JP2016029098A5 - - Google Patents
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- Publication number
- JP2016029098A5 JP2016029098A5 JP2015221770A JP2015221770A JP2016029098A5 JP 2016029098 A5 JP2016029098 A5 JP 2016029098A5 JP 2015221770 A JP2015221770 A JP 2015221770A JP 2015221770 A JP2015221770 A JP 2015221770A JP 2016029098 A5 JP2016029098 A5 JP 2016029098A5
- Authority
- JP
- Japan
- Prior art keywords
- butylcyclohexane
- perfluoro
- contrast agent
- shell
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- VLTXBOGHSBHSAC-UHFFFAOYSA-N 1,1,2,2,3,3,4,4,5,5,6-undecafluoro-6-[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]cyclohexane Chemical compound FC(F)(F)C(C(F)(F)F)(C(F)(F)F)C1(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C1(F)F VLTXBOGHSBHSAC-UHFFFAOYSA-N 0.000 claims 23
- 239000002872 contrast media Substances 0.000 claims 15
- 241001465754 Metazoa Species 0.000 claims 8
- 239000000839 emulsion Substances 0.000 claims 7
- 238000003384 imaging method Methods 0.000 claims 7
- 238000002405 diagnostic procedure Methods 0.000 claims 6
- 239000003995 emulsifying agent Substances 0.000 claims 5
- 239000003446 ligand Substances 0.000 claims 5
- 239000002105 nanoparticle Substances 0.000 claims 5
- 150000003904 phospholipids Chemical class 0.000 claims 5
- 238000000034 method Methods 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 230000002285 radioactive effect Effects 0.000 claims 3
- -1 radioactive labels Substances 0.000 claims 3
- 239000000439 tumor marker Substances 0.000 claims 3
- 238000002059 diagnostic imaging Methods 0.000 claims 2
- 230000005298 paramagnetic effect Effects 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 238000002595 magnetic resonance imaging Methods 0.000 claims 1
- WTWWXOGTJWMJHI-UHFFFAOYSA-N perflubron Chemical compound FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br WTWWXOGTJWMJHI-UHFFFAOYSA-N 0.000 claims 1
- 229960001217 perflubron Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09166955.6 | 2009-07-31 | ||
| EP09166955 | 2009-07-31 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012522296A Division JP5840609B2 (ja) | 2009-07-31 | 2010-07-21 | イメージングに用いるパーフルオロ化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016029098A JP2016029098A (ja) | 2016-03-03 |
| JP2016029098A5 true JP2016029098A5 (enExample) | 2016-08-18 |
Family
ID=43304070
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012522296A Expired - Fee Related JP5840609B2 (ja) | 2009-07-31 | 2010-07-21 | イメージングに用いるパーフルオロ化合物 |
| JP2015221770A Pending JP2016029098A (ja) | 2009-07-31 | 2015-11-12 | イメージングに用いるパーフルオロ化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012522296A Expired - Fee Related JP5840609B2 (ja) | 2009-07-31 | 2010-07-21 | イメージングに用いるパーフルオロ化合物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20120128589A1 (enExample) |
| EP (1) | EP2459235B1 (enExample) |
| JP (2) | JP5840609B2 (enExample) |
| CN (1) | CN102497888B (enExample) |
| WO (1) | WO2011013038A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101906574B1 (ko) * | 2013-01-15 | 2018-10-10 | 주식회사 엘지생활건강 | 발수성을 가지는 칫솔모 및 이를 포함하는 칫솔 |
| CN118859065A (zh) * | 2024-07-01 | 2024-10-29 | 中国科学院精密测量科学与技术创新研究院 | 一种利用凝血级联放大提升19f mri肿瘤信噪比的方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4453028A (en) * | 1982-03-29 | 1984-06-05 | Lagow Richard J | Perfluorinated compounds with cyclohexyl groups |
| US5236694A (en) | 1990-02-21 | 1993-08-17 | The Board Of Regents, The University Of Texas System | 19f labelled dextrans and antibodies as nmr imaging and spectroscopy agents |
| US5571498A (en) | 1994-06-02 | 1996-11-05 | Hemagen/Pfc | Emulsions of paramagnetic contrast agents for magnetic resonance imaging (MRI). |
| US6167887B1 (en) * | 1997-11-21 | 2001-01-02 | Synthetic Blood International, Inc. | Selected C-10 perfluorinated hydrocarbons for liquid ventilation and artificial blood |
| US7220401B2 (en) * | 1999-09-24 | 2007-05-22 | Barnes-Jewish Hospital | Blood clot-targeted nanoparticles |
| US6676963B1 (en) * | 2000-10-27 | 2004-01-13 | Barnes-Jewish Hospital | Ligand-targeted emulsions carrying bioactive agents |
| US6574497B1 (en) * | 2000-12-22 | 2003-06-03 | Advanced Cardiovascular Systems, Inc. | MRI medical device markers utilizing fluorine-19 |
| US6869591B2 (en) * | 2002-03-26 | 2005-03-22 | Barnes-Jewish Hospital | Paramagnetic particles that provide improved relaxivity |
| US8777889B2 (en) * | 2004-06-15 | 2014-07-15 | Ceramatec, Inc. | Apparatus and method for administering a therapeutic agent into tissue |
| EP1817098A1 (en) | 2004-10-29 | 2007-08-15 | Koninklijke Philips Electronics N.V. | Method and apparatus for the preparation of dispersions of particles for use as contrast agents in ultrasound imaging |
| WO2007127958A2 (en) * | 2006-04-27 | 2007-11-08 | Barnes-Jewish Hospital | Detection and imaging of target tissue |
| JP5366824B2 (ja) * | 2006-12-19 | 2013-12-11 | コーニンクレッカ フィリップス エヌ ヴェ | ２次元ビデオの３次元ビデオへの変換方法及びシステム |
| EP2130058B1 (en) | 2007-03-19 | 2013-05-15 | Koninklijke Philips Electronics N.V. | Fast magnetic resonance spectroscopic imaging |
| EP1985312A1 (en) | 2007-04-25 | 2008-10-29 | Koninklijke Philips Electronics N.V. | T1 reduction in 19F magnetic resonance imaging (MRI) |
| KR101005561B1 (ko) * | 2008-06-21 | 2011-01-05 | 한국생명공학연구원 | 광학특성 나노입자 및 퍼플루오로카본으로 구성된 나노에멀젼을 이용한 다중모드 조영 방법 |
| CN102395548A (zh) * | 2009-04-15 | 2012-03-28 | 奥斯金生医公司 | 全氟化碳类乳液 |
-
2010
- 2010-07-21 JP JP2012522296A patent/JP5840609B2/ja not_active Expired - Fee Related
- 2010-07-21 WO PCT/IB2010/053321 patent/WO2011013038A2/en not_active Ceased
- 2010-07-21 EP EP10740399.0A patent/EP2459235B1/en not_active Not-in-force
- 2010-07-21 US US13/387,748 patent/US20120128589A1/en not_active Abandoned
- 2010-07-21 CN CN201080041769.8A patent/CN102497888B/zh not_active Expired - Fee Related
-
2015
- 2015-11-12 JP JP2015221770A patent/JP2016029098A/ja active Pending
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