JP2015534562A5 - - Google Patents
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- JP2015534562A5 JP2015534562A5 JP2015535058A JP2015535058A JP2015534562A5 JP 2015534562 A5 JP2015534562 A5 JP 2015534562A5 JP 2015535058 A JP2015535058 A JP 2015535058A JP 2015535058 A JP2015535058 A JP 2015535058A JP 2015534562 A5 JP2015534562 A5 JP 2015534562A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- pharmaceutically acceptable
- acceptable salt
- composition according
- inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261711136P | 2012-10-08 | 2012-10-08 | |
| US61/711,136 | 2012-10-08 | ||
| PCT/EP2013/070917 WO2014056894A1 (en) | 2012-10-08 | 2013-10-08 | Mek inhibitors in the treatment of virus diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018025712A Division JP2018118971A (ja) | 2012-10-08 | 2018-02-16 | ウイルス疾患の処置におけるｍｅｋ阻害物質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015534562A JP2015534562A (ja) | 2015-12-03 |
| JP2015534562A5 true JP2015534562A5 (https=) | 2016-11-24 |
| JP6294889B2 JP6294889B2 (ja) | 2018-03-14 |
Family
ID=49552318
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015535058A Expired - Fee Related JP6294889B2 (ja) | 2012-10-08 | 2013-10-08 | ウイルス疾患の処置におけるｍｅｋ阻害物質 |
| JP2018025712A Pending JP2018118971A (ja) | 2012-10-08 | 2018-02-16 | ウイルス疾患の処置におけるｍｅｋ阻害物質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018025712A Pending JP2018118971A (ja) | 2012-10-08 | 2018-02-16 | ウイルス疾患の処置におけるｍｅｋ阻害物質 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9566281B2 (https=) |
| EP (1) | EP2903649A1 (https=) |
| JP (2) | JP6294889B2 (https=) |
| KR (1) | KR102174576B1 (https=) |
| CN (2) | CN109276716B (https=) |
| AU (1) | AU2013328824B2 (https=) |
| BR (1) | BR112015007616B1 (https=) |
| CA (1) | CA2886138C (https=) |
| EA (1) | EA028605B1 (https=) |
| WO (1) | WO2014056894A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9181329B2 (en) * | 2007-08-31 | 2015-11-10 | The University Of Chicago | Methods and compositions related to immunizing against Staphylococcal lung diseases and conditions |
| BR112015007616B1 (pt) * | 2012-10-08 | 2022-08-09 | Atriva Therapeutics Gmbh | Uso de inibidores de mek em combinação com oseltamivir, e composição farmacêutica e seu uso |
| EA039897B1 (ru) | 2014-05-16 | 2022-03-24 | Атрива Терепьютикс Гмбх | Применение ингибитора мек для лечения коинфекции, включающей бактериальную инфекцию и инфекцию, вызванную вирусом гриппа |
| US20190183855A1 (en) * | 2016-08-10 | 2019-06-20 | Riken | Composition for treating hepatitis b, and method for evaluating replication activity of hepatitis b virus |
| JP2019535696A (ja) * | 2016-11-25 | 2019-12-12 | ジエンス ヘンルイ メデイシンカンパニー リミテッドＪｉａｎｇｓｕ Ｈｅｎｇｒｕｉ Ｍｅｄｉｃｉｎｅ Ｃｏ．，Ｌｔｄ． | ピリドン誘導体の医薬組成物およびその製造方法 |
| ES2928773T3 (es) | 2017-01-17 | 2022-11-22 | Heparegenix Gmbh | Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos |
| US11903917B2 (en) * | 2017-10-17 | 2024-02-20 | Atriva Therapeutics Gmbh | MEK-inhibitor for the treatment of viral and bacterial infections |
| US20190298669A1 (en) * | 2018-03-29 | 2019-10-03 | Atriva Therapeutics Gmbh | Ci-1040 for the treatment of viral diseases |
| EP3860598B1 (en) | 2018-10-03 | 2023-09-06 | Jyväskylän Yliopisto | Vemurafenib and salts thereof for use in the treatment of enteroviral infections |
| CN109765324B (zh) * | 2018-11-27 | 2021-03-30 | 苏州科技大学 | 一种mek1蛋白潜在抑制剂的筛选方法 |
| AU2020243160A1 (en) | 2019-03-19 | 2021-10-14 | Atriva Therapeutics Gmbh | Rsk inhibitors in the treatment of virus diseases |
| LU101183B1 (en) | 2019-04-16 | 2020-10-16 | Atriva Therapeutics Gmbh | Novel mek-inhibitor for the treatment of viral and bacterial infections |
| WO2021037956A1 (en) | 2019-08-27 | 2021-03-04 | Atriva Therapeutics Gmbh | Combinations of mek inhibitors with cap-dependent endonuclease inhibitors |
| EP4041212B1 (en) * | 2019-10-08 | 2025-07-23 | Atriva Therapeutics GmbH | Mek inhibitors for the treatment of hantavirus infections |
| WO2021214296A1 (en) * | 2020-04-24 | 2021-10-28 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Treatment of corona virus infections |
| CN111529532A (zh) * | 2020-05-05 | 2020-08-14 | 华中科技大学同济医学院附属协和医院 | 曲美替尼在制备治疗肺部炎症性疾病药物及促进Tfh细胞分化药物中的应用 |
| CN111494620A (zh) * | 2020-05-05 | 2020-08-07 | 华中科技大学同济医学院附属协和医院 | 曲美替尼在制备疫苗中的应用 |
| CN112137994B (zh) * | 2020-09-15 | 2022-10-14 | 中山大学 | 小分子化合物在制备抗丝状病毒药物中的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69131667D1 (de) | 1990-07-30 | 1999-11-04 | Procyon Pharm Inc | Proteinkinase-c-modulatoren mit entzündungshemmender und antiviraler aktivität |
| US5866601A (en) | 1995-02-27 | 1999-02-02 | Gilead Sciences, Inc. | Carbocyclic compounds |
| US5763483A (en) | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
| AU2203800A (en) * | 1999-01-07 | 2000-07-24 | Warner-Lambert Company | Antiviral method using mek inhibitors |
| DE10017480A1 (de) | 2000-04-07 | 2001-10-11 | Transmit Technologietransfer | Verwendung von Substanzen, die als MEK Inhibitor wirken, zur Herstellung eines Arneimittels gegen DNA- und RNA-Viren |
| DE10138912A1 (de) | 2001-08-08 | 2003-02-27 | Medinnova Ges Med Innovationen | Verwendung von Wirksubstanzen zur Prophylaxe und/oder Therapie von Viruserkrankungen sowie Testsystem zum Auffinden solcher Wirksubstanzen |
| CN102206216B (zh) * | 2005-06-22 | 2014-11-12 | 普莱希科公司 | 作为蛋白质激酶抑制剂的吡咯并[2,3-b]吡啶衍生物 |
| CN102036658A (zh) * | 2008-05-23 | 2011-04-27 | 香港大学 | 治疗流感的联合疗法 |
| BR112015007616B1 (pt) * | 2012-10-08 | 2022-08-09 | Atriva Therapeutics Gmbh | Uso de inibidores de mek em combinação com oseltamivir, e composição farmacêutica e seu uso |
-
2013
- 2013-10-08 BR BR112015007616-5A patent/BR112015007616B1/pt active IP Right Grant
- 2013-10-08 JP JP2015535058A patent/JP6294889B2/ja not_active Expired - Fee Related
- 2013-10-08 CA CA2886138A patent/CA2886138C/en active Active
- 2013-10-08 KR KR1020157010311A patent/KR102174576B1/ko active Active
- 2013-10-08 CN CN201810617076.7A patent/CN109276716B/zh active Active
- 2013-10-08 EA EA201590703A patent/EA028605B1/ru active IP Right Revival
- 2013-10-08 WO PCT/EP2013/070917 patent/WO2014056894A1/en not_active Ceased
- 2013-10-08 US US14/434,328 patent/US9566281B2/en not_active Expired - Fee Related
- 2013-10-08 AU AU2013328824A patent/AU2013328824B2/en not_active Ceased
- 2013-10-08 CN CN201380064116.5A patent/CN105101999B/zh active Active
- 2013-10-08 EP EP13788684.2A patent/EP2903649A1/en not_active Withdrawn
-
2017
- 2017-02-09 US US15/428,693 patent/US20170209450A1/en not_active Abandoned
-
2018
- 2018-02-16 JP JP2018025712A patent/JP2018118971A/ja active Pending
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