Menthogrineline acetal is a synthetic compound that is not originally contained in essential oils such as peppermint oil. In addition to the use according to Patent Document 3, the menthoglycerin acetal is conventionally used as a cooling agent.

JP 2004-099568 A Japanese Patent No. 4316182 Japanese Patent No. 5204399

The invention according to Patent Document 1 specifically uses limonene and / or pinene as an active ingredient to kill eggs of pests (for example, moths in the examples).
Further, in the same document, the gel insect repellent of the present invention includes an insecticidal component, a repellent component, an aromatic component, a deodorizing component, a synergist, an antioxidant, an antiseptic, as long as the effects of the invention are exhibited. It is disclosed that a retention agent, a wetting agent, a volatilization adjusting agent, and the like may be appropriately blended, and a retention agent such as cellulose derivatives such as methyl cellulose, ethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, a wetting agent, and volatilization adjustment. Agents are illustrated.

  It is disclosed that limonene, pinene, anethole and the essential oils containing these among the egg-killing ingredients can be accompanied by an insecticidal ingredient depending on the blending amount. However, although the invention according to the above-mentioned Patent Document 1 is effective for the ovulation of clothing pests and larvae / adults, it is a gel-form preparation having an ovicidal component formed by gelling an O / W emulsion. As a gel-like insect repellent containing mint oil as an active ingredient and a retention agent, for example, polyhydric alcohols such as ethylene glycol, diethylene glycol, polyethylene glycol, propylene glycol and glycerin, animal and vegetable oils and fats, the retention effect It is unknown whether it can kill even other completely different species of pests.

  That is, as described in paragraph 0002 of the above-mentioned Patent Document 2, it cannot be said that a drug as a means for increasing the insecticidal power is always increased for any insecticide, and the effect is exhibited by the target pest. In some cases, it may not be demonstrated. Therefore, in order to increase the insecticidal power against specific target pests, the possibility of various means is being studied.

  In addition, according to Patent Document 2, as described above, 2,3-dihydrodecafluoropentane is used as an insecticidal potentiator, and it is described that an effect on American cockroaches, ants, and spiders can be obtained. . For this reason, mint oil is included as an option for the insecticide according to the above cited reference 2. For example, it is unclear whether the same effect can be obtained for pests other than the target pest.

  Furthermore, 2,3-dihydrodecafluoropentane, which is the insecticide enhancing agent most characteristic of the invention according to the cited document 2, is a fluorine compound, and the nature of the insecticide enhancing agent is more friendly to the natural environment. It is required to be. In particular, the larger the arthropod, the more inevitably the amount of insecticides and insecticide-enhancing agents used will be. Therefore, when used indoors, it is safer and more friendly to the natural environment. Is required.

By the way, the centipede belonging to the class of large arthropods is active not only outdoors but also indoors and has high toxicity. For this reason, the necessity for extermination is very high.
Centipedes are very vital and have an exoskeleton that includes the chest and abdomen compared to large moss, etc., and are resistant to penetration of the insecticides even when sprayed with insecticides. Is considered high. For example, cybere 0.5SC (trade name, pyrethroid insecticide and main insecticidal component β-cyfluthrin), which is an insecticidal component, is sprayed on arachnids at a prescribed concentration. In the case of a centipede, it has been confirmed that it takes about 15 minutes to die.
For this reason, there is a demand for highly safe insecticides and retention agents that are friendly to the natural environment so that the centipede can be safely removed even indoors.

  The present invention has been made in view of the above circumstances, and the invention intends to provide a mint oil-retaining agent that is more environmentally friendly than that of mint oil as an insecticide. Let it be an issue.

  Another object of the present invention is to provide an insecticide that uses centipede as a target pest, mint oil as an insecticidal component, and contains a retention agent for mint oil.

This invention makes the retention agent for mint oil which uses the menstrual glycerin acetal shown below as an active ingredient as a means for solving the invention.

  Further, the present invention comprises mint oil as an insecticidal component, containing a retention agent for mint oil containing mentholglycerin acetal as an active ingredient, and the mint oil is 5 to 10% by weight based on the total amount of the drug, and An insecticide characterized in that the weight ratio of mint oil and MGA is 100: 3 to 15% is a means for solving the problems.

  According to the invention according to claim 1, by adding menthol glycerin acetal that functions as a novel retention agent to mint oil that is an insecticidal component, other terpenes and essential oils are added without adding menthol glycerin acetal. Compared to the case, it is possible to obtain a holding effect dramatically.

  According to the invention according to claim 2, mint oil is used as an insecticidal component, the retentive agent according to claim 1 is contained, and the mint oil is 5 to 10% by weight based on the total amount of the drug, and Insecticide for centipede with mint oil / menthol glycerin acetal weight ratio (mint oil: menthol glycerin acetal) of 100: 3 to 100: 15. In this state, due to the remarkable retention effect of mentha glycerin acetal on mint oil, sustained release of mint oil, which is an insecticidal component, against centipede can be continued over a long period of time, and an insecticidal effect can be exhibited.

  The centipede insecticides according to the examples of the present invention are shown below. In addition, this invention is not limited to what is shown in a following example.

  The chemical | medical agent which comprises the insecticide for centipedes which concerns on the Example of this invention is comprised as an aqueous solution which added 0.3 weight% of menthic glycerine acetal with respect to 5 weight% of mint oil.

  Clarification of the retention effect obtained by adding mentholglycerin acetal to mint oil, which is an insecticidal component, and the retention effect obtained by adding menthoglyserin acetal to other insecticidal components Therefore, the following sustained release comparative test was conducted.

(Sustained release comparative test)
Below, mint oil, eucalyptus oil, d-limonene (orange oil), α-pinene (turpentine oil), citronellal, p-cymene, and a mixture of these samples with 5% by weight of menthoglyserin acetal, A filter paper having a diameter of 125 mm was impregnated with 0.5 ml, the filter paper was hung indoors, and the weight was measured at each elapsed time. The residual rate (%) was calculated from the weight of each specimen. Hereinafter, each numerical value in Tables 1 to 6 indicates the remaining rate (%).

In the state in which menth glycerin acetal was added to mint oil, an improvement in the residual rate of 8% was observed after 3 hours and after 4 hours, compared with the case where mint oil alone was measured alone.

In the state in which menthone glycerin acetal was added to limonene, the remaining rate was improved by 1.7% after 3 hours and about 1.1% after 4 hours, compared with the case where only limonene was measured alone. .

In the state of adding menthol glycerin acetal to eucalyptus oil, compared with the case where only eucalyptus oil was measured alone, the improvement of the residual rate was hardly obtained in both 2 hours and 2.5 hours. .

In the state in which menthone glycerin acetal is added to citronellal, the residual rate from 0.5 hours to 1 hour is improved by 1.5%, and after 1.5 hours, it is about 3.2% to 2.1%. It was a result of improvement. Although it was better than limonene and eucalyptus oil, it was not possible to obtain a remarkable improvement.

In a state in which menthone glycerin acetal was added to p-cymene (p-cymene), the improvement in the residual rate was approximately 2%, compared with the case where only p-cymene was measured alone.

  In the state where menthone glycerin acetal was added to α-pinene, the improvement in the residual rate was less than 1% compared to the case where only α-pinene was measured alone.

  As described above, it has been found that the improvement in the residual rate when adding menthoglucerin acetal to mint oil is remarkably high. As a result, it was found that the residual rate of the insecticidal component can be greatly improved by using mint oil in particular as the insecticidal component and combining menthoglyserin acetal as the retention agent.

  Next, in order to confirm the insecticidal performance, the following insecticidal test was performed on the insecticide according to the present example, in which menthoglycerin acetal was added as a retention agent to mint oil, which is an insecticidal component.

(Insecticide test 1: filter paper contact method)
1. Test method 640 μL (equivalent to 100 mL / m ² ) was dropped on the surface of a qualitative filter paper (ADVANTEC No. 1) having a diameter of 90 mm and air-dried for 1 hour, and then the bottom of a polypropylene cup having a diameter of 94 mm, a height of 95 mm, and a capacity of 250 mL. The Tobism cadet was introduced one by one as a test insect. The time until lethality of the test insects was measured. Table 7 below shows the insecticidal effect for each sample. Here, “good” indicates that the test insect died within 24 hours after the introduction. “Yes” indicates that the test insect survived up to 24 hours after injection and died within 48 hours after injection. “No” indicates that the test insect survived more than 48 hours after the introduction.

  Samples were mint oil-only preparations (mint oil 3 wt%, 4 wt%, and 5 wt% formulations), and mint oil 5 wt% menth glycerin acetal (0.15 wt%, 0.3 wt% and 0.5 wt% of each preparation product), and an ethanol solution containing 10 wt% of menthone glycerin acetal.

2. Test results

An insecticidal effect on centipede appears with a mint oil 5% by weight formulation, but it took more than 24 hours to die of the centipede with the mint oil 5% by weight formulation. Also, the time until death varied greatly, and the insecticidal effect was unstable.
On the other hand, in the preparation obtained by adding menthoglycerin acetal to the mint oil 5% by weight preparation, the time to death of the centipede was shortened within 24 hours, and a stable insecticidal effect was obtained.
In addition, the 10 weight% ethanol solution of menthong glycerol acetal is for confirming the influence on the insecticidal performance of menth glycerol acetal itself.

From the above, the weight ratio of mint oil in the preparation is 5% by weight or more with respect to the total amount of the preparation, and menthol glycerin acetal is 0.15% by weight with respect to 5% by weight of mint oil. It has been found that if the amount of menthone glycerin acetal is 3% by weight or more relative to the weight%, an insecticidal effect against centipedes can be exhibited.
Further, the weight ratio of mint oil in the preparation is 5% by weight or more with respect to the total amount of the preparation, and menthol glycerin acetal is 0.3% by weight with respect to 5% by weight of mint oil, that is, mint oil 100% It was found that if the menthoglyserin acetal is 6% by weight or more with respect to%, a more stable insecticidal effect can be exerted against centipedes.
Further, the weight ratio of mint oil in the preparation is 5% by weight or more with respect to the total amount of the preparation, and menth glycerin acetal is 0.5% by weight with respect to mint oil, that is, mint oil is 100% by weight. It was confirmed that a stable insecticidal effect against centipedes could be exhibited even when the menthoglyserin acetal was 10% by weight with respect to%.
On the other hand, if the weight ratio of menthone glycerin acetal exceeds 15% by weight with respect to 100% by weight of mint oil, the preparation remains in a sticky state after use of the insecticide in a room or the like, which is not preferable. In addition, it is considered that the menth glycerin acetal remaining in this state is unnecessary as a component that provides a retention effect on mint oil.
If the weight ratio of menthone glycerin acetal to 100% by weight of mint oil is less than 3% by weight, the retention effect is insufficient, and the insecticidal effect against centipede becomes unstable, which is not preferable.

If the mint oil content in the centipede insecticide preparation exceeds 10% by weight, the odor caused by the mint becomes strong, making it unsuitable as a product.
For this reason, as an insecticide, the content of mint oil is 5% by weight to 10% by weight with respect to the total amount of the insecticide preparation, and the content ratio of menthoglycerin acetal to mint oil is preferably 3% by weight or more, preferably It is 6% by weight or more, and can be effective when the weight ratio to mint oil is up to 15% by weight.

(Insecticide test 2)
In addition, in order to confirm the efficacy of this preparation on smaller arthropods, an experiment was also conducted on insecticidal performance against stink bugs as an example.
1. Test Method A qualitative filter paper (ADVANTEC No. 1) having a diameter of 90 mm was laid on the inner bottom of a bottomed cylindrical container having a diameter of 100 mm and a depth of 100 mm, and 5 each of the test insects, the winged beetle, were introduced. After spraying about 0.8 g of the reagent agent toward the insects with an atomizer, a lid having a plurality of small holes was placed. Absorbent cotton moistened with water was placed on the lid to prevent drying. After being left for 15 hours, the life and death of the test insects were determined.
This test was performed twice.
2. Test results

  Mentoglycerin acetal 0.3 wt% ethanol solution showed death of one test insect in the first test, but no death was observed in the second test. On the other hand, in 99.5% by weight ethanol, one death was observed in both the first and second tests. Therefore, the insecticidal effect of the menthoglycerin acetal in a 0.3% by weight ethanol solution of menthoglycerin acetal. Is not considered acceptable.

Neither mentha glycerin acetal-containing mint oil (insecticidal component) 3 wt% ethanol solution nor mint oil 5 wt% ethanol solution did not yield 100% test insect mortality, but only 50% and 60%, respectively. ing.
On the other hand, the mortality rate of test insects was 100% for mint oil 3% by weight, menthous glycerin acetal 0.3% by weight ethanol solution, and mint oil 5% by weight, menth glycerin acetal 0.3% by weight ethanol solution. It was possible, and sufficient effectiveness was recognized.

  On the other hand, if the content of mint oil in the preparation for insecticides against stink bugs according to this example exceeds 10% by weight, the odor due to mint will become strong and not suitable as a product. For this reason, as an insecticide, the content of mint oil is 3% by weight to 10% by weight with respect to the total amount of the insecticide preparation, and the content ratio of menthoglyserine acetal to mint oil is 6% by weight or more and 10% by weight. It can be effective in the range up to%.

From the above, the present invention aims to exterminate centipedes, but as an application example, it has been confirmed that the present invention also has effectiveness against some other small arthropods, stink bugs.

Claims (2)

Mentha glycerin acetal active ingredient for mint oil. A mint oil is used as an insecticidal component, the retentive agent according to claim 1 is contained, the mint oil is 5 to 10% by weight based on the total amount of the drug, and a weight ratio of the mint oil and menth glycerin acetal is 100: An insecticide for centipede, which is 3 to 15.